Aliases for SH2D1B Gene
External Ids for SH2D1B Gene
Previous GeneCards Identifiers for SH2D1B Gene
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SH2D1B Gene
SH2D1B (SH2 Domain Containing 1B) is a Protein Coding gene. Diseases associated with SH2D1B include superior mesenteric artery syndrome. Among its related pathways are Immune System and Immune response Role of DAP12 receptors in NK cells. GO annotations related to this gene include protein binding, bridging. An important paralog of this gene is SH2D1A.
UniProtKB/Swiss-Prot for SH2D1B Gene
Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells