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SFTPD Gene

protein-coding GIFtS: 62

GC10M081687

surfactant protein D
(Previous names: surfactant, pulmonary-associated protein D )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: SFTP4)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
COLEC7 ^¹, ²
OTTHUMP00000019944 ^²
PSP-D ^², ³
PSPD ^³
SFTP4 ^², ³, ⁵
SP-D ^¹, ², ³

Descriptions
Lung surfactant protein D ^³
collectin 7 ^²
pulmonary surfactant apoprotein ^²
pulmonary surfactant-associated protein D ^²
surfactant protein D ^²
surfactant, pulmonary-associated protein D ^¹, ²
surfactant-associated protein, pulmonary 4 ^²

External Ids
HGNC: 10803¹
Entrez Gene: 6441²
UniProtKB: P35247³
Ensembl: ENSG00000133661⁷

Search outside databases for aliases for SFTPD gene

Previous GC identifers: GC10M080654 GC10M080919 GC10M081828 GC10M081362 GC10M081019

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SFTPD_HUMAN, P35247

Function: Contributes to the lung's defense against inhaled microorganisms. May participate in the

extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues

and to a lesser extent other alpha-glucosyl moieties

Gene Wiki entry for SFTPD (Surfactant_protein_D)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SFTPD gene

Entrez Gene cytogenetic band: 10q22.2-q23.1 Ensembl cytogenetic band: 10q22.3 HGNC cytogenetic band: 10q22.2-q23.1

SFTPD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M081687: (about GC identifiers)

Start:	81,687,476 bp from pter
End:	81,698,841 bp from pter
Size:	11,366 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000010.9 NT_030059.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SFTPD_HUMAN, P35247 (See protein sequence)

Recommended Name: Pulmonary surfactant-associated protein D precursor

Size: 375 amino acids; 37698 Da

Subunit: Oligomeric complex of 4 set of homotrimers

Subcellular location: Secreted, extracellular space, extracellular matrix. Secreted, extracellular

space, surface film

Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4

surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D)

and 2 small hydrophobic proteins (SP-B and SP-C)

PDB structures from and Proteopedia :

1B08 (3D)

1M7L (3D)

1PW9 (3D)

1PWB (3D)

2GGU (3D)

2GGX (3D)

2ORJ (3D)

2ORK (3D)

2OS9 (3D)

2RIA (3D)

2RIB (3D)

2RIC (3D)

2RID (3D)

2RIE (3D)

3DBZ (3D)

3G81 (3D)

3G83 (3D)

3G84 (3D)

Secondary accessions: Q5T0M3 Q6FH08 Q86YK9 Q8TCD8 Q9UCJ2 Q9UCJ3

Post-translational modifications:

The N-terminus is blocked¹

Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy

as this fits the requirement for 4-hydroxylation in vertebrates (By similarity)¹

REFSEQ proteins: NP_003010.4

ENSEMBL proteins:

ENSP00000378068 ENSP00000361366

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for SFTPD (SP-D)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Surfactant protein D)
	Human Recombinant Proteins from Abnova (SFTPD)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	9751757
GO:0005578	proteinaceous extracellular matrix	IEA	--
GO:0005764	lysosome	TAS	10485905
GO:0030139	endocytic vesicle	TAS	10485905

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Antibodies for SFTPD:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of SFTPD
	Sigma-Aldrich Antibodies for SFTPD
	R&D Systems Antibodies for SFTPD (SP-D)
	Antibodies from Abcam (Surfactant protein D), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SFTPD)
	Novus Biologicals Antibodies for SFTPD

Assays for SFTPD:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P35247

ProtoNet protein and cluster: P35247

2 Blocks protein families:

IPB008160 Collagen triple helix repeat

IPB008161 Collagen helix repeat

UniProtKB/Swiss-Prot: SFTPD_HUMAN, P35247

Similarity: Belongs to the SFTPD family

Similarity: Contains 1 C-type lectin domain

Similarity: Contains 1 collagen-like domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SFTPD)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SFTPD)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003019

Applied Biosystems Silencer® siRNAs for SFTPD

Sigma-Aldrich siRNA for SFTPD

Sigma-Aldrich shRNA Panels and shRNA for SFTPD

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SFTPD
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_003019
Myc/DDK tagged cDNA clone in CMV expression vector: NM_003019
untagged cDNA clone in CMV expression vector: NM_003019

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003019

UniProtKB/Swiss-Prot: SFTPD_HUMAN, P35247

Function: Contributes to the lung's defense against inhaled microorganisms. May participate in the

extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues

and to a lesser extent other alpha-glucosyl moieties

Genatlas biochemistry entry for SFTPD:

surfactant-associated glycoprotein D member of the collectin family,pulmonary,playing an important

role in innate immunity by binding to specific carbohydrate structures found at the surface of

pathogenic microorganisms

6 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Sftpd):

growth/size	hematopoietic system	homeostasis/metabolism	immune system	life span-post-weaning/aging
respiratory system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--
GO:0005529	sugar binding	TAS	10485905
GO:0008367	bacterial binding	TAS	9751757

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SFTPD

5/19 Interacting proteins for SFTPD (ENSP00000361366³) via UniProtKB, MINT, and/or STRING (see all 19 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DMBT1	ENSP00000357911³	STRING (score=.998)
SIRPA	ENSP00000348307³	STRING (score=.965)
SFTPC	ENSP00000316152³	STRING (score=.963)
SFTPB	ENSP00000345161³	STRING (score=.961)
DCN	ENSP00000052754³	STRING (score=.941)

About this table

5/12 Gene Ontology (GO) biological process terms (links to tree view) (see all 12 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001817	regulation of cytokine production	NAS	9751757
GO:0006800	oxygen and reactive oxygen species metabolic process	TAS	10485905
GO:0006898	receptor-mediated endocytosis	TAS	10485905
GO:0007585	respiratory gaseous exchange	IEA	--
GO:0042130	negative regulation of T cell proliferation	TAS	10485905

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SFTPD
10/25 Novoseek chemical compound relationships for SFTPD gene (see all 25 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
mannan	71.77	9	10224141 (1), 11045608 (1), 12816736 (1), 9153228 (1) (see all 8)
maltose	66.88	23	17915943 (3), 9153228 (2), 8918587 (1), 9700129 (1) (see all 16)
mannose	66.65	30	17915943 (2), 17567900 (2), 15187139 (2), 19249874 (2) (see all 18)
allergens	42.32	36	9367408 (5), 17202930 (4), 12706535 (4), 15905537 (3) (see all 11)
hydroxylysine	40.76	1	1339284 (1)
phospholipid	39.70	10	10666121 (3), 9870921 (1), 10456901 (1), 9813383 (1) (see all 6)
phosphatidylinositol	35.72	31	1400434 (6), 1457414 (5), 17417879 (3), 16834340 (2) (see all 9)
ethylenediaminetetraacetic acid	28.37	8	8424457 (2), 8918587 (1), 17177680 (1), 11306442 (1)
lipid	22.25	23	10666121 (3), 1457414 (2), 16387789 (2), 11667972 (1) (see all 11)
n-acetylglucosamine	19.47	2	15115749 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SFTPD)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SFTPD)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_003019

Sigma-Aldrich siRNA for SFTPD

Sigma-Aldrich shRNA Panels and shRNA for SFTPD

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003019

REFSEQ mRNAs for SFTPD gene:

NM_003019.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003019

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_003019
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_003019
                                 untagged cDNA clone in CMV expression vector: NM_003019

Additional cDNA sequence:

BC022318.1 CR541948.1

1 DOTS entry:

DT.91644675

24/43 AceView cDNA sequences (see all 43 ):

BX282004 BM972342 AI924488 AI732255 BM985387 BI819407 BF446634 BI820618

BI820265 NM_003019 BG482911 BI822450 BI770406 BM985241 BE465060 BC022318

CR541948 BI821373 BQ029770 X65018 BI489632 BM994163 BQ030140 AI820677

highest scoring ESTs for SFTPD:

BC022318 X65018 AA016042 AA487101 AA617783 AI002217 AI732255 AI807697 AI820677 AI924488

Unigene Cluster for SFTPD:

Surfactant protein D

Hs.253495 [show with all ESTs]

Unigene Representative Sequence: BC022318

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000394567 ENST00000372292

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SFTPD expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SFTPD

¹ / ² / ³

3 probe-sets matching SFTPD gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
31775_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	X65018	0.80	1.00	0.91	1
214199_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_003019	0.60	1.00	0.82	1
214199_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks SFTPD for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTGCCAATAT

SOURCE GeneReport for Unigene cluster: Hs.253495
Expression variation in blood from EXPOLDB for SFTPD

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SFTPD gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SFTPD¹	--	surfactant protein D	80.89(n) 76.53(a)	489066 XM_546184.2 XP_546184.2
cow (Bos taurus)	SFTPD¹	--	surfactant protein D	81.3(n) 74.25(a)	282072 NM_181026.2 NP_851369.1
rat (Rattus norvegicus)	Sftpd¹	--	surfactant protein D	78.61(n) 75.13(a)	25350 NM_012878.1 NP_037010.1
mouse (Mus musculus)	Sftpd^{1, 5}	14 (14.00 cM)⁵	surfactant associated protein D^{1, 5}	79.59(n)¹ 74.87(a)¹	20390¹ NM_009160.1¹ NP_033186.1¹ AF047741⁵ AF047742⁵ (see all 15)

About this table Species with no ortholog for SFTPD

ENSEMBL Gene Tree for SFTPD

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SFTPD gene

SFTPA1² SFTPA1B² SFTPA2B² MBL2² SFTPA2² ENSG00000220191²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/146 NCBI SNPs in SFTPD are shown (see all 146 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 143)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs721917^1,2	A,C,F,H,O	81696304(-)	`AACAAC/TGCCCA`	1	M/T	mis¹ ese³		24	EA NA MN CSAM NS EU WA	3274
	rs3088308^1,2	A,C,F,H	81687848(+)	`TGGAGA/TGGCCA`	1	S/T	mis¹		14	MN NA NS EU EA WA	1258
	rs10887215^1,2	A,C,F,H	81699756(+)	`TAATTT/CTTTAC`	1	--	ng3¹ tfbs³		6	EU EA WA NS	486
	rs2243639^1,2	A,C,F,H	81691702(+)	`CCCTGC/TGTTTC`	1	T/A	mis¹ ese³		18	EU EA WA MN CSAM NA NS	1478
	rs12770776^1,2	C,F,H	81699524(+)	`TGTGCA/GCTGTT`	1	--	ng3¹		6	EU EA WA NS	508
	rs4469829^1,2	C,F,H	81687791(+)	`AGCCTC/TGTTCT`	1	E/K	mis¹		12	NS EU EA WA	1146
--	rs6583888^1,2	A,C,F	81687177(+)	`tcaaaA/Caaaaa`	1	--	ng5¹		2	NS	92
	rs12219080^1,2	C,F,H	81699259(+)	`CACTGC/TCCAGA`	1	--	ng3¹		12	NS EU EA WA	1170
--	rs2819099^1,2	A,C,F	81687253(-)	`cctgcG/Agatct`	1	--	ng5¹		5	NA NS	234
--	rs1923536^1,2	A,C,F	81699789(-)	`ccagcG/Atgggc`	1	--	ng3¹		2	NS	92

About this table

HapMap Linkage Disequilibrium images for SFTPD (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 178635

10/69 Novoseek disease relationships for SFTPD gene (see all 69 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pulmonary alveolar proteinosis	80.46	21	8424457 (2), 19046553 (2), 8046250 (2), 11355171 (1) (see all 12)
lung diseases interstitial	75.09	24	11818324 (2), 12421999 (2), 19286849 (2), 14522914 (1) (see all 14)
bronchoalveolar lavage fluid	73.65	38	19046553 (2), 8918587 (1), 10497393 (1), 15274124 (1) (see all 26)
pneumonia interstitial	68.64	32	12692985 (3), 10846395 (2), 11475580 (2), 17874049 (2) (see all 15)
respiratory distress syndrome	67.93	10	14522914 (1), 16188791 (1), 19348329 (1), 16472150 (1) (see all 9)
lung diseases	67.83	57	10897675 (4), 16684127 (4), 16517507 (3), 16472150 (2) (see all 29)
fibrosis idiopathic pulmonary	65.57	12	11896896 (1), 11321887 (1), 16798048 (1), 17966103 (1) (see all 8)
pneumonitis hypersensitivity	64.55	5	11083713 (1), 9844346 (1), 16319337 (1), 17874049 (1)
acute eosinophilic pneumonia	63.40	2	15357266 (1), 16157978 (1)
acute respiratory distress	56.90	7	14522914 (1), 16472150 (1), 15244040 (1), 10452960 (1) (see all 6)

About this table

Human Gene Mutation Database: SFTPD
Genetic Association Database: SFTPD
Human Genome Epidemiology Navigator: SFTPD (20 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/411 PubMed articles for SFTPD gene (see all 411 ):

Purification, characterization and cDNA cloning of human lung surfactant protein D. (PubMed id 1339284)^{1, 2, 3, 4} Lu J....Reid K.B. (1992)
Human surfactant protein D: SP-D contains a C-type lectin carbohydrate recognition domain. (PubMed id 1898081)^{1, 2, 3, 4} Rust K.... Crouch E. (1991)
Polymorphisms in the human surfactant protein-D (SFTPD) gene: strong evidence that serum levels of surfactant protein-D (SP-D) are genetically influenced. (PubMed id 15700120)^{1, 3, 6} Heidinger K....Bein G. (2005)
A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D. (PubMed id 15661913)^{1, 3, 6} Leth-Larsen R....Holmskov U. (2005)
Accumulation of surfactant protein D in human pulmonary alveolar proteinosis. (PubMed id 8424457)^{1, 3, 4} Crouch E.... Chang D. (1993)
Genomic organization of human surfactant protein D (SP-D). SP-D is encoded on chromosome 10q22.2-23.1. (PubMed id 8428971)^{1, 3, 4} Crouch E.... Grosso L. (1993)
Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis. (PubMed id 13680361)^{1, 3, 6} Selman M.... Floros J. (2003)
Data mining and multiparameter analysis of lung surfactant protein genes in bronchopulmonary dysplasia. (PubMed id 15102713)^{3, 6} Rova M....Hallman M. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{3, 4} Deloukas P.... Rogers J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 6441	HGNC: 10803	AceView: SFTPD	Ensembl:ENSG00000133661	euGenes: HUgn6441
ECgene: SFTPD	H-InvDB: SFTPD

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
SeattleSNPs	http://pga.gs.washington.edu/data/sftpd/
Functional Glycomics Gateway - Glycan Binding	http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_228

Licensable Technologies for SFTPD
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SFTPD:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SFTPD-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SFTPD		Antibodies for SFTPD
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SFTPD		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SFTPD)
	Antibodies (SFTPD)
	Chimera RNAi (SFTPD)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Surfactant protein D)
	Antibodies (Surfactant protein D)

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Search Tocris compounds for SFTPD

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Antibodies for SFTPD

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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SFTPD Gene at Home site.
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SFTPD Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for SFTPD

Summaries
for SFTPD

Genomic Location
for SFTPD

Proteins
for SFTPD

Protein Domains/
Families
for SFTPD

Gene Function
for SFTPD

Pathways & Interactions
for SFTPD

Drugs & Compounds
for SFTPD

Transcripts
for SFTPD

Expression
for SFTPD

Orthologs
for SFTPD

Paralogs
for SFTPD

SNPs/Variants
for SFTPD

Disorders & Mutations
for SFTPD

Medical News
for SFTPD

Publications
for SFTPD

Search for SFTPD

Genome Databases showing SFTPD

Other Databases showing SFTPD

Specialized Databases showing SFTPD

Licensable Technologies
for SFTPD

Services
for SFTPD

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SFTPD Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor SFTPD

Summariesfor SFTPD

Genomic Locationfor SFTPD

Proteinsfor SFTPD

Protein Domains/Familiesfor SFTPD

Gene Functionfor SFTPD

Pathways & Interactionsfor SFTPD

Drugs & Compoundsfor SFTPD

Transcriptsfor SFTPD

Expression for SFTPD

Orthologsfor SFTPD

Paralogsfor SFTPD

SNPs/Variantsfor SFTPD

Disorders & Mutationsfor SFTPD

Medical Newsfor SFTPD

Publicationsfor SFTPD

Search for SFTPD

Genome Databases showing SFTPD

Other Databases showing SFTPD

Specialized Databases showing SFTPD

Licensable Technologiesfor SFTPD

Servicesfor SFTPD

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SFTPD

Summaries
for SFTPD

Genomic Location
for SFTPD

Proteins
for SFTPD

Protein Domains/
Families
for SFTPD

Gene Function
for SFTPD

Pathways & Interactions
for SFTPD

Drugs & Compounds
for SFTPD

Transcripts
for SFTPD

Expression
for SFTPD

Orthologs
for SFTPD

Paralogs
for SFTPD

SNPs/Variants
for SFTPD

Disorders & Mutations
for SFTPD

Medical News
for SFTPD

Publications
for SFTPD

Licensable Technologies
for SFTPD

Services
for SFTPD