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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SFTPA2 Gene

protein-coding GIFtS: 53
GCID: GC10M081305

surfactant protein A2

(Previous names: surfactant, pulmonary-associated protein A2 )

Explore 18 diseases affiliated with
SFTPA2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Surfactant Protein A2¹ ²		SP-A² ³
COLEC5¹ ² ³ ⁵		SPA2² ⁵
SP-A2¹ ³		Surfactant, Pulmonary-Associated Protein A2¹
Alveolar Proteinosis Protein² ³		SPAII²
35 KDa Pulmonary Surfactant-Associated Protein² ³		Collectin 5²
PSAP² ³		Pulmonary Surfactant-Associated Protein A2²
PSP-A² ³		Surfactant, Pulmonary-Associated Protein A2A²
PSPA² ³		Collectin-5³
SFTP1² ³		SFTPA³
SFTPA2B² ³

External Ids:	HGNC: 10799¹	Entrez Gene: 729238²	Ensembl: ENSG00000185303⁷	OMIM: 178642⁵	UniProtKB: Q8IWL1³

Export aliases for SFTPA2 gene to outside databases

Previous GC identifers: GC10M080272 GC10M080525 GC10M081528 GC10M080980 GC10M075310

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SFTPA2:

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10.

Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate

recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays

only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were

thought to have resulted from a duplication. (provided by RefSeq, Sep 2009)

UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1

Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface

tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SFTPA2 gene promoter:
MZF-1 GR NCX/Ncx GR-alpha Roaz
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SFTPA2 promoter sequence

Search SABiosciences Chromatin IP Primers for SFTPA2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SFTPA2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q22.3 Ensembl cytogenetic band: 10q22.3 HGNC cytogenetic band: 10q22.3

SFTPA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SFTPA2 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10M081305: view genomic region (about GC identifiers)

Start:	81,315,608 bp from pter	End:	81,320,163 bp from pter
Size:	4,556 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1 (See protein sequence)

Recommended Name: Pulmonary surfactant-associated protein A2 precursor

Size: 248 amino acids; 26182 Da

Subunit: Oligomeric complex of 6 set of homotrimers

Subcellular location: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film

Miscellaneous: Pulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins:

2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C)

Secondary accessions: A4QPA7 B2RXI6 B2RXK9 C9J9I7 E3VLC6 E3VLC7 E3VLC8 E3VLC9 P07714 Q14DV3 Q5RIR8

Q5RIR9

Explore the universe of human proteins at neXtProt for SFTPA2: NX_Q8IWL1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8IWL1

SFTPA2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001092138.1

ENSEMBL proteins:

ENSP00000361400 ENSP00000397375 ENSP00000361402

Reactome Protein details: Q8IWL1
Human Recombinant Protein Products:

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	Uscn Proteins for SFTPA2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	--
GO:0005581	collagen	IEA	--
GO:0005615	extracellular space	IEA	--

SFTPA2 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for SFTPA2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SFTPA2 for domains About GeneDecksing

5 InterPro domains/families:

IPR016187 C-type_lectin_fold

IPR018378 C-type_lectin_CS

IPR016186 C-type_lectin-like

IPR001304 C-type_lectin

IPR008160 Collagen

Graphical View of Domain Structure for InterPro Entry Q8IWL1

ProtoNet protein and cluster: Q8IWL1

1 Blocks protein family: IPB008160 Collagen triple helix repeat

UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1

Similarity: Belongs to the SFTPA family

Similarity: Contains 1 C-type lectin domain

Similarity: Contains 1 collagen-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1

Function: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface

tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SFTPA2
		1 QIAGEN miScript miRNA Assays for microRNA that regulate SFTPA2:
		hsa-miR-4291
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In Situ Assay
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Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0030246	carbohydrate binding	IEA	--

SFTPA2 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

FOXA1 transcription factor network

FOXA1 transcription factor network

1.00

Signal regulatory protein (SIRP) family interactions

Signal regulatory protein (SIRP) family interactions

1.00

Cell-cell junction organization

Cell-Cell communication

0.45

Pathway sources
See GeneCards unified pathways
Show all pathways

1 BioSystems Pathway for SFTPA2

FOXA1 transcription factor network

2 Reactome Pathways for SFTPA2

	Signal regulatory protein (SIRP) family interactions
	Cell-Cell communication

SFTPA2 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for SFTPA2

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

4 Interacting proteins for SFTPA2 (Q8IWL1³ ENSP00000361400⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LY96	Q9Y6Y9³	I2D: score=1
TLR4	O00206³	I2D: score=1
SFTPA1	ENSP00000361382⁴	STRING: ENSP00000361382
CD93	ENSP00000246006⁴	STRING: ENSP00000246006

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007585	respiratory gaseous exchange	IEA	--

SFTPA2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SFTPA2

1 HMDB Compound for SFTPA2 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about SFTPA2 / SFPA2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SFTPA2 gene:

NM_001098668.2

Unigene Cluster for SFTPA2:

Surfactant protein A2

Hs.523084 [show with all ESTs]

Unigene Representative Sequence: NM_001098668

7 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000372325(uc001kal.4 uc001kan.4) ENST00000417041(uc001kam.2)

ENST00000492049 ENST00000484410 ENST00000491208 ENST00000486566 ENST00000372327

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SFTPA2
		1 QIAGEN miScript miRNA Assays for microRNA that regulate SFTPA2:
		hsa-miR-4291
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Additional cDNA sequence:

AK225599.1 AK298041.1 AK298074.1 AK298114.1 AK313179.1 AK316192.1 BC111571.1 BC139727.1

BC157866.1 BC157890.1 HQ021421.1 HQ021422.2 HQ021423.2 HQ021424.1 HQ021425.2 HQ021426.1

HQ021427.1 HQ021428.2 HQ021429.2 HQ021430.1 HQ021431.2 HQ021432.1 K03475.1 S69680.1

S69683.1 S69687.1 S69688.1 S69791.1

15 DOTS entries:

DT.418328 DT.97784300 DT.97827098 DT.92330441 DT.91765535 DT.91765534 DT.121286766 DT.121286855

DT.95374231 DT.95374233 DT.97832746 DT.100780256 DT.91765555 DT.95374232 DT.97833272

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SFTPA2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCCCAGCCA

About this image

SFTPA2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Alveolar type II cells (Derivation of mature...)

Lung

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SFTPA2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SFTPA2

SOURCE GeneReport for Unigene cluster: Hs.523084

SABiosciences Custom PCR Arrays for SFTPA2

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for SFTPA2 gene from 3/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	Q2LK96_CHICK⁶ Q90XB2_CHICK⁶	surfactant, pulmonary-associated protein A1	40(a) 39(a)	many ↔ many many ↔ many	6(5542217-5544682) 6(5550705-5556235)
lizard (Anolis carolinensis)	Reptilia	--	--	52(a)	1 → many	GL343233.1(1635384-1641691)
zebrafish (Danio rerio)	Actinopterygii	hbl4⁶ hbl1⁶ (see all 5)	hexose-binding lectin 1 (see all 5)	28(a) 26(a) (see all 5)	many ↔ many many ↔ many (see all 5)	2(37618223-37621667) 2(37633260-37635376)

ENSEMBL Gene Tree for SFTPA2 (if available)
TreeFam Gene Tree for SFTPA2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SFTPA2 gene

SFTPA1² COLEC11² SFTPD² COLEC12² MBL2² COLEC10² SCARA3²

7 SIMAP similar genes for SFTPA2 using alignment to 2 protein entries: SFPA2_HUMAN (see all proteins):

SP-2A SP-A1 SP-A2 SFTPA1 MBL2 SFTPD

COLEC10

SFTPA2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1

Polymorphism: At least 6 alleles of SFTPA2 are known: 1A, 1A(0), 1A(1), 1A(2), 1A(3) and 1A(4). The sequence shown is

that of allele 1A(0)

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Pop	Total sample
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs17886818^1,2	C,F,	--	75310167(-)	`CCACTA/TCTCCC`	1	--	ds500¹		2	NS	90
rs17878306^1,2	C,F,	--	75310262(-)	`CACTGC/TCCCAT`	1	--	ds500¹		2	NS	90
rs17878534^1,2	C,	--	75310283(-)	`CATGTC/TGGCTT`	1	--	ds500¹		2	NS	90
rs17880606^1,2	C,	--	75310382(-)	`CTTCCG/ATCCTC`	1	--	ds500¹		2	NS	90
rs17881720^1,2	C,F,	--	75310450(-)	`ACACCA/GTTTGG`	1	--	ds500¹		8	NS	752
rs17882033^1,2	C,	--	75310473(-)	`TGCTGG/AAGGTT`	1	--	ds500¹		2	NS	92
rs17884933^1,2	C,F,	--	75310746(-)	`ACTGGA/CTCCAA`	1	--	ut3¹		2	NS	90
rs4794^1,2	F,	--	75310896(+)	`AAGATT/CTTGTC`	1	--	ut3¹		3	MN	556
rs17884357^1,2	C,F,	--	75311072(-)	`CTCTTG/AGGGAT`	1	--	ut3¹		2	NS	94
rs17884561^1,2	C,F,	--	75311198(-)	`TCACAC/ACACCC`	1	--	ut3¹		2	NS	94

HapMap Linkage Disequilibrium report for SFTPA2 (81315608 - 81320163 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SFTPA2
1 CNV: 30512
Human Gene Mutation Database (HGMD): SFTPA2

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SFTPA2

DNA2.0 Custom Variant and Variant Library Synthesis for SFTPA2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SFTPA2 for disorders           About GeneDecksing

OMIM gene information: 178642
OMIM disorders: 178500
UniProtKB/Swiss-Prot: SFPA2_HUMAN, Q8IWL1

Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF) [MIM:178500]. Pulmonary fibrosis is a

lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying

degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage

lung disease

18 diseases for SFTPA2: About MalaCards

idiopathic pulmonary fibrosis pulmonary fibrosis fibrosis allergic bronchopulmonary aspergillosis

otitis media bronchopulmonary dysplasia allergic rhinitis aspergillosis

pulmonary edema rhinitis pulmonary tuberculosis eosinophilia

twinning alzheimer's disease tuberculosis lung cancer

urinary tract infection pulmonary fibrosis, familial

2 diseases from the University of Copenhagen DISEASES database for SFTPA2:

Aspergillosis Lung disease

Genetic Association Database (GAD): SFTPA2
Human Genome Epidemiology (HuGE) Navigator: SFTPA2 (22 documents)

Export disorders for SFTPA2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SFTPA2 gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with SFTPA2)

Utopia: connect your pdf to the dynamic
world of online information

Human SP-A1 (SFTPA1) variant-specific 3' UTRs and pol y(A) tail differentially affect the in vitro translation of a reporter gene. (PubMed id 20693318)^{1, 2} Silveyra P....Floros J. (2010)
Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer. (PubMed id 19100526)^{1, 2} Wang Y....Garcia C.K. (2009)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{1, 2} Deloukas P.... Rogers J. (2004)
Characterization of a second human pulmonary surfactant-associated protein SP-A gene. (PubMed id 1372511)^{1, 2} Katyal S.L.... Locker J.L. (1992)
Studies of the structure of lung surfactant protein SP-A. (PubMed id 2610270)^{1, 2} Haagsman H.P.... Clements J.A. (1989)
Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein. (PubMed id 3755136)^{1, 2} Floros J.... Fritsch E.F. (1986)
SP-A1, SP-A2 and SP-D gene polymorphisms in severe ac ute respiratory syncytial infection in Chilean infants. (PubMed id 21601013)¹ Ampuero S....LarraA+aga C.E. (2011)
The untranslated exon B of human surfactant protein A 2 mRNAs is an enhancer for transcription and translation. (PubMed id 21840962)¹ Silveyra P....Floros J. (2011)
Relationship between surfactant protein A polymorphis ms and allergic rhinitis in a Chinese Han population. (PubMed id 20963503)¹ Deng Y....He Q. (2010)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 729238	HGNC: 10799	Ensembl:ENSG00000185303	euGenes: HUgn729238	ECgene: SFTPA2
H-InvDB: SFTPA2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for SFTPA2	Pharmacogenomics, SNPs, Pathways
SeattleSNPs	http://pga.gs.washington.edu/data/sftpa2/

Intellectual Property for SFTPA2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for SFTPA2 gene:
Search GeneIP for patents involving SFTPA2

GeneCards and IP:
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SFTPA2 Gene

surfactant protein A2

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SFTPA2 (Gene Symbol)
Surfactant Protein A2
COLEC5
SP-A2
Alveolar Proteinosis Protein
35 KDa Pulmonary Surfactant-Associated Protein
PSAP
PSP-A
PSPA
SFTP1
SFTPA2B
SP-A
SPA2
Surfactant, Pulmonary-Associated Protein A2
SPAII
Collectin 5
Pulmonary Surfactant-Associated Protein A2
Surfactant, Pulmonary-Associated Protein A2A
Collectin-5
SFTPA

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SFTPA2 Gene

surfactant protein A2

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