External Ids for SETD6 Gene
Previous GeneCards Identifiers for SETD6 Gene
GeneCards Summary for SETD6 Gene
SETD6 (SET Domain Containing 6) is a Protein Coding gene. GO annotations related to this gene include NF-kappaB binding and protein-lysine N-methyltransferase activity.
UniProtKB/Swiss-Prot for SETD6 Gene
Protein-lysine N-methyltransferase. Monomethylates Lys-310 of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity (PubMed:21131967). Monomethylates Lys-8 of H2AZ (H2AZK8me1) (PubMed:23324626). Required for the maintenance of embryonic stem cell self-renewal (By similarity).