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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SGTB Gene

protein-coding GIFtS: 44
GCID: GC05M065000

small glutamine-rich tetratricopeptide repeat (TPR)-containing,...

Search for SGTB
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Small Glutamine-Rich Tetratricopeptide Repeat (TPR)-Containing, Beta¹ ²		Beta-SGT³
Small Glutamine-Rich Protein With Tetratricopeptide Repeats 2² ³		Small Glutamine Rich Protein With Tetratricopeptide Repeats 2²
SGT2² ³		Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Beta²
FLJ39002¹		Beta-SGT³
Sgt2¹

External Ids:	HGNC: 23567¹	Entrez Gene: 54557²	Ensembl: ENSG00000197860⁷	UniProtKB: Q96EQ0³

Export aliases for SGTB gene to outside databases

Previous GC identifers: GC05M064980 GC05M064979 GC05M061917

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SGTB_HUMAN, Q96EQ0

Function: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.1 NT_006713.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SGTB gene promoter:
GR STAT1 Lmo2 STAT1beta STAT1alpha E47 Max GR-alpha c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SGTB promoter sequence

Search SABiosciences Chromatin IP Primers for SGTB

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGTB

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q12.3 Ensembl cytogenetic band: 5q12.3 HGNC cytogenetic band: 5q12.3

SGTB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SGTB gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M065000: view genomic region (about GC identifiers)

Start:	64,961,755 bp from pter	End:	65,018,862 bp from pter
Size:	57,108 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SGTB_HUMAN, Q96EQ0 (See protein sequence)

Recommended Name: Small glutamine-rich tetratricopeptide repeat-containing protein beta

Size: 304 amino acids; 33429 Da

Subunit: Homooligomerize (By similarity)

Explore the universe of human proteins at neXtProt for SGTB: NX_Q96EQ0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96EQ0

SGTB Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_061945.1

ENSEMBL proteins:

ENSP00000370395 ENSP00000421447

Human Recombinant Protein Products for SGTB:

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	Browse Proteins at Uscn

SGTB Antibody Products:

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	ThermoFisher Antibodies for SGTB

Assay Products for SGTB:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SGTB
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SGTB for domains About GeneDecksing

4 InterPro domains/families:

IPR001440 TPR-1

IPR011990 TPR-like_helical

IPR013026 TPR-contain_dom

IPR019734 TPR_repeat

Graphical View of Domain Structure for InterPro Entry Q96EQ0

ProtoNet protein and cluster: Q96EQ0

UniProtKB/Swiss-Prot: SGTB_HUMAN, Q96EQ0

Similarity: Belongs to the SGT family

Similarity: Contains 4 TPR repeats

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: SGTB_HUMAN, Q96EQ0

Function: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity (By similarity)

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SGTB

miRNA Products:		OriGene 3'-UTR Clone: SGTB Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SGTB
		8/70 QIAGEN miScript miRNA Assays for microRNAs that regulate SGTB (see all 70):
		hsa-miR-323-3p hsa-miR-579 hsa-miR-300 hsa-miR-106a hsa-miR-3138 hsa-miR-519a hsa-miR-3142 hsa-miR-629*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SGTB (see all 7) OriGene shRNA RFP: SGTB OriGene siRNA: SGTB
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SGTB
		Sirion Biotech Custom design and validation of potent shRNA sequences against SGTB

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SGTB
			Sirion Biotech Customized adenovirus for overexpression of SGTB Sirion Biotech Customized adenovirus for potent knockdown of SGTB

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SGTB (NM_019072)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SGTB
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGTB

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SGTB
		Search LifeMap BioReagents cell lines for SGTB
		Sirion Biotech Customized stable knockdown cell line services for SGTB Sirion Biotech Customized inducible knockdown cell line services for SGTB Sirion Biotech Customized stable overexpressing cell line services for SGTB Sirion Biotech Customized inducible overexpressing cell line services for SGTB

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGTB

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SGTB

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/10 Interacting proteins for SGTB (Q96EQ0^{2, 3} ENSP00000370395⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EFEMP2	O95967²^,³, ENSP00000309953⁴	MINT-66443 I2D: score=4 STRING: ENSP00000309953
RAI2	Q9Y5P3²^,³, ENSP00000333456⁴	MINT-67571 I2D: score=4 STRING: ENSP00000333456
TMPO	P42166³, ENSP00000266732⁴	I2D: score=1 STRING: ENSP00000266732
PPIB	P23284³	I2D: score=1
SERPINI2	O75830³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SGTB
Search CenterWatch for drugs/clinical trials and news about SGTB

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SGTB gene:

NM_019072.2

Unigene Cluster for SGTB:

Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta

Hs.482301 [show with all ESTs]

Unigene Representative Sequence: NM_019072

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000381007(uc003jud.3) ENST00000506816

miRNA Products:		OriGene 3'-UTR Clone: SGTB Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SGTB
		8/70 QIAGEN miScript miRNA Assays for microRNAs that regulate SGTB (see all 70):
		hsa-miR-323-3p hsa-miR-579 hsa-miR-300 hsa-miR-106a hsa-miR-3138 hsa-miR-519a hsa-miR-3142 hsa-miR-629*

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SGTB (see all 7) OriGene shRNA RFP: SGTB OriGene siRNA: SGTB
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SGTB
		Sirion Biotech Custom design and validation of potent shRNA sequences against SGTB

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SGTB (NM_019072)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SGTB
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGTB

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGTB Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGTB
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGTB

Additional cDNA sequence:

AF075050.1 AF368281.1 AK096321.1 BC012044.1

5 DOTS entries:

DT.113866 DT.40287888 DT.95172533 DT.305397 DT.120812722

21 AceView cDNA sequences:

AL713334 BC012044 AI280930 BG214707 NM_019072 AF075050 AK096321 AI420520

AF368281 BF978355 CB988961 BF984153 BE392704 BE671098 BG209490 BF984266

AA308206 AW951938 H41196 BE646024 BI049110

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SGTB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATAATGGG

About this image

SGTB expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Retina

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SGTB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SGTB

SOURCE GeneReport for Unigene cluster: Hs.482301

SABiosciences Custom PCR Arrays for SGTB

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGTB Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SGTB
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGTB
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGTB

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGTB

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SGTB gene from 10/29 species (see all 29) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Sgtb^{1 , 5}	small glutamine-rich tetratricopeptide repeat (TPR)-containing, more^{1, 5}	87.72(n)¹ 96.38(a)¹		13 (56.23 cM)⁵ 218544¹ NM_144838.1¹ NP_659087.1¹ 104109741⁵
chicken (Gallus gallus)	Aves	SGTB¹	small glutamine-rich tetratricopeptide repeat (TPR)-containing, more	80.37(n) 85.86(a)		427166 NM_001031418.1 NP_001026589.1
lizard (Anolis carolinensis)	Reptilia	SGTB⁶	--	85(a)	1 ↔ 1	2(10761255-10775456)
African clawed frog (Xenopus laevis)	Amphibia	Xl.13292²	Xenopus laevis transcribed sequence with moderate similarity more	75(n)		BJ067633.1
zebrafish (Danio rerio)	Actinopterygii	sgta¹	small glutamine-rich tetratricopeptide repeat (TPR)-containing, more	68.53(n) 73.68(a)		431772 NM_001002225.1 NP_001002225.1
fruit fly (Drosophila melanogaster)	Insecta	Sgt¹	small glutamine-rich tetratricopeptide containing protein	48.39(n) 37.45(a)		35052 NM_135998.2 NP_609842.1
worm (Caenorhabditis elegans)	Secernentea	sgt-1⁶	Small Glutamine-rich Tetratrico repeat protein fam...	32(a)	1 → many	II(4902283-4903791)
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	TAH1(YCR060W)⁴ SGT2¹	HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 more⁴ Sgt2p¹	46.74(n)¹ 36.09(a)¹		3(224399-224734)⁴ 854168¹ NP_014649.1¹ 850424⁴ NP_009986.1⁴
thale cress (Arabidopsis thaliana)	eudicotyledons	TPR8⁶ TPR3⁶	tetratricopeptide repeat-containing protein	21(a) 15(a)	many → 1 possible ortholog	4(5252811-5255200) 1(1106428-1108715)
rice (Oryza sativa)	Liliopsida	-- --	expressed protein tetratricopeptide repeat domain containing protein...	23(a) 16(a)	many → 1 possible ortholog	4(35125144-35130958) 12(25494698-25499127)

ENSEMBL Gene Tree for SGTB (if available)
TreeFam Gene Tree for SGTB (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SGTB gene

STUB1² TTC12² SGTA²

5 SIMAP similar genes for SGTB using alignment to 2 protein entries: SGTB_HUMAN (see all proteins):

H_YN88E09.1 SGTA STIP1 PPP5C SUGT1P3

SGTB for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs192471807^1,2		--	64961267(+)	`GTAATG/TGTTTG`	5	--	ut3¹ ds500¹		0	--	--	--	--
rs183897400^1,2		--	64961584(+)	`GAAAGC/TTGAGG`	5	--	ds500¹ ut3¹		0	--	--	--	--
rs188177989^1,2		--	64961766(+)	`TTTCAA/GTGCAT`	5	--	ut3¹		0	--	--	--	--
rs147875976^1,2	C	--	64962234(+)	`GCATA-/TAT AGAACCTGTTC`	5	--	ds500¹ ut3¹		0	--	--	--	--
rs140821140^1,2		--	64962467(+)	`TTGAAA/GTAGCT`	1	--	ut3¹		0	--	--	--	--
rs181399973^1,2		--	64962599(+)	`AGCAAA/GGAAAT`	1	--	ut3¹		0	--	--	--	--
rs150131304^1,2		--	64962692(+)	`ATGAAA/GACATT`	1	--	ut3¹		0	--	--	--	--
rs72764483^1,2	C	--	64962816(+)	`ATATTA/GTTTCT`	1	--	ut3¹		3		NA EA	242
rs116117019^1,2	C,F	--	64962855(+)	`GGAAGT/CTATCT`	1	--	ut3¹		1		WA	118
rs184557585^1,2		--	64962863(+)	`TCTGGA/GCCTGT`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SGTB (64961755 - 65018862 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SGTB
1 CNV: 51723

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGTB

DNA2.0 Custom Variant and Variant Library Synthesis for SGTB

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SGTB gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with SGTB)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 54557	HGNC: 23567	AceView: SGTB	Ensembl:ENSG00000197860	euGenes: HUgn54557
ECgene: SGTB	H-InvDB: SGTB

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SGTB	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SGTB gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SGTB gene:
Search GeneIP for patents involving SGTB

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	EMD Millipore Custom Antibody & Bulk Services
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	Browse OriGene Antibodies		OriGene shRNA RFP for SGTB
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SGTB		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGTB
	OriGene Protein Over-expression Lysate for SGTB		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SGTB		OriGene 3'-UTR Clone for SGTB
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGTB
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for SGTB		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SGTB		OriGene Custom Protein Services for SGTB
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SGTB
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGTB
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGTB
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SGTB
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGTB
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGTB

	GenScript Custom Purified and Recombinant Proteins Services for SGTB		GenScript cDNA clones with any tag delivered in your preferred vector for SGTB
	GenScript Custom Assay Services for SGTB		GenScript Custom Superior Antibodies Services for SGTB
	GenScript Custom overexpressing Cell Line Services for SGTB		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	Regulatory tfbs in SGTB promoter
	Search Chromatin IP Primers for SGTB
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Search Tocris compounds for SGTB

	Browse Sino Biological Proteins and Antibodies
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	SGTB antibodies
	SGTB proteins
	SGTB lysates

	Antibodies for SGTB
	See all of Abcam's Antibodies, Kits and Proteins for SGTB
	Custom Antibody / Protein Production Service
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	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn

Search LifeMap BioReagents cell lines for SGTB

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGTB

	Browse SwitchGear 3'UTR luciferase reporter plasmids for SGTB
	SwitchGear Promoter luciferase reporter plasmids for SGTB

ThermoFisher Antibodies for SGTB

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGTB

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for SGTB

Sirion Biotech Customized:

	stable knockdown cell line services for SGTB
	inducible knockdown cell line services for SGTB
	design and validation of potent shRNA sequences against SGTB
	adenovirus for potent knockdown of SGTB
	adenovirus for overexpression of SGTB
	stable overexpressing cell line services for SGTB
	inducible overexpressing cell line services for SGTB

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SGTB gene at Home site.

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SGTB Gene

small glutamine-rich tetratricopeptide repeat (TPR)-containing,...

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SGTB Gene

small glutamine-rich tetratricopeptide repeat (TPR)-containing,...

Aliasesfor SGTB gene

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Genomic Viewsfor SGTB gene

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Protein Domains /Familiesfor SGTB gene

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for SGTB gene

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for SGTB gene

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for SGTB gene

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Orthologs
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for SGTB gene

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for SGTB gene

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