SF3B3 Gene
protein-coding GIFtS: 62
GCID: GC16P070557
|
|
splicing factor 3b, subunit 3, 130kDa(Previous names: splicing factor 3b, subunit 3, 130kD )
| |
Aliases
for SF3B3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Splicing Factor 3b, Subunit 3, 130kDa1 2 | | STAF1302 3 | | SAP1301 2 3 5 | | SAP 1302 3 | | SF3b1301 2 3 | | Splicing Factor 3b, Subunit 3, 130kD1 | | RSE11 2 | | Pre-MRNA Splicing Factor SF3b, 130 KDa Subunit2 | | KIAA00171 3 | | Splicing Factor 3B Subunit 32 | | Pre-MRNA-Splicing Factor SF3b 130 KDa Subunit2 3 | | SF3B1305 | | Spliceosome-Associated Protein 1302 3 | | |
Export aliases for SF3B3 gene to outside databasesPrevious GC identifers: GC16P061259 GC16P070978 GC16P070293 GC16P070333 GC16P069115 GC16P056388 |
Summaries
for SF3B3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SF3B3:
This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicingfactor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor theU2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has alsobeen identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histoneacetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes mayfunction in chromatin modification, transcription, splicing, and DNA repair. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SF3B3_HUMAN, Q15393Function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of thebranch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E'complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class ofnuclear pre-mRNA intron
Gene Wiki entry for SF3B3
|
Genomic Views
for SF3B3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SF3B3 gene promoter:
RFX1 FOXF2 AP-4 XBP-1 POU6F1 (c2) E4BP4 RORalpha2 AREB6 FOXC1 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for SF3B3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SF3B3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22SF3B3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P070557: view genomic region
(about GC identifiers)
Start:
|
70,557,691 bp from pter |
End:
|
70,611,571 bp from pter |
Size:
|
53,881 bases |
Orientation:
|
plus strand |
|
Proteins
for SF3B3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SF3B3_HUMAN, Q15393 (See
protein sequence)Recommended Name: Splicing factor 3B subunit 3 Size: 1217 amino acids; 135577 Da
Subunit: Identified in the spliceosome C complex. Component of the U11/U12 snRNPs that are part of the U12-typespliceosome. Component of splicing factor SF3B which is composed of at least eight subunits; SF3B1/SAP155/SF3B155,SF3B2/SAP145/SF3B145, SF3B3/SAP130/SF3B130, SF3B4/SAP49/SF3B49, SF3B14A, PHF5A/SF3B14B, SF3B10 and SF3B125. SF3Bassociates with the splicing factor SF3A and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex(U2 snRNP). Interaction between SF3B3 and SF3B1 is tighter than the interaction between SF3B3 and SF3B2. Associateswith the STAGA transcription coactivator-HAT complex. Interacts with SUPT3H
Subcellular location: Nucleus
Sequence caution: Sequence=BAA02805.1; Type=Erroneous initiation; Sequence=BAA32662.2; Type=Erroneous initiation;
Secondary accessions: Q6NTI8 Q96GC0 Q9BPY2 Q9UFX7 Q9UJ29Alternative splicing: 3 isoforms: Q15393-1 Q15393-2 Q15393-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SF3B3: NX_Q15393
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15393
SF3B3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_036558.3
ENSEMBL proteins: ENSP00000305790 ENSP00000454308 ENSP00000461236 ENSP00000463359 ENSP00000461342 ENSP00000464126 ENSP00000463253 Reactome Protein details: Q15393
Human Recombinant Protein Products for SF3B3:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
SF3B3 for ontologies About GeneDecksing
SF3B3 Antibody Products:
Assay Products for SF3B3: |
Protein
Domains /
Families
for SF3B3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SF3B3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q15393ProtoNet protein and cluster: Q15393 1 Blocks protein family: IPB004871 CPSF A subunit C-terminal
UniProtKB/Swiss-Prot: SF3B3_HUMAN, Q15393Similarity: Belongs to the RSE1 family |
Function
for SF3B3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: SF3B3_HUMAN, Q15393Function: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of thebranch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E'complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class ofnuclear pre-mRNA intron Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- |
SF3B3 for ontologies About GeneDecksing
Phenotypes:
7 GenomeRNAi human phenotypes for SF3B3:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SF3B3 (NM_012426) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SF3B3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF3B3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF3B3 |
|
Pathways & Interactions
for SF3B3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | mRNA Splicing - Major Pathway | | | 2 | Generic Transcription Pathway | | | 3 | Signal transduction Activin A signaling regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for SF3B3
1  BioSystems Pathway for SF3B3
5/6 
Reactome Pathways for SF3B3 (see all 6)
1 
Kegg Pathway (Kegg details for SF3B3):
SF3B3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SF3B3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/1025 Interacting proteins for SF3B3 (Q153932, 3 ENSP000003057904) via UniProtKB, MINT, STRING, and/or I2D (see all 1025)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SF3B3 for ontologies About GeneDecksing
|
Drugs & Compounds
for SF3B3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SF3B3
Search CenterWatch for drugs/clinical trials and news about SF3B3
|
Transcripts
for SF3B3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SF3B3 gene: NM_012426.4 Unigene Cluster for SF3B3: Splicing factor 3b, subunit 3, 130kDa Hs.514435 [show with all ESTs]Unigene Representative Sequence: NM_01242614 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000302516(uc002ezf.3) ENST00000566095 ENST00000577085 ENST00000567654
ENST00000564899 ENST00000569687 ENST00000572365 ENST00000567635 ENST00000567250
ENST00000568291 ENST00000568539 ENST00000563739 ENST00000562722 ENST00000565990
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SF3B3 (NM_012426) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SF3B3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF3B3 |
Additional cDNA sequence: AJ001443.1 AK001297.1 AK074933.1 AK291768.1 AL110251.1 BC000463.1 BC003146.1 BC009780.1 BC068974.1 D13642.1 D87686.1 24/34 DOTS entries (see all 34): DT.100664337 DT.91726090 DT.219320 DT.100664338 DT.100664336 DT.95162443 DT.92456004 DT.95327493 DT.97823642 DT.100664340 DT.91752651 DT.99961658 DT.100664333 DT.102835122 DT.40193413 DT.75167598 DT.92455989 DT.95325424 DT.100664334 DT.100673181 DT.101956378 DT.101957658 DT.120690605 DT.120690645 24/624 AceView cDNA sequences (see all 624): BQ958437 BU075748 BP363958 CA438007 CD644246 BX481117 CB163399 CA440036 BE261081 BQ049834 AA767940 BQ060681 BE261741 BE271823 BU579718 BQ961497 CB106158 CA431294 BQ691930 BQ446608 BM972050 CD674009 AL041449 AI659451
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SF3B3 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · | 16c | ^ | 17 | ^ | 18a | · |
|---|
|
| SP1: | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 18b | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23a | · | 23b | ^ | 24a | · | 24b | · | 24c | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28a | · | 28b | ^ | 29 | ^ | 30a | · | 30b |
|---|
|
| SP1: | - | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | |
| SP2: | - | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | - | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SF3B3
|
Expression
for SF3B3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SF3B3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCCCAGGTT
About this image
See SF3B3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SF3B3
SOURCE GeneReport for Unigene cluster: Hs.514435
SABiosciences Custom PCR Arrays for SF3B3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SF3B3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SF3B3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SF3B3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SF3B3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF3B3 |
Orthologs
for SF3B3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SF3B3 gene from 9/35 species (see all 35) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Sf3b31 , 5 |
splicing factor 3b, subunit 31, 5 |
90.77(n)1
99.92(a)1 |
|
8 (57.73 cM)5
1019431 NM_133953.21 NP_598714.11
1108104925 |
chicken
(Gallus gallus) |
Aves |
SF3B31 |
splicing factor 3b, subunit 3, 130kDa |
82.74(n)
99.18(a) |
|
415680 XM_001232347.2 XP_001232348.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SF3B36 |
-- |
99(a) |
1 ↔ 1 |
GL343539.1(81838-107999) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.76172 |
Xenopus laevis transcribed sequence with moderate similarity more |
78.62(n) |
|
BU911752.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb81f052 |
Danio rerio mRNA similar to splicing factor 3b, subunit more |
78.85(n) |
|
BC047171.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG139001 , 3 |
mRNA splicing damaged DNA binding3
CG139001 |
75(a)3
66.56(n)1
75.76(a)1 |
|
61D23
380931 NM_167842.11 NP_728546.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
K02F2.33
teg-41 |
Protein TEG-41 |
60(a)3
59.46(n)1
61.67(a)1 |
|
I(6822596-6842468)3
1724061 NM_059552.21 NP_491953.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G552001 |
splicing factor 3B subunit 3 |
59.57(n)
58.77(a) |
|
824686 NM_115378.3 NP_567015.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.178192 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
73.55(n) |
|
AK068480.1 |
ENSEMBL Gene Tree for SF3B3 (if available)
TreeFam Gene Tree for SF3B3 (if available) |
Paralogs
for SF3B3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SF3B3 gene
- DDB12
SF3B3 for paralogs About GeneDecksing
|
Genomic Variants
for SF3B3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SF3B3 (70557691 - 70611571 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SF3B3
1 CNV: 4965 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SF3B3 |
|
Disorders
/ Diseases
for SF3B3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SF3B3 for disorders About GeneDecksing
OMIM gene information: 605592
OMIM disorders: --
2  diseases for SF3B3: About MalaCardswiskott-aldrich syndrome malaria
Human Genome Epidemiology (HuGE) Navigator: SF3B3 (1 document)
Export disorders for SF3B3 gene to outside databases
|
Publications
for SF3B3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SF3B3 gene, integrated from 9 sources (see all 55):
(articles sorted by number of sources associating them with SF3B3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of a protein complex containing spliceosomal proteins saps 49,130,145 and 155. (PubMed id 10490618)1, 2, 3 Das B.K.... Reed R. (1999)
- The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PubMed id 15146077)1, 2 Will C.L.... Luehrmann R. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
- Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. (PubMed id 12234937)1, 2 Will C.L....Luhrmann R. (2002)
- Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage- binding factors in vivo. (PubMed id 11564863)1, 2 Martinez E.... Roeder R.G. (2001)
- The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger. (PubMed id 11438666)1, 2 Gangloff Y.G.... Davidson I. (2001)
- Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1. (PubMed id 7584026)1, 2 Nomura N.... Tabata S. (1994)
- UV-damaged DNA-binding protein in the TFTC complex links DNA damage recognition to nucleosome acetylation. (PubMed id 11406595)1, 9 Brand M....Tora L. (2001)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
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External Searches for SF3B3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing SF3B3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing SF3B3 gene
(According to HUGE)
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Specialized Databases showing SF3B3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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About This Section
| Patent Information for SF3B3 gene:
Search GeneIP for patents involving SF3B3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SF3B3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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| | |  | OriGene Antibodies for SF3B3 | | OriGene shRNA RFP for SF3B3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SF3B3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SF3B3 | | | OriGene Protein Over-expression Lysate for SF3B3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SF3B3 | | OriGene 3'-UTR Clone for SF3B3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF3B3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SF3B3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SF3B3 | | OriGene Custom Protein Services for SF3B3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SF3B3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SF3B3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SF3B3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SF3B3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SF3B3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SF3B3 |
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| | | | Search Tocris compounds for SF3B3 |
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 | | | SF3B3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF3B3 |
|  |  |  |  | | | | ThermoFisher Antibodies for SF3B3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF3B3 |
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