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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SETD5 Gene

protein-coding   GIFtS: 47
GCID: GC03P009439

SET domain containing 5

 Explore 1 disease affiliated with
SETD5 via our new
 Human Malady Compendium 
Biological research products
for SETD5
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
SET Domain Containing 51 2
FLJ107071
SET Domain-Containing Protein 52
KIAA17573

External Ids:    HGNC: 255661   Entrez Gene: 552092   Ensembl: ENSG000001681377   UniProtKB: Q9C0A63   

Export aliases for SETD5 gene to outside databases

Previous GC identifers: GC03P009414 GC03P009376


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  --

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SETD5 gene promoter:
         Egr-3   Sp1   STAT5A   AP-2gamma   CBF-C   c-Ets-1   Egr-2   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SETD5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SETD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3   Ensembl cytogenetic band:  3p25.3   HGNC cytogenetic band: 3p25.3

SETD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SETD5 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P009439:  view genomic region     (about GC identifiers)

Start:
9,439,299 bp from pter      End:
9,520,924 bp from pter
Size:
81,626 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SETD5_HUMAN, Q9C0A6 (See protein sequence)
Recommended Name: SET domain-containing protein 5  
Size: 1442 amino acids; 157515 Da
Sequence caution: Sequence=AAH20956.1; Type=Erroneous initiation; Sequence=BAA91762.1; Type=Erroneous initiation;
Sequence=BAB14903.1; Type=Erroneous initiation; Sequence=BAB15144.1; Type=Erroneous initiation; Sequence=BAB21848.1;
Type=Erroneous initiation;
Secondary accessions: Q6AI17 Q8WUB6 Q9H3X4 Q9H6V7 Q9H7S3 Q9NVI9
Alternative splicing: 3 isoforms:  Q9C0A6-1   Q9C0A6-2   Q9C0A6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SETD5: NX_Q9C0A6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C0A6

  • SETD5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001073986.1  
    ENSEMBL proteins: 
     ENSP00000397076   ENSP00000413786   ENSP00000395959   ENSP00000393221   ENSP00000383939  
     ENSP00000384114   ENSP00000408837   ENSP00000302028   ENSP00000382593   ENSP00000401554  
     ENSP00000399993   ENSP00000385852   ENSP00000384429  

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    Uscn Proteins for SETD5


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    Uscn ELISAs and CLIAs for SETD5


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    SETD5 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001214 SET_dom

    Graphical View of Domain Structure for InterPro Entry Q9C0A6

    ProtoNet protein and cluster: Q9C0A6

    1 Blocks protein family: IPB001214 Nuclear protein SET

    UniProtKB/Swiss-Prot: SETD5_HUMAN, Q9C0A6
    Similarity: Contains 1 SET domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SETD5
    8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate SETD5 (see all 34):
    hsa-miR-607 hsa-miR-29a hsa-miR-25 hsa-miR-30d hsa-miR-105 hsa-miR-1184 hsa-miR-30a hsa-miR-3622b-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETD5

    1 GenomeRNAi human phenotype for SETD5:
     Increased HPV18 LCR reporter a 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SETD5

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/7 Interacting proteins for SETD5 (Q9C0A62, 3 ENSP000003839394) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-66971 I2D: score=5 STRING: ENSP00000311695
    DPPA2Q7Z7J52, 3MINT-66647 I2D: score=4 
    LDOC1O957513, ENSP000003595574I2D: score=1 STRING: ENSP00000359557
    TRAF2Q129333, ENSP000002476684I2D: score=5 STRING: ENSP00000247668
    GATA5ENSP000002529974STRING: ENSP00000252997
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SETD5
    Search CenterWatch for drugs/clinical trials and news about SETD5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SETD5 gene (2 alternative transcripts): 
    NM_001080517.1  NM_018187.2  

    Unigene Cluster for SETD5:

    SET domain containing 5
    Hs.288164  [show with all ESTs]
    Unigene Representative Sequence: NM_001080517
    18/30 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 30):
    ENST00000431285 ENST00000450326 ENST00000463180 ENST00000478475 ENST00000415650
    ENST00000443339(uc003brs.1) ENST00000406341 ENST00000468208 ENST00000407969(uc003brv.3 uc010hck.3 uc003brx.3)
    ENST00000442373 ENST00000302463 ENST00000466172 ENST00000490791 ENST00000493918
    ENST00000399686 ENST00000497213 ENST00000413704 ENST00000466242(uc003brw.1)


    miRNA
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    8/34 QIAGEN miScript miRNA Assays for microRNAs that regulate SETD5 (see all 34):
    hsa-miR-607 hsa-miR-29a hsa-miR-25 hsa-miR-30d hsa-miR-105 hsa-miR-1184 hsa-miR-30a hsa-miR-3622b-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SETD5 (see all 6)
    OriGene shRNA RFP: SETD5
    OriGene siRNA: SETD5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SETD5
    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SETD5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SETD5

    Additional cDNA sequence: 

    AB051544.1 AK001569.1 AK024384.1 AK025478.1 AK091393.1 AK092046.1 AK094975.1 AK127298.1 
    AK289529.1 AL442073.1 BC012558.1 BC020956.1 BX648380.1 CR627408.1 

    24/37 DOTS entries (see all 37):

    DT.95350318  DT.100822442  DT.452334  DT.92068010  DT.97764709  DT.120868852  DT.100037304  DT.102834842 
    DT.95128385  DT.40269771  DT.91660762  DT.120868742  DT.95110206  DT.100037307  DT.100822443  DT.91763374 
    DT.95168535  DT.95168543  DT.95216042  DT.40278194  DT.432162  DT.91763378  DT.95168540  DT.95168542 

    24/280 AceView cDNA sequences (see all 280):

    BP362800 AW662870 BF806157 BE870497 BQ071133 BQ950538 AW069173 BU738409 
    AI521094 AL442073 AI401515 BU789478 BF808131 CF785882 AA322491 AA702125 
    AK001569 H80913 AA022954 BM998638 BM718956 AI148997 AL047440 CA868492 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for SETD5 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b ^
    SP1:                                                  -                                                                       -                                 
    SP2:                                                  -                 -                                                     -                                 
    SP3:                    -                             -                 -                                                     -                                 
    SP4:                    -     -     -                                   -                                                                                       
    SP5:                                                                                                                                                            

    ExUns: 17 ^ 18 ^ 19a · 19b · 19c · 19d ^ 20 ^ 21 ^ 22 ^ 23 ^ 24a · 24b · 24c ^ 25a · 25b ^ 26a · 26b ^ 27
    SP1:                                -     -                                               -           -         
    SP2:                                -     -                                               -           -         
    SP3:                                                                                                            
    SP4:                                                                                                            
    SP5:                                -                                                                           


    ECgene alternative splicing isoforms for SETD5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SETD5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTGCCTGGGA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See SETD5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SETD5

    SOURCE GeneReport for Unigene cluster: Hs.288164
        SABiosciences Expression via Pathway-Focused PCR Array including SETD5: 
              Epigenetic Chromatin Modification Enzymes in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SETD5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SETD5 gene from 7/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Setd51 , 5 SET domain containing 51, 5 92.22(n)1
    94.24(a)1
      6 (52.73 cM)5
    728951  NM_028385.11  NP_082661.11 
     1130773655 
    chicken
    (Gallus gallus)
    Aves SETD51 SET domain containing 5 73.54(n)
    75.64(a)
      416046  XM_003642001.1  XP_003642049.1 
    lizard
    (Anolis carolinensis)
    Reptilia SETD56
    --
    67(a)
    1 ↔ 1
    2(190745848-190781494)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ629956.12   -- 79.47(n)    BJ629956.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BM070595.12   -- 76.09(n)    BM070595.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG90076
    --
    8(a)
    1 → many
    3L(13995227-14013248)
    worm
    (Caenorhabditis elegans)
    Secernentea set-96
    set-266
    (see all 4)
    SET (trithorax/polycomb) domain containing family ...
    SET (trithorax/polycomb) domain containing family ...
    (see all 4)
    8(a)
    8(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    IV(4307752-4317253)
    IV(16647092-16655800)


    ENSEMBL Gene Tree for SETD5 (if available)
    TreeFam Gene Tree for SETD5 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SETD5 gene
    MLL52  
    2 SIMAP similar genes for SETD5 using alignment to 9 protein entries:     SETD5_HUMAN (see all proteins):
    DKFZp686A20205    MLL5

    SETD5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1276 NCBI SNPs in SETD5 are shown (see all 1276    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1178991781,2
    C,F,--9374216(+) TACTAG/AAGGAG 1 -- ut311Minor allele frequency- A:0.03EA 120
    rs2005744081,2
    C--9374480(-) CACTAA/CTTATC 1 -- ut310--------
    rs1810811671,2
    C,--9374716(+) GAGAAA/GCGACT 1 -- ut310--------
    rs1133504511,2
    --9376567(+) CCCCCC/TTCGCC 1 -- us2k12Minor allele frequency- T:0.05CSA WA 120
    rs763765181,2
    F,--9376642(+) GACCCA/GACTCC 1 -- us2k12Minor allele frequency- G:0.05WA EA 238
    rs2016593371,2
    C--9376741(+) CCTTTC/TCCTTG 1 -- us2k10--------
    rs753534921,2
    F,--9377167(+) TGCGTG/CTAAGT 1 -- us2k11Minor allele frequency- C:0.03EA 120
    rs64432371,2
    C,F,A,--9437461(+) ATACTA/GGAGGA 3 -- ut31 us2k1 int111Minor allele frequency- G:0.21NA WA CSA EA 374
    rs1881163291,2
    --9437505(+) TGAGTA/GAGAGT 3 -- ut31 int1 us2k10--------
    rs716269231,2
    C,F,--9437724(+) ATGATAAG/-TAGTG 3 -- ut31 us2k1 int12Minor allele frequency- -:0.50NA CSA 4

    HapMap Linkage Disequilibrium report for SETD5 (9439299 - 9520924 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for SETD5
         1 CNV: 6155
    Human Gene Mutation Database (HGMD): SETD5

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SETD5
    DNA2.0 Custom Variant and Variant Library Synthesis for SETD5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    SETD5 for disorders           About GeneDecksing

    1 disease for SETD5:    About MalaCards
    leukemia


    Export disorders for SETD5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SETD5 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with SETD5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    7. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55209 HGNC: 25566 AceView: FLJ10707 Ensembl:ENSG00000168137 euGenes: HUgn55209
    ECgene: SETD5 H-InvDB: SETD5

    (According to HUGE)
    About This Section
    HUGE: KIAA1757

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SETD5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SETD5 gene:
    Search GeneIP for patents involving SETD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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