SERPIND1 Gene
protein-coding GIFtS: 57
GCID: GC22P021139
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|
serpin peptidase inhibitor, clade D (heparin cofactor),...(Previous names: serine (or cysteine) proteinase inhibitor, clade D (heparin...)
(Previous symbol: HCF2)
| |
Aliases
for SERPIND1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 11 2 | | Serpin D12 3 | | HCF21 2 3 5 | | HCII2 | | HLS21 2 3 | | LS22 | | HC21 2 5 | | THPH102 | | D22S6731 2 | | Heparin Cofactor 22 | | Serine (Or Cysteine) Proteinase Inhibitor, Clade D (Heparin Cofactor), Member 11 2 | | Leuserpin 22 | | HC-II1 3 | | Heparin Cofactor II3 | | Protease Inhibitor Leuserpin-22 3 | | |
Export aliases for SERPIND1 gene to outside databasesPrevious GC identifers: GC22P017827 GC22P019452 GC22P004396 |
Summaries
for SERPIND1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SERPIND1:
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence ofdermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology withantithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated withheparin cofactor II deficiency. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: HEP2_HUMAN, P05546Function: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of thelatter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibitschymotrypsin, but in a glycosaminoglycan-independent mannerFunction: Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils
Gene Wiki entry for SERPIND1 (Heparin cofactor II)
|
Genomic Views
for SERPIND1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SERPIND1 gene promoter:
AML1a POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 NF-kappaB GATA-2 GATA-1 FOXJ2 (long isoform) FOXJ2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for SERPIND1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPIND1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.21SERPIND1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P021139: view genomic region
(about GC identifiers)
Start:
|
21,128,167 bp from pter |
End:
|
21,142,008 bp from pter |
Size:
|
13,842 bases |
Orientation:
|
plus strand |
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Proteins
for SERPIND1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: HEP2_HUMAN, P05546 (See
protein sequence)Recommended Name: Heparin cofactor 2 precursor Size: 499 amino acids; 57071 Da
Sequence caution: Sequence=CAG30459.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for SERPIND1:1JMJ (3D)
1JMO (3D)
Secondary accessions: B2RAI1 D3DX34 Q6IBZ5Explore the universe of human proteins at neXtProt for SERPIND1: NX_P05546
Post-translational modifications:
Phosphorylation sites are present in the extracellular medium1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P05546
SERPIND1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000176.2
ENSEMBL proteins: ENSP00000215727 ENSP00000384050
Human Recombinant Protein Products for SERPIND1:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
SERPIND1 for ontologies About GeneDecksing
SERPIND1 Antibody Products:
Assay Products for SERPIND1: |
Protein
Domains /
Families
for SERPIND1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SERPIND1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P05546ProtoNet protein and cluster: P05546 2 Blocks protein families: IPB000215 Serpin IPB000295 Leuserpin 2 signature
UniProtKB/Swiss-Prot: HEP2_HUMAN, P05546Domain: The N-terminal acidic repeat region mediates, in part, the glycosaminoglycan-accelerated thrombin inhibitionSimilarity: Belongs to the serpin family |
Function
for SERPIND1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: HEP2_HUMAN, P05546Function: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of thelatter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibitschymotrypsin, but in a glycosaminoglycan-independent mannerFunction: Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004866 | endopeptidase inhibitor activity |
TAS | 2647747 | | GO:0004867 | serine-type endopeptidase inhibitor activity |
IBA | -- | | GO:0008201 | heparin binding |
IEA | -- |
SERPIND1 for ontologies About GeneDecksing
Phenotypes:
7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Serpind1):
SERPIND1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for SERPIND1: Serpind1tm1Moto Serpind1tm1Toll
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERPIND1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPIND1 |
|
Pathways & Interactions
for SERPIND1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Complement and coagulation cascades | | | 2 | Formation of Fibrin Clot (Clotting Cascade) | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  R&D Systems Pathway for SERPIND1
1  BioSystems Pathway for SERPIND1
1 
Kegg Pathway (Kegg details for SERPIND1):
SERPIND1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SERPIND1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/6 Interacting proteins for SERPIND1 (P055463 ENSP000002157274) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006935 | chemotaxis |
IEA | -- | | GO:0007596 | blood coagulation |
IEA | -- | | GO:0010951 | negative regulation of endopeptidase activity |
IBA | -- | | GO:0030162 | regulation of proteolysis |
IBA | -- |
SERPIND1 for ontologies About GeneDecksing
|
Drugs & Compounds
for SERPIND1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
SERPIND1 for compounds About GeneDecksing
 Browse Tocris compounds for SERPIND1
1 HMDB Compound for SERPIND1 About this table
3 DrugBank Compounds for SERPIND1 About this table
5 Novoseek chemical compound relationships for SERPIND1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| dermatan sulfate |
85.8 |
24 |
1646716 (3), 2122537 (2), 2266131 (1), 1671335 (1) (see all 15) |
| heparin |
78.6 |
70 |
15371417 (6), 10574918 (2), 12361205 (2), 2196322 (2) (see all 39) |
| glycosaminoglycan |
63.3 |
4 |
15371417 (2), 11068038 (1), 9813026 (1) |
| serine |
36 |
5 |
10753952 (1), 11068038 (1), 2196322 (1), 8562924 (1) (see all 5) |
| fibrinogen |
9.25 |
3 |
10650845 (2), 1391957 (1) |
Search CenterWatch for drugs/clinical trials and news about SERPIND1 / HEP2
|
Transcripts
for SERPIND1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SERPIND1 gene: NM_000185.3 Unigene Cluster for SERPIND1: Serpin peptidase inhibitor, clade D (heparin cofactor), member 1 Hs.474270 [show with all ESTs]Unigene Representative Sequence: NM_0001852 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000215727(uc002ztb.1 uc002ztc.2) ENST00000406799
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERPIND1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERPIND1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: SERPIND1 (NM_000185) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SERPIND1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERPIND1 |
Additional cDNA sequence: AK225292.1 AK314200.1 BC035028.2 CR456573.1 M12849.1 X03498.1 11 DOTS entries: DT.446354 DT.86846377 DT.100018305 DT.100801333 DT.100801331 DT.100648881 DT.86846378 DT.100801332 DT.100801334 DT.120667950 DT.120667998 24/122 AceView cDNA sequences (see all 122): H62677 AU076635 T69076 AU103560 CB123012 X03498 H90149 CR593482 BF872817 CB163577 CR456573 H93798 CB155954 AI133384 CB154086 R28922 BI553740 H57704 BX494607 W00805 AV651226 H94657 H58864 BE673652
GeneLoc Exon Structure
|
Expression
for SERPIND1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SERPIND1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTCCCATAC
About this image
See SERPIND1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SERPIND1
SOURCE GeneReport for Unigene cluster: Hs.474270
UniProtKB/Swiss-Prot: HEP2_HUMAN, P05546Tissue specificity: Expressed predominantly in liver. Also present in plasma
SABiosciences Custom PCR Arrays for SERPIND1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SERPIND1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPIND1 |
Orthologs
for SERPIND1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for SERPIND1 gene from 7/19 species (see all 19) About this table
ENSEMBL Gene Tree for SERPIND1 (if available)
TreeFam Gene Tree for SERPIND1 (if available) |
Paralogs
for SERPIND1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SERPIND1 gene
- SERPING12 SERPINA12 SERPINH12 SERPINA102 SERPINA112 SERPINA72 SERPINA122 SERPINA92
- SERPINA52 SERPINF12 SERPINA42 SERPINA32 SERPINA62 SERPINF22
18/23 SIMAP similar genes for SERPIND1 using alignment to 2 protein entries: HEP2_HUMAN (see all proteins)
(see all similar genes):SERPINA9 SERPINB3 SERPINB4 SERPINA3 SERPINA6 SERPINI2
SCCA2 SERPINA1 SERPINB1 SERPINI1 SERPINB11 SERPINB13
SERPINB8 SERPINA7 SERPINA10 SERPINA12 SERPINB7 SERPINC1
SERPIND1 for paralogs About GeneDecksing
|
Genomic Variants
for SERPIND1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SERPIND1 (21128167 - 21142008 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for SERPIND1: --
Human Gene Mutation Database (HGMD): SERPIND1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERPIND1 |
|
Disorders
/ Diseases
for SERPIND1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
SERPIND1 for disorders About GeneDecksing
OMIM gene information: 142360
OMIM disorders: 612356
UniProtKB/Swiss-Prot: HEP2_HUMAN, P05546
Defects in SERPIND1 are the cause of thrombophilia due to heparin cofactor 2 deficiency (THPH10) [MIM:612356].A hemostatic disorder characterized by a tendency to recurrent thrombosis
20  diseases for SERPIND1: About MalaCardsthrombophilia due to heparin cofactor ii deficiency disseminated intravascular coagulation antithrombin iii deficiency dysfibrinogenemia
thrombophilia protein c deficiency myocardial infarction acute myocardial infarction
cerebral infarction thromboembolism lupus erythematosus hemorrhagic disease
laryngitis laryngeal carcinoma cerebritis thrombosis
atherosclerosis carcinoma hepatitis venous thrombosis
6 diseases from the University of Copenhagen DISEASES database for SERPIND1:Thrombophilia Protein C deficiency Laryngeal carcinoma Antithrombin III deficiency
Hemorrhagic disease Vascular disease 6 Novoseek disease relationships for SERPIND1 gene About this table
Human Genome Epidemiology (HuGE) Navigator: SERPIND1 (3 documents)
Export disorders for SERPIND1 gene to outside databases
|
Publications
for SERPIND1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SERPIND1 gene, integrated from 9 sources (see all 91):
(articles sorted by number of sources associating them with SERPIND1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete nucleotide sequence of the gene for human heparin cofactor II and mapping to chromosomal band 22q11. (PubMed id 1671335)1, 2, 3, 9 Herzog R....Tollefsen D.M. (1991)
- The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans. (PubMed id 1939083)1, 2, 9 van Deerlin V.M.D. and Tollefsen D.M. (1991)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis. (PubMed id 15337701)1, 2 Corral J....Vicente V. (2004)
- Characterization of single-nucleotide polymorphisms in coding regions of human genes. (PubMed id 10391209)1, 2 Cargill M....Lander E.S. (1999)
- Leukocyte chemoattractant peptides from the serpin heparin cofactor II. (PubMed id 1985958)1, 2 Church F.C.... Hoffman M. (1991)
- Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II. (PubMed id 2104620)1, 2 Blinder M.A. and Tollefsen D.M. (1990)
- Heparin cofactor IIOslo. Mutation of Arg-189 to His decreases the affinity for dermatan sulfate. (PubMed id 2647747)1, 2 Blinder M.A.... Tollefsen D.M. (1989)
- Structure and expression of the gene coding for the human serpin hLS2. (PubMed id 2841345)1, 2 Ragg H. and Preibisch G. (1988)
|
External Searches for SERPIND1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SERPIND1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SERPIND1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing SERPIND1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for SERPIND1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for SERPIND1 gene:
Search GeneIP for patents involving SERPIND1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SERPIND1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for SERPIND1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERPIND1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SERPIND1 | | | OriGene Protein Over-expression Lysate for SERPIND1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SERPIND1 | | OriGene 3'-UTR Clone for SERPIND1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERPIND1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERPIND1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SERPIND1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERPIND1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPIND1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERPIND1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERPIND1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPIND1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPIND1 |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERPIND1 |
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