SGPL1 Gene
protein-coding GIFtS: 62
GCID: GC10P072575
|
|
sphingosine-1-phosphate lyase 1
| |
Aliases for SGPL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Sphingosine-1-Phosphate Lyase 11 2 | | SP-Lyase 12 3 | | SPL1 2 5 | | SPL 12 3 | | Sphingosine-1-Phosphate Aldolase2 3 | | EC 4.1.2.273 | | S1PL2 3 | | KIAA12523 | | HSPL1 | | |
Export aliases for SGPL1 gene to outside databasesPrevious GC identifers: GC10P071360 GC10P071679 GC10P072468 GC10P071920 GC10P072245 GC10P066569 |
Summaries for SGPL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470Function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes andphosphoethanolamine. Elevates stress-induced ceramide production and apoptosis Gene Wiki entry for SGPL1
|
Genomic Views for SGPL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SGPL1 gene promoter: TBP Egr-1 RelA Meis-1b GATA-1 MEF-2A aMEF-2 Meis-1a Meis-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for SGPL1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGPL1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q21 Ensembl cytogenetic band: 10q22.1 HGNC cytogenetic band: 10q21SGPL1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P072575: view genomic region
(about GC identifiers)
Start:
|
72,575,704 bp from pter |
End:
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72,640,946 bp from pter |
Size:
|
65,243 bases |
Orientation:
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plus strand |
|
Proteins for SGPL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470 (See
protein sequence)Recommended Name: Sphingosine-1-phosphate lyase 1 Size: 568 amino acids; 63524 Da
Cofactor: Pyridoxal phosphate (By similarity)
Subcellular location: Endoplasmic reticulum membrane; Single-pass type III membrane protein
Sequence caution: Sequence=BAA86566.1; Type=Erroneous initiation;
Secondary accessions: B2RBD4 Q7Z732 Q9ULG8 Q9UN89Explore the universe of human proteins at neXtProt for SGPL1: NX_O95470
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95470 SGPL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003892.2 ENSEMBL proteins: ENSP00000362298 ENSP00000299297 ENSP00000386549 Reactome Protein details: O95470 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
SGPL1 for ontologies About GeneDecksing
SGPL1 Antibody Products: Assay Products for SGPL1: |
Protein
Domains / Families for SGPL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SGPL1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95470ProtoNet protein and cluster: O95470 UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470Similarity: Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily |
Function for SGPL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470Function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes andphosphoethanolamine. Elevates stress-induced ceramide production and apoptosisCatalytic activity: Sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde Genatlas biochemistry entry for SGPL1:sphingosine-1-phosphate lyase 1,pyridoxal dependent,involved in the proliferative signal transduction pathways Enzyme Number (IUBMB): EC 4.1.2.271
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SGPL1 (NM_003901) | |  | Sino Biological Human cDNA Clone for SGPL1 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SGPL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGPL1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGPL1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SGPL1 for ontologies About GeneDecksing
Animal Models: 15/17 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Sgpl1) (see all 17):
SGPL1 for phenotypes About GeneDecksing
|
Pathways & Interactions for SGPL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | Metabolism | | | 3 | S1P3 pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
1 BioSystems Pathway for SGPL1 
4
Reactome Pathways for SGPL1
2
Kegg Pathways (Kegg details for SGPL1): UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470Pathway: Lipid metabolism; sphingolipid metabolism
SGPL1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SGPL1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
 5/41 Interacting proteins for SGPL1 (O954701, 3 ENSP000003622984) via UniProtKB, MINT, STRING, and/or I2D (see all 41) About this table
Gene Ontology (GO): 5/25 biological process terms (GO ID links to tree view) (see all 25): About this table
SGPL1 for ontologies About GeneDecksing
|
Drugs & Compounds for SGPL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SGPL1 for compounds About GeneDecksing
Browse Tocris compounds for SGPL1
10/38 HMDB Compounds for SGPL1 (see all 38) About this table
1 DrugBank Compound for SGPL1 About this table
1 Novoseek chemical compound relationship for SGPL1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sphingosine |
59.6 |
1 |
15258913 (1) |
Search CenterWatch for drugs/clinical trials and news about SGPL1 
|
Transcripts for SGPL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for SGPL1 gene: NM_003901.3 Unigene Cluster for SGPL1: Sphingosine-1-phosphate lyase 1 Hs.499984 [show with all ESTs]Unigene Representative Sequence: NM_0039014 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000486993(uc001jrl.2) ENST00000373202(uc001jrm.3 uc009xqk.3) ENST00000299297 ENST00000409118
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SGPL1 (NM_003901) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SGPL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGPL1  |
Additional cDNA sequence: AB033078.1 AF144638.1 AJ011304.2 AK023873.1 AK308610.1 AK314615.1 BC031338.1 BC041567.1 BC051238.1 BC052991.1 BC068061.1 12 DOTS entries: DT.216906 DT.99934933 DT.100789416 DT.100010662 DT.91748919 DT.121264661 DT.65284746 DT.70103051 DT.95308624 DT.95214309 DT.91744923 DT.97776403 24/259 AceView cDNA sequences (see all 259): BQ778468 AI739573 BU627688 BX371476 BC068061 BF513285 BU608120 AI301617 BX282607 AI633968 AA733213 AW574730 BQ679149 AA442998 AI767378 AA338781 BM556374 CB214990 AB033078 AW590282 BI253944 AI613091 R84511 NM_003901 GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SGPL1 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for SGPL1
|
Expression for SGPL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SGPL1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTTTATTATT
About this image See SGPL1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SGPL1
SOURCE GeneReport for Unigene cluster: Hs.499984 UniProtKB/Swiss-Prot: SGPL1_HUMAN, O95470Tissue specificity: Found in liver and kidney SABiosciences Expression via Pathway-Focused PCR Array including SGPL1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGPL1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SGPL1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGPL1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGPL1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGPL1 |
Orthologs for SGPL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for SGPL1 gene from 11/34 species (see all 34) About this table
ENSEMBL Gene Tree for SGPL1 (if available) TreeFam Gene Tree for SGPL1 (if available)  |
Paralogs for SGPL1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for SGPL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for SGPL1 (72575704 - 72640946 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for SGPL1 2 CNVs: 48626 48625  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGPL1 |
|
Disorders
/ Diseases for SGPL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SGPL1 for disorders About GeneDecksing
OMIM gene information: 603729
OMIM disorders: --
10 diseases for SGPL1: About MalaCardsatopic dermatitis pituitary adenoma colon cancer dermatitis adenoma alzheimer's disease influenza lung cancer tuberculosis mycobacterium tuberculosis
4 Novoseek disease relationships for SGPL1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: SGPL1 (2 documents) Export disorders for SGPL1 gene to outside databases
|
Publications for SGPL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SGPL1 gene, integrated from 9 sources (see all 51): (articles sorted by number of sources associating them with SGPL1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer. (PubMed id 17090686)1, 3, 9 Oskouian B....Saba J.D. (2006)
- Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PubMed id 16777052)1, 2, 9 Zhan X. and Desiderio D.M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis. (PubMed id 14570870)1, 2 Reiss U.... Saba J.D. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22. (PubMed id 11018465)1, 2 Van Veldhoven P.P....Brys V. (2000)
- Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (1999)
- Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast. (PubMed id 9464245)1, 3 Zhou J. and Saba J.D. (1998)
- First evidence of sphingosine 1-phosphate lyase protei n expression and activity downregulation in human neoplasm: implication for resi stance to therapeutics in prostate cancer. (PubMed id 22784711)1 Brizuela L....Cuvillier O. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
|
External Searches for SGPL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing SGPL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SGPL1 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SGPL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for SGPL1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SGPL1 gene: Search GeneIP for patents involving SGPL1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for SGPL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for SGPL1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SGPL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SGPL1 | | OriGene Protein Over-expression Lysate for SGPL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for SGPL1 | | OriGene 3'-UTR Clone for SGPL1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SGPL1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for SGPL1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for SGPL1 | | OriGene Custom Protein Services for SGPL1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SGPL1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SGPL1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGPL1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SGPL1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGPL1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SGPL1 |
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 |  |  |  | |
| | | Search Tocris compounds for SGPL1 |
| |  |  |  |  | | | | |
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 | | SGPL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGPL1 |
|  |  |  | | | ThermoFisher Antibodies for SGPL1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGPL1 |
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