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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERPINB8 Gene

protein-coding   GIFtS: 59
GCID: GC18P061637

serpin peptidase inhibitor, clade B (ovalbumin), member...

(Previous names: serine (or cysteine) proteinase inhibitor, clade B (ovalbumin),...)
(Previous symbol: PI8)
 Explore 3 diseases affiliated with
SERPINB8 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SERPINB8    

Aliases
for SERPINB8 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 81 2     Peptidase Inhibitor 82 3
CAP21 2 3 5     PI-82 3
PI81 2 3 5     Protease Inhibitor 8 (Ovalbumin Type)2
Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 81 2     Serpin B82
Cytoplasmic Antiproteinase 22 3     CAP-23

External Ids:    HGNC: 89521   Entrez Gene: 52712   Ensembl: ENSG000001664017   OMIM: 6016975   UniProtKB: P504523   

Export aliases for SERPINB8 gene to outside databases

Previous GC identifers: GC18P061476 GC18P061610 GC18P061422 GC18P059786 GC18P059295 GC18P059788 GC18P058338


Summaries
for SERPINB8 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SERPINB8:
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular
and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor
suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that
consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 (PubMed 2690952)). A critical portion of
the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member
of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high
degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a
serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 (PubMed
9268635)).(supplied by OMIM, Jan 2010)

Gene Wiki entry for SERPINB8


Genomic Views
for SERPINB8 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.1  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERPINB8 gene promoter:
         RP58   POU3F1   NF-E2 p45   Tal-1beta   YY1   E47   MEF-2A   aMEF-2   Msx-1   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SERPINB8 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERPINB8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPINB8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q22.1   Ensembl cytogenetic band:  18q22.1   HGNC cytogenetic band: 18q22.1

SERPINB8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINB8 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P061637:  view genomic region     (about GC identifiers)

Start:
 61,637,159 bp from pter      End:
 61,672,278 bp from pter
Size:
 35,120 bases      Orientation:
 plus strand

Proteins
for SERPINB8 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SPB8_HUMAN, P50452 (See protein sequence)
Recommended Name: Serpin B8  
Size: 374 amino acids; 42767 Da
Subcellular location: Cytoplasm
Secondary accessions: Q7Z2V6 Q8N178
Alternative splicing: 2 isoforms:  P50452-1   P50452-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SERPINB8: NX_P50452

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P50452

    • SERPINB8 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001027018.1  NP_001263419.1  NP_002631.3  NP_942130.1  

    ENSEMBL proteins: 
     ENSP00000381072   ENSP00000381075   ENSP00000414580   ENSP00000393456   ENSP00000295211  
     ENSP00000331368   ENSP00000438328  
    Reactome Protein details: P50452
    Human Recombinant Protein Products: 
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    Novus Biologicals SERPINB8 Protein
    Novus Biologicals SERPINB8 Lysates
    Sino Biological Recombinant Protein for SERPINB8
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SERPINB8

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IDA8530382


    SERPINB8 for ontologies           About GeneDecksing



    SERPINB8 Antibody Products: 
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    Uscn Antibodies for SERPINB8
    Search ThermoFisher Antibodies for SERPINB8

    Assay Products for SERPINB8: 
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    Uscn ELISAs and CLIAs for SERPINB8

    Protein Domains /
    Families
    for SERPINB8 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SERPINB8 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR023795 Protease_inhib_I4_serpin_CS
     IPR023796 Serpin_dom
     IPR000215 Serpin_fam

    Graphical View of Domain Structure for InterPro Entry P50452

    ProtoNet protein and cluster: P50452

    1 Blocks protein family: IPB000215 Serpin

    UniProtKB/Swiss-Prot: SPB8_HUMAN, P50452
    Similarity: Belongs to the serpin family. Ov-serpin subfamily


    Function
    for SERPINB8 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERPINB8
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate SERPINB8:
    hsa-miR-607 hsa-miR-3688-3p hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmid: SERPINB8 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: SERPINB8
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for SERPINB8

    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IDA8530382
    GO:0005515protein binding IPI8530382


    SERPINB8 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SERPINB8:
     Increased G2M DNA content 


    Pathways & Interactions
    for SERPINB8 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF)
    		CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF)1.00
    2Platelet activation, signaling and aggregation
    		Hemostasis0.43
    3Expression of PAI-1
    		Dissolution of Fibrin Clot0.10

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for SERPINB8
        CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF)

    2        Reactome Pathways for SERPINB8
        Hemostasis
    Dissolution of Fibrin Clot



    SERPINB8 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SERPINB8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/7 Interacting proteins for SERPINB8 (P504523 ENSP000003313684) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FURINP099583, ENSP000002681714I2D: score=3 STRING: ENSP00000268171
    BCL2P104153, ENSP000003296234I2D: score=1 STRING: ENSP00000329623
    F2P007343, ENSP000003085414I2D: score=1 STRING: ENSP00000308541
    F10P007423, ENSP000003647094I2D: score=2 STRING: ENSP00000364709
    PRSS1P074773, ENSP000003087204I2D: score=2 STRING: ENSP00000308720
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010951negative regulation of endopeptidase activity IDA8530382
    GO:0030162regulation of proteolysis IBA--


    SERPINB8 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SERPINB8 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERPINB8
    Search CenterWatch for drugs/clinical trials and news about SERPINB8 / SPB8 

    Transcripts
    for SERPINB8 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SERPINB8 gene (4 alternative transcripts): 
    NM_001031848.1  NM_001276490.1  NM_002640.3  NM_198833.1  

    Unigene Cluster for SERPINB8:

    Serpin peptidase inhibitor, clade B (ovalbumin), member 8
    Hs.368077  [show with all ESTs]
    Unigene Representative Sequence: NM_198833
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000397985(uc002lju.3 uc010xex.2) ENST00000397988(uc002ljt.3)
    ENST00000448851 ENST00000441827(uc002ljs.1) ENST00000295211 ENST00000493661
    ENST00000353706(uc002ljv.3) ENST00000542677

    miRNA
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    hsa-miR-607 hsa-miR-3688-3p hsa-miR-616* hsa-miR-373*
    SwitchGear 3'UTR luciferase reporter plasmid: SERPINB8 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: SERPINB8
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPINB8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERPINB8

    Additional cDNA sequence: 

    AK300391.1 AK313782.1 BC034528.1 BX571754.1 DQ656055.2 L40377.1 U92984.1 

    5 DOTS entries:

    DT.209901  DT.95269447  DT.95269448  DT.92004519  DT.303141 

    24/66 AceView cDNA sequences (see all 66):

    BM696260 AL711105 CK904586 AA972628 NM_002640 NM_198833 AA360401 CK904587 
    CF130399 CB122815 BC034528 BX098348 BQ929418 BQ003005 AI095851 BM068728 
    BG499418 AF118928 BX113096 BI819086 BQ435307 AL708543 L40377 AI925897 

    GeneLoc Exon Structure


    Expression
    for SERPINB8 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERPINB8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATTTGTTGAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SERPINB8 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SERPINB8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERPINB8

    SOURCE GeneReport for Unigene cluster: Hs.368077
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    In Situ
    Assay Products:     
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    Orthologs
    for SERPINB8 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for SERPINB8 gene from 4/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves F1P1L8_CHICK6
    		 serine (or cysteine) proteinase inhibitor, clade B...
    		 55(a)
    		 1 → many
    		 2(68854258-68863717)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 49(a)
    		 1 → many
    		 GL343311.1(705019-715600)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BC054232.12   -- 73.33(n)    BC054232.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii serpinb1l16
    serpinb1l36
    (see all 5)    		 serpin peptidase inhibitor, clade B (ovalbumin), m...
    serpin peptidase inhibitor, clade B (ovalbumin), m...
    (see all 5)    		 46(a)
    43(a)
    (see all 5)    		 many ↔ many
    many ↔ many
    (see all 5)    		 16(54874440-54879870)
    24(43916745-43926516)


    ENSEMBL Gene Tree for SERPINB8 (if available)
    TreeFam Gene Tree for SERPINB8 (if available) 

    Paralogs
    for SERPINB8 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERPINB8 gene
    SERPINB72  SERPINB12  SERPINI12  SERPINB52  SERPINB122  SERPINI22  SERPINB22  SERPINB102  
    SERPINB32  SERPINB42  SERPINE22  SERPINB62  SERPINC12  SERPINB92  SERPINE12  SERPINE32  
    SERPINB132  
    18/37 SIMAP similar genes for SERPINB8 using alignment to 5 protein entries:     SPB8_HUMAN (see all proteins) (see all similar genes):
    DKFZp686O07189    SERPINB9    SERPINB6    PLANH2    HMSD    SCCA1
    SERPINB1    SERPINB10    SERPINB3    SERPINB12    SERPINB11    DKFZp686D06190
    SERPINB4    SCCA2    SERPINB5    SERPINC1    SERPINA1    AT3

    SERPINB8 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for SERPINB8
    PGOHUM00000243470


    Genomic Variants
    for SERPINB8 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/435 NCBI SNPs in SERPINB8 are shown (see all 435)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 18 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs744724451,2
    		--61635298(+) CTTTGA/TTTCTT 3 -- us2k12Minor allele frequency- T:0.06NA EA 122
    rs6095441,2
    		H--61635314(-) AGGAAG/CAGGGA 3 -- us2k1 trp34Minor allele frequency- C:0.00NS EA 402
    rs1818598981,2
    		--61635352(+) TTATGC/TCCTGG 3 -- us2k10--------
    rs617445681,2
    		C,F,--61635387(+) TCTCCA/TTTTCT 3 -- us2k13Minor allele frequency- T:0.27NS WA NA 316
    rs1496496761,2
    		--61635430(+) TCTCAC/TCCATG 3 -- us2k10--------
    rs1874110151,2
    		--61635434(+) ATCCAC/TGCTGC 3 -- us2k10--------
    rs1170300631,2
    		--61635485(+) ATATAC/TTCCAT 3 -- us2k11Minor allele frequency- T:0.01NA 120
    rs6086391,2
    		C,H--61635543(-) TTAAGC/TTGGGG 3 -- us2k14Minor allele frequency- T:0.00NS EA 420
    rs1124067251,2
    		--61635584(+) GGGAAT/CGAAGA 3 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1918069561,2
    		--61635696(+) GCCTGA/GATACG 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for SERPINB8 (61637159 - 61672278 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for SERPINB8
         3 CNVs: 88880 88881 67377

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    Disorders / Diseases
    for SERPINB8 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SERPINB8 for disorders           About GeneDecksing

    OMIM gene information: 601697    OMIM disorders: --

    3 diseases for SERPINB8:    About MalaCards
    kimura disease    neuroendocrine tumor    psoriasis

    Human Genome Epidemiology (HuGE) Navigator: SERPINB8 (4 documents)

    Export disorders for SERPINB8 gene to outside databases

    Publications
    for SERPINB8 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERPINB8 gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with SERPINB8)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors. (PubMed id 8530382)1, 2, 3, 9 Sprecher C.A.... Kisiel W. (1995)
    2. Cytoplasmic antiproteinase 2 (PI8) and bomapin (PI10) map to the serpin cluster at 18q21.3. (PubMed id 9268635)1, 3 Bartuski A.J....Silverman G.A. (1997)
    3. Distribution of the human intracellular serpin protease inhibitor 8 in human tissues. (PubMed id 12417609)1, 9 Strik M.C....Kummer J.A. (2002)
    4. Inhibition of soluble recombinant furin by human proteinase inhibitor 8. (PubMed id 9442015)1, 9 Dahlen J.R....Kisiel W. (1998)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. (PubMed id 22837378)1 Wilk J.B....Stricker B.H. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Association analyses identify six new psoriasis susce ptibility loci in the Chinese population. (PubMed id 20953187)1 Sun L.D....Zhang X.J. (2010)

    External Searches for SERPINB8 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    Genome Databases showing SERPINB8 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5271 HGNC: 8952 AceView: SERPINB8 Ensembl:ENSG00000166401 euGenes: HUgn5271
    ECgene: SERPINB8 H-InvDB: SERPINB8

    Other Databases showing SERPINB8 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SERPINB8 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERPINB8 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SERPINB8 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SERPINB8 gene:
    Search GeneIP for patents involving SERPINB8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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