Aliases for SH2D1B Gene
External Ids for SH2D1B Gene
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]
GeneCards Summary for SH2D1B Gene
SH2D1B (SH2 Domain Containing 1B) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells. GO annotations related to this gene include protein binding, bridging and SH3/SH2 adaptor activity. An important paralog of this gene is SH2D1A.
UniProtKB/Swiss-Prot for SH2D1B Gene
Plays a role in controlling signal transduction through at least four receptors, CD84, SLAMF1, LY9 and CD244, expressed on the surface of professional antigen-presenting cells