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Aliases for SERTM1 Gene

Aliases for SERTM1 Gene

  • Serine-Rich And Transmembrane Domain Containing 1 2 3
  • C13orf36 3 4
  • Serine-Rich And Transmembrane Domain-Containing Protein 1 3
  • Serine-Rich And Transmembrane Domain-Containing 1 3
  • Chromosome 13 Open Reading Frame 36 2

External Ids for SERTM1 Gene

Previous Symbols for SERTM1 Gene

  • C13orf36

Summaries for SERTM1 Gene

GeneCards Summary for SERTM1 Gene

SERTM1 (Serine-Rich And Transmembrane Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SERTM1 Gene

Genomics for SERTM1 Gene

Genomic Location for SERTM1 Gene

Start:
36,673,912 bp from pter
End:
36,697,839 bp from pter
Size:
23,928 bases
Orientation:
Plus strand

Genomic View for SERTM1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SERTM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SERTM1 Gene

No data available for Regulatory Elements for SERTM1 Gene

Proteins for SERTM1 Gene

  • Protein details for SERTM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2A2V5-SRTM1_HUMAN
    Recommended name:
    Serine-rich and transmembrane domain-containing protein 1
    Protein Accession:
    A2A2V5
    Secondary Accessions:
    • Q8N469

    Protein attributes for SERTM1 Gene

    Size:
    107 amino acids
    Molecular mass:
    11458 Da
    Quaternary structure:
    No Data Available

neXtProt entry for SERTM1 Gene

Proteomics data for SERTM1 Gene at MOPED

Post-translational modifications for SERTM1 Gene

No Post-translational modifications

Other Protein References for SERTM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for SERTM1 Gene

Domains for SERTM1 Gene

Protein Domains for SERTM1 Gene

ProtoNet:
genes like me logo Genes that share domains with SERTM1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for SERTM1 Gene

Function for SERTM1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for SERTM1 Gene

Localization for SERTM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SERTM1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for SERTM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with SERTM1: view

Pathways for SERTM1 Gene

SuperPathways for SERTM1 Gene

No Data Available

Interacting Proteins for SERTM1 Gene

Gene Ontology (GO) - Biological Process for SERTM1 Gene

None

No data available for Pathways by source for SERTM1 Gene

Transcripts for SERTM1 Gene

mRNA/cDNA for SERTM1 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(20) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for SERTM1 Gene

Serine-rich and transmembrane domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SERTM1 Gene

No ASD Table

Relevant External Links for SERTM1 Gene

GeneLoc Exon Structure for
SERTM1
ECgene alternative splicing isoforms for
SERTM1

Expression for SERTM1 Gene

mRNA expression in normal human tissues for SERTM1 Gene

mRNA differential expression in normal tissues according to GTEx for SERTM1 Gene

This gene is overexpressed in Fallopian Tube (10.0), Cervix - Endocervix (5.0), Cervix - Ectocervix (4.7), and Uterus (4.5).

SOURCE GeneReport for Unigene cluster for SERTM1 Gene Hs.422375

genes like me logo Genes that share expressions with SERTM1: view

Orthologs for SERTM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for SERTM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia SERTM1 36
  • 100 (n)
  • 100 (a)
SERTM1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia SERTM1 36
  • 91.9 (n)
  • 97.2 (a)
SERTM1 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C13ORF36 37
  • 97 (a)
OneToOne
SERTM1 36
  • 92.21 (n)
  • 97.2 (a)
mouse
(Mus musculus)
Mammalia Sertm1 36
  • 84.74 (n)
  • 96.26 (a)
Sertm1 16
Sertm1 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia SERTM1 37
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SERTM1 37
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Sertm1 36
  • 86.29 (n)
  • 96.26 (a)
chicken
(Gallus gallus)
Aves SERTM1 36
  • 78.82 (n)
  • 88.79 (a)
lizard
(Anolis carolinensis)
Reptilia SERTM1 37
  • 83 (a)
OneToOne
Species with no ortholog for SERTM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SERTM1 Gene

ENSEMBL:
Gene Tree for SERTM1 (if available)
TreeFam:
Gene Tree for SERTM1 (if available)

Paralogs for SERTM1 Gene

No data available for Paralogs for SERTM1 Gene

Variants for SERTM1 Gene

Sequence variations from dbSNP and Humsavar for SERTM1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs585469 -- 36,686,511(-) taact(A/G)gttaa intron-variant
rs585839 -- 36,686,570(-) aagta(C/T)gcaca intron-variant
rs594452 -- 36,672,538(+) GCCTT(C/T)ATTTC upstream-variant-2KB
rs601214 -- 36,687,635(-) ATGCA(C/T)AGAAA intron-variant
rs603802 -- 36,695,698(-) ATGAG(C/T)CTACG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for SERTM1 Gene

Variant ID Type Subtype PubMed ID
nsv899993 CNV Gain 21882294
nsv524665 CNV Loss 19592680

Relevant External Links for SERTM1 Gene

HapMap Linkage Disequilibrium report
SERTM1

Disorders for SERTM1 Gene

No disorders were found for SERTM1 Gene.

No data available for UniProtKB/Swiss-Prot for SERTM1 Gene

Publications for SERTM1 Gene

  1. Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PMID: 12107410) Wistow G. … Peterson K. (Mol. Vis. 2002) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for SERTM1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate SERTM1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for SERTM1
    • Block miRNA regulation of SERTM1 using miScript Target Protectors

    Sources for SERTM1 Gene

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