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Aliases for SFT2D1 Gene

Aliases for SFT2D1 Gene

  • SFT2 Domain Containing 1 2 3
  • SFT2 Domain-Containing Protein 1 3 4
  • C6orf83 3 4
  • PRGR1 3 4
  • Chromosome 6 Open Reading Frame 83 2
  • Vesicle Transport Protein SFT2A 3

External Ids for SFT2D1 Gene

Previous Symbols for SFT2D1 Gene

  • C6orf83

Summaries for SFT2D1 Gene

GeneCards Summary for SFT2D1 Gene

SFT2D1 (SFT2 Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is SFT2D2.

UniProtKB/Swiss-Prot for SFT2D1 Gene

  • May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SFT2D1 Gene

Genomics for SFT2D1 Gene

Genomic Location for SFT2D1 Gene

Start:
166,319,728 bp from pter
End:
166,342,591 bp from pter
Size:
22,864 bases
Orientation:
Minus strand

Genomic View for SFT2D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SFT2D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SFT2D1 Gene

Regulatory Elements for SFT2D1 Gene

Proteins for SFT2D1 Gene

  • Protein details for SFT2D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WV19-SFT2A_HUMAN
    Recommended name:
    Vesicle transport protein SFT2A
    Protein Accession:
    Q8WV19
    Secondary Accessions:
    • Q5TI64
    • Q9UIC7

    Protein attributes for SFT2D1 Gene

    Size:
    159 amino acids
    Molecular mass:
    17804 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF18564.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for SFT2D1 Gene

Proteomics data for SFT2D1 Gene at MOPED

Post-translational modifications for SFT2D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for SFT2D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SFT2D1 Gene

Domains for SFT2D1 Gene

Protein Domains for SFT2D1 Gene

UniProtKB/Swiss-Prot:

SFT2A_HUMAN
Family:
  • Belongs to the SFT2 family.:
    • Q8WV19
genes like me logo Genes that share domains with SFT2D1: view

No data available for Gene Families for SFT2D1 Gene

Function for SFT2D1 Gene

Molecular function for SFT2D1 Gene

UniProtKB/Swiss-Prot Function: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.

Phenotypes for SFT2D1 Gene

GenomeRNAi human phenotypes for SFT2D1:
genes like me logo Genes that share phenotypes with SFT2D1: view

miRNA for SFT2D1 Gene

miRTarBase miRNAs that target SFT2D1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for SFT2D1 Gene

Localization for SFT2D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SFT2D1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SFT2D1 Gene COMPARTMENTS Subcellular localization image for SFT2D1 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for SFT2D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SFT2D1: view

Pathways for SFT2D1 Gene

SuperPathways for SFT2D1 Gene

No Data Available

Interacting Proteins for SFT2D1 Gene

Gene Ontology (GO) - Biological Process for SFT2D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
GO:0016192 vesicle-mediated transport IEA --
genes like me logo Genes that share ontologies with SFT2D1: view

No data available for Pathways by source for SFT2D1 Gene

Transcripts for SFT2D1 Gene

Unigene Clusters for SFT2D1 Gene

SFT2 domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SFT2D1 Gene

No ASD Table

Relevant External Links for SFT2D1 Gene

GeneLoc Exon Structure for
SFT2D1
ECgene alternative splicing isoforms for
SFT2D1

Expression for SFT2D1 Gene

mRNA expression in normal human tissues for SFT2D1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for SFT2D1 Gene

SOURCE GeneReport for Unigene cluster for SFT2D1 Gene Hs.487143

genes like me logo Genes that share expressions with SFT2D1: view

Orthologs for SFT2D1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for SFT2D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SFT2D1 36
  • 98.95 (n)
  • 98.74 (a)
SFT2D1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 79 (a)
OneToMany
SFT2D1 36
  • 87.84 (n)
  • 93.71 (a)
SFT2D1 37
  • 94 (a)
OneToMany
dog
(Canis familiaris)
Mammalia SFT2D1 36
  • 90.99 (n)
  • 94.34 (a)
SFT2D1 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm12166 37
  • 91 (a)
OneToMany
Sft2d1 36
  • 86.29 (n)
  • 91.77 (a)
Sft2d1 16
Sft2d1 37
  • 91 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia SFT2D1 37
  • 84 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SFT2D1 37
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Sft2d1 36
  • 86.37 (n)
  • 91.82 (a)
chicken
(Gallus gallus)
Aves SFT2D1 36
  • 76.1 (n)
  • 81.13 (a)
SFT2D1 37
  • 81 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SFT2D1 37
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia sft2d1 36
  • 73.38 (n)
  • 76.73 (a)
Str.11136 36
zebrafish
(Danio rerio)
Actinopterygii sft2d1 36
  • 67.71 (n)
  • 75.47 (a)
sft2d1 37
  • 74 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG5104 36
  • 59.33 (n)
  • 57.86 (a)
CG5104 37
  • 56 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea F27D4.7 37
  • 31 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G24170 36
  • 47.96 (n)
  • 39.35 (a)
rice
(Oryza sativa)
Liliopsida Os01g0219100 36
  • 49.89 (n)
  • 40.65 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 46 (a)
OneToMany
Species with no ortholog for SFT2D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for SFT2D1 Gene

ENSEMBL:
Gene Tree for SFT2D1 (if available)
TreeFam:
Gene Tree for SFT2D1 (if available)

Paralogs for SFT2D1 Gene

Paralogs for SFT2D1 Gene

Selected SIMAP similar genes for SFT2D1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with SFT2D1: view

Variants for SFT2D1 Gene

Sequence variations from dbSNP and Humsavar for SFT2D1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs7088 -- 166,322,874(-) CTGTC(A/C/G)TACAT synonymous-codon, reference, nc-transcript-variant
rs941683 -- 166,326,782(+) GTTCA(A/G)ACGTT intron-variant
rs979562 -- 166,325,686(+) ACACC(A/G)GGCAC intron-variant
rs979563 -- 166,325,744(+) ATGTG(C/T)GTTTA intron-variant
rs1046214 -- 166,320,348(+) TAACA(G/T)AACTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SFT2D1 Gene

Variant ID Type Subtype PubMed ID
nsv886934 CNV Loss 21882294

Relevant External Links for SFT2D1 Gene

HapMap Linkage Disequilibrium report
SFT2D1

Disorders for SFT2D1 Gene

Relevant External Links for SFT2D1

Genetic Association Database (GAD)
SFT2D1
Human Genome Epidemiology (HuGE) Navigator
SFT2D1
genes like me logo Genes that share disorders with SFT2D1: view

No data available for UniProtKB/Swiss-Prot for SFT2D1 Gene

Publications for SFT2D1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3

Products for SFT2D1 Gene

Sources for SFT2D1 Gene

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