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SFSWAP Gene

protein-coding   GIFtS: 50
GCID: GC12P132196

Splicing Factor, Suppressor Of White-Apricot Homolog (Drosophila)

(Previous names: splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot,...)
(Previous symbol: SFRS8)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Splicing Factor, Suppressor Of White-Apricot Homolog (Drosophila)1 2     Suppressor Of White Apricot Protein Homolog2 3
SFRS81 2 3     SWAP2 3
Splicing Factor, Arginine/Serine-Rich 8 (Suppressor-Of-White-Apricot
Homolog, Drosophila)1 2
     Splicing Factor, Suppressor Of White-Apricot Homolog2
Splicing Factor, Arginine/Serine-Rich 8 (Suppressor-Of-White-Apricot,
Drosophila Homolog)1 2
     Splicing Factor, Arginine/Serine-Rich 83

External Ids:    HGNC: 107901   Entrez Gene: 64332   Ensembl: ENSG000000619367   OMIM: 6019455   UniProtKB: Q128723   

Export aliases for SFSWAP gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SFSWAP Gene:
This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its
expression by control of splicing of its first two introns. In addition, it also regulates the splicing of
fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. (provided
by RefSeq, May 2012)

GeneCards Summary for SFSWAP Gene:
SFSWAP (splicing factor, suppressor of white-apricot homolog (Drosophila)) is a protein-coding gene. Diseases associated with SFSWAP include asthma, and tonsillitis. GO annotations related to this gene include RNA binding.

UniProtKB/Swiss-Prot: SFSWA_HUMAN, Q12872
Function: Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA
processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction
with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SFSWAP
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSFSWAP promoter sequence
   Search Chromatin IP Primers for SFSWAP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SFSWAP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.33   Ensembl cytogenetic band:  12q24.33   HGNC cytogenetic band: 12q24.33

SFSWAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SFSWAP gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P132196:  view genomic region     (about GC identifiers)

Start:
132,195,626 bp from pter      End:
132,284,282 bp from pter
Size:
88,657 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SFSWA_HUMAN, Q12872 (See protein sequence)
Recommended Name: Splicing factor, suppressor of white-apricot homolog  
Size: 951 amino acids; 104822 Da
2 PDB 3D structures from and Proteopedia for SFSWAP:
2E5Z (3D)        2E60 (3D)    
Secondary accessions: B2RN45 B7ZM97 F5H6B8 Q6PJF7
Alternative splicing: 2 isoforms:  Q12872-1   Q12872-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SFSWAP: NX_Q12872

Explore proteomics data for SFSWAP at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys473
  • Modification sites at PhosphoSitePlus

  • See SFSWAP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001248340.1  NP_004583.2  

    ENSEMBL proteins: 
     ENSP00000261674   ENSP00000445832   ENSP00000443045   ENSP00000437738   ENSP00000439957  

    SFSWAP Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
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    Browse Proteins at Cloud-Clone Corp.

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR019147 SWAP_N_domain
     IPR000061 Surp

    Graphical View of Domain Structure for InterPro Entry Q12872

    ProtoNet protein and cluster: Q12872

    1 Blocks protein domain: IPB000061 SWAP/Surp

    UniProtKB/Swiss-Prot: SFSWA_HUMAN, Q12872
    Similarity: Contains 2 SURP motif repeats


    SFSWAP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SFSWA_HUMAN, Q12872
    Function: Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA
    processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction
    with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
         
    SFSWAP for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SFSWAP:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SFSWAP
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SFSWAP
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SFSWAP

    miRNA
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    miRTarBase miRNAs that target SFSWAP:
    hsa-let-7a-5p (MIRT052638), hsa-mir-183-5p (MIRT047090)

    Block miRNA regulation of human, mouse, rat SFSWAP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SFSWAP (see all 10):
    hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-27a hsa-miR-374c hsa-miR-655 hsa-miR-138 hsa-miR-494 hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidSFSWAP 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SFSWAP

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFSWAP

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFSWAP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SFSWA_HUMAN, Q12872: Nucleus (Potential)

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    SFSWAP for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SFSWAP About                                                                                                See pathways by source

    SuperPathContained pathways About
    1mRNA Splicing - Major Pathway
    mRNA processing0.44


    1 BioSystems Pathway for SFSWAP
        mRNA processing


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SFSWAP
    Interactions:

        Search GeneGlobe Interaction Network for SFSWAP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for SFSWAP (Q128723 ENSP000002616744) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RNPS1Q152873, ENSP000003158594I2D: score=2 STRING: ENSP00000315859
    C16orf80Q9Y6A43I2D: score=5 
    SRRM1ENSP000003262614STRING: ENSP00000326261
    GPKOWENSP000001561094STRING: ENSP00000156109
    JMJD6ENSP000003940854STRING: ENSP00000394085
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006376mRNA splice site selection TAS8940107
    GO:0006396RNA processing ----
    GO:0006397mRNA processing TAS8940107

    SFSWAP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SFSWAP (SFSWA)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SFSWAP gene (3 alternative transcripts): 
    NM_001261411.1  NM_004592.3  NM_152235.1  

    Unigene Cluster for SFSWAP:

    Splicing factor, suppressor of white-apricot homolog (Drosophila)
    Hs.308171  [show with all ESTs]
    Unigene Representative Sequence: CR627024
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000540469 ENST00000261674(uc001uja.1 uc010tbn.1) ENST00000538548(uc001uiz.1)
    ENST00000535399 ENST00000535236(uc001ujb.1) ENST00000541286 ENST00000542813
    ENST00000535202 ENST00000537164 ENST00000539506 ENST00000537582
    miRNA
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    Block miRNA regulation of human, mouse, rat SFSWAP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate SFSWAP (see all 10):
    hsa-miR-520d-5p hsa-miR-513a-5p hsa-miR-27a hsa-miR-374c hsa-miR-655 hsa-miR-138 hsa-miR-494 hsa-miR-524-5p
    SwitchGear 3'UTR luciferase reporter plasmidSFSWAP 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SFSWAP
    Predesigned siRNA for gene silencing in human, mouse, rat SFSWAP
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SFSWAP (NM_004592)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFSWAP
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SFSWAP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SFSWAP
      QuantiTect SYBR Green Assays in human, mouse, rat SFSWAP
      QuantiFast Probe-based Assays in human, mouse, rat SFSWAP

    Additional mRNA sequence: 

    AB208921.1 AK295149.1 AK310836.1 BC008707.2 BC015953.2 BC024041.1 BC113420.1 BC136678.1 
    BC142980.1 BC144364.1 CR627024.1 U08377.1 

    12 DOTS entries:

    DT.452413  DT.97838402  DT.40117457  DT.100813702  DT.92464133  DT.95131294  DT.95131308  DT.100813700 
    DT.40233427  DT.86840920  DT.92435439  DT.95131302 

    Selected AceView cDNA sequences (see all 245):

    AI695018 AA256490 BM503889 CA393336 AA411069 BQ881166 BG681813 AW411150 
    AI363055 BQ268246 NM_152235 BM508912 CA439485 BQ001297 BM666535 BM676446 
    BU184997 CA447970 BU553501 AI356254 BM055253 NM_004592 BQ018725 BP432365 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SFSWAP (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                      -                                         -                                                                           
    SP2:                                                                                                                                                            
    SP3:                    -                 -                                                                                                                     
    SP4:                                      -                                                                                                                     
    SP5:                                                                                                                    -                                       

    ExUns: 19 ^ 20
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SFSWAP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SFSWAP expression in normal human tissues (normalized intensities)      SFSWAP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SFSWAP Expression
    About this image


    SFSWAP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    SFSWAP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SFSWAP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.308171
        Custom PCR Arrays for SFSWAP
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFSWAP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SFSWAP gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sfswap1 , 5 splicing factor, suppressor of white-apricot homolog more1, 5 83.67(n)1
    88.68(a)1
      5 (68.13 cM)5
    2317691  NM_172276.31  NP_758480.21 
     1295012315 
    chicken
    (Gallus gallus)
    Aves SFSWAP6
    splicing factor, suppressor of white-apricot homol...
    79(a)
    1 ↔ 1
    15(2778011-2817524)
    lizard
    (Anolis carolinensis)
    Reptilia SFSWAP6
    splicing factor, suppressor of white-apricot homol...
    75(a)
    1 ↔ 1
    GL343364.1(9969-44957)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3985372 similar to splicing factor, arginine/serine-rich 8 more 77(n)    BC042301.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc561842 similar to splicing factor, arginine/serine-rich 8 more 77.01(n)   394143  BC047839.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta su(w[a])6
    suppressor of white-apricot
    28(a)
    1 ↔ 1
    X(906812-940075)
    worm
    (Caenorhabditis elegans)
    Secernentea swp-16
    Protein SWP-1, isoform d
    26(a)
    1 ↔ 1
    III(5702255-5705466) WBGene00006359


    ENSEMBL Gene Tree for SFSWAP (if available)
    TreeFam Gene Tree for SFSWAP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SFSWAP gene
    1 SIMAP similar gene for SFSWAP using alignment to 4 protein entries:     SFSWA_HUMAN (see all proteins):
    SFRS8

    SFSWAP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SFSWAP (see all 1898)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs635933611,2
    C--132059438(+) TTTTT-/T/TT  
            
    GAGAC
    2 -- int11NA 2
    rs351892171,2
    C,F--132193730(+) CGTTAT/CGCAGT 2 -- us2k14Minor allele frequency- C:0.25NA 126
    rs1838850851,2
    --132193944(+) TTATTC/TGAGCA 2 -- us2k10--------
    rs1169109961,2
    C,F--132194088(+) CTTGCA/GTAGGA 2 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1497534201,2
    --132194131(+) GCCTCC/TTTATT 2 -- us2k10--------
    rs1149444001,2
    F--132194191(+) AGCACC/TGAAAC 2 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1867615401,2
    --132194217(+) TGGGGA/GCAAAC 2 -- us2k10--------
    rs1444348131,2
    --132194226(+) ACAACA/GGTGTT 2 -- us2k10--------
    rs1484139241,2
    --132194253(+) GACACA/GTACAT 2 -- us2k10--------
    rs1154952161,2
    F--132194320(+) GCCACG/ACATGC 2 -- us2k11Minor allele frequency- A:0.05WA 118

    HapMap Linkage Disequilibrium report for SFSWAP (132195626 - 132284282 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for SFSWAP (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746895CNV Deletion23290073
    esv2746894CNV Deletion23290073
    esv997559CNV Insertion20482838
    esv1251086CNV Insertion17803354
    nsv52992CNV Insertion16902084
    nsv899701CNV Loss21882294
    nsv899685CNV Loss21882294
    nsv832555CNV Loss17160897
    nsv9044CNV Gain18304495
    esv34554CNV Gain17911159

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 601945    OMIM disorders: --

    7 diseases for SFSWAP:    About MalaCards
    asthma    tonsillitis    thyroiditis    cerebritis
    malaria    endotheliitis    prostatitis


    SFSWAP for disorders           About GeneDecksing

    Genetic Association Database (GAD): SFSWAP

    Export disorders for SFSWAP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SFSWAP gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with SFSWAP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The mammalian homolog of suppressor-of-white-apricot regulates alternative mRNA splicing of CD45 exon 4 and fibronectin IIICS. (PubMed id 8940107)1, 2, 3 Sarkissian M.... Lafyatis R. (J. Biol. Chem. 1996)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. Conservation of regulated alternative splicing and identification of functional domains in vertebrate homologs to the Drosophila splicing regulator, suppressor-of-white-apricot. (PubMed id 8206918)1, 2 Denhez F. and Lafyatis R. (J. Biol. Chem. 1994)
    4. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    8. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    9. Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)2 Choudhary C.... Mann M. (Science 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6433 HGNC: 10790 AceView: SFRS8 Ensembl:ENSG00000061936 euGenes: HUgn6433
    ECgene: SFSWAP H-InvDB: SFSWAP

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for SFSWAP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SFSWAP gene:
    Search GeneIP for patents involving SFSWAP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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