Aliases for SERPINB3 Gene
External Ids for SERPINB3 Gene
Previous HGNC Symbols for SERPINB3 Gene
Previous GeneCards Identifiers for SERPINB3 Gene
GeneCards Summary for SERPINB3 Gene
SERPINB3 (Serpin Family B Member 3) is a Protein Coding gene. Diseases associated with SERPINB3 include Anal Carcinoma In Situ and Anus Cancer. Among its related pathways are Amoebiasis. GO annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB4.
UniProtKB/Swiss-Prot for SERPINB3 Gene
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).