SETMAR Gene
protein-coding GIFtS: 57
GCID: GC03P004344
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|
SET domain and mariner transposase fusion gene
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Aliases
for SETMAR gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SET Domain And Mariner Transposase Fusion Gene1 2 | | Mar12 | | HsMar12 3 | | Histone-Lysine N-Methyltransferase SETMAR2 | | SET Domain And Mariner Transposase Fusion Gene-Containing Protein2 3 | | Metnase3 | | METNASE2 5 | | EC 2.1.1.438 | | Metnase3 | | |
Export aliases for SETMAR gene to outside databasesPrevious GC identifers: GC03P004273 GC03P004336 GC03P004320 |
Summaries
for SETMAR gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SETMAR:
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and aC-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities includingnon-homologous end joining and double strand break repair. The SET domain portion of this protein specificallymethylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organismslack mariner transposase domain. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Jan2013)
UniProtKB/Swiss-Prot: SETMR_HUMAN, Q53H47Function: Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetictranscriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-bindingactivity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNAnicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNA
Gene Wiki entry for SETMAR
|
Genomic Views
for SETMAR gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SETMAR gene promoter:
TBP LHX3b/Lhx3b MyoD LHX3a/Lhx3a AP-4
Other transcription factors
Search SABiosciences Chromatin IP Primers for SETMAR
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETMAR |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p26.1 Ensembl cytogenetic band: 3p26.1 HGNC cytogenetic band: 3p26.2SETMAR Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P004344: view genomic region
(about GC identifiers)
Start:
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4,344,988 bp from pter |
End:
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4,359,251 bp from pter |
Size:
|
14,264 bases |
Orientation:
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plus strand |
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Proteins
for SETMAR gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SETMR_HUMAN, Q53H47 (See
protein sequence)Recommended Name: Histone-lysine N-methyltransferase SETMAR Size: 671 amino acids; 76669 Da
Cofactor: Binds 1 magnesium ion per subunit
Subcellular location: Nucleus (Probable). Chromosome (Probable)
Miscellaneous: The mariner transposase region in only present in primates and appeared 40-58 million years ago, afterthe insertion of a transposon downstream of a preexisting SET gene, followed by the de novo exonization of previouslynon-coding sequence and the creation of a new intron
4 PDB 3D structures from  and Proteopedia  for SETMAR:3BO5 (3D)
3F2K (3D)
3K9J (3D)
3K9K (3D)
Secondary accessions: Q13579 Q1G668 Q96F41Alternative splicing: 2 isoforms: Q53H47-1 Q53H47-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for SETMAR: NX_Q53H47
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q53H47
2 DME Specific Peptides for SETMAR (Q53H47)
SETMAR Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001230652.1 NP_001263254.1 NP_006506.3
ENSEMBL proteins: ENSP00000373354 ENSP00000393044 ENSP00000397463 ENSP00000403000 ENSP00000403145 ENSP00000369673
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SETMAR for ontologies About GeneDecksing
SETMAR Antibody Products:
Assay Products for SETMAR: |
Protein
Domains /
Families
for SETMAR gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SETMAR for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q53H47ProtoNet protein and cluster: Q53H47 2 Blocks protein families: IPB001214 Nuclear protein SET IPB003616 SET-related region
UniProtKB/Swiss-Prot: SETMR_HUMAN, Q53H47Domain: The mariner transposase Hsmar1 region mediates DNA-binding. It has no transposase activity because the activesite contains an Asn in position 610 instead of a Asp residueSimilarity: In the N-terminal section; belongs to the histone-lysine methyltransferase familySimilarity: In the C-terminal section; belongs to the mariner transposase familySimilarity: Contains 1 post-SET domainSimilarity: Contains 1 pre-SET domainSimilarity: Contains 1 SET domain |
Function
for SETMAR gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SETMR_HUMAN, Q53H47Function: Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetictranscriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Has sequence-specific DNA-bindingactivity and recognizes the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element. Has DNAnicking activity. Has in vivo end joining activity and may mediate genomic integration of foreign DNACatalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine +N(6)-methyl-L-lysine-[histone]Enzyme Number (IUBMB): EC 2.1.1.432
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SETMAR (NM_006515) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETMAR | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETMAR |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETMAR |
Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8): About this table
SETMAR for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for SETMAR:
|
Pathways & Interactions
for SETMAR gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lysine degradation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for SETMAR):
SETMAR for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SETMAR
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/9 Interacting proteins for SETMAR (Q53H473 ENSP000003733544) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
SETMAR for ontologies About GeneDecksing
|
Drugs & Compounds
for SETMAR gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SETMAR
2 HMDB Compounds for SETMAR About this table
Search CenterWatch for drugs/clinical trials and news about SETMAR / SETMR
|
Transcripts
for SETMAR gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SETMAR gene (3 alternative transcripts): NM_001243723.1 NM_001276325.1 NM_006515.3 Unigene Cluster for SETMAR: SET domain and mariner transposase fusion gene Hs.475300 [show with all ESTs]Unigene Representative Sequence: AK1229678 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000358065(uc011asp.2 uc011asq.2 uc003bpy.4 uc011asr.2 uc010hbx.3)
ENST00000413809 ENST00000425046 ENST00000430981(uc003bpw.4) ENST00000425863
ENST00000358950 ENST00000490691 ENST00000462115
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SETMAR (NM_006515) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETMAR | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETMAR |
Additional cDNA sequence: AF054989.1 AK122967.1 AK222734.1 AK297865.1 AK302296.1 AK307537.1 AK311418.1 AY952295.1 BC008931.2 BC011635.2 NR_024022.1 U80776.1 9 DOTS entries: DT.408364 DT.203631 DT.120874334 DT.91657404 DT.100692925 DT.95078066 DT.102842711 DT.100802930 DT.434190 24/81 AceView cDNA sequences (see all 81): CA313648 BX388110 CD366647 BU164805 BM677483 BE890511 AL515729 CR600492 AA234618 BX451998 BQ650846 W93323 CD367822 BP377589 BM723028 AA236558 AF054989 BC011635 BC008931 AA972798 BQ651111 AW583590 T16607 BP378351
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for SETMAR (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | · | 5c | · | 5d |
|---|
|
| SP1: | | | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | - | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | - | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SETMAR
|
Expression
for SETMAR gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SETMAR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGCACAACC
About this image
See SETMAR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SETMAR
SOURCE GeneReport for Unigene cluster: Hs.475300
UniProtKB/Swiss-Prot: SETMR_HUMAN, Q53H47Tissue specificity: Widely expressed, with highest expression in placenta and ovary and lowest expression in skeletalmuscle
SABiosciences Custom PCR Arrays for SETMAR
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETMAR
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat SETMAR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETMAR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETMAR | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETMAR |
Orthologs
for SETMAR gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SETMAR gene from 7/19 species (see all 19) About this table
ENSEMBL Gene Tree for SETMAR (if available)
TreeFam Gene Tree for SETMAR (if available) |
Paralogs
for SETMAR gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SETMAR gene
3 SIMAP similar genes for SETMAR using alignment to 7 protein entries: SETMR_HUMAN (see all proteins):BCL7C FP13812 EHMT1
SETMAR for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for SETMAR
PGOHUM00000247563
|
Genomic Variants
for SETMAR gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SETMAR (4344988 - 4359251 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for SETMAR
1 CNV: 3416 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for SETMAR gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SETMAR for disorders About GeneDecksing
OMIM gene information: 609834
OMIM disorders: --
4  diseases for SETMAR: About MalaCardssitus inversus mantle cell lymphoma homocysteine breast cancer
1 disease from the University of Copenhagen DISEASES database for SETMAR:Situs inversus Human Genome Epidemiology (HuGE) Navigator: SETMAR (1 document)
Export disorders for SETMAR gene to outside databases
|
Publications
for SETMAR gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SETMAR gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with SETMAR) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome. (PubMed id 9461395)1, 2, 3 Robertson H.M. and Zumpano K.L. (1997)
- Biochemical characterization of a SET and transposase fusion protein, Metnase: its DNA binding and DNA cleavage activity. (PubMed id 17877369)1, 2 Roman Y.... Lee S.H. (2007)
- The ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends. (PubMed id 17403897)1, 2 Miskey C....Ivics Z. (2007)
- Birth of a chimeric primate gene by capture of the transposase gene from a mobile element. (PubMed id 16672366)1, 2 Cordaux R.... Feschotte C. (2006)
- The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair. (PubMed id 16332963)1, 2 Lee S.-H.... Hromas R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Chk1 phosphorylation of Metnase enhances DNA repair bu t inhibits replication fork restart. (PubMed id 22231448)1 Hromas R....Lee S.H. (2012)
- Biochemical characterization of metnase's endonucleas e activity and its role in NHEJ repair. (PubMed id 21491884)1 Beck B.D....Lee S.H. (2011)
- Methylation of histone H3 lysine 36 enhances DNA repa ir by nonhomologous end-joining. (PubMed id 21187428)1 Fnu S....Hromas R. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
|
External Searches for SETMAR gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SETMAR gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SETMAR gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SETMAR gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SETMAR | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SETMAR gene:
Search GeneIP for patents involving SETMAR
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SETMAR gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SETMAR | | OriGene shRNA RFP for SETMAR | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SETMAR | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETMAR | | | OriGene Protein Over-expression Lysate for SETMAR | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SETMAR | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETMAR | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SETMAR | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SETMAR | | OriGene Custom Protein Services for SETMAR | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SETMAR | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETMAR | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETMAR | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SETMAR | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETMAR | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETMAR |
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| | | | Search Tocris compounds for SETMAR |
| |  |  |  |  | | | | |
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 | | | SETMAR Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETMAR |
|  |  |  | | | | ThermoFisher Antibodies for SETMAR |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETMAR |
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