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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SH3BGRL Gene

protein-coding GIFtS: 56
GCID: GC0XP080457

SH3 domain binding glutamic acid-rich protein like

Explore 3 diseases affiliated with
SH3BGRL via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
SH3 Domain Binding Glutamic Acid-Rich Protein Like¹ ²
SH3BGR² ⁵
MGC117402¹
SH3 Domain-Binding Glutamic Acid-Rich-Like Protein²
SH3-Binding Domain Glutamic Acid-Rich Protein Like²

External Ids:	HGNC: 10823¹	Entrez Gene: 6451²	Ensembl: ENSG00000131171⁷	OMIM: 300190⁵	UniProtKB: O75368³

Export aliases for SH3BGRL gene to outside databases

Previous GC identifers: GC0XP076003 GC0XP077419 GC0XP078498 GC0XP079213 GC0XP080263 GC0XP074037

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for SH3BGRL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000023.10 NC_018934.1 NT_011651.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SH3BGRL gene promoter:
HOXA9B HOXA9 RP58 C/EBPbeta FOXO3 FOXO3b Meis-1b FOXO3a RSRFC4 Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SH3BGRL promoter sequence

Search SABiosciences Chromatin IP Primers for SH3BGRL

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SH3BGRL

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.3 Ensembl cytogenetic band: Xq21.1 HGNC cytogenetic band: Xq13.3

SH3BGRL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SH3BGRL gene location

GeneLoc information about chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP080457: view genomic region (about GC identifiers)

Start:	80,457,303 bp from pter	End:	80,554,046 bp from pter
Size:	96,744 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SH3L1_HUMAN, O75368 (See protein sequence)

Recommended Name: SH3 domain-binding glutamic acid-rich-like protein

Size: 114 amino acids; 12774 Da

2 PDB 3D structures from and Proteopedia for SH3BGRL:

1U6T (3D)

1WRY (3D)

Secondary accessions: Q3SYL1 Q5JT50 Q6FIE8 Q9H0N8

Explore the universe of human proteins at neXtProt for SH3BGRL: NX_O75368

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O75368

SH3BGRL Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_003013.1

ENSEMBL proteins:

ENSP00000362308

Human Recombinant Protein Products:

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	Novus Biologicals SH3BGRL Proteins Novus Biologicals SH3BGRL Lysates
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for SH3BGRL
	Uscn Proteins for SH3BGRL

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	TAS	16130169
GO:0005737	cytoplasm	TAS	16130169

SH3BGRL for ontologies About GeneDecksing

SH3BGRL Antibody Products:

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	Novus Biologicals SH3BGRL Antibodies
	Search for Antibodies for SH3BGRL at Abcam
	Uscn Antibodies for SH3BGRL
	Search ThermoFisher Antibodies for SH3BGRL

Assay Products for SH3BGRL:

	Browse Kits and Assays available from EMD Millipore
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	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SH3BGRL
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SH3BGRL

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SH3BGRL for domains About GeneDecksing

2 InterPro domains/families:

IPR006993 Glut_rich_SH3-bd

IPR012336 Thioredoxin-like_fold

Graphical View of Domain Structure for InterPro Entry O75368

ProtoNet protein and cluster: O75368

1 Blocks protein family: IPB006993 SH3-binding

UniProtKB/Swiss-Prot: SH3L1_HUMAN, O75368

Similarity: Belongs to the SH3BGR family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

Genatlas biochemistry entry for SH3BGRL:

SH3 domain binding,glutamic acid protein-like,widely expressed

miRNA Products:		OriGene 3'-UTR Clone: SH3BGRL Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SH3BGRL
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate SH3BGRL (see all 16):
		hsa-miR-548j hsa-miR-548w hsa-miR-3163 hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-548c-5p hsa-miR-548y

		SwitchGear 3'UTR luciferase reporter plasmid: SH3BGRL 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SH3BGRL (see all 4) OriGene shRNA RFP: SH3BGRL OriGene siRNA: SH3BGRL
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SH3BGRL

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SH3BGRL

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BGRL (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BGRL OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SH3BGRL (NM_003022)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SH3BGRL
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SH3BGRL
		Search LifeMap BioReagents cell lines for SH3BGRL

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3BGRL

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005070	SH3/SH2 adaptor activity	TAS	9642120
GO:0017124	SH3 domain binding	IEA	--

SH3BGRL for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

EGFR1 Signaling Pathway

EGFR1 Signaling Pathway

1.00

1 BioSystems Pathway for SH3BGRL

EGFR1 Signaling Pathway

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SH3BGRL

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5 Interacting proteins for SH3BGRL (O75368^{2, 3} ENSP00000362308⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EGFR	P00533²^,³, ENSP00000275493⁴	MINT-61483 I2D: score=3 STRING: ENSP00000275493
ATG5	Q9H1Y0³	I2D: score=1
ERBB2	P04626³	I2D: score=1
IL7R	P16871³	I2D: score=1
TPT1	ENSP00000368350⁴	STRING: ENSP00000368350

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SH3BGRL
Search CenterWatch for drugs/clinical trials and news about SH3BGRL / SH3L1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SH3BGRL gene:

NM_003022.2

Unigene Cluster for SH3BGRL:

SH3 domain binding glutamic acid-rich protein like

Hs.108029 [show with all ESTs]

Unigene Representative Sequence: NM_003022

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000373212(uc004eef.3 uc011mqs.2 uc010nml.3 uc010nmm.3 uc010nmn.3)

ENST00000481106 ENST00000463546 ENST00000474113

miRNA Products:		OriGene 3'-UTR Clone: SH3BGRL Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SH3BGRL
		8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate SH3BGRL (see all 16):
		hsa-miR-548j hsa-miR-548w hsa-miR-3163 hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-548c-5p hsa-miR-548y

		SwitchGear 3'UTR luciferase reporter plasmid: SH3BGRL 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SH3BGRL (see all 4) OriGene shRNA RFP: SH3BGRL OriGene siRNA: SH3BGRL
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SH3BGRL

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BGRL (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SH3BGRL OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SH3BGRL (NM_003022)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SH3BGRL
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SH3BGRL

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SH3BGRL Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SH3BGRL
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3BGRL

Additional cDNA sequence:

AF042081.1 AK024892.1 AK129610.1 AK309350.1 AK309351.1 AK309352.1 AK310011.1 AK310155.1

AK315897.1 AL136718.1 BC016709.1 BC103762.1 CR533478.1

22 DOTS entries:

DT.80101740 DT.101981144 DT.100845614 DT.100845613 DT.121321260 DT.100845612 DT.99956343 DT.100845611

DT.87017199 DT.100845628 DT.95117451 DT.121321192 DT.121321250 DT.91770810 DT.100701582 DT.100845608

DT.121321196 DT.121321203 DT.121321282 DT.121321290 DT.91770798 DT.99979017

24/564 AceView cDNA sequences (see all 564):

AI589471 AA034026 AI041371 AW188906 AA233655 BQ899237 AI805736 BP349835

BQ717246 BI792957 BP342128 CA449722 CR615275 AI336777 AI434645 W19682

AI185768 AA854450 BU072130 BP337625 AW515435 AI937153 BU631298 AW591665

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SH3BGRL (see all 7) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8a	·	8b	^	9a	·	9b	·	9c	·	9d	·	9e
SP1:									-		-		-		-										-
SP2:													-		-		-								-
SP3:									-		-		-		-		-								-
SP4:																	-								-
SP5:									-		-		-		-		-				-				-

ECgene alternative splicing isoforms for SH3BGRL

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SH3BGRL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGATTCAAAC

About this image

SH3BGRL expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Reproductive System

Testis

Kidney

Reproductive System

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SH3BGRL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SH3BGRL

SOURCE GeneReport for Unigene cluster: Hs.108029

UniProtKB/Swiss-Prot: SH3L1_HUMAN, O75368

Tissue specificity: Ubiquitous

SABiosciences Custom PCR Arrays for SH3BGRL

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SH3BGRL

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SH3BGRL

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for SH3BGRL gene from 6/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Sh3bgrl^{1 , 5}	SH3-binding domain glutamic acid-rich protein like^{1, 5}	92.69(n)¹ 94.74(a)¹		X (47.92 cM)⁵ 56726¹ NM_019989.2¹ NP_064373.1¹ 109095365⁵
chicken (Gallus gallus)	Aves	SH3BGRL¹	SH3 domain binding glutamic acid-rich protein like	80.12(n) 86.84(a)		422277 NM_001012574.1 NP_001012592.1
lizard (Anolis carolinensis)	Reptilia	SH3BGRL⁶	--	85(a)	1 ↔ 1	GL343202.1(20006-51358)
zebrafish (Danio rerio)	Actinopterygii	zgc64130²	similar to SH3 domain binding glutamic acid-rich protein more	75.05(n)		394184 BC054623.1
fruit fly (Drosophila melanogaster)	Insecta	Sh3beta⁶	Sh3beta	8(a)	1 → many	3L(7357684-7362360)
worm (Caenorhabditis elegans)	Secernentea	Y105E8A.1⁶	--	27(a)	1 → many	I(14341621-14343793)

ENSEMBL Gene Tree for SH3BGRL (if available)
TreeFam Gene Tree for SH3BGRL (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SH3BGRL gene

SH3BGRL2² SH3BGR² SH3BGRL3²

3 SIMAP similar genes for SH3BGRL using alignment to 2 protein entries: SH3L1_HUMAN (see all proteins):

SH3BGRL2 SH3BGR SH3BGRL3

SH3BGRL for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr X pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs138165055^1,2		--	80455422(+)	`ACTATC/GATCAG`	2	--	int¹ us2k¹		0	--	--	--	--
rs182128220^1,2		--	80455584(+)	`TCTCAA/GAAGAA`	2	--	int¹ us2k¹		0	--	--	--	--
rs142275461^1,2		--	80455615(+)	`ACATAC/TGCAAA`	2	--	int¹ us2k¹		0	--	--	--	--
rs113848219^1,2	C	--	80455619(+)	`ATGAAC/AAAAAG`	2	--	int¹ us2k¹		2		NA	4
rs76489739^1,2	C	--	80455646(+)	`ATTAGG/AGAAAT`	2	--	us2k¹ int¹		1		WA	2
rs187213675^1,2		--	80455652(+)	`GAAATA/GCAAAT`	2	--	us2k¹ int¹		0	--	--	--	--
rs12986451^1,2	C,F	--	80455786(-)	`cttccG/Acaatg`	2	--	int¹ us2k¹		2		NA CSA	4
rs35168889^1,2	C,F	--	80455909(-)	`ACATAC/TGTGTG`	2	--	int¹ us2k¹		2		NA	4
rs5959839^1,2	C,	--	80455933(+)	`attcaT/Caatag`	2	--	us2k¹ int¹		2		NA	4
rs188431528^1,2		--	80455944(+)	`CAAAGA/GCTTGG`	2	--	us2k¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SH3BGRL (80457303 - 80554046 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SH3BGRL: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SH3BGRL

DNA2.0 Custom Variant and Variant Library Synthesis for SH3BGRL

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SH3BGRL for disorders           About GeneDecksing

OMIM gene information: 300190    OMIM disorders: --

3 diseases for SH3BGRL:    About MalaCards

down syndrome endocarditis obesity

1 disease from the University of Copenhagen DISEASES database for SH3BGRL:

Down syndrome

Human Genome Epidemiology (HuGE) Navigator: SH3BGRL (1 document)

Export disorders for SH3BGRL gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SH3BGRL gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with SH3BGRL)

Utopia: connect your pdf to the dynamic
world of online information

Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene. (PubMed id 9642120)^{1, 2, 3, 9} Egeo A.... Scartezzini P. (1998)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{1, 2} Ross M.T.... Bentley D.R. (2005)
Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins. (PubMed id 16080146)^{1, 2} Yin L.... Wang D.C. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Use of genome-wide expression data to mine the ' Gray Zone' of GWA studies leads to novel candidate obesity genes. (PubMed id 20532202)¹ Naukkarinen J....Peltonen L. (2010)
The suppression of SH3BGRL is important for v-Rel-mediated transformation. (PubMed id 16186799)¹ Majid S.M....Bose H.R. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 6451	HGNC: 10823	AceView: SH3BGRL	Ensembl:ENSG00000131171	euGenes: HUgn6451
ECgene: SH3BGRL	H-InvDB: SH3BGRL

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SH3BGRL	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SH3BGRL gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SH3BGRL gene:
Search GeneIP for patents involving SH3BGRL

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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SH3BGRL Gene

SH3 domain binding glutamic acid-rich protein like

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SH3BGRL Gene

SH3 domain binding glutamic acid-rich protein like

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for SH3BGRL gene

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for SH3BGRL gene

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for SH3BGRL gene

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