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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERPINI2 Gene

protein-coding   GIFtS: 57
GCID: GC03M167156

Serpin Peptidase Inhibitor, Clade I (Pancpin), Member 2

(Previous names: serine (or cysteine) proteinase inhibitor, clade I (neuroserpin),...)
(Previous symbol: PI14)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Serpin Peptidase Inhibitor, Clade I (Pancpin), Member 21 2     PANCPIN2
PI141 2 3 5     TSA20042
MEPI2 3 5     Protease Inhibitor 142
Serine (Or Cysteine) Proteinase Inhibitor, Clade I (Neuroserpin), Member 21 2     Serpin I22
Serine (Or Cysteine) Proteinase Inhibitor, Clade I (Pancpin), Member 21 2     PI-143
Myoepithelium-Derived Serine Protease Inhibitor2 3     Pancpin3
Pancreas-Specific Protein TSA20042 3     SERPIN125
Peptidase Inhibitor 142 3     

External Ids:    HGNC: 89451   Entrez Gene: 52762   Ensembl: ENSG000001142047   OMIM: 6055875   UniProtKB: O758303   

Export aliases for SERPINI2 gene to outside databases

Previous GC identifers: GC03M164449 GC03M168213 GC03M168561 GC03M168480 GC03M168642


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SERPINI2 Gene:
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins
function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis,
development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during
pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. (provided
by RefSeq, Jan 2013)

GeneCards Summary for SERPINI2 Gene: 
SERPINI2 (serpin peptidase inhibitor, clade I (pancpin), member 2) is a protein-coding gene. Diseases associated with SERPINI2 include familial encephalopathy with neuroserpin inclusion bodies, and refractive error. GO annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB7.

Gene Wiki entry for SERPINI2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERPINI2 gene promoter:
         E2F-3a   E2F-4   E2F-5   CUTL1   E2F-2   GATA-1   E2F-1   E2F   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERPINI2 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERPINI2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPINI2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q26.1   Ensembl cytogenetic band:  3q26.1   HGNC cytogenetic band: 3q26.1

SERPINI2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINI2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M167156:  view genomic region     (about GC identifiers)

Start:
167,159,577 bp from pter      End:
167,196,792 bp from pter
Size:
37,216 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SPI2_HUMAN, O75830 (See protein sequence)
Recommended Name: Serpin I2 precursor  
Size: 405 amino acids; 46145 Da
Subcellular location: Secreted (Probable)
Sequence caution: Sequence=AAH27859.2; Type=Erroneous initiation;

Explore the universe of human proteins at neXtProt for SERPINI2: NX_O75830

Explore proteomics data for SERPINI2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75830

  • SERPINI2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SERPINI2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001012303.1  NP_006208.1  

    ENSEMBL proteins: 
     ENSP00000420621   ENSP00000417692   ENSP00000419407   ENSP00000417752   ENSP00000419255  
     ENSP00000264677  

    Human Recombinant Protein Products for SERPINI2: 
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    OriGene Custom Protein Services for SERPINI2
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    Novus Biologicals SERPINI2 Protein
    Novus Biologicals SERPINI2 Lysates
    Sino Biological Recombinant Protein for SERPINI2
    Sino Biological Cell Lysate for SERPINI2 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space IEA--

    SERPINI2 for ontologies           About GeneDecksing



    SERPINI2 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SERPIN: Serine (or cysteine) peptidase inhibitors

    3 InterPro protein domains:
     IPR023795 Protease_inhib_I4_serpin_CS
     IPR023796 Serpin_dom
     IPR000215 Serpin_fam

    Graphical View of Domain Structure for InterPro Entry O75830

    ProtoNet protein and cluster: O75830

    1 Blocks protein domain: IPB000215 Serpin

    UniProtKB/Swiss-Prot: SPI2_HUMAN, O75830
    Similarity: Belongs to the serpin family


    SERPINI2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IBA--
    GO:0005515protein binding IPI16189514
         
    SERPINI2 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SERPINI2:
     Increased G2M DNA content, inc  Increased cell death HMECs cel 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Serpini2):
     cellular  digestive/alimentary  endocrine/exocrine gland  growth/size  hematopoietic system 
     immune system  mortality/aging 

    SERPINI2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SERPINI2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SERPINI2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SERPINI2 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERPINI2
    1 QIAGEN miScript miRNA Assays for microRNA that regulate SERPINI2:
    hsa-miR-192*
    SwitchGear 3'UTR luciferase reporter plasmidSERPINI2 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Sino Biological Human cDNA Clone for SERPINI2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERPINI2
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                         Customized lentivirus expression plasmids for stable overexpression of SERPINI2 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPINI2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SERPINI2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5 Interacting proteins for SERPINI2 (O758302, 3 ENSP000002646774) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN1Q9UMX02, 3, ENSP000003655764MINT-67715 I2D: score=6 STRING: ENSP00000365576
    HBP1O603812, 3, ENSP000002225744MINT-2861759 I2D: score=1 STRING: ENSP00000222574
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2861740 I2D: score=3 STRING: ENSP00000357292
    SGTBQ96EQ03I2D: score=1 
    UBQLN2ENSP000003451954STRING: ENSP00000345195
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006928cellular component movement TAS10097100
    GO:0010951negative regulation of endopeptidase activity IBA--
    GO:0030162regulation of proteolysis IBA--

    SERPINI2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERPINI2 (SPI2)

    Search CenterWatch for drugs/clinical trials and news about SERPINI2 / SPI2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SERPINI2 gene (2 alternative transcripts): 
    NM_001012303.2  NM_006217.4  

    Unigene Cluster for SERPINI2:

    Serpin peptidase inhibitor, clade I (pancpin), member 2
    Hs.445555  [show with all ESTs]
    Unigene Representative Sequence: NM_001012303
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000476257 ENST00000461846(uc003fes.1) ENST00000471111 ENST00000495108
    ENST00000466903 ENST00000467583 ENST00000465031 ENST00000264677(uc003fer.1 uc003fet.1)

    miRNA
    Products:
         
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate SERPINI2:
    hsa-miR-192*
    SwitchGear 3'UTR luciferase reporter plasmidSERPINI2 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SERPINI2 (NM_006217)
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                         Customized lentivirus expression plasmids for stable overexpression of SERPINI2 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPINI2
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    Additional mRNA sequence: 

    AB006423.1 AK226025.1 AK293391.1 BC027859.2 

    5 DOTS entries:

    DT.92420101  DT.100755123  DT.99933672  DT.100000999  DT.95159510 

    24/34 AceView cDNA sequences (see all 34):

    BC027859 BX497612 BM091362 NM_006217 BM091057 BX496933 BM353460 CA503150 
    BU580945 BM353733 AL696968 BX497698 BU580484 AB006423 AF130470 BI835563 
    CA772296 CA772010 BX497611 BI834396 BX498583 AI972199 BG192641 BM983763 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERPINI2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTCTGGCTC
    SERPINI2 Expression
    About this image


    See SERPINI2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERPINI2

    SOURCE GeneReport for Unigene cluster: Hs.445555

    UniProtKB/Swiss-Prot: SPI2_HUMAN, O75830
    Tissue specificity: Expressed in pancreas and adipose tissues

        SABiosciences Custom PCR Arrays for SERPINI2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPINI2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for SERPINI2 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Serpini21 , 5 serine (or cysteine) peptidase inhibitor, clade I, more1, 5 81.98(n)1
    75.8(a)1
      3 (33.74 cM)5
    679311  NM_026460.21  NP_080736.21 
     752423705 
    fruit fly
    (Drosophila melanogaster)
    Insecta Spn63 serpin 31(a)
    (best of 5)
      55B7   --
    worm
    (Caenorhabditis elegans)
    Secernentea srp-63 serine protease inhibitor 31(a)
    (best of 3)
      V(7386908-7388670)   --


    ENSEMBL Gene Tree for SERPINI2 (if available)
    TreeFam Gene Tree for SERPINI2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERPINI2 gene
    SERPINB72  SERPINB12  SERPINI12  SERPINB52  SERPINB122  SERPINB22  SERPINB102  SERPINB32  
    SERPINB42  SERPINE22  SERPINB62  SERPINC12  SERPINB92  SERPINE12  SERPINB112  SERPINE32  
    SERPINB132  SERPINB82  
    18/31 SIMAP similar genes for SERPINI2 using alignment to 3 protein entries:     SPI2_HUMAN (see all proteins) (see all similar genes):
    SCCA1    SERPINI1    SERPINB11    SERPINB3    SERPINA5    SERPINB1
    SERPINB5    SERPINB6    SERPINA1    SERPINA3    SERPINA9    SERPINE2
    SCCA2    SERPINA11    SERPINB13    SERPINB7    SERPINE1    SERPINA12

    SERPINI2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/794 SNPs in SERPINI2 are shown (see all 794)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1180402031,2
    F--167159081(+) ATGAAG/CTAATA 2 -- ds50011Minor allele frequency- C:0.01EA 120
    rs1144836031,2
    C,F--167159141(+) TTCAAG/AGGAAG 2 -- ds50011Minor allele frequency- A:0.03NA 120
    rs1867142481,2
    C--167159167(+) CTTTAC/TAGTGC 2 -- ds50010--------
    rs738812161,2
    C,F--167159203(+) GGCTCG/AGTATT 2 -- ds50011Minor allele frequency- A:0.50WA 2
    rs1150411661,2
    C,F--167159209(+) GTATTG/ATAAAA 2 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1165358741,2
    F--167159301(+) TCAGCA/CTTTCT 2 -- ds50011Minor allele frequency- C:0.03NA 120
    rs1810740101,2
    C--167159311(+) TATGTC/TGTGTA 2 -- ds50010--------
    rs771783241,2
    F--167159450(+) TGCAAG/AGAATA 2 -- ds50011Minor allele frequency- A:0.07NA 120
    rs124947031,2
    C,F,H--167159568(+) TAGTCT/GAGTAT 2 -- ds50017Minor allele frequency- G:0.05EA NS WA NA 530
    rs1460101181,2
    C--167159657(+) GAATGC/GTAATA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for SERPINI2 (167159577 - 167196792 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for SERPINI2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv877969CNV Loss21882294


    Human Gene Mutation Database (HGMD): SERPINI2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SERPINI2
    DNA2.0 Custom Variant and Variant Library Synthesis for SERPINI2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605587    OMIM disorders: --

    11 diseases for SERPINI2:    About MalaCards
    familial encephalopathy with neuroserpin inclusion bodies    refractive error    pancreatitis    esophageal adenocarcinoma
    mantle cell lymphoma    pancreatic cancer    chronic lymphocytic leukemia    esophagitis
    adenocarcinoma    breast cancer    leukemia


    SERPINI2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SERPINI2
    Human Genome Epidemiology (HuGE) Navigator: SERPINI2 (1 document)

    Export disorders for SERPINI2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERPINI2 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with SERPINI2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation and characterization of a novel human pancreas-specific gene, pancpin, that is down-regulated in pancreatic cancer cells. (PubMed id 9624529)1, 2, 3, 9 Ozaki K.... Nakamura Y. (1998)
    2. A Large-scale genetic association study of esophageal adenocarcinoma risk. (PubMed id 20453000)1, 4 Liu C.Y....Christiani D.C. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Suppression of breast cancer growth and metastasis by a serpin myoepithelium-derived serine proteinase inhibitor expressed in the mammary myoepithelial cells. (PubMed id 10097100)1, 2 Xiao G....Shi Y.E. (1999)
    5. Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26. (PubMed id 10992299)1, 9 Chang W.S....Wu F.Y. (2000)
    6. Common polymorphisms in the SERPINI2 gene are associat ed with refractive error in the 1958 British Birth Cohort. (PubMed id 22110064)1 Hysi P.G....Rahi J.S. (2012)
    7. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
    8. Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia. (PubMed id 19641524)1 Farfsing A....Pscherer A. (2009)
    9. The role of serpins in the surveillance of the secreto ry pathway. (PubMed id 17668148)1 Ragg H. (2007)
    10. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5276 HGNC: 8945 AceView: SERPINI2 Ensembl:ENSG00000114204 euGenes: HUgn5276
    ECgene: SERPINI2 H-InvDB: SERPINI2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERPINI2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SERPINI2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SERPINI2 gene:
    Search GeneIP for patents involving SERPINI2

    GeneCards and IP:
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