SGSH Gene
protein-coding GIFtS: 62
GCID: GC17M078183
|
|
N-sulfoglucosamine sulfohydrolase
| |
Aliases
for SGSH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| N-Sulfoglucosamine Sulfohydrolase1 2 | | Mucopolysaccharidosis Type IIIA2 | | HSS1 2 3 | | N-Sulphoglucosamine Sulphohydrolase2 | | MPS3A1 2 5 | | Sulphamidase3 | | SFMD1 2 5 | | EC 3.10.1.13 | | Sulfoglucosamine Sulfamidase2 3 | | Sulphamidase3 | | Heparan Sulfate Sulfatase2 | | |
Export aliases for SGSH gene to outside databasesPrevious GC identifers: GC17U990093 GC17M081486 GC17M078745 GC17M078883 GC17M075797 GC17M073623 |
Summaries
for SGSH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SGSH:
This gene encodes one of several enzymes involved in the lysosomal degradation of heparan sulfate. Mutations in thisgene are associated with Sanfilippo syndrome A, one type of the lysosomal storage disease mucopolysaccaridosis III,which results from impaired degradation of heparan sulfate. Transcripts of varying sizes have been reported but theirbiological validity has not been determined. (provided by RefSeq, Jul 2008)
Gene Wiki entry for SGSH
|
Genomic Views
for SGSH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SGSH gene promoter:
AREB6 Lmo2 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for SGSH
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGSH |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.3 Ensembl cytogenetic band: 17q25.3 HGNC cytogenetic band: 17q25.3SGSH Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M078183: view genomic region
(about GC identifiers)
Start:
|
78,180,515 bp from pter |
End:
|
78,194,722 bp from pter |
Size:
|
14,208 bases |
Orientation:
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minus strand |
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Proteins
for SGSH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SPHM_HUMAN, P51688 (See
protein sequence)Recommended Name: N-sulphoglucosamine sulphohydrolase precursor Size: 502 amino acids; 56695 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Subcellular location: Lysosome
Secondary accessions: A8K5E2Explore the universe of human proteins at neXtProt for SGSH: NX_P51688
Post-translational modifications:
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotesand of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P51688
SGSH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000190.1
ENSEMBL proteins: ENSP00000461827 ENSP00000314606 ENSP00000459280 ENSP00000460720 ENSP00000458200 ENSP00000461160 ENSP00000459708 ENSP00000461128 ENSP00000459765 ENSP00000437778 Reactome Protein details: P51688
Human Recombinant Protein Products for SGSH:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SGSH for ontologies About GeneDecksing
SGSH Antibody Products:
Assay Products for SGSH: |
Protein
Domains /
Families
for SGSH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SGSH for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P51688ProtoNet protein and cluster: P51688 1 Blocks protein family: IPB000917 Sulfatase
UniProtKB/Swiss-Prot: SPHM_HUMAN, P51688Similarity: Belongs to the sulfatase family |
Function
for SGSH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SPHM_HUMAN, P51688Catalytic activity: N-sulfo-D-glucosamine + H(2)O = D-glucosamine + sulfate Genatlas biochemistry entry for SGSH:sulfamidase,lysosomal,acting on heparan sulfate,catalyzing the third step of degradation of glucosaminoglycans(mucopolysaccharides)
Enzyme Number (IUBMB): EC 3.10.1.11
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
SGSH for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for SGSH:
13 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Sgsh):
SGSH for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SGSH (NM_000199) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SGSH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGSH |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGSH |
|
Pathways & Interactions
for SGSH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | MPS IIIC - Sanfilippo syndrome C | | | 2 | Metabolism | | | 3 | Disease | | | 4 | Lysosome | | | 5 | Glycosaminoglycan degradation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/18 
Reactome Pathways for SGSH (see all 18)
3 
Kegg Pathways (Kegg details for SGSH):
SGSH for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SGSH
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for SGSH (ENSP000003146064) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005975 | carbohydrate metabolic process |
TAS | -- | | GO:0006027 | glycosaminoglycan catabolic process |
TAS | -- | | GO:0006029 | proteoglycan metabolic process |
TAS | 7493035 | | GO:0030203 | glycosaminoglycan metabolic process |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- |
SGSH for ontologies About GeneDecksing
|
Drugs & Compounds
for SGSH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SGSH for compounds About GeneDecksing
 Browse Tocris compounds for SGSH
2 HMDB Compounds for SGSH About this table
2 Novoseek chemical compound relationships for SGSH gene About this table
Search CenterWatch for drugs/clinical trials and news about SGSH / SPHM
|
Transcripts
for SGSH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SGSH gene: NM_000199.3 Unigene Cluster for SGSH: N-sulfoglucosamine sulfohydrolase Hs.31074 [show with all ESTs]Unigene Representative Sequence: NM_00019918 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000575484 ENST00000571156 ENST00000572257 ENST00000326317(uc002jxz.4 uc002jya.4)
ENST00000575282(uc002jxy.2) ENST00000573150 ENST00000576856 ENST00000570923(uc010wue.1)
ENST00000576941 ENST00000574505 ENST00000572208 ENST00000571051 ENST00000576707
ENST00000570427 ENST00000571675 ENST00000575188 ENST00000571075 ENST00000534910
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SGSH (NM_000199) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SGSH | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGSH |
Additional cDNA sequence: AK095969.1 AK222890.1 AK291257.1 AK304706.1 AK309927.1 BC047318.1 U30894.1 9 DOTS entries: DT.97838326 DT.91876590 DT.100708779 DT.112320 DT.120944816 DT.120944862 DT.91748206 DT.100784097 DT.95277130 24/135 AceView cDNA sequences (see all 135): AA312469 BM818396 BM695105 BG829585 AU099199 CB988539 BQ002677 BP365415 CD607804 BQ675535 BI823800 CB961545 BU553673 AL543497 BU734616 BU685248 CA454045 BQ669835 AI363945 BQ227740 BU621458 BX387226 BP364345 CD368281
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SGSH (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | - | | - | | - | | - | | | |
ECgene alternative splicing isoforms for SGSH
|
Expression
for SGSH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SGSH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCGATGCCCG
About this image
See SGSH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SGSH
SOURCE GeneReport for Unigene cluster: Hs.31074
SABiosciences Custom PCR Arrays for SGSH
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGSH
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SGSH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGSH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGSH | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGSH |
Orthologs
for SGSH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SGSH gene from 6/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Sgsh1 , 5 |
N-sulfoglucosamine sulfohydrolase (sulfamidase)1, 5 |
84.59(n)1
88.65(a)1 |
|
11 (83.36 cM)5
270291 NM_018822.31 NP_061292.21
1193434255 |
chicken
(Gallus gallus) |
Aves |
SGSH1 |
N-sulfoglucosamine sulfohydrolase |
79.63(n)
81.87(a) |
|
422081 XM_420084.3 XP_420084.3 |
lizard
(Anolis carolinensis) |
Reptilia |
SGSH6 |
-- |
76(a) |
1 ↔ 1 |
2(100555199-100562776) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.249512 |
Xenopus laevis transcribed sequence with moderate similarity more |
72.28(n) |
|
BX842936.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
sgsh1 |
N-sulfoglucosamine sulfohydrolase (sulfamidase) |
67.48(n)
71.81(a) |
|
563849 NM_001123268.1 NP_001116740.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG142911 , 3 |
N-sulfoglucosamine sulfohydrolase3
CG142911 |
54(a)3
57.83(n)1
56.73(a)1 |
|
91D43
422661 NM_142503.31 NP_650760.11 |
ENSEMBL Gene Tree for SGSH (if available)
TreeFam Gene Tree for SGSH (if available) |
Paralogs
for SGSH gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SGSH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SGSH (78180515 - 78194722 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SGSH
1 CNV: 2235
Human Gene Mutation Database (HGMD): SGSH
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGSH |
|
Disorders
/ Diseases
for SGSH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SGSH for disorders About GeneDecksing
OMIM gene information: 605270
OMIM disorders: 252900
UniProtKB/Swiss-Prot: SPHM_HUMAN, P51688
Defects in SGSH are the cause of mucopolysaccharidosis type 3A (MPS3A) [MIM:252900]; also known as Sanfilipposyndrome A. MPS3A is a severe form of mucopolysaccharidosis type 3, an autosomal recessive lysosomal storage diseasedue to impaired degradation of heparan sulfate. MPS3 is characterized by severe central nervous system degeneration,but only mild somatic disease. Onset of clinical features usually occurs between 2 and 6 years; severe neurologicdegeneration occurs in most patients between 6 and 10 years of age, and death occurs typically during the second orthird decade of life. MPS3A is characterized by earlier onset, rapid progression of symptoms and shorter survival
10  diseases for SGSH: About MalaCardslysosomal storage disease mucopolysaccharidisis type iiia (sanfilippo a) mucopolysaccharidosis beta-mannosidosis
mucopolysaccharidosis iii mannosidosis hepatitis b hepatitis
tuberculosis mycobacterium tuberculosis
3 diseases from the University of Copenhagen DISEASES database for SGSH:Mucopolysaccharidosis Mucosulfatidosis Metachromatic leukodystrophy 4 Novoseek disease relationships for SGSH gene About this table
Human Genome Epidemiology (HuGE) Navigator: SGSH (1 document)
Export disorders for SGSH gene to outside databases
|
Publications
for SGSH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SGSH gene, integrated from 9 sources (see all 49):
(articles sorted by number of sources associating them with SGSH) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome. (PubMed id 7493035)1, 2, 3 Scott H.S.... Hopwood J.J. (1995)
- The mutation p.Ser298Pro in the sulphamidase gene (SGSH) is associated with a slowly progressive clinical phenotype in mucopolysaccharidosis type IIIA (Sanfilippo A syndrome). (PubMed id 18407553)1, 2, 9 Meyer A.... Muschol N. (2008)
- Transport, enzymatic activity, and stability of mutant sulfamidase (SGSH) identified in patients with mucopolysaccharidosis type III A. (PubMed id 15146460)1, 2, 9 Muschol N....Braulke T. (2004)
- Early diagnosis of mucopolysaccharidosis III A with a nonsense mutation and two de novo missense mutations in SGSH gene. (PubMed id 15902564)1, 2, 9 Bekri S....Froissart R. (2005)
- Sanfilippo syndrome in Turkey: Identification of novel mutations in subtypes A and B. (PubMed id 11793481)1, 2, 9 Emre S....Hopwood J.J. (2002)
- Residual activity and proteasomal degradation of p.Ser298Pro sulfamidase identified in patients with a mild clinical phenotype of Sanfilippo A syndrome. (PubMed id 21671382)1, 2 Muschol N.... Braulke T. (2011)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Analysis of Sanfilippo A gene mutations in a large pedigree. (PubMed id 12702166)1, 2 Di Natale P.... Bartuli A. (2003)
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. (PubMed id 12754519)1, 2 Zhang H.... Aebersold R. (2003)
|
External Searches for SGSH gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SGSH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SGSH gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SGSH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SGSH | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/IDS |
|
| | |
About This Section
| Patent Information for SGSH gene:
Search GeneIP for patents involving SGSH
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SGSH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | OriGene Antibodies for SGSH | | OriGene shRNA RFP for SGSH | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SGSH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGSH | | | OriGene Protein Over-expression Lysate for SGSH | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SGSH | | OriGene 3'-UTR Clone for SGSH | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGSH | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SGSH | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SGSH | | OriGene Custom Protein Services for SGSH | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SGSH | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGSH | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGSH | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SGSH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGSH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGSH |
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| | | | Search Tocris compounds for SGSH |
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 | | | SGSH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGSH |
|  |  |  |  | | | | ThermoFisher Antibodies for SGSH |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGSH |
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