SERTAD4 Gene
protein-coding GIFtS : 40
GCID: GC01 P210406
SERTA domain containing 4
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Aliasesfor SERTAD4 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases SERTA Domain Containing 4 1 2 DJ667H12.21 2 SERTA Domain-Containing Protein 42
Export aliases for SERTAD4 gene to outside databases Previous GC identifers: GC01P207486 GC01P206794 GC01P208472 GC01P181079
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Summariesfor SERTAD4 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor SERTAD4 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_167186.1 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the SERTAD4 gene promoter: RFX1 GATA-3 CUTL1 GATA-1 GATA-2 MEF-2A HFH-1 aMEF-2 Hlf Other transcription factors Search SABiosciences Chromatin IP Primers for SERTAD4 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SERTAD4
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1q32.1-q41 Ensembl cytogenetic band: 1q32.2 HGNC cytogenetic band: 1q32.1-q41 SERTAD4 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P210406: view genomic region
(about GC identifiers )
Start:
210,406,144 bp from pter
End:
210,419,976 bp from pter
Size:
13,833 bases
Orientation:
plus strand
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Proteinsfor SERTAD4 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: SRTD4_HUMAN, Q9NUC0 (See
protein sequence )Recommended Name: SERTA domain-containing protein 4 Size : 356 amino acids; 39348 Da
Secondary accessions : B2RD32Explore the universe of human proteins at neXtProt for SERTAD4: NX_Q9NUC0 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9NUC0 SERTAD4 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_062551.1 ENSEMBL proteins: ENSP00000355979 Human Recombinant Protein Products: SERTAD4 Antibody Products: Assay Products for SERTAD4:
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Protein
Domains / Familiesfor SERTAD4 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
SERTAD4 for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q9NUC0 ProtoNet protein and cluster: Q9NUC0
UniProtKB/Swiss-Prot: SRTD4_HUMAN, Q9NUC0 Similarity : Contains 1 SERTA domain
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Functionfor SERTAD4 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SERTAD4 (NM_019605 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SERTAD4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SERTAD4
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD4
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Pathways & Interactionsfor SERTAD4 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SERTAD4 STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)5/6 Interacting proteins for SERTAD4 (Q9NUC0 3 ENSP00000355979 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 6 )About this table
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Drugs & Compoundsfor SERTAD4 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for SERTAD4 Search CenterWatch for drugs/clinical trials and news about SERTAD4 / SRTD4
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Transcriptsfor SERTAD4 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for SERTAD4 gene: NM_019605.3 Unigene Cluster for SERTAD4:
SERTA domain containing 4 Hs.600545 [show with all ESTs ] Unigene Representative Sequence: BC012083 4 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000367012 (uc001hhy.3 uc009xcw.3 ) ENST00000490620 ENST00000482421 ENST00000483884 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4 (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: SERTAD4 (NM_019605 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SERTAD4 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SERTAD4
Additional cDNA sequence: AK021425.1 AK096381.1 AK315386.1 BC012083.1
7 DOTS entries : DT.106563 DT.309377
DT.101957559 DT.121385021 DT.121385028 DT.121385032 DT.207312 24/75 AceView cDNA sequences (see all 75 ):
BP343253 AA608531 BP375789 AA428505 CK431257 NM_019605 BF476423 BQ181878 CA312169 AI801718 N40495 H89347 AI217755 BF939339 CF529482 AI424293 CA450582 AA953006 BC012083 AI276403 AI420123 CR605084 AI671764 BP342499 GeneLoc Exon Structure 5 Alternative Splicing Database (ASD) splice patterns (SP) for SERTAD4 About this scheme ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 SP1 :     -                   SP2 :     -                   SP3 :                       SP4 :               -   -   -     SP5 :             -          
ECgene alternative splicing isoforms for SERTAD4
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Expression for SERTAD4 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section SERTAD4 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAGAGAAGAA
About this image SERTAD4 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See SERTAD4 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for SERTAD4 SOURCE GeneReport for Unigene cluster: Hs.600545 SABiosciences Custom PCR Arrays for SERTAD4 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SERTAD4Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat SERTAD4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SERTAD4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SERTAD4 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD4
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Orthologsfor SERTAD4 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for SERTAD4 gene from 4/10 species (see all 10 ) About this table
ENSEMBL Gene Tree for SERTAD4 (if available)TreeFam Gene Tree for SERTAD4 (if available)
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Paralogsfor SERTAD4 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for SERTAD4 gene
SERTAD4 for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for SERTAD4 PGOHUM00000261854
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Genomic Variantsfor SERTAD4 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for SERTAD4 (210406144 - 210419976 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for SERTAD4: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SERTAD4
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Disorders
/ Diseasesfor SERTAD4 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor SERTAD4 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for SERTAD4 gene integrated from 9 sources : (articles sorted by number of sources associating them with SERTAD4) Utopia : connect your pdf to the dynamic world of online information
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 , 3 Strausberg R.L....Marra M.A. (2002) Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201) 1 Abdelmohsen K....Gorospe M. (2009) An integrated workflow for charting the human interac tion proteome: insights into the PP2A system. (PubMed id 19156129) 1 Glatter T....Gstaiger M. (2009) The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 2 Gregory S.G.... Bentley D.R. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004)
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External Searches for SERTAD4 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing SERTAD4 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing SERTAD4 gene
(According to HUGE )
About This Section --
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Specialized Databases showing SERTAD4 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for SERTAD4 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for SERTAD4 gene: Search GeneIP for patents involving SERTAD4 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor SERTAD4 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for SERTAD4 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for SERTAD4 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for SERTAD4 OriGene Protein Over-expression Lysate for SERTAD4 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for SERTAD4 OriGene 3'-UTR Clone for SERTAD4 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for SERTAD4 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for SERTAD4 OriGene Custom Protein Services for SERTAD4 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SERTAD4 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing SERTAD4 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat SERTAD4 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat SERTAD4 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat SERTAD4 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat SERTAD4
Search Tocris compounds for SERTAD4
SERTAD4 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD4
Search ThermoFisher Antibodies for SERTAD4
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat SERTAD4
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