Aliases for SERPINB13 Gene
External Ids for SERPINB13 Gene
Previous HGNC Symbols for SERPINB13 Gene
Previous GeneCards Identifiers for SERPINB13 Gene
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein inhibits the activity of cathepsin K and is itself transcriptionally repressed by RUNX1. This gene is downregulated in many types of cancer. [provided by RefSeq, Jan 2017]
GeneCards Summary for SERPINB13 Gene
SERPINB13 (Serpin Family B Member 13) is a Protein Coding gene. Diseases associated with SERPINB13 include Squamous Cell Carcinoma, Head And Neck and Psoriasis. Among its related pathways are Amoebiasis. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINB3.
UniProtKB/Swiss-Prot for SERPINB13 Gene
May play a role in the proliferation or differentiation of keratinocytes.