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SERPINB7 Gene

protein-coding   GIFtS: 52
GCID: GC18P061394

Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member...

(Previous names: serine (or cysteine) proteinase inhibitor, clade B (ovalbumin),...)
  See SERPINB7-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 71 2     PPKN2 5
Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 71 2     Mesangium Predominant Gene, Megsin2
TP552 3     Serpin B72
MEGSIN2 5     Megsin3

External Ids:    HGNC: 139021   Entrez Gene: 87102   Ensembl: ENSG000001663967   OMIM: 6033575   UniProtKB: O756353   

Export aliases for SERPINB7 gene to outside databases

Previous GC identifers: GC18P061281 GC18P059569 GC18P059571 GC18P058121


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SERPINB7 Gene:
SERPINB7 (serpin peptidase inhibitor, clade B (ovalbumin), member 7) is a protein-coding gene. Diseases associated with SERPINB7 include palmoplantar keratoderma, nagashima type, and familial encephalopathy with neuroserpin inclusion bodies. GO annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINE2.

UniProtKB/Swiss-Prot: SPB7_HUMAN, O75635
Function: Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of
megakaryocytes via its action as a serpin

Gene Wiki entry for SERPINB7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the SERPINB7 gene promoter:
         c-Fos   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERPINB7 promoter sequence
   Search Chromatin IP Primers for SERPINB7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SERPINB7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.33   Ensembl cytogenetic band:  18q21.33   HGNC cytogenetic band: 18q21.33

SERPINB7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINB7 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P061394:  view genomic region     (about GC identifiers)

Start:
61,420,169 bp from pter      End:
61,472,604 bp from pter
Size:
52,436 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SPB7_HUMAN, O75635 (See protein sequence)
Recommended Name: Serpin B7  
Size: 380 amino acids; 42905 Da
Secondary accessions: B4DUW8 F5GZC0 Q1ED45 Q3KPG4
Alternative splicing: 2 isoforms:  O75635-1   O75635-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for SERPINB7: NX_O75635

Explore proteomics data for SERPINB7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See SERPINB7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001035237.1  NP_001248759.1  NP_001248760.1  NP_003775.1  

    ENSEMBL proteins: 
     ENSP00000397301   ENSP00000381101   ENSP00000402362   ENSP00000393947   ENSP00000337212  
     ENSP00000444572   ENSP00000444861  

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    Cloud-Clone Corp. Proteins for SERPINB7

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SERPIN: Serine (or cysteine) peptidase inhibitors

    3 InterPro protein domains:
     IPR023795 Serpin_CS
     IPR000215 Serpin_fam
     IPR023796 Serpin_dom

    Graphical View of Domain Structure for InterPro Entry O75635

    ProtoNet protein and cluster: O75635

    2 Blocks protein domains:
    IPB000215 Serpin
    IPB000240 Maspin signature


    UniProtKB/Swiss-Prot: SPB7_HUMAN, O75635
    Similarity: Belongs to the serpin family. Ov-serpin subfamily


    Find genes that share domains with SERPINB7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPB7_HUMAN, O75635
    Function: Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of
    megakaryocytes via its action as a serpin

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IBA--
         
    Find genes that share ontologies with SERPINB7           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SERPINB7
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    4 qRT-PCR Assays for microRNAs that regulate SERPINB7:
    hsa-miR-548am hsa-miR-493* hsa-miR-548x hsa-miR-2278
    SwitchGear 3'UTR luciferase reporter plasmidSERPINB7 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPB7_HUMAN, O75635: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    endoplasmic reticulum2
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with SERPINB7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SERPINB7
    Interactions:

        Search GeneGlobe Interaction Network for SERPINB7

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010951negative regulation of endopeptidase activity IBA--
    GO:0030162regulation of proteolysis IBA--
    GO:0032914positive regulation of transforming growth factor beta1 production IEA--
    GO:0032967positive regulation of collagen biosynthetic process IEA--
    GO:0072126positive regulation of glomerular mesangial cell proliferation IEA--

    Find genes that share ontologies with SERPINB7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SERPINB7 (SPB7)

    1 Novoseek inferred chemical compound relationship for SERPINB7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    serine 58.4 18 14586725 (1), 18645605 (1), 11527413 (1), 9710452 (1) (see all 14)



    Find genes that share compounds with SERPINB7           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for SERPINB7 gene (4 alternative transcripts): 
    NM_001040147.2  NM_001261830.1  NM_001261831.1  NM_003784.3  

    Unigene Cluster for SERPINB7:

    Serpin peptidase inhibitor, clade B (ovalbumin), member 7
    Hs.138202  [show with all ESTs]
    Unigene Representative Sequence: BX641156
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000425392 ENST00000398019(uc002ljm.3 uc010xet.2 uc010dqg.3)
    ENST00000447428 ENST00000431370 ENST00000336429(uc002ljl.3) ENST00000540675
    ENST00000546027
    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate SERPINB7:
    hsa-miR-548am hsa-miR-493* hsa-miR-548x hsa-miR-2278
    SwitchGear 3'UTR luciferase reporter plasmidSERPINB7 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat SERPINB7

    Additional mRNA sequence: 

    AF027866.1 AK290673.1 AK290876.1 AK300828.1 BC069417.1 BC069442.1 BC069547.1 BC106743.2 
    BC106744.2 BX641156.1 D88575.1 

    5 DOTS entries:

    DT.102820873  DT.121102852  DT.40296454  DT.101975076  DT.91803422 

    Selected AceView cDNA sequences (see all 30):

    AI123041 BC069547 AI742488 BG319597 BI335844 BC069417 BP364497 CB305524 
    BP371954 AA374189 BP374157 D88575 AU100197 AI608986 BC069442 BI871335 
    BX284040 BX641156 BG682538 BF435195 CA314431 BG185954 AF027866 CD702645 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SERPINB7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCGTCTGG
    SERPINB7 Expression
    About this image


    SERPINB7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Eye (Sensory Organs)    fully expand to see all 2 entries
             Limbal epithelial stem cells (family)
     
     Fibroblasts
             Detroit 551
     
     Epidermis (Integumentary System)
             Detroit 551
     
     Tonsil (Hematopoietic System)
    SERPINB7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SERPINB7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.138202

    UniProtKB/Swiss-Prot: SPB7_HUMAN, O75635
    Tissue specificity: Predominantly expressed in mesangial cells

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for SERPINB7 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Serpinb71 , 5 serine (or cysteine) peptidase inhibitor, clade B, more1, 5 80.18(n)1
    73.95(a)1
      1 (50.34 cM)5
    1168721  NM_027548.31  NP_081824.11 
     1073996555 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    27(a)
    many ↔ many
    GL343247.1(1696198-1710891)
    fruit fly
    (Drosophila melanogaster)
    Insecta Spn53 serpin 28(a)   88E3   --


    ENSEMBL Gene Tree for SERPINB7 (if available)
    TreeFam Gene Tree for SERPINB7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SERPINB7 gene
    SERPINE22  SERPINB12  SERPINI12  SERPINB52  SERPINB122  SERPINB62  SERPINI22  SERPINB22  
    SERPINC12  SERPINB102  SERPINB92  SERPINB32  SERPINE12  SERPINB112  SERPINE32  SERPINB42  
    SERPINB82  SERPINB132  
    Selected SIMAP similar genes for SERPINB7 using alignment to 3 protein entries:     SPB7_HUMAN (see all proteins) (see all similar genes):
    DKFZp686D06190    SCCA1    SERPINB11    SERPINB3    SERPINB13    SERPINB4
    SCCA2    SERPINB1    SERPINB10    SERPINB12    SERPINC1    SERPINB6
    SERPINB9    SERPINI1    SERPINI2    SERPINA3    SERPINA5    SERPINB8

    Find genes that share paralogs with SERPINB7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SERPINB7 (see all 1356)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1457440141,2
    --61418402(+) ACCATC/TCCACA 1 -- us2k10--------
    rs1847983401,2
    --61418458(+) CCATCA/GCCTGC 1 -- us2k10--------
    rs768182101,2
    C,F--61418572(+) GGAAGT/CTTCCC 1 -- us2k11Minor allele frequency- C:0.08WA 118
    rs99481251,2
    C,F,A,H--61418658(+) TTTCCA/TAAACT 1 -- us2k14Minor allele frequency- T:0.00NS EA 418
    rs1900126461,2
    --61418746(+) CTCACA/GAAGCC 1 -- us2k10--------
    rs170716921,2
    C,F,H--61418760(+) ACCATA/GTTCAA 1 -- us2k19Minor allele frequency- G:0.02NA NS EA WA 792
    rs1808529841,2
    --61418778(+) GTTAAA/GATGGC 1 -- us2k10--------
    rs177079641,2
    C,F,H--61418880(+) AGGAAC/TTGTTA 1 -- us2k113Minor allele frequency- T:0.02NA NS EA 1484
    rs1495785441,2
    --61419018(+) TAAAAC/TAGCAT 1 -- us2k10--------
    rs771943001,2
    C,F--61419078(+) GTGACG/ATAAGT 1 -- us2k11Minor allele frequency- A:0.01NA 120

    HapMap Linkage Disequilibrium report for SERPINB7 (61420169 - 61472604 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SERPINB7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1109412CNV Insertion17803354
    esv21739CNV Gain19812545
    nsv833672CNV Gain17160897

    Human Gene Mutation Database (HGMD): SERPINB7
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing SERPINB7
    DNA2.0 Custom Variant and Variant Library Synthesis for SERPINB7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603357   
    OMIM disorders: 615598  
    4 diseases for SERPINB7:    
    About MalaCards
    palmoplantar keratoderma, nagashima type    familial encephalopathy with neuroserpin inclusion bodies    iga glomerulonephritis    palmoplantar keratosis

    1 disease from the University of Copenhagen DISEASES database for SERPINB7:
    IgA glomerulonephritis

    Find genes that share disorders with SERPINB7           About GenesLikeMe

    10 Novoseek inferred disease relationships for SERPINB7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nephropathy iga 80.5 17 10977777 (3), 11527413 (2), 9710452 (2), 16796905 (2) (see all 9)
    diabetic nephropathies 61.6 11 16037283 (4), 17595191 (1), 18363646 (1), 10589701 (1) (see all 6)
    nephrotic syndrome minimal change 60.5 2 11527413 (1), 10589701 (1)
    proteinuria 52.7 1 17595191 (1)
    nephritis 50.2 2 11473647 (2)
    glomerulosclerosis 49.5 3 17595191 (1), 11473647 (1)
    nephropathy membranous 48 2 11527413 (1), 10589701 (1)
    renal disease 47.7 15 17595191 (4), 18645605 (2), 18471408 (2), 15213261 (1) (see all 6)
    renal failure chronic 29.7 2 17595191 (1), 10589701 (1)
    tumors 0 2 12397041 (1)

    Genetic Association Database (GAD): SERPINB7
    Human Genome Epidemiology (HuGE) Navigator: SERPINB7 (8 documents)

    Export disorders for SERPINB7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for SERPINB7 gene, integrated from 10 sources (see all 47):
    (articles sorted by number of sources associating them with SERPINB7)
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    1. The influence of two megsin polymorphisms on the progression of IgA nephropathy. (PubMed id 18498720)1, 4, 9 MaixnerovA! D....Tesar V. (Folia Biol. (Praha) 2008)
    2. A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy. (PubMed id 9710452)1, 2, 9 Miyata T.... Kurokawa K. (J. Clin. Invest. 1998)
    3. [Correlation between traditional Chinese medicine syndromes in primary immunoglobulin A nephropathy and A267G in 5'-untranslated region within exonal of megsin gene]. (PubMed id 18471408)1, 4, 9 Zhong Y.F....Wang Z.H. (Zhong Xi Yi Jie He Xue Bao 2008)
    4. [Association of single nucleotide polymorphism of megsin gene with IgA nephropathy]. (PubMed id 16796905)1, 4, 9 Wang Z.H....Han B. (Zhonghua Yi Xue Za Zhi 2006)
    5. Megsin 2093T-2180C haplotype at the 3' untranslated region is associated with poor renal survival in Korean IgA nephropathy patients. (PubMed id 18793525)1, 4, 9 Lim C.S....Kim S. (Clin. Nephrol. 2008)
    6. Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy. (PubMed id 16431886)1, 4, 9 Xia Y....Wang Y. (Nephrol. Dial. Transplant. 2006)
    7. Update of the human and mouse SERPIN gene superfamily. (PubMed id 24172014)1, 3 Heit C....Vasiliou V. (Hum. Genomics 2013)
    8. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    9. A family-based association study of megsin A23167G polymorphism with susceptibility and progression of IgA nephropathy in a Chinese population. (PubMed id 16550745)1, 4 Xia Y.F....Li J. (Clin. Nephrol. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8710 HGNC: 13902 AceView: SERPINB7 Ensembl:ENSG00000166396 euGenes: HUgn8710
    ECgene: SERPINB7 H-InvDB: SERPINB7

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for SERPINB7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for SERPINB7 gene:
    Search GeneIP for patents involving SERPINB7

    GeneCards and IP:
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