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Aliases for SFT2D3 Gene

Aliases for SFT2D3 Gene

  • SFT2 Domain Containing 3 2 3
  • SFT2 Domain-Containing Protein 3 4

External Ids for SFT2D3 Gene

Previous GeneCards Identifiers for SFT2D3 Gene

  • GC02P128175
  • GC02P128458
  • GC02P120764

Summaries for SFT2D3 Gene

GeneCards Summary for SFT2D3 Gene

SFT2D3 (SFT2 Domain Containing 3) is a Protein Coding gene.

UniProtKB/Swiss-Prot for SFT2D3 Gene

  • May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SFT2D3 Gene

Genomics for SFT2D3 Gene

Regulatory Elements for SFT2D3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for SFT2D3 Gene

127,701,023 bp from pter
127,705,242 bp from pter
4,220 bases
Plus strand

Genomic View for SFT2D3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SFT2D3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SFT2D3 Gene

Proteins for SFT2D3 Gene

  • Protein details for SFT2D3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Vesicle transport protein SFT2C
    Protein Accession:
    Secondary Accessions:
    • Q8N2P9

    Protein attributes for SFT2D3 Gene

    215 amino acids
    Molecular mass:
    21790 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SFT2D3 Gene

Proteomics data for SFT2D3 Gene at MOPED

Post-translational modifications for SFT2D3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SFT2D3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for SFT2D3

No data available for DME Specific Peptides for SFT2D3 Gene

Domains for SFT2D3 Gene

Protein Domains for SFT2D3 Gene

Suggested Antigen Peptide Sequences for SFT2D3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q587I9
  • Belongs to the SFT2 family.
genes like me logo Genes that share domains with SFT2D3: view

No data available for Gene Families for SFT2D3 Gene

Function for SFT2D3 Gene

Molecular function for SFT2D3 Gene

UniProtKB/Swiss-Prot Function:
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SFT2D3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SFT2D3 Gene

Localization for SFT2D3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SFT2D3 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for SFT2D3 Gene COMPARTMENTS Subcellular localization image for SFT2D3 gene
Compartment Confidence
plasma membrane 3
peroxisome 1

Gene Ontology (GO) - Cellular Components for SFT2D3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SFT2D3: view

Pathways for SFT2D3 Gene

SuperPathways for SFT2D3 Gene

No Data Available

Interacting Proteins for SFT2D3 Gene

Gene Ontology (GO) - Biological Process for SFT2D3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with SFT2D3: view

No data available for Pathways by source for SFT2D3 Gene

Transcripts for SFT2D3 Gene

mRNA/cDNA for SFT2D3 Gene

(298) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SFT2D3 Gene

SFT2 domain containing 3:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SFT2D3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SFT2D3 Gene

No ASD Table

Relevant External Links for SFT2D3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for SFT2D3 Gene

mRNA expression in normal human tissues for SFT2D3 Gene

Protein differential expression in normal tissues for SFT2D3 Gene

This gene is overexpressed in Bone (32.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for SFT2D3 Gene

SOURCE GeneReport for Unigene cluster for SFT2D3 Gene Hs.345849

genes like me logo Genes that share expressions with SFT2D3: view

Expression partners for SFT2D3 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for SFT2D3 Gene

Orthologs for SFT2D3 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SFT2D3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia SFT2D3 35
  • 81.22 (n)
  • 81.22 (a)
SFT2D3 36
  • 78 (a)
(Mus musculus)
Mammalia Sft2d3 35
  • 79.4 (n)
  • 78.77 (a)
Sft2d3 16
Sft2d3 36
  • 79 (a)
(Pan troglodytes)
Mammalia SFT2D3 35
  • 98.91 (n)
  • 98.6 (a)
SFT2D3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Sft2d3 35
  • 78.6 (n)
  • 80.47 (a)
(Monodelphis domestica)
Mammalia SFT2D3 36
  • 63 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8266 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.29830 35
(Danio rerio)
Actinopterygii sft2d3 35
  • 56.96 (n)
  • 52.53 (a)
sft2d3 36
  • 42 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009524 35
  • 47.94 (n)
  • 34.57 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33635 35
  • 46.39 (n)
  • 44.06 (a)
CG33635 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea C18E9.10 35
  • 43.2 (n)
  • 41.84 (a)
C18E9.10 36
  • 25 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SFT2 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 31 (a)
Species with no ortholog for SFT2D3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SFT2D3 Gene

Gene Tree for SFT2D3 (if available)
Gene Tree for SFT2D3 (if available)

Paralogs for SFT2D3 Gene

No data available for Paralogs for SFT2D3 Gene

Variants for SFT2D3 Gene

Sequence variations from dbSNP and Humsavar for SFT2D3 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1048211 -- 127,701,465(+) ACCGA(A/G)CCGCT utr-variant-5-prime
rs6713423 -- 127,701,384(+) CGCAG(A/G)GCAGG utr-variant-5-prime
rs7580688 -- 127,700,367(+) AGAAT(A/G)TATTT upstream-variant-2KB
rs10174458 -- 127,701,673(+) CGGGC(C/T)TGCGC synonymous-codon, reference
rs10197061 -- 127,700,667(+) GGCAC(G/T)TGGGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SFT2D3 Gene

Variant ID Type Subtype PubMed ID
nsv875015 CNV Loss 21882294
dgv4299n71 CNV Loss 21882294
nsv470482 CNV Loss 18288195
dgv4301n71 CNV Loss 21882294
nsv875030 CNV Loss 21882294
nsv875033 CNV Loss 21882294

Relevant External Links for SFT2D3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SFT2D3 Gene

Disorders for SFT2D3 Gene

No disorders were found for SFT2D3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for SFT2D3 Gene

Publications for SFT2D3 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for SFT2D3 Gene

Sources for SFT2D3 Gene

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