Aliases for SERPINB7 Gene
External Ids for SERPINB7 Gene
Previous GeneCards Identifiers for SERPINB7 Gene
This gene encodes a member of a family of proteins which function as protease inhibitors. Expression of this gene is upregulated in IgA nephropathy and mutations have been found to cause palmoplantar keratoderma, Nagashima type. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
GeneCards Summary for SERPINB7 Gene
SERPINB7 (Serpin Family B Member 7) is a Protein Coding gene. Diseases associated with SERPINB7 include Palmoplantar Keratoderma, Nagashima Type and Palmoplantar Keratosis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINC1.
UniProtKB/Swiss-Prot for SERPINB7 Gene
Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin.