SETX Gene
protein-coding GIFtS: 55
GCID: GC09M135136
|
|
senataxin(Previous names: amyotrophic lateral sclerosis 4, spinocerebellar ataxia,...)
(Previous symbols: ALS4, SCAR1)
| |
Aliases
for SETX gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Senataxin1 | | Amyotrophic Lateral Sclerosis 41 | | ALS41 2 3 5 | | Spinocerebellar Ataxia, Recessive, Non-Friedreich Type 11 | | SCAR11 2 3 5 | | BA479K20.21 | | AOA21 2 5 | | Probable Helicase Senataxin2 | | KIAA06251 3 | | EC 3.6.4.-3 | | Amyotrophic Lateral Sclerosis 4 Protein2 3 | | EC 3.6.18 | | SEN1 Homolog2 3 | | |
Export aliases for SETX gene to outside databasesPrevious GC identifers: GC09M132170 GC09M134129 GC09M104630 |
Summaries
for SETX gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SETX:
This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activityencoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicasedomain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in thisgene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophiclateral sclerosis (ALS4). (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333Function: Probable helicase, which may be involved in RNA maturation (By similarity). Involved in DNA double-strandbreaks damage response generated by oxidative stress
Gene Wiki entry for SETX
|
Genomic Views
for SETX gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_035014.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SETX gene promoter:
ISGF-3 FOXO3 FOXD3 Cdc5 FOXO3b MEF-2A POU2F1 POU2F1a FOXO3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for SETX
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETX |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.13 Ensembl cytogenetic band: 9q34.13 HGNC cytogenetic band: 9q34SETX Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M135136: view genomic region
(about GC identifiers)
Start:
|
135,136,743 bp from pter |
End:
|
135,230,372 bp from pter |
Size:
|
93,630 bases |
Orientation:
|
minus strand |
|
Proteins
for SETX gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333 (See
protein sequence)Recommended Name: Probable helicase senataxin Size: 2677 amino acids; 302880 Da
Subcellular location: Nucleus, nucleoplasm. Nucleus, nucleolus. Cytoplasm. Note=May be detected in the nucleolus onlyin cycling cells (By similarity). Most abundant in the nucleus. Detected in granules. Colocalized in cycling cellswith FBL in the nucleolus
Sequence caution: Sequence=BAA91701.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB14299.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=CAD97857.1;Type=Frameshift; Positions=1626;
Secondary accessions: A2A396 B2RPB2 B5ME16 C9JQ10 O75120 Q3KQX4 Q5JUJ1 Q68DW5 Q6AZD7 Q7Z3J6 Q8WX33Q9H9D1 Q9NVP9Alternative splicing: 3 isoforms: Q7Z333-1 Q7Z333-3 Q7Z333-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SETX: NX_Q7Z333
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z333
4 DME Specific Peptides for SETX (Q7Z333)
SETX Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055861.3
ENSEMBL proteins: ENSP00000224140 ENSP00000409143 ENSP00000361242 ENSP00000376913
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
SETX for ontologies About GeneDecksing
SETX Antibody Products:
Assay Products for SETX: |
Protein
Domains /
Families
for SETX gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SETX for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q7Z333ProtoNet protein and cluster: Q7Z333 UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333Similarity: Belongs to the DNA2/NAM7 helicase family |
Function
for SETX gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333Function: Probable helicase, which may be involved in RNA maturation (By similarity). Involved in DNA double-strandbreaks damage response generated by oxidative stressEnzyme Numbers (IUBMB): EC 3.6.12 EC 3.6.4.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETX (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETX
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SETX (NM_015046) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETX | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETX |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETX |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
SETX for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for SETX:
|
Pathways & Interactions
for SETX gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SETX
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
5/750 Interacting proteins for SETX (Q7Z3332, 3 ENSP000002241404) via UniProtKB, MINT, STRING, and/or I2D (see all 750)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SETX for ontologies About GeneDecksing
|
Drugs & Compounds
for SETX gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SETX for compounds About GeneDecksing
 Browse Tocris compounds for SETX
2 Novoseek chemical compound relationships for SETX gene About this table
Search CenterWatch for drugs/clinical trials and news about SETX
|
Transcripts
for SETX gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SETX gene: NM_015046.5 Unigene Cluster for SETX: Senataxin Hs.460317 [show with all ESTs]Unigene Representative Sequence: NM_0150467 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000224140(uc004cbk.3) ENST00000436441 ENST00000477049 ENST00000464133
ENST00000474172 ENST00000372169(uc004cbj.3) ENST00000393220(uc010mzt.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETX (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETX
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SETX (NM_015046) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETX | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETX |
Additional cDNA sequence: AB014525.2 AK001456.1 AK022902.1 AK024331.1 AK025601.1 AK125448.1 AK226007.1 AK302394.1 AK307608.1 AY362728.1 BC032600.2 BC032622.1 BC078166.1 BC106017.1 BC137350.1 BX537849.1 BX538166.1 CR749249.1 18 DOTS entries: DT.95149009 DT.92439864 DT.454599 DT.121150438 DT.121150483 DT.100784916 DT.95152255 DT.86841179 DT.92439876 DT.92439878 DT.40129268 DT.95148864 DT.95345721 DT.97822805 DT.97823827 DT.121150474 DT.91646793 DT.97783983 24/395 AceView cDNA sequences (see all 395): CA448085 AK025601 AA814618 AA505302 AI290332 AA284334 CA419586 Z45213 BM718142 BF939450 AL046658 AA864908 AA253472 AA962467 CA445491 BQ271780 BM054862 BP871766 AA904455 AA704244 AI333472 AA505301 Z40775 AI248414
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SETX (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22a | · | 22b | ^ | 23 | ^ | 24a | · | 24b | ^ | 25a | · | 25b | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | - | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SETX
|
Expression
for SETX gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SETX expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATTAGAGGT
About this image
See SETX Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SETX
SOURCE GeneReport for Unigene cluster: Hs.460317
UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333Tissue specificity: Highly expressed in skeletal muscle. Expressed in heart, fibroblast, placenta and liver. Weaklyexpressed in brain and lung. Expressed in the cortex of the kidney (highly expressed in tubular epithelial cells butlow expression in the glomerulus)
SABiosciences Custom PCR Arrays for SETX
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETX
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SETX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETX | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETX |
Orthologs
for SETX gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SETX gene from 5/19 species (see all 19) About this table
ENSEMBL Gene Tree for SETX (if available)
TreeFam Gene Tree for SETX (if available) |
Paralogs
for SETX gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SETX gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SETX (135136743 - 135230372 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SETX: --
Human Gene Mutation Database (HGMD): SETX
Locus Specific Mutation Databases (LSDB): SETX
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETX |
|
Disorders
/ Diseases
for SETX gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SETX for disorders About GeneDecksing
OMIM gene information: 608465
OMIM disorders: 606002 602433
UniProtKB/Swiss-Prot: SETX_HUMAN, Q7Z333
Defects in SETX are the cause of spinocerebellar ataxia autosomal recessive type 1 (SCAR1) [MIM:606002]; alsoknown as ataxia-ocular apraxia 2. Spinocerebellar ataxia is a clinically and genetically heterogeneous group ofcerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speechand eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord.SCAR1 is an autosomal recessive form associated with peripheral neuropathy and elevated serum alpha-fetoprotein,immunoglobulins and, less commonly, creatine kinase levels. Some SCAR1 patients manifest oculomotor apraxia Defects in SETX are a cause of amyotrophic lateral sclerosis type 4 (ALS4) [MIM:602433]. ALS4 is a familialform of amyotrophic lateral sclerosis, a neurodegenerative disorder affecting upper and lower motor neurons andresulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiologyof amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. Thedisease is inherited in 5-10% of cases leading to familial forms. ALS4 is a childhood- or adolescent-onset formcharacterized by slow disease progression and the sparing of bulbar and respiratory muscles
20/22  diseases for SETX (see all 22): About MalaCardsamyotrophic lateral sclerosis lateral sclerosis ataxia-ocular apraxia amyotrophic lateral sclerosis (als)
apraxia ataxia oculomotor apraxia spinocerebellar ataxia
splenic marginal zone lymphoma ataxia with oculomotor apraxia type 2 distal hereditary motor neuropathy amyotrophic lateral sclerosis, type 4
friedreich ataxia cerebellar ataxia axonal neuropathy motor neuron disease
ataxia telangiectasia peripheral neuropathy neuropathy tremor
6 diseases from the University of Copenhagen DISEASES database for SETX:Apraxia DOID:4019 Cerebellar ataxia Amyotrophic lateral sclerosis
Friedreich ataxia Ataxia telangiectasia 8 Novoseek disease relationships for SETX gene About this table
GeneTests: SETX
Ataxia with Oculomotor Apraxia 2Amyotrophic Lateral Sclerosis
Human Genome Epidemiology (HuGE) Navigator: SETX (4 documents)
Export disorders for SETX gene to outside databases
|
Publications
for SETX gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SETX gene, integrated from 9 sources (see all 76):
(articles sorted by number of sources associating them with SETX) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- In cis autosomal dominant mutation of Senataxin associated with tremor/ataxia syndrome. (PubMed id 17096168)1, 2, 9 Bassuk A.G....Bennett C.L. (2007)
- Autosomal recessive ataxia with peripheral neuropathy and elevated AFP: novel mutations in SETX. (PubMed id 16717225)1, 2, 9 Asaka T.... Matsushima A. (2006)
- DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). (PubMed id 15106121)1, 2, 9 Chen Y.-Z.... Chance P.F. (2004)
- Senataxin, defective in ataxia oculomotor apraxia type 2, is involved in the defense against oxidative DNA damage. (PubMed id 17562789)1, 2, 9 Suraweera A.... Lavin M.F. (2007)
- Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia- ocular apraxia 2. (PubMed id 14770181)1, 2, 9 Moreira M.-C.... Koenig M. (2004)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for SETX gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SETX gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SETX gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SETX gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SETX | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/SETX |
|
| | |
About This Section
| Patent Information for SETX gene:
Search GeneIP for patents involving SETX
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SETX gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SETX | | OriGene shRNA RFP for SETX | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SETX | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETX | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SETX | | OriGene 3'-UTR Clone for SETX | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETX | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETX | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SETX | | OriGene Custom Protein Services for SETX | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SETX | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETX | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETX | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SETX | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETX | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETX |
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| | | | Search Tocris compounds for SETX |
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 | | | SETX Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETX |
|  |  |  | | | | Search ThermoFisher Antibodies for SETX |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETX |
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