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SERTAD1 Gene

protein-coding   GIFtS: 51
GCID: GC19M040928

SERTA Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
SERTA Domain Containing 11 2     SEI12 3
Transcriptional Regulator Interacting With The PHD-Bromodomain 11 2 3     TRIP-Br12 3
CDK4-Binding Protein P34SEI1 2     CDK4-Binding Protein P34SEI12 3
SEI-12 3     SERTA Domain-Containing Protein 12

External Ids:    HGNC: 179321   Entrez Gene: 299502   Ensembl: ENSG000001970197   UniProtKB: Q9UHV23   

Export aliases for SERTAD1 gene to outside databases

Previous GC identifers: GC19M045621 GC19M045619 GC19M037363


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SERTAD1 Gene:
SERTAD1 (SERTA domain containing 1) is a protein-coding gene. Diseases associated with SERTAD1 include esophageal cancer, and esophagitis.

UniProtKB/Swiss-Prot: SRTD1_HUMAN, Q9UHV2
Function: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or
bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the
activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A

Gene Wiki entry for SERTAD1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the SERTAD1 gene promoter:
         COUP-TF   p53   COUP   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERTAD1 promoter sequence
   Search Chromatin IP Primers for SERTAD1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SERTAD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.1-q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.1-q13.2

SERTAD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERTAD1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M040928:  view genomic region     (about GC identifiers)

Start:
40,927,499 bp from pter      End:
40,931,932 bp from pter
Size:
4,434 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SRTD1_HUMAN, Q9UHV2 (See protein sequence)
Recommended Name: SERTA domain-containing protein 1  
Size: 236 amino acids; 24704 Da
Subunit: Interacts with the PHD-bromodomain of TIF1, TRIM28/TIF1B and p300/CBP. Interacts with E2F1 and TFDP1;
modulates transactivation activity of TFDP1/E2F complexes. Also interacts with CDK4
Developmental stage: Transcript levels remain constant in all phases of the cell cycle. In contrast, protein
levels accumulate at the G1/S phase boundary and decrease progressively through S phase until G2/M phase is
reached
Secondary accessions: Q9BUE7

Explore the universe of human proteins at neXtProt for SERTAD1: NX_Q9UHV2

Post-translational modifications: 

  • Polyubiquitinated, which promotes proteasomal degradation1
  • Modification sites at neXtProt
  • REFSEQ proteins: NP_037508.2  
    ENSEMBL proteins: 
     ENSP00000350633  

    SERTAD1 Human Recombinant Protein Products:

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    ProSpec Recombinant Protein for SERTAD1
    Cloud-Clone Corp. Proteins for SERTAD1

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    Cloud-Clone Corp. CLIAs for SERTAD1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009263 SERTA

    Graphical View of Domain Structure for InterPro Entry Q9UHV2

    ProtoNet protein and cluster: Q9UHV2

    1 Blocks protein domain: IPB009263 SERTA

    UniProtKB/Swiss-Prot: SRTD1_HUMAN, Q9UHV2
    Similarity: Contains 1 SERTA domain


    SERTAD1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SRTD1_HUMAN, Q9UHV2
    Function: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or
    bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the
    activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    SERTAD1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SERTAD1:
     Decreased Hepatitis C virus re 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sertad1):
     cellular  endocrine/exocrine gland  homeostasis/metabolism  mortality/aging  tumorigenesis 

    SERTAD1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Sertad1tm1Srn for SERTAD1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SERTAD1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for SERTAD1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SERTAD1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SERTAD1

    miRNA
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    7 qRT-PCR Assays for microRNAs that regulate SERTAD1:
    hsa-miR-515-5p hsa-miR-1236 hsa-miR-3155 hsa-miR-24 hsa-miR-3155b hsa-miR-519e* hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidSERTAD1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for SERTAD1
    Predesigned siRNA for gene silencing in human, mouse, rat SERTAD1

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    GenScript: all cDNA clones in your preferred vector: SERTAD1 (NM_013376)
    Sino Biological Human cDNA Clone for SERTAD1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERTAD1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERTAD1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    extracellular1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including SERTAD1: 
              Cell Cycle in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for SERTAD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SERTAD1 (Q9UHV21, 2, 3 ENSP000003506334) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATXN7L3Q14CW93, ENSP000003972594I2D: score=2 STRING: ENSP00000397259
    RHOBP627453, ENSP000002722334I2D: score=2 STRING: ENSP00000272233
    CDKN2AQ8N7263, ENSP000003551534I2D: score=1 STRING: ENSP00000355153
    TRIM28Q132633, ENSP000002530244I2D: score=1 STRING: ENSP00000253024
    CREBBPQ927933, ENSP000002623674I2D: score=2 STRING: ENSP00000262367
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity TAS6434876
    GO:0006351transcription, DNA-templated IEA--
    GO:0008284positive regulation of cell proliferation TAS6434876
    GO:0045893positive regulation of transcription, DNA-templated IEA--

    SERTAD1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SERTAD1 (SRTD1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SERTAD1 gene: 
    NM_013376.3  

    Unigene Cluster for SERTAD1:

    SERTA domain containing 1
    Hs.269898  [show with all ESTs]
    Unigene Representative Sequence: AK074652
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000357949(uc002ont.4)
    miRNA
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    Block miRNA regulation of human, mouse, rat SERTAD1 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate SERTAD1:
    hsa-miR-515-5p hsa-miR-1236 hsa-miR-3155 hsa-miR-24 hsa-miR-3155b hsa-miR-519e* hsa-miR-484
    SwitchGear 3'UTR luciferase reporter plasmidSERTAD1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for SERTAD1
    Predesigned siRNA for gene silencing in human, mouse, rat SERTAD1
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    GenScript: all cDNA clones in your preferred vector: SERTAD1 (NM_013376)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERTAD1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for SERTAD1
    OriGene qSTAR qPCR primer pairs in human, mouse for SERTAD1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat SERTAD1
      QuantiTect SYBR Green Assays in human, mouse, rat SERTAD1
      QuantiFast Probe-based Assays in human, mouse, rat SERTAD1

    Additional mRNA sequence: 

    AF117959.1 AF366402.1 AK074652.1 AK222970.1 AK223011.1 BC002670.2 

    2 DOTS entries:

    DT.414100  DT.95316673 

    Selected AceView cDNA sequences (see all 115):

    AK074652 BU538362 BC002670 AA642241 AI955492 AI659129 AA928491 BQ182938 
    CB851800 BU078730 CD364905 BU856974 BU633212 BU537987 BM973302 AA719658 
    AI342377 AW071086 AW957102 BU957131 BQ771685 BM673506 BX101521 BU539198 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SERTAD1 expression in normal human tissues (normalized intensities)      SERTAD1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGTGCTGG
    SERTAD1 Expression
    About this image


    SERTAD1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Peripheral Nervous System (Nervous System)
             Schwann Precursor Cells Peripheral Nerve Domain
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
    SERTAD1 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.269898
        Pathway & Disease-focused RT2 Profiler PCR Array including SERTAD1: 
              Cell Cycle in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERTAD1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for SERTAD1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sertad11 , 5 SERTA domain containing 11, 5 83.33(n)1
    86.44(a)1
      7 (15.91 cM)5
    559421  NM_018820.41  NP_061290.11 
     274869105 
    lizard
    (Anolis carolinensis)
    Reptilia SERTAD16
    SERTA domain containing 1
    51(a)
    1 ↔ 1
    LGf(2157487-2158176)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ059948.12   -- 75.07(n)    BJ059948.1 


    ENSEMBL Gene Tree for SERTAD1 (if available)
    TreeFam Gene Tree for SERTAD1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SERTAD1 (see all 138)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1480697281,2
    --40927911(+) TTAGTC/TGGTCC 1 -- int10--------
    rs1408279661,2
    --40927912(+) TAGTCA/GGTCCC 1 -- int10--------
    rs1869649831,2
    --40927981(+) TGAGCC/TGAAGT 1 -- int10--------
    rs1501409591,2
    --40928012(+) TGGGCA/GACAGA 1 -- int10--------
    rs1996247411,2
    C--40928032(+) TGTCT-/AAAAAA 1 -- int10--------
    rs1914012061,2
    --40928085(+) TTGAGC/TCCAGG 1 -- int10--------
    rs711715751,2
    C--40928171(+) AAAAAA/-AAAAA 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1385608361,2
    --40928235(+) TCTCAC/TCTGTA 1 -- int10--------
    rs41509951,2
    C,F,H--40928262(-) agatcG/Agtagt 1 -- int1 ese320Minor allele frequency- A:0.20NS EA NA WA CSA 1770
    rs41509941,2
    C,F--40928307(-) AGCACG/ATCACT 1 -- int1 ese36Minor allele frequency- A:0.02NS NA CSA WA 434

    HapMap Linkage Disequilibrium report for SERTAD1 (40927499 - 40931932 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SERTAD1:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3867n71CNV Loss21882294
    nsv911709CNV Loss21882294
    nsv833831CNV Loss17160897

    Human Gene Mutation Database (HGMD): SERTAD1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SERTAD1
    DNA2.0 Custom Variant and Variant Library Synthesis for SERTAD1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    5 diseases for SERTAD1:    About MalaCards
    esophageal cancer    esophagitis    ataxia    colorectal cancer
    breast cancer


    SERTAD1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SERTAD1
    Human Genome Epidemiology (HuGE) Navigator: SERTAD1 (2 documents)

    Export disorders for SERTAD1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SERTAD1 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with SERTAD1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI- 1). (PubMed id 10580009)1, 2, 3, 9 Sugimoto M.... Hara E. (Genes Dev. 1999)
    2. CRM1-mediated nuclear export is required for 26 S proteasome-dependent degradation of the TRIP-Br2 proto-oncoprotein. (PubMed id 18316374)1, 2 Cheong J.K....Hsu S.I. (J. Biol. Chem. 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. TRIP-Br: a novel family of PHD zinc finger- and bromodomain- interacting proteins that regulate the transcriptional activity of E2F-1/DP-1. (PubMed id 11331592)1, 2 Hsu S.-I....Bonventre J.V. (EMBO J. 2001)
    5. Acid esterase deficiency: comparison of biochemical findings in infantile and adult forms. (PubMed id 6434876)1, 3 Besley G.T....Lawlor E. (J. Inherit. Metab. Dis. 1984)
    6. Dissection of CDK4-binding and transactivation activities of p34(SEI-1) and comparison between functions of p34(SEI-1) and p16(INK4A). (PubMed id 16201750)1, 9 Li J....Tsai M.D. (Biochemistry 2005)
    7. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    8. Effect of PP2A on p34SEI-1 expression in response to ionizing radiation in MCF-7 human breast cancer cells. (PubMed id 21344158)1 Jung S....Lee M.S. (Int. J. Oncol. 2011)
    9. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    10. p34 (SEI-1) inhibits ROS-induced cell death through suppression of ASK1. (PubMed id 21725208)1 Hong S.W....Lee W.K. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29950 HGNC: 17932 AceView: SERTAD1 Ensembl:ENSG00000197019 euGenes: HUgn29950
    ECgene: SERTAD1 H-InvDB: SERTAD1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SERTAD1 Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/sei1/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SERTAD1 gene:
    Search GeneIP for patents involving SERTAD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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