Aliases for SEZ6 Gene
External Ids for SEZ6 Gene
Previous GeneCards Identifiers for SEZ6 Gene
The protein encoded by this gene is thought to contain five cysteine-rich motifs that are similar to sushi domains, as well as two domains similar to the amino terminal half of the CUB (for complement C1r/C1s, Uegf, Bmp1) domain. Mutations in this gene have been associated with febrile seizures. [provided by RefSeq, Jul 2016]
GeneCards Summary for SEZ6 Gene
SEZ6 (Seizure Related 6 Homolog) is a Protein Coding gene. Diseases associated with SEZ6 include Chromosome 17Q11.2 Deletion Syndrome, 1.4-Mb and Febrile Seizures. An important paralog of this gene is SEZ6L.
UniProtKB/Swiss-Prot for SEZ6 Gene
May play a role in cell-cell recognition and in neuronal membrane signaling. Seems to be important for the achievement of the necessary balance between dendrite elongation and branching during the elaboration of a complex dendritic arbor. Involved in the development of appropriate excitatory synaptic connectivity (By similarity).