SETD7 Gene
protein-coding GIFtS: 64
GCID: GC04M140417
|
|
SET domain containing (lysine methyltransferase) 7
| |
Aliases
for SETD7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| SET Domain Containing (Lysine Methyltransferase) 71 2 | | SET92 3 | | SET71 2 3 5 | | H3-K4-HMTase SETD72 3 | | KMT71 2 3 | | SET Domain-Containing Protein 72 3 | | SET7/91 2 3 | | Set91 | | KIAA17171 3 5 | | Histone H3-Lysine 4-Specific Methyltransferase2 | | Histone H3-K4 Methyltransferase SETD72 3 | | Histone-Lysine N-Methyltransferase SETD72 | | Lysine N-Methyltransferase 72 3 | | EC 2.1.1.433 |
Export aliases for SETD7 gene to outside databasesPrevious GC identifers: GC04M140646 GC04M136156 |
Summaries
for SETD7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: SETD7_HUMAN, Q8WTS6Function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylationrepresents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptionalactivation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading toactivate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, andpossibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10,leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizingp53/TP53 and increasing p53/TP53-mediated transcriptional activation
Gene Wiki entry for SETD7
|
Genomic Views
for SETD7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SETD7 gene promoter:
c-Fos AP-1 ATF-2 SEF-1 (1) Nkx2-5 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for SETD7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETD7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q28 Ensembl cytogenetic band: 4q31.1 HGNC cytogenetic band: 4q31.1SETD7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M140417: view genomic region
(about GC identifiers)
Start:
|
140,417,243 bp from pter |
End:
|
140,477,928 bp from pter |
Size:
|
60,686 bases |
Orientation:
|
minus strand |
|
Proteins
for SETD7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SETD7_HUMAN, Q8WTS6 (See
protein sequence)Recommended Name: Histone-lysine N-methyltransferase SETD7 Size: 366 amino acids; 40721 Da
Subunit: Interacts with IPF1/PDX-1
Subcellular location: Nucleus. Chromosome (Probable)
Miscellaneous: Monomethyltransferase activity is achieved by disrupting the formation at near-attack conformations forthe dimethylation reaction
Sequence caution: Sequence=BAB21808.1; Type=Erroneous initiation;
6/21 PDB 3D structures from  and Proteopedia  for SETD7 (see all 21):1H3I (3D)
1MT6 (3D)
1MUF (3D)
1N6A (3D)
1N6C (3D)
1O9S (3D)
Secondary accessions: B5WWL3 Q0VAH3 Q4W5A9 Q9C0E6Explore the universe of human proteins at neXtProt for SETD7: NX_Q8WTS6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WTS6
SETD7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_085151.1
ENSEMBL proteins: ENSP00000427300 ENSP00000274031 ENSP00000385913 ENSP00000384336
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
SETD7 for ontologies About GeneDecksing
SETD7 Antibody Products:
Assay Products for SETD7: |
Protein
Domains /
Families
for SETD7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SETD7 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8WTS6ProtoNet protein and cluster: Q8WTS6 1 Blocks protein family: IPB001214 Nuclear protein SET
UniProtKB/Swiss-Prot: SETD7_HUMAN, Q8WTS6Domain: The SET domain is necessary but not sufficient for histone methyltransferase activitySimilarity: Belongs to the histone-lysine methyltransferase family. SET7 subfamilySimilarity: Contains 3 MORN repeatsSimilarity: Contains 1 SET domain |
Function
for SETD7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SETD7_HUMAN, Q8WTS6Function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylationrepresents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptionalactivation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading toactivate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, andpossibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10,leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizingp53/TP53 and increasing p53/TP53-mediated transcriptional activationCatalytic activity: S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine +N(6)-methyl-L-lysine-[histone]Biophysicochemical properties: Kinetic parameters: KM=29 uM for histone H3; KM=12 uM for TAF10; KM=69 uM for p53/TP53;Enzyme Number (IUBMB): EC 2.1.1.431
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: SETD7 (NM_030648) | |  | Sino Biological Human cDNA Clone for SETD7 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETD7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETD7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETD7 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
SETD7 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for SETD7:
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Setd7):
SETD7 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SETD7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chromatin Regulation / Acetylation | | | 2 | Selected targets of ESR1 | | | 3 | p53 pathway | | | 4 | Lysine degradation | | | 5 | Signal transduction Activin A signaling regulation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for SETD7
1 
Cell Signaling Technology (CST) Pathway for SETD7
1  BioSystems Pathway for SETD7
1 
Kegg Pathway (Kegg details for SETD7):
SETD7 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SETD7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/59 Interacting proteins for SETD7 (Q8WTS61, 2, 3 ENSP000002740314) via UniProtKB, MINT, STRING, and/or I2D (see all 59)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| HIST1H3B | P684311, 3 | EBI-1268586,EBI-1560041 I2D:
score=2 | | HIST1H3C | P684311, 3 | EBI-1268586,EBI-1560041 I2D:
score=2 | | HIST1H3D | P684311, 3 | EBI-1268586,EBI-1560041 I2D:
score=2 | | HIST1H3E | P684311, 3 | EBI-1268586,EBI-1560041 I2D:
score=2 | | HIST1H3F | P684311, 3 | EBI-1268586,EBI-1560041 I2D:
score=2 |
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
SETD7 for ontologies About GeneDecksing
|
Drugs & Compounds
for SETD7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SETD7 for compounds About GeneDecksing
 Browse Tocris compounds for SETD7
3 HMDB Compounds for SETD7 About this table
1 DrugBank Compound for SETD7 About this table
1 Novoseek chemical compound relationship for SETD7 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lysine |
58.8 |
1 |
19208907 (1), 17646389 (1), 18581285 (1) |
Search CenterWatch for drugs/clinical trials and news about SETD7
|
Transcripts
for SETD7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SETD7 gene: NM_030648.2 Unigene Cluster for SETD7: SET domain containing (lysine methyltransferase) 7 Hs.480792 [show with all ESTs]Unigene Representative Sequence: NM_0306485 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000515101 ENST00000506866 ENST00000274031(uc003ihw.3) ENST00000404104(uc003ihx.3)
ENST00000406354
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SETD7 (NM_030648) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SETD7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETD7 |
Additional cDNA sequence: AB051504.1 AF448510.1 AF462150.1 AK024846.1 AK310856.1 BC012784.2 BC040990.2 BC066361.1 BC110904.1 BC121055.1 BC121056.1 8 DOTS entries: DT.454652 DT.99986131 DT.65288295 DT.95362232 DT.95303625 DT.99938792 DT.121230141 DT.40247526 24/200 AceView cDNA sequences (see all 200): CA421062 CK906166 CA420930 BU899294 BM127273 BU685052 AA485089 CA843084 BF976104 AI272808 BQ008851 BF591520 AA737044 BG151531 BU956500 BQ182263 BP363913 AA888104 AA419512 BF000653 BU522010 AI418884 BE279505 AI094722
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for SETD7 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | - | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for SETD7
|
Expression
for SETD7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SETD7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGCAAGAGA
About this image
See SETD7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SETD7
SOURCE GeneReport for Unigene cluster: Hs.480792
UniProtKB/Swiss-Prot: SETD7_HUMAN, Q8WTS6Tissue specificity: Widely expressed. Expressed in pancreatic islets
SABiosciences Expression via Pathway-Focused PCR Array including SETD7: | Epigenetic Chromatin Modification Enzymes in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETD7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SETD7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETD7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETD7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETD7 |
Orthologs
for SETD7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for SETD7 gene from 5/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Setd71 , 5 |
SET domain containing (lysine methyltransferase) 71, 5 |
87.98(n)1
95.36(a)1 |
|
3 (22.50 cM)5
732511 NM_080793.51 NP_542983.31
515153195 |
chicken
(Gallus gallus) |
Aves |
SETD71 |
SET domain containing (lysine methyltransferase) 7 |
80.97(n)
88.25(a) |
|
422443 XM_420409.3 XP_420409.2 |
lizard
(Anolis carolinensis) |
Reptilia |
SETD76 |
-- |
86(a) |
1 ↔ 1 |
5(120217868-120227342) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.156872 |
Transcribed sequence with moderate similarity to protein more |
77.52(n) |
|
BX732798.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.128762 |
Transcribed sequence with moderate similarity to protein more |
74.98(n) |
|
BM534461.1 |
ENSEMBL Gene Tree for SETD7 (if available)
TreeFam Gene Tree for SETD7 (if available) |
Paralogs
for SETD7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for SETD7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for SETD7
1 CNV: 4418
2 Indels: 68814 59171 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETD7 |
|
Disorders
/ Diseases
for SETD7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SETD7 for disorders About GeneDecksing
OMIM gene information: 606594
OMIM disorders: --
6  diseases for SETD7: About MalaCardsacute leukemia hyperglycemia homocysteine leukemia
breast cancer pancreatitis
1 Novoseek disease relationship for SETD7 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leukemia |
56.8 |
4 |
18829457 (1), 19228930 (1), 20236312 (1) |
Human Genome Epidemiology (HuGE) Navigator: SETD7 (1 document)
Export disorders for SETD7 gene to outside databases
|
Publications
for SETD7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SETD7 gene, integrated from 9 sources (see all 71):
(articles sorted by number of sources associating them with SETD7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation. (PubMed id 11850410)1, 2, 3, 9 Nishioka K.... Reinberg D. (2002)
- Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase. (PubMed id 11779497)1, 2, 3, 9 Wang H....Zhang Y. (2001)
- Repression of p53 activity by Smyd2-mediated methylation. (PubMed id 17108971)1, 2 Huang J.... Berger S.L. (2006)
- Structural basis for the methylation site specificity of SET7/9. (PubMed id 16415881)1, 2 Couture J.-F.... Trievel R.C. (2006)
- Regulation of p53 activity through lysine methylation. (PubMed id 15525938)1, 2 Chuikov S....Reinberg D. (2004)
- Gene-specific modulation of TAF10 function by SET9-mediated methylation. (PubMed id 15099517)1, 2 Kouskouti A....Talianidis I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Structure and catalytic mechanism of the human histone methyltransferase SET7/9. (PubMed id 12540855)1, 2 Xiao B.... Gamblin S.J. (2003)
- Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. (PubMed id 12514135)1, 2 Kwon T.... Cho Y. (2003)
- The active site of the SET domain is constructed on a knot. (PubMed id 12389038)1, 2 Jacobs S.A....Khorasanizadeh S. (2002)
|
External Searches for SETD7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SETD7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SETD7 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SETD7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SETD7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SETD7 gene:
Search GeneIP for patents involving SETD7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SETD7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SETD7 | | OriGene shRNA RFP for SETD7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SETD7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SETD7 | | | OriGene Protein Over-expression Lysate for SETD7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SETD7 | | OriGene 3'-UTR Clone for SETD7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SETD7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SETD7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SETD7 | | OriGene Custom Protein Services for SETD7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SETD7 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETD7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETD7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SETD7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETD7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETD7 |
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| | Antibodies & Assays for SETD7 |
| | | | Search Tocris compounds for SETD7 |
| |  |  |  |  | | | | | | Recombinant Protein for SETD7 |
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 | | | SETD7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETD7 |
|  |  |  | | | | ThermoFisher Antibody for SETD7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SETD7 |
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