Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SERTAD2 Gene

protein-coding GIFtS: 47
GCID: GC02M064770

SERTA Domain Containing 2

Search for SERTAD2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
SERTA Domain Containing 2¹ ²		Sei-2²
Transcriptional Regulator Interacting With The PHS-Bromodomain 2¹ ²		SERTA Domain-Containing Protein 2²
Transcriptional Regulator Interacting With The PHD-Bromodomain 2² ³		KIAA0127³
TRIP-Br2² ³

External Ids:	HGNC: 30784¹	Entrez Gene: 9792²	Ensembl: ENSG00000179833⁷	UniProtKB: Q14140³

Export aliases for SERTAD2 gene to outside databases

Previous GC identifers: GC02M064834 GC02M064592

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SERTAD2 Gene:

SERTAD2 (SERTA domain containing 2) is a protein-coding gene. GO annotations related to this gene include transcription coactivator activity. An important paralog of this gene is CDCA4.

UniProtKB/Swiss-Prot: SRTD2_HUMAN, Q14140

Function: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing

transcription factors (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NT_022184.15 NC_018913.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SERTAD2 gene promoter:
Nkx3-1 Nkx3-1 v4 Olf-1 POU6F1 (c2) Nkx3-1 v1 GATA-1 Evi-1 Nkx3-1 v2 GATA-6 Nkx3-1 v3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SERTAD2 promoter sequence

Search SABiosciences Chromatin IP Primers for SERTAD2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERTAD2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p14 Ensembl cytogenetic band: 2p14 HGNC cytogenetic band: 2p15

SERTAD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERTAD2 gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M064770: view genomic region (about GC identifiers)

Start:	64,858,755 bp from pter	End:	64,977,449 bp from pter
Size:	118,695 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SRTD2_HUMAN, Q14140 (See protein sequence)

Recommended Name: SERTA domain-containing protein 2

Size: 314 amino acids; 33897 Da

Sequence caution: Sequence=BAA09476.2; Type=Erroneous initiation;

Secondary accessions: Q53TS2

Explore the universe of human proteins at neXtProt for SERTAD2: NX_Q14140

Explore proteomics data for SERTAD2 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q14140

SERTAD2 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_055570.1

ENSEMBL proteins:

ENSP00000326933

Human Recombinant Protein Products for SERTAD2:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate for SERTAD2 OriGene Custom MassSpec OriGene Custom Protein Services for SERTAD2
	GenScript Custom Purified and Recombinant Proteins Services for SERTAD2
	Novus Biologicals SERTAD2 Protein Novus Biologicals SERTAD2 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for SERTAD2

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	16098148
GO:0005737	cytoplasm	IDA	16098148

SERTAD2 for ontologies About GeneDecksing

SERTAD2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for SERTAD2
	GenScript Custom Superior Antibodies Services for SERTAD2
	Novus Biologicals SERTAD2 Antibodies
	Abcam antibodies for SERTAD2
	Cloud-Clone Corp. Antibodies for SERTAD2
	Search ThermoFisher Antibodies for SERTAD2
	LSBio Antibodies in human, mouse, rat for SERTAD2

Assay Products for SERTAD2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for SERTAD2
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SERTAD2
	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for SERTAD2 Cloud-Clone Corp. CLIAs for SERTAD2

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro protein domain:

IPR009263 SERTA

Graphical View of Domain Structure for InterPro Entry Q14140

ProtoNet protein and cluster: Q14140

1 Blocks protein domain: IPB009263 SERTA

UniProtKB/Swiss-Prot: SRTD2_HUMAN, Q14140

Similarity: Contains 1 SERTA domain

SERTAD2 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: SRTD2_HUMAN, Q14140

Function: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing

transcription factors (By similarity)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003713	transcription coactivator activity	IEA	--
GO:0005515	protein binding	--	--

SERTAD2 for ontologies About GeneDecksing

Phenotypes:
3 GenomeRNAi human phenotypes for SERTAD2:

Decreased NANOG protein expres

Decreased OCT4 protein express

Decreased POU5F1-GFP protein e

7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Sertad2):

adipose tissue	cellular	growth/size	homeostasis/metabolism	immune system
integument	liver/biliary system

SERTAD2 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for SERTAD2

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SERTAD2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SERTAD2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SERTAD2

miRNA Products:		miRTarBase miRNAs that target SERTAD2: hsa-mir-210 (MIRT003157), hsa-mir-155 (MIRT005095)

		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERTAD2
		8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate SERTAD2 (see all 98):
		hsa-miR-3607-3p hsa-miR-607 hsa-miR-640 hsa-miR-106a hsa-miR-128 hsa-miR-374a hsa-miR-3653 hsa-miR-502-3p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for SERTAD2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERTAD2

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for SERTAD2
			Sirion Biotech Customized adenovirus for overexpression of SERTAD2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for SERTAD2 (see all 6) OriGene ORF clones in mouse, rat for SERTAD2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SERTAD2 (NM_014755)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERTAD2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERTAD2
		Sirion Biotech Customized lentivirus for stable overexpression of SERTAD2 Customized lentivirus expression plasmids for stable overexpression of SERTAD2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SERTAD2
		Search LifeMap BioReagents cell lines for SERTAD2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for SERTAD2

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/10 Interacting proteins for SERTAD2 (Q14140³ ENSP00000326933⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TRIM28	Q13263³, ENSP00000253024⁴	I2D: score=3 STRING: ENSP00000253024
E2F1	Q01094³, ENSP00000345571⁴	I2D: score=2 STRING: ENSP00000345571
CREBBP	Q92793³, ENSP00000262367⁴	I2D: score=2 STRING: ENSP00000262367
TFDP1	Q14186³, ENSP00000364519⁴	I2D: score=2 STRING: ENSP00000364519
KAT2B	Q92831³, ENSP00000263754⁴	I2D: score=1 STRING: ENSP00000263754

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0030308	negative regulation of cell growth	IDA	16098148
GO:0045893	positive regulation of transcription, DNA-dependent	IEA	--

SERTAD2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SERTAD2 (SRTD2)

Search CenterWatch for drugs/clinical trials and news about SERTAD2 / SRTD2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SERTAD2 gene:

NM_014755.2

Unigene Cluster for SERTAD2:

SERTA domain containing 2

Hs.591569 [show with all ESTs]

Unigene Representative Sequence: NM_014755

2 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000313349(uc002sde.2) ENST00000476805

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERTAD2
		8/98 QIAGEN miScript miRNA Assays for microRNAs that regulate SERTAD2 (see all 98):
		hsa-miR-3607-3p hsa-miR-607 hsa-miR-640 hsa-miR-106a hsa-miR-128 hsa-miR-374a hsa-miR-3653 hsa-miR-502-3p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for SERTAD2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERTAD2

Clone Products:		OriGene clones in human, mouse for SERTAD2 (see all 6) OriGene ORF clones in mouse, rat for SERTAD2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: SERTAD2 (NM_014755)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERTAD2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERTAD2
		Sirion Biotech Customized lentivirus for stable overexpression of SERTAD2 Customized lentivirus expression plasmids for stable overexpression of SERTAD2

Primer Products:		OriGene qPCR primer pairs and template standards for SERTAD2 OriGene qSTAR qPCR primer pairs in human, mouse for SERTAD2
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SERTAD2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERTAD2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERTAD2

Additional mRNA sequence:

AK311117.1 BC074788.2 BC074789.2 BC101639.1 BC101641.1 D50917.1

8 DOTS entries:

DT.418700 DT.99982477 DT.87014249 DT.91754772 DT.100060546 DT.100681863 DT.75149815 DT.95366098

24/206 AceView cDNA sequences (see all 206):

BQ014466 W58085 H89759 AI032472 AI075890 AA283647 AI589236 AU134908

AA644291 AI335745 BU150508 BG149922 BP341123 BF061406 BC074789 AI538863

AA902590 H89683 AA810121 BE328016 BC074788 W58099 W03762 AI276657

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SERTAD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

See SERTAD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SERTAD2

SOURCE GeneReport for Unigene cluster: Hs.591569

SABiosciences Custom PCR Arrays for SERTAD2

Primer Products:		OriGene qPCR primer pairs and template standards for SERTAD2 OriGene qSTAR qPCR primer pairs in human, mouse for SERTAD2
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat SERTAD2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERTAD2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERTAD2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for SERTAD2 gene from 5/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Sertad2^{1 , 5}	SERTA domain containing 2^{1, 5}	87.84(n)¹ 88.27(a)¹		11 (13.03 cM)⁵ 58172¹ NM_001038625.1¹ NP_001033714.1¹ 20543253⁵
chicken (Gallus gallus)	Aves	SERTAD2¹	SERTA domain containing 2	80.24(n) 81.41(a)		421276 NM_001031037.1 NP_001026208.1
lizard (Anolis carolinensis)	Reptilia	SERTAD2⁶ --	Uncharacterized protein	80(a) 29(a)	1 ↔ 1 possible ortholog	1(124150447-124151406) 1(3610480-3611334)
African clawed frog (Xenopus laevis)	Amphibia	BJ087056.1²	--	87.72(n)		BJ087056.1
zebrafish (Danio rerio)	Actinopterygii	sertad2b¹	SERTA domain containing 2b	68.51(n) 67.1(a)		368888 NM_212794.1 NP_997959.1

ENSEMBL Gene Tree for SERTAD2 (if available)
TreeFam Gene Tree for SERTAD2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SERTAD2 gene

CDCA4²

SERTAD2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs143091859^1,2	C	--	64616546(+)	`CTTAAC/TGAGAC`	1	--	us2k¹		0	--	--	--	--
rs116368246^1,2	F	--	64858259(+)	`CAAGCG/ATGGAG`	1	--	int¹		1		WA	118
rs180937560^1,2		--	64858278(+)	`TGAAGA/GCAACG`	1	--	int¹		0	--	--	--	--
rs141303211^1,2	C	--	64858632(+)	`ACCAAC/TAGCAC`	1	--	int¹		0	--	--	--	--
rs116991156^1,2	C,F	--	64858885(+)	`GGTTCC/TGATGT`	1	--	ut3¹		1		EA	120
rs112392394^1,2	C	--	64858906(+)	`ATATTC/G/TCATAG`	2	--	ut3¹		1		CSA	1
rs185211366^1,2		--	64859030(+)	`TCGGTC/TATGCG`	1	--	ut3¹		0	--	--	--	--
rs191054324^1,2		--	64859035(+)	`CATGCA/GCACAT`	1	--	ut3¹		0	--	--	--	--
rs144975628^1,2		--	64859042(+)	`ACATAC/TGGCCT`	1	--	ut3¹		0	--	--	--	--
rs183666911^1,2		--	64859239(+)	`GAAGGC/TAACCA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for SERTAD2 (64858755 - 64977449 bp)

Structural Variations
Database of Genomic Variants (DGV) 3 variations for SERTAD2: About this table

Variant ID	Type	Subtype	PubMed ID
nsv820222	CNV	Loss	19587683
nsv2756	CNV	Loss	18451855
nsv7313	OTHER	Inversion	18451855

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERTAD2

DNA2.0 Custom Variant and Variant Library Synthesis for SERTAD2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SERTAD2 for disorders About MalaCards

SERTAD2 for disorders About GeneDecksing

Genetic Association Database (GAD): SERTAD2
Human Genome Epidemiology (HuGE) Navigator: SERTAD2 (1 document)

Export disorders for SERTAD2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SERTAD2 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with SERTAD2)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)^{1, 2, 3} Nagase T....Nomura N. (1995)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (2010)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
TRIP-Br: a novel family of PHD zinc finger- and bromodomain- interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. (PubMed id 11331592)^{1, 3} Hsu S.-I....Bonventre J.V. (2001)
TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors. (PubMed id 19152710)^{1, 9} Cheong J.K....Hsu S.I. (2009)
CRM1-mediated nuclear export is required for 26 S proteasome-dependent degradation of the TRIP-Br2 proto-oncoprotein. (PubMed id 18316374)^{1, 9} Cheong J.K....Hsu S.I. (2008)
Ablation of TRIP-Br2, a regulator of fat lipolysis, th ermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. (PubMed id 23291629)¹ Liew C.W....Kulkarni R.N. (2013)
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)¹ Fox C.S....Borecki I.B. (2012)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 9792	HGNC: 30784	AceView: SERTAD2	Ensembl:ENSG00000179833	euGenes: HUgn9792
ECgene: SERTAD2	H-InvDB: SERTAD2

(According to HUGE)
About This Section

HUGE: KIAA0127

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SERTAD2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for SERTAD2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SERTAD2 gene:
Search GeneIP for patents involving SERTAD2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for SERTAD2
	OriGene qPCR primer pairs and template standards for SERTAD2		OriGene Protein Over-expression Lysate for SERTAD2
	OriGene Custom Mass Spec		OriGene clones in human, mouse for SERTAD2
	OriGene qSTAR qPCR primer pairs in human, mouse for SERTAD2		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for SERTAD2		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for SERTAD2		OriGene Custom Protein Services for SERTAD2

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SERTAD2
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERTAD2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERTAD2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERTAD2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERTAD2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERTAD2

	GenScript Custom Purified and Recombinant Proteins Services for SERTAD2		GenScript cDNA clones with any tag delivered in your preferred vector for SERTAD2
	GenScript Custom Assay Services for SERTAD2		GenScript Custom Superior Antibodies Services for SERTAD2
	GenScript Custom overexpressing Cell Line Services for SERTAD2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in SERTAD2 promoter
	Search Chromatin IP Primers for SERTAD2
	RT² qPCR Primer Assay in human, mouse, rat SERTAD2
	GNC Network for SERTAD2
	SABiosciences Custom PCR Arrays for SERTAD2

Search Tocris compounds for SERTAD2 (SRTD2)

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	SERTAD2 antibodies
	SERTAD2 proteins
	SERTAD2 lysates

	Antibodies for SERTAD2
	See all of Abcam's Antibodies, Kits and Proteins for SERTAD2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for SERTAD2
	Antibodies for SERTAD2
	ELISAs for SERTAD2
	CLIAs for SERTAD2

Search LifeMap BioReagents cell lines for SERTAD2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD2

	Browse SwitchGear 3'UTR luciferase reporter plasmids for SERTAD2
	SwitchGear Promoter luciferase reporter plasmids for SERTAD2

Search ThermoFisher Antibodies for SERTAD2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERTAD2

	inGenious Targeting Laboratory - Custom generated mouse model solutions for SERTAD2
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SERTAD2

Customized:

	lentivirus for stable overexpression of SERTAD2
	lentivirus expression plasmids for stable overexpression of SERTAD2
	adenovirus for overexpression of SERTAD2

LSBio Antibodies in human, mouse, rat for SERTAD2

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SERTAD2 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

SERTAD2 Gene

SERTA Domain Containing 2

Aliases
for SERTAD2 gene

Summaries
for SERTAD2 gene

Genomic Views
for SERTAD2 gene

Proteins
for SERTAD2 gene

Protein Domains /
Families
for SERTAD2 gene

Function
for SERTAD2 gene

Pathways & Interactions
for SERTAD2 gene

Drugs & Compounds
for SERTAD2 gene

Transcripts
for SERTAD2 gene

Expression
for SERTAD2 gene

Orthologs
for SERTAD2 gene

Paralogs
for SERTAD2 gene

Genomic Variants
for SERTAD2 gene

Disorders / Diseases
for SERTAD2 gene

Publications
for SERTAD2 gene

External Searches for SERTAD2 gene

Genome Databases showing SERTAD2 gene

Other Databases showing SERTAD2 gene

Specialized Databases showing SERTAD2 gene

Intellectual Property
for SERTAD2 gene

Products
for SERTAD2 gene

View Random Gene

Advanced Search

Export list of displayed genes

SERTAD2 Gene

SERTA Domain Containing 2

Aliasesfor SERTAD2 gene

Summariesfor SERTAD2 gene

Genomic Viewsfor SERTAD2 gene

Proteinsfor SERTAD2 gene

Protein Domains /Familiesfor SERTAD2 gene

Functionfor SERTAD2 gene

Pathways & Interactionsfor SERTAD2 gene

Drugs & Compoundsfor SERTAD2 gene

Transcriptsfor SERTAD2 gene

Expression for SERTAD2 gene

Orthologsfor SERTAD2 gene

Paralogsfor SERTAD2 gene

Genomic Variantsfor SERTAD2 gene

Disorders / Diseasesfor SERTAD2 gene

Publicationsfor SERTAD2 gene

External Searches for SERTAD2 gene

Genome Databases showing SERTAD2 gene

Other Databases showing SERTAD2 gene

Specialized Databases showing SERTAD2 gene

Intellectual Propertyfor SERTAD2 gene

Productsfor SERTAD2 gene

View Random Gene

Aliases
for SERTAD2 gene

Summaries
for SERTAD2 gene

Genomic Views
for SERTAD2 gene

Proteins
for SERTAD2 gene

Protein Domains /
Families
for SERTAD2 gene

Function
for SERTAD2 gene

Pathways & Interactions
for SERTAD2 gene

Drugs & Compounds
for SERTAD2 gene

Transcripts
for SERTAD2 gene

Expression
for SERTAD2 gene

Orthologs
for SERTAD2 gene

Paralogs
for SERTAD2 gene

Genomic Variants
for SERTAD2 gene

Disorders / Diseases
for SERTAD2 gene

Publications
for SERTAD2 gene

Intellectual Property
for SERTAD2 gene

Products
for SERTAD2 gene