Aliases for SFTPD Gene
External Ids for SFTPD Gene
Previous HGNC Symbols for SFTPD Gene
Previous GeneCards Identifiers for SFTPD Gene
GeneCards Summary for SFTPD Gene
SFTPD (Surfactant Protein D) is a Protein Coding gene. Diseases associated with SFTPD include wilson-mikity syndrome and aspergillosis. Among its related pathways are FOXA1 transcription factor network and Bacterial infections in CF airways. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is COLEC11.
UniProtKB/Swiss-Prot for SFTPD Gene
Contributes to the lungs defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.