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SFXN3 Gene

protein-coding   GIFtS: 51
GCID: GC10P102781

Sideroflexin 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Sideroflexin 31 2
BA108L7.22
SFX32
sideroflexin-32

External Ids:    HGNC: 160871   Entrez Gene: 818552   Ensembl: ENSG000001078197   OMIM: 6155715   UniProtKB: Q9BWM73   

Export aliases for SFXN3 gene to outside databases

Previous GC identifers: GC00U991057 GC10P096420


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SFXN3 Gene:
SFXN3 (sideroflexin 3) is a protein-coding gene. Diseases associated with SFXN3 include cystic fibrosis, and neuroblastoma. GO annotations related to this gene include cation transmembrane transporter activity. An important paralog of this gene is SFXN4.

UniProtKB/Swiss-Prot: SFXN3_HUMAN, Q9BWM7
Function: Potential iron transporter




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SFXN3 gene promoter:
         Bach1   RFX1   CUTL1   C/EBPalpha   GATA-1   AREB6   PPAR-alpha   PPAR-gamma1   c-Rel   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSFXN3 promoter sequence
   Search Chromatin IP Primers for SFXN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SFXN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.31   Ensembl cytogenetic band:  10q24.31   HGNC cytogenetic band: 10q24.32

SFXN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SFXN3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P102781:  view genomic region     (about GC identifiers)

Start:
102,790,991 bp from pter      End:
102,800,998 bp from pter
Size:
10,008 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SFXN3_HUMAN, Q9BWM7 (See protein sequence)
Recommended Name: Sideroflexin-3  
Size: 325 amino acids; 35979 Da
Caution: It is uncertain whether Met-1 or Met-5 is the initiator
Secondary accessions: Q8NCJ0 Q9NTP4

Explore the universe of human proteins at neXtProt for SFXN3: NX_Q9BWM7

Explore proteomics data for SFXN3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys75, Lys173
  • Modification sites at PhosphoSitePlus

  • See SFXN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112233.2  
    ENSEMBL proteins: 
     ENSP00000377103   ENSP00000474564   ENSP00000224807  

    SFXN3 Human Recombinant Protein Products:

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    Novus Biologicals SFXN3 Proteins
    Novus Biologicals SFXN3 Lysates
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    Cloud-Clone Corp. Proteins for SFXN3

    SFXN3 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for SFXN3

    SFXN3 Assay Products:

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    Cloud-Clone Corp. ELISAs for SFXN3
    Cloud-Clone Corp. CLIAs for SFXN3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SFXN: Sideroflexins

    1 InterPro protein domain:
     IPR004686 Mtc

    Graphical View of Domain Structure for InterPro Entry Q9BWM7

    ProtoNet protein and cluster: Q9BWM7

    1 Blocks protein domain: IPB004686 Tricarboxylate/iron carrier

    UniProtKB/Swiss-Prot: SFXN3_HUMAN, Q9BWM7
    Similarity: Belongs to the sideroflexin family


    SFXN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SFXN3_HUMAN, Q9BWM7
    Function: Potential iron transporter

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008324cation transmembrane transporter activity IEA--
         
    SFXN3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for SFXN3:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Sfxn3):
     no phenotypic analysis 

    SFXN3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Sfxn3tm1Mdf for SFXN3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SFXN3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SFXN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SFXN3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SFXN3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat SFXN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SFXN3 (see all 11):
    hsa-miR-4324 hsa-miR-4283 hsa-miR-3194-5p hsa-miR-15a hsa-miR-3924 hsa-miR-497 hsa-miR-424 hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidSFXN3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SFXN3
    Predesigned siRNA for gene silencing in human, mouse, rat SFXN3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SFXN3

    Clone
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    OriGene clones in human, mouse for SFXN3 (see all 7)
    OriGene ORF clones in mouse, rat for SFXN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SFXN3 (NM_030971)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SFXN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFXN3

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFXN3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SFXN3_HUMAN, Q9BWM7: Mitochondrion membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    peroxisome2
    nucleus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0031966mitochondrial membrane IEA--

    SFXN3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SFXN3 About    
    See pathways by source

    SuperPathContained pathways About
    1Validated targets of C-MYC transcriptional repression
    Validated targets of C-MYC transcriptional repression


    1 BioSystems Pathway for SFXN3
        Validated targets of C-MYC transcriptional repression


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SFXN3
    Interactions:

        Search GeneGlobe Interaction Network for SFXN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SFXN3 (Q9BWM73 ENSP000002248074) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CFTRP135693I2D: score=1 
    CLN3Q132863I2D: score=1 
    DLG4P783523I2D: score=1 
    GRID2O434243I2D: score=1 
    SLC2A4P146723I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0055072iron ion homeostasis IEA--
    GO:0055085transmembrane transport ----

    SFXN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SFXN3

    1 HMDB Compound for SFXN3    About this table
    CompoundSynonyms CAS #PubMed Ids
    IronArmco iron (see all 19)7439-89-6--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SFXN3 gene: 
    NM_030971.3  

    Unigene Cluster for SFXN3:

    Sideroflexin 3
    Hs.283844  [show with all ESTs]
    Unigene Representative Sequence: AK091504
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000393459(uc001ksp.3 uc010qpx.2) ENST00000489434 ENST00000465383
    ENST00000487721 ENST00000466982 ENST00000470252 ENST00000224807
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SFXN3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SFXN3 (see all 11):
    hsa-miR-4324 hsa-miR-4283 hsa-miR-3194-5p hsa-miR-15a hsa-miR-3924 hsa-miR-497 hsa-miR-424 hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidSFXN3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SFXN3
    Predesigned siRNA for gene silencing in human, mouse, rat SFXN3
    Clone
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    OriGene clones in human, mouse for SFXN3 (see all 7)
    OriGene ORF clones in mouse, rat for SFXN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SFXN3 (NM_030971)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SFXN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFXN3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SFXN3
    OriGene qSTAR qPCR primer pairs in human, mouse for SFXN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SFXN3
      QuantiTect SYBR Green Assays in human, mouse, rat SFXN3
      QuantiFast Probe-based Assays in human, mouse, rat SFXN3

    Additional mRNA sequence: 

    AK074707.1 AK091504.1 AK093011.1 AK299405.1 BC000124.1 

    13 DOTS entries:

    DT.100732820  DT.117566  DT.40114554  DT.121238733  DT.40244331  DT.99953089  DT.100716642  DT.121238784 
    DT.100781687  DT.121238778  DT.121238788  DT.95363720  DT.92447174 

    Selected AceView cDNA sequences (see all 162):

    BI908654 T30448 F01846 BU184941 F04451 CD370488 CA488624 T31239 
    CR614959 T30958 BQ223306 BG254227 CF125913 F08208 BQ876481 BM772320 
    BM451364 BC000124 BU617280 BQ887722 NM_030971 BQ959114 AA293453 AI732397 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SFXN3 (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14
    SP1:                                                  -                       -                                                     -                     
    SP2:                    -                             -                       -                                                                           
    SP3:                                                  -           -     -     -                                                                           
    SP4:                                                  -                 -     -                                                                           
    SP5:                    -                             -                 -     -                                                                           


    ECgene alternative splicing isoforms for SFXN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SFXN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTCTGGCT
    SFXN3 Expression
    About this image

    SFXN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SFXN3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.283844
        Custom PCR Arrays for SFXN3
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    QuantiFast Probe-based Assays in human, mouse, rat SFXN3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFXN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SFXN3 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sfxn31 , 5 sideroflexin 31, 5 88.47(n)1
    93.77(a)1
      19 (38.26 cM)5
    942801  NM_053197.41  NP_444427.11 
     450475765 
    chicken
    (Gallus gallus)
    Aves SFXN36
    sideroflexin 3
    76(a)
    1 ↔ 1
    6(22606961-22610615)
    lizard
    (Anolis carolinensis)
    Reptilia SFXN36
    sideroflexin 3
    78(a)
    1 ↔ 1
    GL343239.1(208246-230875)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sfxn31 sideroflexin 3 70.53(n)
    77.74(a)
      100216274  NM_001142227.1  NP_001135699.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sfxn31 sideroflexin 3 70.62(n)
    76.25(a)
      791182  NM_001080664.1  NP_001074133.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG117396
    --
    54(a)
    1 → many
    3R(204386-206932)
    worm
    (Caenorhabditis elegans)
    Secernentea sfxn-1.41 sfxn-1.4 55.35(n)
    54.4(a)
      183547  NM_001267379.1  NP_001254308.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes FSF16
    Putative protein, predicted to be an alpha-isoprop...
    38(a)
    1 → many
    XV(831059-832042) YOR271C


    ENSEMBL Gene Tree for SFXN3 (if available)
    TreeFam Gene Tree for SFXN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SFXN3 gene
    SFXN42  SFXN12  SFXN52  SFXN22  
    3 SIMAP similar genes for SFXN3 using alignment to 2 protein entries:     SFXN3_HUMAN (see all proteins):
    SFXN1    SFXN2    SFXN5

    SFXN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SFXN3 (see all 192)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs118122361,2
    C,F,H--102793044(+) GTGTGT/CAATAT 1 -- int113Minor allele frequency- C:0.03NS EA NA WA CSA 1214
    rs1427988561,2
    --102793089(+) GTGGCC/TGGGAT 1 -- int10--------
    rs578479801,2
    --102793321(+) CTGTGC/GGTATT 1 -- int10--------
    rs1825671451,2
    --102793322(+) TGTGGA/GTATTT 1 -- int10--------
    rs1408929741,2
    --102793371(+) ACACAG/TAGACA 1 -- int10--------
    rs1433488421,2
    --102793410(+) GGGACC/TGGCGT 1 -- int10--------
    rs1853359641,2
    --102793413(+) ACCGGA/CGTTCA 1 -- int10--------
    rs1124182621,2
    C--102793439(+) GCACCA/GGCACC 1 -- int10--------
    rs8070501,2
    C,F,A,H--102793508(-) actacT/Gacatt 1 -- int124Minor allele frequency- G:0.28NS EA NA WA CSA 2533
    rs1908727131,2
    --102793538(+) GAGAAG/TGTCAG 1 -- int10--------

    HapMap Linkage Disequilibrium report for SFXN3 (102790991 - 102800998 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SFXN3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7525CNV Insertion18451855
    nsv895963CNV Loss21882294
    nsv831965CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SFXN3
    DNA2.0 Custom Variant and Variant Library Synthesis for SFXN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615571    OMIM disorders: --

    2 diseases for SFXN3:    
    About MalaCards
    cystic fibrosis    neuroblastoma


    SFXN3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SFXN3
    Human Genome Epidemiology (HuGE) Navigator: SFXN3 (1 document)

    Export disorders for SFXN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SFXN3 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SFXN3)
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    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. (PubMed id 23464991)1 Scifo E....Lalowski M. (J. Proteome Res. 2013)
    4. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    9. Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. (PubMed id 18854154)1 KAPnig R....Chanda S.K. (Cell 2008)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81855 HGNC: 16087 AceView: BA108L7.2 Ensembl:ENSG00000107819 euGenes: HUgn81855
    ECgene: SFXN3 H-InvDB: SFXN3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SFXN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SFXN3 gene:
    Search GeneIP for patents involving SFXN3

    GeneCards and IP:
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