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SFR1 Gene

protein-coding   GIFtS: 45
GCID: GC10P105882

SWI5-Dependent Recombination Repair 1

(Previous names: chromosome 10 open reading frame 78, MEI5 recombination...)
(Previous symbols: C10orf78, MEIR5)
  Search for SFR1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SWI5-Dependent Recombination Repair 11 2     bA373N18.12
C10orf781 2 3     MEI5 Recombination Repair Protein Homolog2
MEIR51 2 3     Swi5-Dependent Recombination DNA Repair Protein 1 Homolog2
Meiosis Protein 5 Homolog2 3     SWI5-Dependent Recombination Repair Protein 12
MEI52 3     CIZ15
Chromosome 10 Open Reading Frame 781     LNP945
MEI5 Recombination Repair Protein Homolog (S. Cerevisiae)1     ZNF3565

External Ids:    HGNC: 295741   Entrez Gene: 1193922   Ensembl: ENSG000001563847   OMIM: 6114205   UniProtKB: Q86XK33   

Export aliases for SFR1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SFR1 Gene:
SFR1 (SWI5-dependent recombination repair 1) is a protein-coding gene.

UniProtKB/Swiss-Prot: SFR1_HUMAN, Q86XK3
Function: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous
recombination




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for SFR1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): SFR1 promoter sequence
   Search Chromatin IP Primers for SFR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SFR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.1   Ensembl cytogenetic band:  10q25.1   HGNC cytogenetic band: 10q25.1

SFR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SFR1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P105882:  view genomic region     (about GC identifiers)

Start:
105,881,816 bp from pter      End:
105,886,143 bp from pter
Size:
4,328 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SFR1_HUMAN, Q86XK3 (See protein sequence)
Recommended Name: Swi5-dependent recombination DNA repair protein 1 homolog  
Size: 245 amino acids; 28262 Da
Subunit: Component of the SWI5-SFR1 complex. Interacts with RAD51; the interaction is weak
Secondary accessions: A8K569 B2RTV8 Q5JT39 Q5JT40 Q8WW47
Alternative splicing: 3 isoforms:  Q86XK3-1   Q86XK3-2   Q86XK3-3   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for SFR1: NX_Q86XK3

Explore proteomics data for SFR1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SFR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001002759.1  NP_660290.3  

    ENSEMBL proteins: 
     ENSP00000358744   ENSP00000358742   ENSP00000338089  

    SFR1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for SFR1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for SFR1
    GenScript Custom Purified and Recombinant Proteins Services for SFR1
    Novus Biologicals SFR1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for SFR1 

    SFR1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search for Antibodies for SFR1 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for SFR1
    LSBio Antibodies in human, mouse, rat for SFR1

    SFR1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for SFR1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR018468 Ds-recomb_repair_prot_Mei5

    Graphical View of Domain Structure for InterPro Entry Q86XK3

    ProtoNet protein and cluster: Q86XK3

    UniProtKB/Swiss-Prot: SFR1_HUMAN, Q86XK3
    Similarity: Belongs to the SFR1/MEI5 family


    Find genes that share domains with SFR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SFR1_HUMAN, Q86XK3
    Function: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous
    recombination

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with SFR1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for SFR1:
     Increased homologous recombina 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SFR1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SFR1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SFR1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SFR1

    miRNA
    Products:
        
    miRTarBase miRNAs that target SFR1:
    hsa-mir-192-5p (MIRT026334), hsa-mir-215-5p (MIRT024791)

    Block miRNA regulation of human, mouse, rat SFR1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SFR1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SFR1
    Predesigned siRNA for gene silencing in human, mouse, rat SFR1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for SFR1

    Clone
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    OriGene clones in human, mouse for SFR1 (see all 11)
    OriGene ORF clones in mouse, rat for SFR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for SFR1
    Sino Biological Human cDNA Clone for SFR1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SFR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFR1

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for SFR1
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SFR1_HUMAN, Q86XK3: Nucleus (By similarity)

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0032798Swi5-Sfr1 complex IDA--

    Find genes that share ontologies with SFR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SFR1
    Interactions:

        Search GeneGlobe Interaction Network for SFR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for SFR1 (Q86XK33 ENSP000003587424) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DTNBP1Q96EV83, ENSP000003416804I2D: score=2 STRING: ENSP00000341680
    CDC5LQ994593, ENSP000003605324I2D: score=1 STRING: ENSP00000360532
    EXOC1Q9NV703, ENSP000003265144I2D: score=1 STRING: ENSP00000326514
    TRAF3IP1Q8TDR03, ENSP000003624244I2D: score=1 STRING: ENSP00000362424
    SWI5ENSP000003166094STRING: ENSP00000316609
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000724double-strand break repair via homologous recombination IMP--

    Find genes that share ontologies with SFR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SFR1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SFR1 gene (2 alternative transcripts): 
    NM_001002759.1  NM_145247.4  

    Unigene Cluster for SFR1:

    SWI5-dependent recombination repair 1
    Hs.93667  [show with all ESTs]
    Unigene Representative Sequence: AK123954
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000463224 ENST00000369729(uc001kxs.3 uc001kxt.3) ENST00000369727(uc001kxu.3)
    ENST00000336358(uc001kxv.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat SFR1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate SFR1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for SFR1
    Predesigned siRNA for gene silencing in human, mouse, rat SFR1
    Clone
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    OriGene clones in human, mouse for SFR1 (see all 11)
    OriGene ORF clones in mouse, rat for SFR1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for SFR1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SFR1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SFR1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for SFR1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat SFR1
      QuantiTect SYBR Green Assays in human, mouse, rat SFR1
      QuantiFast Probe-based Assays in human, mouse, rat SFR1

    Additional mRNA sequence: 

    AK123954.1 AK291184.1 BC020892.2 BC047587.2 BC140835.1 

    4 DOTS entries:

    DT.95141653  DT.101982280  DT.95234896  DT.40118485 

    Selected AceView cDNA sequences (see all 52):

    AI659652 BQ182393 CA412135 BU620322 BM763377 BM756680 NM_145247 NM_001002759 
    BC047587 BQ774652 BM712505 BC043256 BC020892 BI830171 CB111855 BI560891 
    BM673783 BX499179 AK123954 BM766505 H83545 BQ003453 AW274839 AA292659 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for SFR1    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b
    SP1:                                                      
    SP2:              -     -                                 
    SP3:              -     -                                 
    SP4:                                                      


    ECgene alternative splicing isoforms for SFR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SFR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAACTTAG
    SFR1 Expression
    About this image

    SFR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SFR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.93667

    UniProtKB/Swiss-Prot: SFR1_HUMAN, Q86XK3
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SFR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SFR1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sfr11 , 5 SWI5 dependent recombination repair 11, 5 68.35(n)1
    55.76(a)1
      19 (40.41 cM)5
    677881  NM_026377.21  NP_080653.21 
     477317565 
    chicken
    (Gallus gallus)
    Aves SFR11 MEI5 meiotic recombination protein homolog (S. cerevisiae) 61.49(n)
    51.14(a)
      770846  XM_001234167.3  XP_001234168.2 
    lizard
    (Anolis carolinensis)
    Reptilia SFR16
    SWI5-dependent recombination repair 1
    47(a)
    1 ↔ 1
    3(41516183-41520990)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX783865.12   -- 75.12(n)    BX783865.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sfr11 SWI5-dependent recombination repair 1 53.44(n)
    47.94(a)
      568747  NM_001082860.1  NP_001076329.1 


    ENSEMBL Gene Tree for SFR1 (if available)
    TreeFam Gene Tree for SFR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SFR1 gene

    Find genes that share paralogs with SFR1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for SFR1
    PGOHUM00000241420 PGOHUM00000241518


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SFR1 (see all 157)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1863693921,2
    C--105879995(+) ATTCTA/GCTTTT 2 -- us2k10--------
    rs1445580511,2
    --105880065(+) GACCTG/TCAGCT 2 -- us2k10--------
    rs122578961,2
    C,F--105880148(+) ACTTAT/CGTAAT 2 -- us2k1 tfbs32Minor allele frequency- C:0.30WA 120
    rs1174390591,2
    F--105880384(+) ACTACT/CGAGTG 2 -- us2k11Minor allele frequency- C:0.01NA 120
    rs1916863621,2
    --105880417(+) TCCAGC/TTGCCT 2 -- us2k10--------
    rs746107201,2
    C--105880420(+) AGCTGC/TCTCTC 2 -- us2k11Minor allele frequency- T:0.01EA 120
    rs1480277331,2
    C--105880540(+) ACAATC/TTGACT 2 -- us2k10--------
    rs1142256071,2
    C,F--105880564(+) CCCTAA/GTCATT 2 -- us2k11Minor allele frequency- G:0.03WA 118
    rs733315541,2
    C,F--105880664(+) GTCAGA/CTGTTA 2 -- us2k18Minor allele frequency- C:0.37WA CSA NA EA 367
    rs2016743311,2
    --105880866(+) GGGCG-/CGGGGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for SFR1 (105881816 - 105886143 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SFR1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv831971CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SFR1
    DNA2.0 Custom Variant and Variant Library Synthesis for SFR1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611420    OMIM disorders: --


    Find genes that share disorders with SFR1           About GenesLikeMe


    Export disorders for SFR1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SFR1 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with SFR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The role of human SWI5-MEI5 complex in homologous recombination repair. (PubMed id 21252223)1, 2, 3 Yuan J. and Chen J. (J. Biol. Chem. 2011)
    2. The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination. (PubMed id 21779174)1, 3 Qing Y....Takeda S. (PLoS Genet. 2011)
    3. Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. (PubMed id 20976249)1, 3 Akamatsu Y. and Jasin M. (PLoS Genet. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    6. Genome-Wide Association Study of Pre-Eclampsia Detects Novel Maternal Single Nucleotide Polymorphisms and Copy-Number Variants in Subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cohort. (PubMed id 23551011)1 Zhao L....Dewan A.T. (Ann. Hum. Genet. 2013)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. (PubMed id 23874500)1 Feng Y....Khan S. (PLoS ONE 2013)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 119392 HGNC: 29574 AceView: C10orf78 Ensembl:ENSG00000156384 euGenes: HUgn119392
    ECgene: SFR1 H-InvDB: SFR1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SFR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for SFR1 gene:
    Search GeneIP for patents involving SFR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     EMD Millipore genomic analysis products

      
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for SFR1  
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     Block miRNA regulation of human, mouse, rat SFR1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing SFR1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SFR1 Predesigned siRNA for gene silencing in human, mouse, rat SFR1
     QuantiFast Probe-based Assays in human, mouse, rat SFR1 QuantiTect SYBR Green Assays in human, mouse, rat SFR1
     Custom PCR Arrays for SFR1 Search Chromatin IP Primers for SFR1
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat SFR1 Search GeneGlobe Interaction Network for SFR1
     Search Regulatory tfbs for SFR1
     GenScript Custom Purified and Recombinant Proteins Services for SFR1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for SFR1
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     Search Tocris compounds for SFR1
     Browse Sino Biological Proteins
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Search for Antibodies for SFR1 at Abcam
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     Browse Proteins at Cloud-Clone Corp.
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     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for SFR1
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     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SFR1
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     LSBio Antibodies in human, mouse, rat for SFR1
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     Browse compounds at ApexBio
     Search Addgene for plasmids for SFR1
      Search eBioscience for proteins for SFR1
      Search eBioscience for elisas for SFR1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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