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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SGCE Gene

protein-coding   GIFtS: 61
GCID: GC07M094214

Sarcoglycan, Epsilon


(Previous symbol: DYT11)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sarcoglycan, Epsilon1 2     epsilon-SG2
DYT111 2 5     epsilon-sarcoglycan2
ESG2 3     Epsilon-SG3
Dystonia 11, Myoclonic2     

External Ids:    HGNC: 108081   Entrez Gene: 89102   Ensembl: ENSG000001279907   OMIM: 6041495   UniProtKB: O435563   

Export aliases for SGCE gene to outside databases

Previous GC identifers: GC07M092749 GC07M093812 GC07M093826 GC07M093859 GC07M094052 GC07M088821


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SGCE Gene:
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are
components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix.
Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more
broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is
imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants
encoding different isoforms have been found for this gene.(provided by RefSeq, Oct 2010)

GeneCards Summary for SGCE Gene: 
SGCE (sarcoglycan, epsilon) is a protein-coding gene. Diseases associated with SGCE include myoclonus-dystonia, and dystonia-11, myoclonic. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is SGCA.

UniProtKB/Swiss-Prot: SGCE_HUMAN, O43556
Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a
link between the F-actin cytoskeleton and the extracellular matrix

Gene Wiki entry for SGCE Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SGCE gene promoter:
         C/EBPbeta   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): SGCE promoter sequence
   Search SABiosciences Chromatin IP Primers for SGCE

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SGCE


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.3   Ensembl cytogenetic band:  7q21.3   HGNC cytogenetic band: 7q21.3

SGCE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SGCE gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M094214:  view genomic region     (about GC identifiers)

Start:
94,214,536 bp from pter      End:
94,285,521 bp from pter
Size:
70,986 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 93,543,689-93,614,670     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SGCE_HUMAN, O43556 (See protein sequence)
Recommended Name: Epsilon-sarcoglycan  
Size: 437 amino acids; 49851 Da
Subcellular location: Cell membrane, sarcolemma; Single-pass membrane protein (Potential). Cytoplasm, cytoskeleton
(By similarity)
Sequence caution: Sequence=AAC04368.1; Type=Erroneous initiation;
Secondary accessions: B2R8N2 D6W5Q8 E9PF60 Q6L8P0 Q75MH8 Q8NFG8 Q8WW28
Alternative splicing: 2 isoforms:  O43556-1   O43556-3   (Brain-specific)

Explore the universe of human proteins at neXtProt for SGCE: NX_O43556

Explore proteomics data for SGCE at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43556

  • SGCE Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SGCE Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001092870.1  NP_001092871.1  NP_003910.1  

    ENSEMBL proteins: 
     ENSP00000431080   ENSP00000265735   ENSP00000398930   ENSP00000394061   ENSP00000388734  
     ENSP00000397536   ENSP00000405313   ENSP00000398344   ENSP00000391892  

    Human Recombinant Protein Products for SGCE: 
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    Novus Biologicals SGCE Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0005887integral to plasma membrane TAS9475163
    GO:0016010dystrophin-associated glycoprotein complex IDA17993586
    GO:0016012sarcoglycan complex IEA--

    SGCE for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR006644 Cadg
     IPR008908 Sarcoglycan_2

    Graphical View of Domain Structure for InterPro Entry O43556

    ProtoNet protein and cluster: O43556

    2 Blocks protein domains:
    IPB006644 Dystroglycan-type cadherin-like domain
    IPB008908 Sarcoglycan alphaepsilon


    UniProtKB/Swiss-Prot: SGCE_HUMAN, O43556
    Similarity: Belongs to the sarcoglycan alpha/epsilon family


    SGCE for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SGCE_HUMAN, O43556
    Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a
    link between the F-actin cytoskeleton and the extracellular matrix

         Genatlas biochemistry entry for SGCE:
    sarcoglycan epsilon,dystrophin associated protein,broadly expressed in muscle and non muscle cells of embryo and
    adult,associating with other sarcoglycans,stabilizing the link between dystroglycan and dystrophin/utrophin

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    SGCE for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Sgce):
     behavior/neurological  cardiovascular system  cellular  immune system  muscle 
     nervous system 

    SGCE for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Sgcetm1Ygl for SGCE

       inGenious Targeting Laboratory - Custom generated mouse model solutions for SGCE 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SGCE

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SGCE 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SGCE 

    miRNA
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate SGCE (see all 15):
    hsa-miR-142-5p hsa-miR-495 hsa-miR-520d-5p hsa-miR-429 hsa-miR-7-2* hsa-miR-586 hsa-miR-374c hsa-miR-200c
    SwitchGear 3'UTR luciferase reporter plasmidSGCE 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    Sino Biological Human cDNA Clone for SGCE
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                         Customized lentivirus expression plasmids for stable overexpression of SGCE 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGCE


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SGCE

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/34 Interacting proteins for SGCE (O435562, 3 ENSP000003989304) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARIH2O953762, 3MINT-63288 I2D: score=5 
    TLE1ENSP000003656824STRING: ENSP00000365682
    CAV3ENSP000003419404STRING: ENSP00000341940
    DAG1ENSP000003124354STRING: ENSP00000312435
    DMDENSP000003549234STRING: ENSP00000354923
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007160cell-matrix adhesion TAS9405466
    GO:0007517muscle organ development TAS9405466

    SGCE for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SGCE for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SGCE

    1 Novoseek inferred chemical compound relationship for SGCE gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    peg-10 93.2 7 12620933 (2), 19171046 (1), 18480470 (1), 11318613 (1) (see all 5)

    Search CenterWatch for drugs/clinical trials and news about SGCE

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SGCE gene (3 alternative transcripts): 
    NM_001099400.1  NM_001099401.1  NM_003919.2  

    Unigene Cluster for SGCE:

    Sarcoglycan, epsilon
    Hs.371199  [show with all ESTs]
    Unigene Representative Sequence: AK295021
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000522045 ENST00000265735(uc003unm.2 uc003unl.2 uc003unn.2 uc011kic.1)
    ENST00000445866 ENST00000437425 ENST00000447873 ENST00000428696 ENST00000472326
    ENST00000415788(uc011kid.1) ENST00000462731 ENST00000450385 ENST00000425444

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SGCE
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate SGCE (see all 15):
    hsa-miR-142-5p hsa-miR-495 hsa-miR-520d-5p hsa-miR-429 hsa-miR-7-2* hsa-miR-586 hsa-miR-374c hsa-miR-200c
    SwitchGear 3'UTR luciferase reporter plasmidSGCE 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SGCE
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SGCE
    Sirion Biotech Customized lentivirus for stable overexpression of SGCE 
                         Customized lentivirus expression plasmids for stable overexpression of SGCE 
    Primer
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    OriGene qPCR primer pairs and template standards for SGCE
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    Additional mRNA sequence: 

    AB117974.1 AF031920.1 AF036364.1 AF516515.1 AJ000534.1 AK295021.1 AK298220.1 AK313438.1 
    AY359042.1 BC021709.2 

    13 DOTS entries:

    DT.100786625  DT.452904  DT.91746569  DT.100786623  DT.100786620  DT.40121592  DT.100762448  DT.95173187 
    DT.91681096  DT.95173186  DT.99950015  DT.40121591  DT.92034733 

    24/157 AceView cDNA sequences (see all 157):

    AA447965 NM_003919 AA232128 CD723702 CD722975 AI648380 BI755437 BQ932247 
    BQ893748 BX280159 AL547670 CR591589 BX280837 AL702273 AJ000534 AI374598 
    BE220963 BM725390 CD677242 CR597920 BQ574050 BX387203 AI221799 BQ879635 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SGCE (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b · 14c
    SP1:                                -     -     -                                                           -           -                 -                     
    SP2:                                -     -     -                                                           -     -     -                                       
    SP3:                                            -                                                                                                               
    SP4:                                                                                                        -     -     -                 -                     
    SP5:                                -     -     -     -                                                                                                         


    ECgene alternative splicing isoforms for SGCE

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SGCE expression in normal human tissues (normalized intensities)      SGCE embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGCAGTAT
    SGCE Expression
    About this image


    SGCE expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Endothelium (Cardiovascular System)
             Peripheral blood endothelial colony-forming cells
     
     Eye (Sensory Organs)
             Mature Rod Bipolar Cells Inner Nuclear Layer

    See SGCE Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SGCE

    SOURCE GeneReport for Unigene cluster: Hs.371199

    UniProtKB/Swiss-Prot: SGCE_HUMAN, O43556
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including SGCE: 
              Extracellular Matrix & Adhesion Molecules in human mouse rat

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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SGCE
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SGCE

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SGCE gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sgce1 , 5 sarcoglycan, epsilon1, 5 89.66(n)1
    95.6(a)1
      6 (1.81 cM)5
    203921  NM_001130188.11  NP_001123660.11 
     46743505 
    chicken
    (Gallus gallus)
    Aves SGCE1 sarcoglycan, epsilon 84.56(n)
    94.68(a)
      420567  XM_003640683.1  XP_003640731.1 
    lizard
    (Anolis carolinensis)
    Reptilia SGCE6
    sarcoglycan, epsilon
    79(a)
    1 ↔ 1
    6(22277574-22308691)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.27202 Transcribed sequence with weak similarity to protein more 74.21(n)    57050708 
    fruit fly
    (Drosophila melanogaster)
    Insecta Scgalpha6
    Sarcoglycan alpha
    20(a)
    1 → many
    2L(8303429-8305376)


    ENSEMBL Gene Tree for SGCE (if available)
    TreeFam Gene Tree for SGCE (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SGCE gene
    SGCA2  
    1 SIMAP similar gene for SGCE using alignment to 7 protein entries:     SGCE_HUMAN (see all proteins):
    SGCA

    SGCE for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SGCE
    PGOHUM00000240376


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    947/1175 SNPs in SGCE are shown (see all 1175)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0667344
    Dystonia 11 (DYT11)4--see VAR_0667342 H R mis40--------
    VAR_0667404
    Dystonia 11 (DYT11)4--see VAR_0667402 S C mis40--------
    VAR_0667334
    Dystonia 11 (DYT11)4--see VAR_0667332 H P mis40--------
    VAR_0667434
    Dystonia 11 (DYT11)4--see VAR_0667432 C Y mis40--------
    VAR_0667394
    Dystonia 11 (DYT11)4--see VAR_0667392 L S mis40--------
    VAR_0667424
    Dystonia 11 (DYT11)4--see VAR_0667422 W R mis40--------
    VAR_0667384
    Dystonia 11 (DYT11)4--see VAR_0667382 Y C mis40--------
    VAR_0667414
    Dystonia 11 (DYT11)4--see VAR_0667412 L P mis40--------
    VAR_0667364
    Dystonia 11 (DYT11)4--see VAR_0667362 W G mis40--------
    VAR_0267504
    Dystonia 11 (DYT11)4--see VAR_0267502 L R mis40--------
    VAR_0667324
    Dystonia 11 (DYT11)4--see VAR_0667322 T R mis40--------
    VAR_0667374
    Dystonia 11 (DYT11)4--see VAR_0667372 G R mis40--------
    VAR_0667354
    Dystonia 11 (DYT11)4--see VAR_0667352 M T mis40--------
    rs346575721,2
    C--88854423(+) ACCTACT/-CCCAC 3 -- int11Minor allele frequency- -:0.50NA 2
    rs345420791,2
    C--88858679(+) TACACAT/-GTTTA 3 -- int12Minor allele frequency- -:0.25NA CSA 4
    rs347471231,2
    C,F--88888576(+) TCTTCT/-TTATT 3 -- int12Minor allele frequency- -:0.50NA 4
    rs2000390261,2
    C--88888577(+) TTCTT-/TATTATT 3 -- int10--------
    rs722748681,2
    C--88891278(+) ATTTT-/TCTC  
            
    CTAAT
    3 -- int10--------
    rs585883441,2
    C--88891279(+) TTTCT-/CTCT  
            
    AATAA
    3 -- int10--------
    rs133074031,2
    C--88892901(+) ccccaA/Ccccca 3 -- us2k1 tfbs30--------
    rs585331481,2
    C--94215978(+) TTTTT-/TGTATT 3 -- int10--------
    rs343119001,2
    C--94216269(+) ACTGT-/GTACTTT 3 -- int10--------
    rs720893951,2
    C--94226865(+) TGTATGA/-GAGAG 3 -- int11Minor allele frequency- -:0.50CSA 2
    rs613298861,2
    C--94233726(+) ACACA-/ACA   
      C
    /CACA
    AATTT
    3 -- int10--------
    rs2016258611,2
    --94234134(+) TATAT-/AATATA 3 -- int10--------
    rs1878122781,2
    --94234170(+) ATATAA/TAATAG 3 -- int10--------
    rs58858711,2
    C--94244678(+) AATAA-/ATA   
       GATAG
    ATAGA
    3 -- int10--------
    rs3679093971,2
    C--94248336(+) AACAA-/ATTTGC 3 -- int10--------
    rs2012673731,2
    C--94253492(-) CATTTG/TTTTTT 3 -- int10--------
    rs347038411,2
    C--94257450(+) ACACA-/AC/CA 
            
    TATAT
    3 -- int10--------
    rs712929701,2
    C--94260463(-) ATGAATACTAG/-
            
    TACTA
    3 -- cds11Minor allele frequency- -:0.50NA 2
    rs360315931,2
    C--94271067(+) CCTTC-/AAAAAT 3 -- int11Minor allele frequency- A:0.50NA 2
    rs715280931,2
    C--94279911(+) ATCAG-/AAAAAA 3 -- int11Minor allele frequency- A:0.50NA 2
    rs350111671,2
    C--94285096(+) AAAAAAAA/-GGCCA 3 -- cds11Minor allele frequency- -:0.50NA 2
    rs734254341,2
    C,F--97520662(+) GCAAGA/GTACTC 3 -- ds50014Minor allele frequency- G:0.41WA CSA 124
    rs1862247911,2
    --97520828(+) AAGTAC/TGCAGC 3 -- ds50010--------
    rs1172735721,2
    C,F--97520837(+) GCGTGG/AGCTGC 3 -- ds50011Minor allele frequency- A:0.01NA 120
    rs1910759681,2
    --97520896(+) TATTCA/GAAAAC 3 -- ds50010--------
    rs1828117221,2
    --97520939(+) ACAGGC/TCACAA 3 -- ds50010--------
    rs1458245681,2
    --97521104(+) TAGTTG/TACTGA 3 -- ds50010--------
    rs119841481,2
    C,H--97521131(+) CATTAG/AGCTTC 3 -- ut314Minor allele frequency- A:0.00NS EA 420
    rs1885262461,2
    --97521193(+) CATCAA/GTGTTT 3 -- ut310--------
    rs1931723061,2
    --97521302(+) TAACAC/TATGCC 3 -- ut310--------
    rs102258621,2
    C,A,H--97521667(+) ACAGTC/TTGAAA 3 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1477744131,2
    --97521764(+) ATGTGA/GGCTGG 3 -- int10--------
    rs1410904561,2
    --97521842(+) TAGTGC/TAATTG 3 -- int10--------
    rs737206911,2
    C,F--97521861(+) TAACTG/ACTCTA 3 -- int13Minor allele frequency- A:0.05WA CSA 122
    rs1828666151,2
    --97521862(+) AACTGC/TTCTAT 3 -- int10--------
    rs102262061,2
    C,H--97521921(+) CATTTC/TTTAAA 3 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1146470361,2
    F--97522037(+) TAGGTA/GGCTAC 3 -- int11Minor allele frequency- G:0.03WA 118
    rs1882930271,2
    --97522122(+) ATAATA/GTTCTG 3 -- int10--------
    rs1913814561,2
    --97522139(+) TTGGAA/CAACTC 3 -- int10--------
    rs734254361,2
    C--97522281(+) CAGATG/AGAAGA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs2019392741,2
    --97522405(+) TTTTC-/TTTTTT 3 -- int10--------
    rs1839558571,2
    --97522406(+) TTTTCC/TTTTTT 3 -- int10--------
    rs1877953751,2
    --97522421(+) TTTTTC/TGATTC 3 -- int10--------
    rs117701221,2
    H--97522428(+) attcaA/Gagtct 3 -- int10--------
    rs117701251,2
    H--97522448(+) gcccaA/Ggctgg 3 -- int10--------
    rs1469108911,2
    --97522486(+) GCAACA/CTCCAC 3 -- int10--------
    rs1926222431,2
    C--97522491(+) CTCCAC/TCTCCC 3 -- int10--------
    rs1857461951,2
    --97522610(+) CATGTC/TGGGCA 3 -- int10--------
    rs117701811,2
    H--97522611(+) atgtcA/Gggcag 3 -- int10--------
    rs18514221,2
    C,F,A,H--97522702(-) GAGGCT/CGGGTG 3 -- int120Minor allele frequency- C:0.28NS EA NA WA CSA 2090
    rs2009477141,2
    C--97522860(+) GATAC-/TGTGTAC 3 -- int10--------
    rs1898735331,2
    --97522907(+) TAAGAA/GAACAA 3 -- int10--------
    rs102240501,2
    C,F--97523009(+) AATAAT/CTTTAT 3 -- int12Minor allele frequency- C:0.04NA WA 120
    rs1177134971,2
    C,F--97523019(+) TAAATT/GAGGTT 3 -- int11Minor allele frequency- G:0.03EA 120
    rs1389329291,2
    --97523090(+) TGTCCG/TTGTAT 3 -- int10--------
    rs1819294441,2
    --97523167(+) ACTACC/TAAACA 3 -- int10--------
    rs1845911171,2
    --97523194(+) TCTACC/TCAAGT 3 -- int10--------
    rs1494133321,2
    --97523330(+) AGAAGA/TTAGAA 3 -- int10--------
    rs1887111941,2
    --97523618(+) AAATTA/GTAGGG 3 -- int10--------
    rs1808281751,2
    C--97523727(+) ATTCAC/TGAAAG 3 -- int10--------
    rs77831981,2
    C,F,A,H--97523782(+) TTCTGA/TATGTG 3 -- int117Minor allele frequency- T:0.31NA NS EA WA CSA 1090
    rs1180782971,2
    F--97523846(+) TCATAC/ATCAGA 3 -- int11Minor allele frequency- A:0.03EA 120
    rs734254381,2
    C--97524095(+) TTGTCC/TGCCAT 3 -- int12Minor allele frequency- T:0.02WA 120
    rs1851855831,2
    --97524133(+) GCTTTC/TTAAAG 3 -- int10--------
    rs1437596281,2
    --97524203(+) CACAAC/TGGTTT 3 -- int10--------
    rs1908418471,2
    --97524227(+) AGCTTA/GAAACT 3 -- int10--------
    rs1817811281,2
    --97524405(+) GTTTAG/TCATTC 3 -- int10--------
    rs1875707531,2
    --97524406(+) TTTATC/TATTCT 3 -- int10--------
    rs1914000171,2
    --97524491(+) TGCCTC/TATTTG 3 -- int10--------
    rs1838164781,2
    C--97524556(+) AGATTC/GATTCA 3 -- int10--------
    rs1481263171,2
    C--97524609(+) TGTTGA/GGGAAT 6 P syn10--------
    rs2016966891,2
    --97524643(+) TAGAA-/ATGATGAA 3 -- int10--------
    rs1428543341,2
    C--97524646(+) AAATGA/GTGAAC 3 -- int10--------
    rs2010814381,2
    --97524651(+) ATGAAC/TATTTT 3 -- int10--------
    rs2009261491,2
    C--97524669(+) AACTG-/TTTGTT 3 -- int10--------
    rs1879589031,2
    --97524818(+) TAAAAA/GTTAAC 3 -- int10--------
    rs1460794811,2
    --97524857(+) ACTGCA/GGGCTA 3 -- int10--------
    rs1388211861,2
    --97524949(+) GATCCA/GGGGCC 3 -- int10--------
    rs2015232781,2
    C--97524999(+) GGCTTG/TTGCTC 3 -- int10--------
    rs1419249281,2
    --97525105(+) TCTTCA/GTGTCA 3 -- int10--------
    rs790655061,2
    C,F--97525222(+) CATTTC/TTTTTT 3 -- int11Minor allele frequency- T:0.33WA 118
    rs787426111,2
    C,F--97525228(+) TTTTTG/TTCTCA 3 -- int11Minor allele frequency- T:0.33WA 118
    rs1508046721,2
    --97525465(+) CCATCA/GAAGCC 3 -- int10--------
    rs1903467081,2
    --97525500(+) CATCAC/TTTGCA 3 -- int10--------
    rs1822041031,2
    --97525756(+) TTACAA/GTGTAA 3 -- int10--------
    rs1866596481,2
    --97525758(+) ACAATG/TTAATA 3 -- int10--------
    rs1915116361,2
    --97525767(+) TAATAG/TAAATA 3 -- int10--------
    rs745603761,2
    C--97526314(+) AATTGA/CCCCAA 3 -- int10--------
    rs1853747971,2
    --97526356(+) GTTTAG/TTATCC 3 -- int10--------
    rs1391905121,2
    C--97526779(+) CAATCG/TAAAGT 3 -- int10--------
    rs1499412671,2
    --97526867(+) TTTCAC/GTTCCA 3 -- int10--------
    rs1440443281,2
    --97526961(+) TATTCA/GTTTTT 3 -- int10--------
    rs287274781,2
    C,F--97527034(+) GTTCTT/CTCAGA 3 -- int11Minor allele frequency- C:0.04WA 118
    rs102253331,2
    C,H--97527038(+) TTTCAG/TAATTT 3 -- int14Minor allele frequency- T:0.00NS EA 418
    rs1125600121,2
    C,F--97527122(+) GTTCTG/ACATTT 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs1890883851,2
    --97527183(+) TGGGCA/TTCTCA 3 -- int10--------
    rs1928878101,2
    --97527290(+) TAGGCA/GCACAC 3 -- int10--------
    rs1854796341,2
    --97527374(+) TCTGAC/TAAAAT 3 -- int10--------
    rs1884605481,2
    --97527499(+) TCAAAA/GTCAGC 3 -- int10--------
    rs114227781,2
    C--97527526(+) GGATG-/CCCCCC 3 -- int10--------
    rs1813099611,2
    --97527549(+) TGGCCC/TTCCCA 3 -- int10--------
    rs1840570591,2
    --97527600(+) AAAGTC/GAACCT 3 -- int10--------
    rs1443258021,2
    --97527634(+) CCTCCA/GTTTTT 3 -- int10--------
    rs1477910781,2
    --97527673(+) TAAATC/TACAAT 3 -- int10--------
    rs1411562131,2
    --97527781(+) TCTTAC/TATTGA 3 -- int10--------
    rs784152151,2
    F--97527808(+) TATCCA/CTAGTG 3 -- int11Minor allele frequency- C:0.01NA 120
    rs1880530711,2
    --97527874(+) GGAAAC/TTTAGA 3 -- int10--------
    rs1809209611,2
    --97527954(+) CCCTGA/CTTGGG 3 -- int10--------
    rs1450109381,2
    --97528179(+) AAATGC/TCTTCA 3 -- int10--------
    rs1871473411,2
    --97528284(+) GGAGCA/GGGGGG 3 -- int10--------
    rs1924928991,2
    --97528289(+) GGGGGA/GTCGAC 3 -- int10--------
    rs1816248691,2
    --97528309(+) AGGCCC/GTATAA 3 -- int10--------
    rs1871025471,2
    --97528596(+) ATTTCA/TTATGT 3 -- int10--------
    rs1906965951,2
    --97528648(+) ATACCA/GTAATT 3 -- int10--------
    rs1825741131,2
    --97529010(+) TCATTC/GTGACC 3 -- int10--------
    rs745525841,2
    F--97529013(+) TTGTGA/GCCAAA 3 -- int11Minor allele frequency- G:0.01WA 118
    rs1513369111,2
    --97529044(+) ATTTAA/CATAAA 3 -- int10--------
    rs1871816901,2
    --97529206(+) GAAAAG/TTTTTG 3 -- int10--------
    rs10007141,2
    C,F,H--97529316(-) TACCAA/GTTGAT 3 -- int19Minor allele frequency- G:0.15NA NS EA 821
    rs1896844471,2
    --97529378(+) GACAGC/TATACC 3 -- int10--------
    rs1406026951,2
    --97529594(+) GAAGAC/GTCTAG 3 -- int10--------
    rs1504700241,2
    --97529677(+) TTCACA/GTGGGG 3 -- int10--------
    rs1830149131,2
    --97529735(+) GTGAAC/TAACAA 3 -- int10--------
    rs1887667871,2
    --97529858(+) ACATAC/GACTTC 3 -- int10--------
    rs104999051,2
    C,F,H--97529972(+) CTTGAC/TGTTCC 3 -- int188Minor allele frequency- T:0.12NS EA PA EU CA WA NA 4600
    rs2000237641,2
    C--97530033(+) TAATT-/AGAA  
            
    AGGGC
    3 -- int10--------
    rs1932815041,2
    --97530052(+) TTGAGA/GTACAC 3 -- int10--------
    rs1169935101,2
    C,F--97530059(+) ACACCG/AGTCAA 3 -- int11Minor allele frequency- A:0.02NA 120
    rs102670271,2
    C,F,H--97530207(+) AGACAA/GATGTC 3 -- int15Minor allele frequency- G:0.02NS EA WA 536
    rs1833664421,2
    --97530255(+) ACTTAC/TTCACT 3 -- int10--------
    rs1143336871,2
    C,F--97530438(+) TGTGTC/TCTAGA 3 -- int11Minor allele frequency- T:0.04WA 118
    rs1872649621,2
    --97530483(+) AAAACA/GAATGA 3 -- int10--------
    rs1382764171,2
    --97530529(+) AGTACC/TGAAAC 3 -- int10--------
    rs1413316781,2
    --97530530(+) GTACCA/GAAACT 3 -- int10--------
    rs1180104121,2
    C,F--97530585(+) AACAAC/TGGGAG 3 -- int11Minor allele frequency- T:0.01NA 120
    rs1922005971,2
    --97530633(+) TTTGTA/GACTTT 3 -- int10--------
    rs1149024211,2
    C,F--97530924(+) ATGACC/TGACAC 3 -- int11Minor allele frequency- T:0.01WA 118
    rs1838174961,2
    --97530925(+) TGACCA/GACACT 3 -- int10--------
    rs1885894971,2
    --97530950(+) AGATAC/TCAGGA 3 -- int10--------
    rs1450659801,2
    --97531047(+) CATTTA/TTTCTT 3 -- int10--------
    rs1922959501,2
    --97531139(+) TGGCAG/TCCATT 3 -- int10--------
    rs676820531,2
    C,F--97531443(+) ACAAGA/GCAGCA 3 -- int15Minor allele frequency- G:0.16NA WA EA 362
    rs102606421,2
    C,F,H--97531460(+) AAGCAT/CATACC 3 -- int114Minor allele frequency- C:0.05NS EA NA 1664
    rs1143872101,2
    F--97531506(+) ATATCA/GCATTT 3 -- int11Minor allele frequency- G:0.04WA 118
    rs1419850111,2
    C--97531616(+) AAAAGC/TAAAAG 3 -- int10--------
    rs1845844811,2
    --97531634(+) TGCATA/GAAGGA 3 -- int10--------
    rs1446729751,2
    --97531667(+) ATAAAC/TTCCCT 3 -- int10--------
    rs1165657041,2
    F--97531932(+) TTAATG/AGAGCT 3 -- int11Minor allele frequency- A:0.01WA 118
    rs1903116761,2
    --97531943(+) TTTCCA/GTTAGC 3 -- int10--------
    rs1822391881,2
    --97531963(+) AATAAG/TGTGAA 3 -- int10--------
    rs766153911,2
    C,F--97532147(+) TGTATA/GTTAGT 3 -- int11Minor allele frequency- G:0.32EA 120
    rs1480722401,2
    --97532418(+) TTGAAA/GAGTTA 3 -- int10--------
    rs1865043861,2
    --97532597(+) AAAGGC/GCATGC 3 -- int10--------
    rs1417933101,2
    --97532659(+) ATTTGA/GTTAGC 3 -- int10--------
    rs1888842571,2
    --97532670(+) TACAGA/GATTTG 3 -- int10--------
    rs171663751,2
    C,F,H--97532707(+) CTACTA/GCTTTT 3 -- int114Minor allele frequency- G:0.08NA EA NS WA 1284
    rs1505804011,2
    --97532898(+) TAAATG/TCTGAA 3 -- int10--------
    rs732221261,2
    C--97532947(+) TCAGTA/GTCTAA 3 -- int10--------
    rs1856641611,2
    --97533082(+) ATATAC/TTAATG 3 -- int10--------
    rs1147466181,2
    F--97533261(+) TTTCTG/TAAGTA 3 -- int11Minor allele frequency- T:0.03WA 118
    rs1153081621,2
    F--97533307(+) TATATT/GAATTA 3 -- int11Minor allele frequency- G:0.01WA 118
    rs1916167691,2
    --97533369(+) ACTCAA/GTGGGA 3 -- int10--------
    rs734254411,2
    C,F--97533407(+) AAATGT/CGTTCA 3 -- int13Minor allele frequency- C:0.23WA 122
    rs1824915991,2
    --97533469(+) AGAGAA/GAGAGA 3 -- int10--------
    rs1148443521,2
    F--97533545(+) AAGAGG/AAGGAC 3 -- int11Minor allele frequency- A:0.02WA 118
    rs1862220451,2
    --97533550(+) GAGGAC/TCTCAA 3 -- int10--------
    rs1405318981,2
    --97533562(+) AGCCAA/GCTTCA 3 -- int10--------
    rs1908441991,2
    --97533634(+) AAGGCC/TGGGCA 3 -- int10--------
    rs3675675011,2
    C--97533842(+) GGAGGC/TGAGGC 4 P syn1 int10--------
    rs1839517301,2
    C--97533865(+) AAGATC/TGCTCC 4 N D mis1 int10--------
    rs102475621,2
    C,F,A,H--97533868(+) ATCGCG/TCCATT 4 S R mis1 int16Minor allele frequency- T:0.27NA WA CSA 11
    rs1877794411,2
    --97533909(+) TCCATC/GTTAAA 3 -- spa1 int10--------
    rs102323981,2
    C,F,A,H--97534101(+) CCCTTA/GTCTAC 3 -- int130Minor allele frequency- G:0.21NS EA NA WA CSA 2749
    rs1919248001,2
    --97534151(+) TATAGC/TACTAG 3 -- int10--------
    rs1479407281,2
    C--97534343(+) AAAAT-/AATC  
            
    AATTT
    3 -- int10--------
    rs412788031,2
    C,F--97534407(+) AAACAT/CGTAAT 3 -- int15Minor allele frequency- C:0.20NA EA 246
    rs1161581451,2
    C,F--97534438(+) CAATTT/CCTTAA 3 -- int11Minor allele frequency- C:0.04WA 118
    rs1473877401,2
    C--97534695(+) CATCAA/GTGGCA 6 L syn10--------
    rs2000209221,2
    --97534754(+) CAGTCA/GCAGGG 6 A V mis10--------
    rs1390623601,2
    C--97534860(+) GACCAG/ATTGGA 6 /L syn11Minor allele frequency- A:0.00NA 4550
    rs1181765661,2
    C,F--97534909(+) ATCATA/GTATTA 3 -- int12Minor allele frequency- G:0.00NA EU 711
    rs1830413811,2
    --97535069(+) CTGATC/TTTAAA 3 -- int10--------
    rs1395491721,2
    --97535141(+) AACCAA/CCTAGT 3 -- int10--------
    rs1869192861,2
    --97535610(+) GTGTTC/TGCATG 5 Q R mis1 int10--------
    rs284392811,2
    C,F--97535863(+) TCAAGG/ACCTTG 3 -- int13Minor allele frequency- A:0.09WA NA EA 358
    rs286141631,2
    C,F--97535872(+) TGATTG/AAAATA 3 -- int13Minor allele frequency- A:0.09WA NA EA 358
    rs1142855341,2
    F--97535884(+) ATTCTA/GTGACA 3 -- int11Minor allele frequency- G:0.01WA 118
    rs1929751901,2
    --97535988(+) TAATCC/TTGGGA 3 -- int10--------
    rs1498911721,2
    C--97536115(+) ATATTG/TTAAAC 3 -- int10--------
    rs13573161,2
    O,H--97536161(+) TTTCAA/TGAGTT 3 -- int18Minor allele frequency- T:0.00NA EA NS 758
    rs607473291,2
    C,F--97536217(+) ATTACC/TATGTC 3 -- int13Minor allele frequency- T:0.04WA CSA 122
    rs1848292911,2
    --97536330(+) GCCTTA/GATAAT 3 -- int10--------
    rs1450400651,2
    C,F--97536612(+) ACTGCC/TGAGGG 6 S syn12Minor allele frequency- T:0.00NA EU 5851
    rs115482861,2
    H--97536688(-) TGGAGA/CATACA 6 E A mis1 ese34Minor allele frequency- C:0.00NS EA 406
    rs2012345611,2
    --97536732(+) TCCTGA/GTAGGT 6 Y syn10--------
    rs2004006811,2
    --97536745(+) ACACTC/TGCTTT 6 Q R mis10--------
    rs2009566011,2
    --97536843(+) AAGCA-/TTCTTT 3 -- int10--------
    rs1448955211,2
    --97536979(+) TGTTCG/TTCCTA 3 -- int10--------
    rs1145417941,2
    C--97537026(+) TTAACA/GTGTGT 3 -- int10--------
    rs1893434761,2
    C--97537040(+) TATACA/GTGTAG 3 -- int10--------
    rs1923323071,2
    --97537137(+) TGCAGA/GTTTTA 3 -- int10--------
    rs1847504471,2
    --97537177(+) ATGCAC/TGTATG 3 -- int10--------
    rs21771781,2
    C,H--97537187(+) GGTTTC/TTAAGT 3 -- int14Minor allele frequency- T:0.00EA NS NA 300
    rs1429830541,2
    --97537225(+) AGAGGA/GACAAT 3 -- int10--------
    rs174790861,2
    C,F--97537227(+) AGGGAC/GAATTT 3 -- int17Minor allele frequency- G:0.26NA WA EA 502
    rs2008828451,2
    C--97537348(+) GTATC-/AAAAAAAA
    AAAAAAAAAAA
    AAAAA
    3 -- int10--------
    rs1896184191,2
    --97537388(+) ACAACA/GGTTGC 3 -- int10--------
    rs1815928011,2
    --97537459(+) CTAAGA/GTTTTT 3 -- int10--------
    rs1511087411,2
    --97537472(+) TGAAGA/GACACT 3 -- int10--------
    rs1862079221,2
    --97537512(+) ACATTG/TGCTAC 3 -- int10--------
    rs745987801,2
    --97537669(+) TGAGAA/CCTAAA 3 -- int10--------
    rs1450988131,2
    C--97537675(+) CTAAAC/TATGAA 3 -- int10--------
    rs1389021371,2
    --97537740(+) GCTTAG/TTTTTG 3 -- int10--------
    rs1406076091,2
    --97537838(+) TCTTTC/TGTGGC 3 -- int10--------
    rs1504189501,2
    --97538012(+) CAACCA/GCAAGT 3 -- int10--------
    rs1895085771,2
    --97538068(+) AGGAAC/TCTAAG 3 -- int10--------
    rs1381585291,2
    --97538113(+) GTATCA/GTTAGC 3 -- int10--------
    rs1495559671,2
    --97538135(+) ACAAAC/TTTTCC 3 -- int10--------
    rs1811510721,2
    --97538141(+) TTTCCA/TATAAT 3 -- int10--------
    rs171663761,2
    C,F,H--97538241(+) TGAGAA/CGGAGA 3 -- int1 trp318Minor allele frequency- C:0.25NA NS EA WA CSA 1736
    rs1864679431,2
    --97538330(+) AAGACA/GTGAAG 3 -- int10--------
    rs1908591441,2
    --97538453(+) ACTAAA/GTAATT 3 -- int10--------
    rs2021964481,2
    --97538562(+) CAGAC-/ATATA 
            
    ATATA
    3 -- int10--------
    rs1432016351,2
    C--97538683(+) ATATTA/GTGTTT 3 -- int10--------
    rs1822379621,2
    --97539120(+) GCAGTA/TCAGGT 3 -- int10--------
    rs1862282691,2
    C--97539137(+) CAAACA/GTTAAC 3 -- int10--------
    rs1998715081,2
    C--97539232(+) AGTACG/AAAATT 6 /R /C mis11Minor allele frequency- A:0.00EU 1265
    rs1161052641,2
    C,F--97539250(+) ACATGT/GTATTA 6 /T /P mis11Minor allele frequency- G:0.00NA 4502
    rs1428331061,2
    C--97539303(+) TTTCAA/GCTTCT 6 A V mis10--------
    rs2011586581,2
    --97539330(+) ACGGGA/GCATCT 6 A V mis10--------
    rs1909930401,2
    --97539439(+) ATTTAC/GCCTTT 3 -- int10--------
    rs1474044131,2
    --97539453(+) ATTGAC/GAGATT 3 -- int10--------
    rs1828273651,2
    --97539555(+) ATTTAC/TTGAGT 3 -- int10--------
    rs1872478331,2
    --97539579(+) AGATAA/CTCTCT 3 -- int10--------
    rs2002242551,2
    C--97539668(+) TACTA-/TATT  
            
    TAGTA
    3 -- int10--------
    rs779211801,2
    F--97539676(+) TTAGTA/TATTAC 3 -- int12Minor allele frequency- T:0.33CSA WA 119
    rs1916650871,2
    --97539761(+) AAATAA/GCTAAG 3 -- int10--------
    rs1396180841,2
    --97539807(+) TTTAAA/GTTACA 3 -- int10--------
    rs102568851,2
    C,F,H--97539882(+) TACTAC/TACAAA 3 -- int16Minor allele frequency- T:0.00NS EA NA 422
    rs1158915791,2
    F--97539897(+) TATATG/TCTTGG 3 -- int11Minor allele frequency- T:0.04WA 118
    rs1505268291,2
    --97540024(+) GGGAAA/GGATCT 3 -- int10--------
    rs102727571,2
    C,F,H--97540027(+) AAAGAT/GCTCTA 3 -- int15Minor allele frequency- G:0.02NS EA WA 536
    rs1830739141,2
    --97540200(+) CTAGGA/GAAAAA 3 -- int10--------
    rs1880193331,2
    --97540226(+) GAAGTA/CAAACC 3 -- int10--------
    rs1394740671,2
    --97540256(+) TCTTTA/GCAGAA 3 -- int10--------
    rs1397969781,2
    C--97540317(+) GCCAT-/ACAC  
            
    ACACA
    3 -- int10--------
    rs1926836081,2
    --97540406(+) AGCTAC/TAGTAA 3 -- int10--------
    rs1496607921,2
    --97540587(+) TCCACA/GTATCC 3 -- int10--------
    rs1839602761,2
    --97540597(+) CTGTCC/GTACCT 3 -- int10--------
    rs1926286601,2
    --97540778(+) ATCCCA/GTCCTA 3 -- int10--------
    rs102316561,2
    C,F,H--97540952(+) acattA/Ggtcca 3 -- int120Minor allele frequency- G:0.20NS EA NA WA CSA 2336
    rs1401751791,2
    --97541033(+) CACACC/TGGAAT 3 -- int10--------
    rs1849745301,2
    --97541185(+) TAAGTC/GAGAAA 3 -- int10--------
    rs732221341,2
    C,F--97541285(+) CTTGTT/CTAAAA 3 -- int12Minor allele frequency- C:0.08NA EA 240
    rs1901339171,2
    --97541424(+) ATTTTA/GTCATA 3 -- int10--------
    rs69798911,2
    C,A--97541655(+) ggcaaC/Aaaaca 3 -- int14Minor allele frequency- A:0.16NA WA EA 360
    rs1438457551,2
    --97541677(+) CAAATA/GTAGTA 3 -- int10--------
    rs1817422041,2
    --97541735(+) GTCTCA/GCCCTG 3 -- int10--------
    rs1847301441,2
    C--97541845(+) GTGCCC/TGCCAC 3 -- int10--------
    rs69802291,2
    C--97541857(+) acaccG/Cagcta 3 -- int11Minor allele frequency- C:0.50NA 2
    rs1489725931,2
    --97541977(+) CAGGCA/GTGAGC 3 -- int10--------
    rs1437225881,2
    --97542014(+) TTAAAC/TATCAA 3 -- int10--------
    rs1510579961,2
    --97542019(+) CATCAA/GTGGTC 3 -- int10--------
    rs1897626461,2
    C--97542321(+) TGCCTC/TATAAC 3 -- int10--------
    rs1501907041,2
    --97542489(+) TCAGTC/TGACAG 3 -- int10--------
    rs1808334951,2
    --97542566(+) GAAACA/TTTTAG 3 -- int10--------
    rs1851994261,2
    --97542570(+) CATTTA/GGCAAC 3 -- int10--------
    rs675569251,2
    C,F--97542704(+) TAGGAA/GACTAA 3 -- int16Minor allele frequency- G:0.16NA CSA WA EA 364
    rs74591231,2
    H--97543166(+) cattcT/Catgaa 3 -- int14Minor allele frequency- C:0.00NS EA 418
    rs1897622611,2
    --97543317(+) GAATTA/GTACAC 3 -- int10--------
    rs69437821,2
    C,F,A,H--97543430(+) catcaG/Tcagat 3 -- int111Minor allele frequency- T:0.18NA WA CSA EA 371
    rs2007621451,2
    --97543474(+) TTGTG-/AAAAAA 3 -- int10--------
    rs1817842161,2
    --97543512(+) GGGGAA/GTTTCC 3 -- int10--------
    rs1389785551,2
    --97543530(+) GATACC/TTACAG 3 -- int10--------
    rs1871895791,2
    --97543572(+) TTTCCC/TACTAG 3 -- int10--------
    rs1428968271,2
    --97544208(+) AAAATA/CCTTAA 3 -- int10--------
    rs69628661,2
    C,F--97544233(+) ctaatG/Aaaata 3 -- int14Minor allele frequency- A:0.42WA CSA 124
    rs1916666201,2
    --97544582(+) TGGGAA/TATAAT 3 -- int10--------
    rs768759111,2
    C--97544619(+) TACACA/GTTTAG 3 -- int10--------
    rs1495025281,2
    --97544822(+) AAACTA/CTGAAA 3 -- int10--------
    rs1835919601,2
    --97545065(+) AAAAAA/CCACTT 3 -- int10--------
    rs1882456371,2
    C--97545149(+) CAGCAC/GTTTTG 3 -- int10--------
    rs1903591451,2
    --97545330(+) AGGAGA/GCAGAG 3 -- int10--------
    rs1486332051,2
    --97545483(+) TGAAAA/CGATGC 3 -- int10--------
    rs561838931,2
    C,F--97545540(+) ACGCAA/GCACAC 3 -- int14Minor allele frequency- G:0.20NA EA 244
    rs1411709301,2
    --97545678(+) TTCTTA/GCAAAA 3 -- int10--------
    rs1126446801,2
    C--97545836(+) CTCCAG/ATAGGT 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs1165665531,2
    F--97545877(+) AAATGG/CAATAT 3 -- int11Minor allele frequency- C:0.03WA 118
    rs1822429751,2
    --97545878(+) AATGGA/CATATT 3 -- int10--------
    rs1866598981,2
    --97546126(+) CTACTA/CTGTAT 3 -- int10--------
    rs1915157431,2
    --97546382(+) GTATAC/TGCACA 3 -- int10--------
    rs734254471,2
    C,F--97546969(+) AAAATG/ATTAAA 3 -- int12Minor allele frequency- A:0.10WA 120
    rs1120078611,2
    C,F--97547037(+) GAAAAC/TATATG 3 -- int11Minor allele frequency- T:0.50CSA 2
    rs1461813431,2
    --97547155(+) CATATA/CCATAA 3 -- int10--------
    rs1888256551,2
    C--97547163(+) TAAAAC/TAGAAT 3 -- int10--------
    rs47291411,2
    H--97547403(+) tgtggT/Agttgg 3 -- int14Minor allele frequency- A:0.00NS EA 418
    rs1931046701,2
    --97547552(+) TTTTTA/TAAATG 3 -- int10--------
    rs1853628661,2
    --97547571(+) TAAAAA/GTACAG 3 -- int10--------
    rs1897753111,2
    --97547584(+) CAAAAA/GTTCAA 3 -- int10--------
    rs734254481,2
    C--97547645(+) GTGTTC/TGAGAA 3 -- int12Minor allele frequency- T:0.13WA 120
    rs1810677321,2
    --97547737(+) AACCTA/GTTGTA 3 -- int10--------
    rs732221391,2
    C--97547743(+) TTGTAC/GCTTTG 3 -- int10--------
    rs1879557561,2
    --97547931(+) CAAGGC/TAACAC 3 -- int10--------
    rs1390434441,2
    --97547997(+) TGTTTC/GTTACA 3 -- int10--------
    rs1139373111,2
    C--97548151(+) CCAGTG/ATAAAA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1808722641,2
    --97548547(+) ATGACA/GGTTGA 3 -- int10--------
    rs1873474951,2
    --97548906(+) TGCTCC/TTTGAA 3 -- int10--------
    rs19159891,2
    C,F,A,H--97549104(-) GCCAGT/CGTGTT 3 -- int113Minor allele frequency- C:0.17NA EA NS WA 1022
    rs283802301,2
    C--97549106(+) CACACT/AGGCTT 3 -- int14Minor allele frequency- A:0.09NA WA EA 360
    rs1155463651,2
    C--97549121(+) AAATAC/TGTAAT 3 -- int10--------
    rs19159881,2
    C,F,H--97549140(-) ACACAT/CGGACT 3 -- int112Minor allele frequency- C:0.16NS EA NA WA 958
    rs1468702611,2
    --97549285(+) ACATGA/TTTTCA 3 -- int10--------
    rs1921176911,2
    --97549301(+) CAAATA/GTGTAT 3 -- int10--------
    rs1488407341,2
    C--97549368(+) AACCT-/GGGTAC 3 -- int10--------
    rs1140729211,2
    C,F--97549396(+) TGGAGT/CGCACT 3 -- int11Minor allele frequency- C:0.04WA 118
    rs1393743611,2
    C--97549437(+) TTTATA/CCCAAC 3 -- int10--------
    rs1817362531,2
    --97549486(+) GAGGCA/CTTTAC 3 -- int10--------
    rs341737371,2
    C,F--97549491(+) CTTTAC/GATTTA 3 -- int16Minor allele frequency- G:0.16NA WA EA 364
    rs1500325481,2
    --97549774(+) TACCTC/GCAATT 3 -- int10--------
    rs1452837321,2
    C--97549787(+) TCAATA/CAAAAA 3 -- int10--------
    rs121138051,2
    C,A--97549975(+) GAAATC/AAAAAA 3 -- int11Minor allele frequency- A:0.50WA 2
    rs1869179941,2
    --97549992(+) AAAAAA/CAAAAA 3 -- int10--------
    rs788422131,2
    C--97550031(+) TAGAGA/TGGGGA 3 -- int10--------
    rs1491642661,2
    C--97550091(+) TAAAAG/TAATTT 3 -- int10--------
    rs1464679341,2
    --97550182(+) CACCTA/GTATCC 3 -- int10--------
    rs793637991,2
    C--97550372(+) CTCCAC/TTTCCA 3 -- int10--------
    rs798540281,2
    C,F--97550420(+) ACCTTC/TGGTAC 3 -- int12Minor allele frequency- T:0.32CSA WA 120
    rs1142670041,2
    F--97550426(+) GGTACT/CCGCCC 3 -- int11Minor allele frequency- C:0.04WA 118
    rs1135854061,2
    F--97550598(+) ACTTAG/AAACAC 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs132457741,2
    H--97550673(+)