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SH2D4A Gene

protein-coding   GIFtS: 53
GCID: GC08P019215

SH2 Domain Containing 4A

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SH2 Domain Containing 4A1 2     Protein Phosphatase 11
PPP1R382 3 5     Regulatory Subunit 381
SH2A2 3 5     Protein Phosphatase 1, Regulatory Subunit 382
Protein Phosphatase 1 Regulatory Subunit 382 3     SH2 Domain-Containing Protein 4A2
Protein SH(2)A2 3     

External Ids:    HGNC: 261021   Entrez Gene: 638982   Ensembl: ENSG000001046117   OMIM: 6149685   UniProtKB: Q9H7883   

Export aliases for SH2D4A gene to outside databases

Previous GC identifers: GC08P019182 GC08P017711


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SH2D4A Gene:
SH2D4A (SH2 domain containing 4A) is a protein-coding gene. GO annotations related to this gene include phosphatase binding. An important paralog of this gene is SH2D7.

UniProtKB/Swiss-Prot: SH24A_HUMAN, Q9H788
Function: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the
effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development
and function

Gene Wiki entry for SH2D4A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_167187.2  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SH2D4A gene promoter:
         p53   FOXD1   HNF-1A   SRY   FOXC1   FOXJ2 (long isoform)   HNF-1   HFH-1   Sox9   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSH2D4A promoter sequence
   Search Chromatin IP Primers for SH2D4A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SH2D4A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p21.2   Ensembl cytogenetic band:  8p21.3   HGNC cytogenetic band: 8p21

SH2D4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SH2D4A gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P019215:  view genomic region     (about GC identifiers)

Start:
19,171,081 bp from pter      End:
19,253,729 bp from pter
Size:
82,649 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SH24A_HUMAN, Q9H788 (See protein sequence)
Recommended Name: SH2 domain-containing protein 4A  
Size: 454 amino acids; 52727 Da
Subunit: Interacts with ESR1
Sequence caution: Sequence=AAH67117.1; Type=Frameshift; Positions=392; Sequence=AAO41715.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=AAO41715.1; Type=Erroneous termination;
Positions=455; Note=Translated as stop; Sequence=BAB14935.1; Type=Erroneous initiation;
Secondary accessions: B4DDR1 Q5XKC1 Q6NXE9 Q86YM2 Q96C88 Q9H7F7
Alternative splicing: 2 isoforms:  Q9H788-1   Q9H788-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SH2D4A: NX_Q9H788

Explore proteomics data for SH2D4A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SH2D4A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001167630.1  NP_001167631.1  NP_071354.2  

    ENSEMBL proteins: 
     ENSP00000265807   ENSP00000429482   ENSP00000428684   ENSP00000428048  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PPP1R: Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits
    SH2D: SH2 domain containing

    1 InterPro protein domain:
     IPR000980 SH2

    Graphical View of Domain Structure for InterPro Entry Q9H788

    ProtoNet protein and cluster: Q9H788

    1 Blocks protein domain: IPB000980 SH2 domain signature

    UniProtKB/Swiss-Prot: SH24A_HUMAN, Q9H788
    Similarity: Contains 1 SH2 domain


    Find genes that share domains with SH2D4A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SH24A_HUMAN, Q9H788
    Function: Inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the
    effect of estrogen on PLCG and repressing estrogen-induced proliferation. May play a role in T-cell development
    and function

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16189514
    GO:0019902phosphatase binding IDA19389623
         
    Find genes that share ontologies with SH2D4A           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Sh2d4a):
     no phenotypic analysis  normal 

    Find genes that share phenotypes with SH2D4A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Sh2d4atm1.1Pdk for SH2D4A

       genOway: Develop your customized and physiologically relevant rodent model for SH2D4A

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SH24A_HUMAN, Q9H788: Cytoplasm. Note=Located at podocyte foot processes (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    nucleus4

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with SH2D4A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SH2D4A
    Interactions:

        Search GeneGlobe Interaction Network for SH2D4A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    Selected Interacting proteins for SH2D4A (Q9H7881, 2, 3 ENSP000002658074) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DBNLQ9UJU61, 2, 3EBI-747035,EBI-751783 MINT-68272 I2D: score=5 
    MAGEA11P433641, 2, 3, ENSP000003473584EBI-747035,EBI-739552 MINT-67945 I2D: score=6 STRING: ENSP00000347358
    SH3GL1Q999611, 3, ENSP000002698864EBI-747035,EBI-697911 I2D: score=4 STRING: ENSP00000269886
    HCLS1P143172, 3, ENSP000003201764MINT-67768 I2D: score=5 STRING: ENSP00000320176
    PPP1CBP621403, ENSP000002961224I2D: score=2 STRING: ENSP00000296122
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010923negative regulation of phosphatase activity IDA19389623

    Find genes that share ontologies with SH2D4A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for SH2D4A (SH24A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SH2D4A gene (3 alternative transcripts): 
    NM_001174159.1  NM_001174160.1  NM_022071.3  

    Unigene Cluster for SH2D4A:

    SH2 domain containing 4A
    Hs.303208  [show with all ESTs]
    Unigene Representative Sequence: NM_022071
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000265807(uc003wzb.3 uc011kym.2 uc003wzc.3) ENST00000518040
    ENST00000519207 ENST00000523736 ENST00000518093 ENST00000522328
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    hsa-miR-205 hsa-miR-198 hsa-miR-377 hsa-miR-2113 hsa-miR-1205
    SwitchGear 3'UTR luciferase reporter plasmidSH2D4A 3' UTR sequence
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    Additional mRNA sequence: 

    AK024620.1 AK024799.1 AK225052.1 AK293301.1 AY190323.1 BC014525.2 BC067117.1 BC082982.1 

    6 DOTS entries:

    DT.305655  DT.97791812  DT.101970436  DT.97840908  DT.100774810  DT.120649743 

    Selected AceView cDNA sequences (see all 118):

    BX431828 AW951924 BU543213 CA446151 BX484872 BC014525 CB243542 BM826296 
    BM709025 CA418381 AA977843 BU625855 BM827287 AW673002 C00748 BP364899 
    BU732479 BM714882 CD723532 BM856853 BE898238 BU521838 AW675171 CB124498 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SH2D4A    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b
    SP1:        -                                               -                                   -               
    SP2:                                                        -                                   -               
    SP3:                                      -                                                                     
    SP4:                                                                                                            
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for SH2D4A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SH2D4A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SH2D4A Expression
    About this image


    SH2D4A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Pre-Sertoli Cells Testis Cord
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    SH2D4A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SH2D4A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.303208

    UniProtKB/Swiss-Prot: SH24A_HUMAN, Q9H788
    Tissue specificity: Ubiquitously expressed. Aberrantly expressed in some cancers

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SH2D4A gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sh2d4a1 , 5 SH2 domain containing 4A1, 5 79.33(n)1
    78.15(a)1
      8 (33.76 cM)5
    722811  NM_028182.11  NP_082458.11 
     682765675 
    chicken
    (Gallus gallus)
    Aves SH2D4A1 SH2 domain containing 4A 64.65(n)
    61.07(a)
      422487  XM_420452.4  XP_420452.1 
    lizard
    (Anolis carolinensis)
    Reptilia SH2D4A6
    SH2 domain containing 4A
    57(a)
    1 ↔ 1
    6(58977618-59017286)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sh2d4a1 SH2 domain containing 4A 57.88(n)
    53.18(a)
      780161  NM_001079236.2  NP_001072704.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561862 hypothetical protein MGC56186 74.88(n)   393219  BC047841.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F13B12.61 F13B12.6 48.66(n)
    40.9(a)
      177933  NM_171414.4  NP_741483.2 


    ENSEMBL Gene Tree for SH2D4A (if available)
    TreeFam Gene Tree for SH2D4A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SH2D4A gene
    SH2D72  SH2D2A2  SH2D4B2  
    1 SIMAP similar gene for SH2D4A using alignment to 2 protein entries:     SH24A_HUMAN (see all proteins):
    SH2D4B

    Find genes that share paralogs with SH2D4A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SH2D4A (see all 2151)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1846078151,2
    --19169087(+) TGAACC/TCAGGA 2 -- us2k10--------
    rs96930571,2
    C--19169192(+) aaTTCG/AAATTG 2 -- us2k14Minor allele frequency- A:0.34NA WA EA 360
    rs1870876001,2
    --19169314(+) GAGGAC/GAGGGG 2 -- us2k10--------
    rs356676781,2
    C,F--19169374(+) AAGAGT/ATCATG 2 -- us2k16Minor allele frequency- A:0.14NA CSA WA EA 363
    rs1454017621,2
    --19169400(+) AGCCAC/TGAGAC 2 -- us2k10--------
    rs1918838991,2
    --19169408(+) GACAAC/GAAGGA 2 -- us2k10--------
    rs1158599441,2
    C--19169445(+) GAAGAA/GAGTCT 2 -- us2k10--------
    rs1388786181,2
    --19169512(+) TATTAC/TTTCAA 3 -- us2k10--------
    rs1420125791,2
    --19169557(+) CTGAAA/GTGGCA 3 -- us2k10--------
    rs1843635511,2
    --19169628(+) GGGAGC/GTATGC 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for SH2D4A (19171081 - 19253729 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SH2D4A (see all 13):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1412941CNV Deletion17803354
    esv1003522CNV Deletion20482838
    nsv6103CNV Insertion18451855
    nsv528004CNV Loss19592680
    nsv522774CNV Loss19592680
    nsv398156CNV Loss16902084
    nsv890621CNV Loss21882294
    esv34007CNV Loss18971310
    nsv523271CNV Loss19592680
    nsv890622CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614968    OMIM disorders: --


    Find genes that share disorders with SH2D4A           About GenesLikeMe

    Genetic Association Database (GAD): SH2D4A
    Human Genome Epidemiology (HuGE) Navigator: SH2D4A (1 document)

    Export disorders for SH2D4A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SH2D4A gene, integrated from 10 sources (see all 29):
    (articles sorted by number of sources associating them with SH2D4A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. SH2D4A regulates cell proliferation via the ERalpha/PLC-gamma/PKC pathway. (PubMed id 19712589)1, 2 Li T.... Zhao Y. (BMB Rep. 2009)
    3. Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. (PubMed id 18641339)1, 2 Lapinski P.E....King P.D. (J. Immunol. 2008)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. A novel member of SH(2) signaling protein family: cloning and characterization of SH(2)A gene. (PubMed id 12476414)1, 2 Dai S.... Ding Q. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002)
    9. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
    10. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 63898 HGNC: 26102 AceView: SH2D4A Ensembl:ENSG00000104611 euGenes: HUgn63898
    ECgene: SH2D4A H-InvDB: SH2D4A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SH2D4A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SH2D4A gene:
    Search GeneIP for patents involving SH2D4A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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