SF1 Gene
protein-coding GIFtS: 54
GCID: GC11M064532
|
|
splicing factor 1(Previous name: zinc finger protein 162 )
(Previous symbol: ZNF162)
| |
Aliases
for SF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Splicing Factor 11 2 | | Transcription Factor ZFM12 3 | | ZFM11 2 3 5 | | Zinc Finger Gene In MEN1 Locus2 3 | | ZNF1621 2 3 5 | | BBP2 3 | | Zinc Finger Protein 1621 2 3 | | D11S6362 5 | | ZCCHC251 2 | | MBBP2 | | Mammalian Branch Point-Binding Protein2 3 | | MBBP2 |
| External Ids: | HGNC: 129501 | Entrez Gene: 75362 | Ensembl: ENSG000001680667 | OMIM: 6015165 | UniProtKB: Q156373 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n409298 | |
Export aliases for SF1 gene to outside databasesPrevious GC identifers: GC11M067047 GC11M066213 GC11M064782 GC11M064307 GC11M064290 GC11M060858
Summaries
for SF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SF1:
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branchpoint sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multipletranscript variants. (provided by RefSeq, May 2010)
UniProtKB/Swiss-Prot: SF01_HUMAN, Q15637Function: Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence(BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
Gene Wiki entry for SF1
|
Genomic Views
for SF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SF1 gene promoter:
AREB6 RFX1 NF-1 Ik-2 Sox9 NF-kappaB1 GATA-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SF1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SF1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13SF1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M064532: view genomic region
(about GC identifiers)
Start:
|
64,532,076 bp from pter |
End:
|
64,546,316 bp from pter |
Size:
|
14,241 bases |
Orientation:
|
minus strand |
|
Proteins
for SF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SF01_HUMAN, Q15637 (See
protein sequence)Recommended Name: Splicing factor 1 Size: 639 amino acids; 68330 Da
Subunit: Binds U2AF2. Interacts with U1 snRNA. Binds EWSR1, FUS and TAF15
Subcellular location: Nucleus
Sequence caution: Sequence=AAH00773.1; Type=Erroneous initiation;
5 PDB 3D structures from  and Proteopedia  for SF1:1K1G (3D)
2M09 (3D)
2M0G (3D)
4FXW (3D)
4FXX (3D)
Secondary accessions: B7Z1Q1 C9JJE2 Q14818 Q14819 Q15913 Q8IY00 Q92744 Q92745 Q969H7 Q9BW01 Q9UEI0Alternative splicing: 7 isoforms: Q15637-1 Q15637-2 Q15637-3 Q15637-4 Q15637-5 Q15637-6 Q15637-7 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SF1: NX_Q15637
Post-translational modifications:
Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated onSer-4631
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15637
SF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001171501.1 NP_001171502.1 NP_004621.2 NP_973724.1 NP_973726.2 NP_973727.1
ENSEMBL proteins: ENSP00000366604 ENSP00000366607 ENSP00000227503 ENSP00000407962 ENSP00000366611 ENSP00000334414 ENSP00000391198 ENSP00000395927 ENSP00000396793 ENSP00000419062 ENSP00000388470 ENSP00000406354 ENSP00000413084
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SF1 for ontologies About GeneDecksing
SF1 Antibody Products:
Assay Products for SF1: |
Protein
Domains /
Families
for SF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SF1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15637ProtoNet protein and cluster: Q15637 3 Blocks protein families: IPB001878 C2HC-type zinc-finger signature IPB004087 KH domain IPB004088 KH
UniProtKB/Swiss-Prot: SF01_HUMAN, Q15637Similarity: Belongs to the BBP/SF1 familySimilarity: Contains 1 CCHC-type zinc fingerSimilarity: Contains 1 KH domain |
Function
for SF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SF01_HUMAN, Q15637Function: Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence(BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SF1 (NM_001192) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SF1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SF1:
Animal Models:
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Sf1):
SF1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Oct4 in Mammalian ESC Pluripotency | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for SF1
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SF1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/80 Interacting proteins for SF1 (Q156372, 3 ENSP000003666074) via UniProtKB, MINT, STRING, and/or I2D (see all 80)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
SF1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SF1 for compounds About GeneDecksing
 Browse Tocris compounds for SF1
4 Novoseek chemical compound relationships for SF1 gene About this table
Search CenterWatch for drugs/clinical trials and news about SF1 / SF01
|
Transcripts
for SF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SF1 gene (6 alternative transcripts): NM_001178030.1 NM_001178031.1 NM_004630.3 NM_201995.2 NM_201997.2 NM_201998.2 Unigene Cluster for SF1: Splicing factor 1 Hs.502829 [show with all ESTs]Unigene Representative Sequence: NM_00463018/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000377387(uc001oaz.2) ENST00000377390(uc010rnn.2 uc001obb.2)
ENST00000227503 ENST00000448404(uc010rnm.2) ENST00000377394 ENST00000334944(uc001oba.2 uc001obd.2 uc001obc.2 uc001obe.2 uc010rno.2)
ENST00000443908 ENST00000413725 ENST00000433274 ENST00000486867 ENST00000477596
ENST00000489544 ENST00000486960 ENST00000496969 ENST00000413951 ENST00000432725
ENST00000482693 ENST00000472725
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SF1 (NM_001192) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SF1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF1 |
Additional cDNA sequence: AK293753.1 AK296237.1 AK299705.1 AK301803.1 BC000773.1 BC008080.2 BC008724.2 BC011657.2 BC020217.1 BC032676.1 BC034451.1 BC038446.1 BC069273.1 D26120.1 EF212249.1 L49345.1 L49380.1 NR_033649.1 NR_033650.1 Y08765.1 Y08766.1 24/35 DOTS entries (see all 35): DT.453245 DT.92052442 DT.92414509 DT.100668574 DT.95175463 DT.100038621 DT.100668569 DT.120757077 DT.405930 DT.100035328 DT.100668580 DT.419484 DT.120757155 DT.95298250 DT.99985032 DT.120757121 DT.99995080 DT.120757081 DT.120757161 DT.100769370 DT.100801676 DT.100861354 DT.95376176 DT.100668581 24/727 AceView cDNA sequences (see all 727): CR615439 BQ887185 CR600558 BM457074 BM912243 BQ057686 C00412 BX367040 BM922454 CB215798 BQ668390 BU784143 BU859533 BM922700 NM_004630 BG109984 AA378830 BF876038 BQ068391 BX096754 AL040803 BQ676937 CA391167 BM562785
GeneLoc Exon Structure
5/20 Alternative Splicing Database (ASD) splice patterns (SP) for SF1 (see all 20) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | - | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | - | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | ^ | 16a | · | 16b | ^ | 17a | · | 17b | ^ | 18a | · | 18b | · | 18c | ^ | 19 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SF1
|
Expression
for SF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SF1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGTGATTCT
About this image
See SF1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SF1
SOURCE GeneReport for Unigene cluster: Hs.502829
UniProtKB/Swiss-Prot: SF01_HUMAN, Q15637Tissue specificity: Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain,liver and heart
SABiosciences Custom PCR Arrays for SF1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SF1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SF1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF1 |
Orthologs
for SF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SF1 gene from 8/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
SF16 |
-- |
65(a) |
1 ↔ 1 |
GL344137.1(37897-57943) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC046717.12 |
-- |
81.21(n) |
|
BC046717.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
sf12 |
Danio rerio cDNA clone IMAGE6791041, containing frame-shift more |
78.36(n) |
|
BC056288.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
SF11 |
Splicing factor 1 |
57.54(n)
56.22(a) |
|
43912 NM_079915.2 NP_524654.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y116A8C.323
sfa-11 |
Protein SFA-11 |
51(a)3
51.38(n)1
47.68(a)1 |
|
IV(17104701-17111138)3
1784861 NM_070632.41 NP_503033.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
MSL51 |
Msl5p |
44.91(n)
40.38(a) |
|
850807 NP_013217.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G513006AT3G329406 |
RNA-binding KH domain-containing protein |
19(a)12(a) |
1 ↔ many1 ↔ many |
5(20848897-20852334) 3(13490945-13493787) |
rice
(Oryza sativa) |
Liliopsida |
-- |
retrotransposon protein, putative, unclassified, e... |
13(a) |
1 ↔ 1 |
8(53040-57330) |
ENSEMBL Gene Tree for SF1 (if available)
TreeFam Gene Tree for SF1 (if available) |
Paralogs
for SF1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SF1 gene
- KHDRBS22 KHDRBS32 KHDRBS12 QKI2
SF1 for paralogs About GeneDecksing
|
Genomic Variants
for SF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SF1 (64532076 - 64546316 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SF1
3 CNVs: 4753 53146 9667 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SF1 |
|
Disorders
/ Diseases
for SF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SF1 for disorders About GeneDecksing
OMIM gene information: 601516
OMIM disorders: --
12  diseases for SF1: About MalaCardsmultiple endocrine neoplasia wermer syndrome malignant mesothelioma pituitary adenoma
renal cell carcinoma adenoma thyroiditis carcinoma
malaria leukemia familial isolated pituitary adenoma gout
1 Novoseek disease relationship for SF1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| multiple endocrine neoplasia type 1 |
63.6 |
2 |
9150722 (1), 9506990 (1) |
Export disorders for SF1 gene to outside databases
|
Publications
for SF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SF1 gene, integrated from 9 sources (see all 84):
(articles sorted by number of sources associating them with SF1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene. (PubMed id 9573336)1, 2, 3, 9 Kramer A....Mulhauser F. (1998)
- Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1). (PubMed id 7912130)1, 2, 3, 9 Toda T.... Imai T. (1994)
- The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription. (PubMed id 9660765)1, 2, 9 Zhang D.... Childs G. (1998)
- Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA. (PubMed id 8752089)1, 2, 9 Arning S.... Kraemer A. (1996)
- Structural basis for recognition of the intron branch site RNA by splicing factor 1. (PubMed id 11691992)1, 2, 9 Liu Z....Sattler M. (2001)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP. (PubMed id 12718882)1, 2 Selenko P.... Sattler M. (2003)
- Large-scale proteomic analysis of the human spliceosome. (PubMed id 12176931)1, 2 Rappsilber J.... Mann M. (2002)
|
External Searches for SF1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SF1 gene
(According to HUGE)
About This Section
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Specialized Databases showing SF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for SF1 gene:
Search GeneIP for patents involving SF1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for SF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SF1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SF1 | | | OriGene Protein Over-expression Lysate for SF1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SF1 | | OriGene 3'-UTR Clone for SF1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SF1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SF1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SF1 | | OriGene Custom Protein Services for SF1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SF1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SF1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SF1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SF1 |
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| | | | Search Tocris compounds for SF1 |
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 | | | SF1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SF1 |
|  |  |  | | | | Search ThermoFisher Antibodies for SF1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SF1 |
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GeneCards Homepage -
Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013
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