Aliases for SETD3 Gene
External Ids for SETD3 Gene
Previous HGNC Symbols for SETD3 Gene
Previous GeneCards Identifiers for SETD3 Gene
GeneCards Summary for SETD3 Gene
SETD3 (SET Domain Containing 3) is a Protein Coding gene. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include transcription coactivator activity and histone methyltransferase activity (H3-K4 specific). An important paralog of this gene is SETD6.
UniProtKB/Swiss-Prot for SETD3 Gene
Histone methyltransferase that methylates Lys-4 and Lys-36 of histone H3 (H3K4me and H3K36me). Acts as a transcriptional activator. Plays an important role in the transcriptional regulation of muscle cell differentiation via interaction with MYOD1.