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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SFXN1 Gene

protein-coding   GIFtS: 55
GCID: GC05P174838

Sideroflexin 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Sideroflexin 11 2
Tricarboxylate Carrier Protein2 3
TCC2 3
sideroflexin-12

External Ids:    HGNC: 160851   Entrez Gene: 940812   Ensembl: ENSG000001644667   UniProtKB: Q9H9B43   

Export aliases for SFXN1 gene to outside databases

Previous GC identifers: GC05U990169 GC05P175644 GC05P174840 GC05P174886 GC05P170004


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SFXN1 Gene: 
SFXN1 (sideroflexin 1) is a protein-coding gene. Diseases associated with SFXN1 include neonatal anemia, and aceruloplasminemia. GO annotations related to this gene include cation transmembrane transporter activity. An important paralog of this gene is SFXN4.

UniProtKB/Swiss-Prot: SFXN1_HUMAN, Q9H9B4
Function: Might be involved in the transport of a component required for iron utilization into or out of the
mitochondria

Gene Wiki entry for SFXN1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_023133.13  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SFXN1 gene promoter:
         TBP   GCNF   E4BP4   HNF-1A   AREB6   PPAR-gamma1   GCNF-1   TFIID   PPAR-gamma2   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSFXN1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SFXN1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SFXN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  5q35.2   HGNC cytogenetic band: 5q35.3

SFXN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SFXN1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P174838:  view genomic region     (about GC identifiers)

Start:
174,904,065 bp from pter      End:
174,956,745 bp from pter
Size:
52,681 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SFXN1_HUMAN, Q9H9B4 (See protein sequence)
Recommended Name: Sideroflexin-1  
Size: 322 amino acids; 35619 Da
Subcellular location: Mitochondrion membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=AAH20517.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB14003.1; Type=Miscellaneous discrepancy; Note=Cloning artifact; Sequence=BAB14318.1; Type=Erroneous
initiation; Note=Translation N-terminally extended;
Secondary accessions: B3KPW3 D3DQN2 Q9HA53

Explore the universe of human proteins at neXtProt for SFXN1: NX_Q9H9B4

Explore proteomics data for SFXN1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H9B4

  • SFXN1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SFXN1 Protein Expression
    REFSEQ proteins: NP_073591.2  
    ENSEMBL proteins: 
     ENSP00000420961   ENSP00000316905   ENSP00000473710   ENSP00000421982   ENSP00000421467  
     ENSP00000424270  

    Human Recombinant Protein Products for SFXN1: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SFXN1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    SFXN1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SFXN: Sideroflexins

    1 InterPro protein domain:
     IPR004686 Mtc

    Graphical View of Domain Structure for InterPro Entry Q9H9B4

    ProtoNet protein and cluster: Q9H9B4

    1 Blocks protein domain: IPB004686 Tricarboxylate/iron carrier

    UniProtKB/Swiss-Prot: SFXN1_HUMAN, Q9H9B4
    Similarity: Belongs to the sideroflexin family


    SFXN1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SFXN1_HUMAN, Q9H9B4
    Function: Might be involved in the transport of a component required for iron utilization into or out of the
    mitochondria

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008324cation transmembrane transporter activity IEA--
         
    SFXN1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Sfxn1 (no phenotypes)

    SFXN1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SFXN1 
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    miRTarBase miRNAs that target SFXN1:
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    8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate SFXN1 (see all 30):
    hsa-miR-30c hsa-miR-142-5p hsa-miR-3673 hsa-miR-562 hsa-miR-15a hsa-miR-503 hsa-miR-16-1* hsa-miR-30d
    SwitchGear 3'UTR luciferase reporter plasmidSFXN1 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFXN1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SFXN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/267 Interacting proteins for SFXN1 (Q9H9B41, 2, 3 ENSP000003169054) via UniProtKB, MINT, STRING, and/or I2D (see all 267)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K92, 3, ENSP000003586224MINT-48148 I2D: score=2 STRING: ENSP00000358622
    TSC22D1Q157141, 3EBI-355861,EBI-712609 I2D: score=2 
    PGRMC1O002641, 3, ENSP000002179714EBI-355861,EBI-1045534 I2D: score=2 STRING: ENSP00000217971
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    UBA5Q9GZZ93, ENSP000003485654I2D: score=3 STRING: ENSP00000348565
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006812cation transport ----
    GO:0006826iron ion transport IEA--
    GO:0030218erythrocyte differentiation IEA--
    GO:0055072iron ion homeostasis IEA--
    GO:0055085transmembrane transport ----

    SFXN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SFXN1

    1 HMDB Compound for SFXN1    About this table
    CompoundSynonyms CAS #PubMed Ids
    IronArmco iron (see all 19)7439-89-6--

    Search CenterWatch for drugs/clinical trials and news about SFXN1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SFXN1 gene: 
    NM_022754.5  

    Unigene Cluster for SFXN1:

    Sideroflexin 1
    Hs.369440  [show with all ESTs]
    Unigene Representative Sequence: NM_022754
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507017 ENST00000321442(uc003mda.2) ENST00000508290 ENST00000507395
    ENST00000515791 ENST00000502393 ENST00000507823(uc003mdb.1) ENST00000513725
    ENST00000506963 ENST00000502865 ENST00000515736 ENST00000421887
    miRNA
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    8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate SFXN1 (see all 30):
    hsa-miR-30c hsa-miR-142-5p hsa-miR-3673 hsa-miR-562 hsa-miR-15a hsa-miR-503 hsa-miR-16-1* hsa-miR-30d
    SwitchGear 3'UTR luciferase reporter plasmidSFXN1 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SFXN1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SFXN1

    Additional mRNA sequence: 

    AK022287.1 AK022938.1 AK025032.1 AK056915.1 BC020517.1 BC063241.1 BX648188.1 

    14 DOTS entries:

    DT.413038  DT.40257647  DT.100047356  DT.91918185  DT.91749122  DT.100792319  DT.100808897  DT.102830359 
    DT.91643054  DT.120806935  DT.120806967  DT.65287012  DT.91992105  DT.97771092 

    24/211 AceView cDNA sequences (see all 211):

    BE550926 AI014241 BX509399 BM128746 BM928783 BQ216550 CN481191 BU956596 
    BX369174 AA973546 BC020517 F11510 AW614734 BP363027 AW502257 CN482188 
    BQ225449 BX951549 BG235896 BX483956 CA865759 BQ421555 CR599132 BE741335 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for SFXN1 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                                -           -                                   -                 -     -               
    SP2:              -                 -           -                                   -                                       
    SP3:                                -           -                       -           -                 -     -               
    SP4:                                -           -                                                                           
    SP5:                                -                                                                                       


    ECgene alternative splicing isoforms for SFXN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SFXN1 expression in normal human tissues (normalized intensities)      SFXN1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTGTAGAT
    SFXN1 Expression
    About this image


    SFXN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             cd3+ t cells   
     
     Liver (Hepatobiliary System)
             Periportal Hepatocytes Liver Lobule
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer

    See SFXN1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SFXN1

    SOURCE GeneReport for Unigene cluster: Hs.369440
        SABiosciences Expression via Pathway-Focused PCR Array including SFXN1: 
              Hematopoiesis in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFXN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SFXN1 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sfxn11 , 5 sideroflexin 11, 5 84.58(n)1
    94.72(a)1
      13 (28.40 cM)5
    140571  NM_027324.51  NP_081600.11 
     540718455 
    chicken
    (Gallus gallus)
    Aves SFXN11 sideroflexin 1 81.37(n)
    90.99(a)
      416221  XM_414544.3  XP_414544.2 
    lizard
    (Anolis carolinensis)
    Reptilia SFXN16
    Uncharacterized protein
    81(a)
    1 ↔ 1
    2(137172283-137205488)
    African clawed frog
    (Xenopus laevis)
    Amphibia xm278-prov2 sideroflexin 1 75(n)    BC044027.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sfxn11 sideroflexin 1 75.05(n)
    84.16(a)
      445143  NM_001003537.1  NP_001003537.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG117391 CG11739 55.38(n)
    55.38(a)
      40552  NM_164347.2  NP_730823.2 
    worm
    (Caenorhabditis elegans)
    Secernentea sfxn-1.51 Protein SFXN-1.5 58.01(n)
    55.13(a)
      181353  NM_077548.3  NP_509949.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes FSF16
    Putative protein, predicted to be an alpha-isoprop...
    37(a)
    1 → many
    XV(831059-832042)


    ENSEMBL Gene Tree for SFXN1 (if available)
    TreeFam Gene Tree for SFXN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SFXN1 gene
    SFXN42  SFXN52  SFXN22  SFXN32  
    3 SIMAP similar genes for SFXN1 using alignment to 5 protein entries:     SFXN1_HUMAN (see all proteins):
    SFXN3    SFXN2    SFXN5

    SFXN1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1344 SNPs in SFXN1 are shown (see all 1344)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1176756801,2
    C,F--174903547(+) GGAGCG/AGAGCC 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs1141754571,2
    F--174903644(+) TGACCA/TTAGAC 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs1439232631,2
    --174903728(+) ACTAAA/TTGTTT 1 -- us2k10--------
    rs2673491,2
    C,F,A,H--174903767(-) CTATAT/AGACAA 1 -- us2k129Minor allele frequency- A:0.48NS EA NA WA CSA 2669
    rs1135902981,2
    C,F--174903779(+) ATTACT/CGTGGC 1 -- us2k12Minor allele frequency- C:0.03CSA WA 120
    rs1807412231,2
    --174903976(+) TTGCTC/TACAAG 1 -- us2k10--------
    rs1162640371,2
    F--174904080(+) CACCTA/GGGTTG 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs1866526761,2
    --174904110(+) CAGCCA/GACTGC 1 -- us2k10--------
    rs1506313071,2
    --174904180(+) CATACA/GCCACC 1 -- us2k10--------
    rs584980061,2
    C--174904278(+) CACTCC/TGGCCT 1 -- us2k12Minor allele frequency- T:0.19WA 120

    HapMap Linkage Disequilibrium report for SFXN1 (174904065 - 174956745 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SFXN1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv469707CNV Loss16826518

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for SFXN1:    About MalaCards
    neonatal anemia    aceruloplasminemia    sideroblastic anemia    anemia

    1 disease from the University of Copenhagen DISEASES database for SFXN1:
    Aceruloplasminemia

    SFXN1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SFXN1
    Human Genome Epidemiology (HuGE) Navigator: SFXN1 (1 document)

    Export disorders for SFXN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SFXN1 gene, integrated from 9 sources (see all 38):
    (articles sorted by number of sources associating them with SFXN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. (PubMed id 23464991)1 Scifo E....Lalowski M. (2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. PKCe promotes oncogenic functions of ATF2 in the nucle us while blocking its apoptotic function at mitochondria. (PubMed id 22304920)1 Lau E....Ronai Z.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. (PubMed id 21081666)1 Greco T.M....Cristea I.M. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 94081 HGNC: 16085 AceView: SFXN1 Ensembl:ENSG00000164466 euGenes: HUgn94081
    ECgene: SFXN1 H-InvDB: SFXN1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SFXN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SFXN1 gene:
    Search GeneIP for patents involving SFXN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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