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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERPINB13 Gene

protein-coding   GIFtS: 53
GCID: GC18P061227

serpin peptidase inhibitor, clade B (ovalbumin), member...

(Previous names: serine (or cysteine) proteinase inhibitor, clade B (ovalbumin),...)
(Previous symbol: PI13)
 Explore 9 diseases affiliated with
SERPINB13 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SERPINB13    

Aliases
for SERPINB13 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 131 2     HURPIN2 5
PI131 2 3 5     Hurpin3
HUR71 2     HSHUR7SEQ2
Headpin3     Protease Inhibitor 13 (Hurpin, Headpin)2
Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 131 2     Serpin B132
HaCaT UV-Repressible Serpin2 3     UV-B Repressed Sequence, HUR 72
Peptidase Inhibitor 132 3     Headpin3
Proteinase Inhibitor 132 3     Hurpin3
PI-132 3     

External Ids:    HGNC: 89441   Entrez Gene: 52752   Ensembl: ENSG000001976417   OMIM: 6044455   UniProtKB: Q9UIV83   

Export aliases for SERPINB13 gene to outside databases

Previous GC identifers: GC18P061093 GC18P059403 GC18P059296 GC18P059405 GC18P057954


Summaries
for SERPINB13 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: SPB13_HUMAN, Q9UIV8
Function: May play a role in the proliferation or differentiation of keratinocytes

Gene Wiki entry for SERPINB13


Genomic Views
for SERPINB13 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NC_018929.1  NT_025028.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERPINB13 gene promoter:
         TBP   AML1a   Ik-3   Gfi-1   c-Rel   GCNF-1   TFIID   FOXO1a   GCNF-2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SERPINB13 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERPINB13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPINB13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.33   Ensembl cytogenetic band:  18q21.33   HGNC cytogenetic band: 18q21.33

SERPINB13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINB13 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P061227:  view genomic region     (about GC identifiers)

Start:
 61,254,223 bp from pter      End:
 61,271,873 bp from pter
Size:
 17,651 bases      Orientation:
 plus strand

Proteins
for SERPINB13 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SPB13_HUMAN, Q9UIV8 (See protein sequence)
Recommended Name: Serpin B13  
Size: 391 amino acids; 44276 Da
Subcellular location: Cytoplasm
Secondary accessions: A8K2Q8 Q3MII2 Q9HCX1 Q9UBW1 Q9UKG0
Alternative splicing: 2 isoforms:  Q9UIV8-1   Q9UIV8-2   

Explore the universe of human proteins at neXtProt for SERPINB13: NX_Q9UIV8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UIV8

    • SERPINB13 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036529.1  
    ENSEMBL proteins: 
     ENSP00000388300   ENSP00000341584   ENSP00000394592   ENSP00000391156   ENSP00000269489  

    Human Recombinant Protein Products: 
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    Novus Biologicals SERPINB13 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SERPINB13

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IBA--
    GO:0005737cytoplasm IEA--


    SERPINB13 for ontologies           About GeneDecksing



    SERPINB13 Antibody Products: 
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    Uscn Antibodies for SERPINB13
    ThermoFisher Antibodies for SERPINB13

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    Uscn ELISAs and CLIAs for SERPINB13

    Protein Domains /
    Families
    for SERPINB13 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SERPINB13 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR023795 Protease_inhib_I4_serpin_CS
     IPR023796 Serpin_dom
     IPR000215 Serpin_fam

    Graphical View of Domain Structure for InterPro Entry Q9UIV8

    ProtoNet protein and cluster: Q9UIV8

    1 Blocks protein family: IPB000215 Serpin

    UniProtKB/Swiss-Prot: SPB13_HUMAN, Q9UIV8
    Similarity: Belongs to the serpin family. Ov-serpin subfamily


    Function
    for SERPINB13 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SPB13_HUMAN, Q9UIV8
    Function: May play a role in the proliferation or differentiation of keratinocytes

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: SERPINB13 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: SERPINB13
    OriGene siRNA: SERPINB13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERPINB13

    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for SERPINB13

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity NAS10512713


    SERPINB13 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for SERPINB13:
     Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for SERPINB13 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Amoebiasis
    		Amoebiasis1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways



    1         Kegg Pathway  (Kegg details for SERPINB13):
        Amoebiasis


    SERPINB13 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SERPINB13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for SERPINB13 (Q9UIV83 ENSP000003415844) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTSBP078583, ENSP000003420704I2D: score=1 STRING: ENSP00000342070
    PRTN3P241583, ENSP000002343474I2D: score=1 STRING: ENSP00000234347
    CTSGP083113, ENSP000002163364I2D: score=1 STRING: ENSP00000216336
    CTSKP432353, ENSP000002716514I2D: score=1 STRING: ENSP00000271651
    CTSL1P077113, ENSP000003453444I2D: score=1 STRING: ENSP00000345344
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009411response to UV TAS9297979
    GO:0010951negative regulation of endopeptidase activity IBA--
    GO:0030162regulation of proteolysis NAS10512713


    SERPINB13 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SERPINB13 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SERPINB13 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERPINB13
    3 Novoseek chemical compound relationships for SERPINB13 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    scca1 90.6 2 14647462 (2)
    serine 61.3 20 10512713 (3), 11313015 (2), 12504904 (2), 10527881 (1) (see all 10)
    cysteine 38.2 5 12504904 (2), 12809493 (1), 17697143 (1)

    Search CenterWatch for drugs/clinical trials and news about SERPINB13 / SPB13 

    Transcripts
    for SERPINB13 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SERPINB13 gene: 
    NM_012397.3  

    Unigene Cluster for SERPINB13:

    Serpin peptidase inhibitor, clade B (ovalbumin), member 13
    Hs.241407  [show with all ESTs]
    Unigene Representative Sequence: NM_012397
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000431153 ENST00000344731(uc002ljc.3 uc002ljd.3 uc010xep.2 uc010xeq.2 uc010xer.2)
    ENST00000479842 ENST00000438844 ENST00000415733 ENST00000269489

    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate SERPINB13:
    hsa-miR-4307 hsa-miR-130b*
    SwitchGear 3'UTR luciferase reporter plasmid: SERPINB13 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERPINB13 (see all 7)
    OriGene shRNA RFP: SERPINB13
    OriGene siRNA: SERPINB13
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERPINB13
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPINB13
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERPINB13

    Additional cDNA sequence: 

    AF169949.1 AJ001696.2 AJ001697.2 AJ001698.1 AK290323.1 AK296797.1 AK298049.1 AK303867.1 
    AK303979.1 AK313486.1 AL050177.1 BC101821.1 BC143402.1 

    5 DOTS entries:

    DT.86844860  DT.121103760  DT.95346969  DT.40117455  DT.97766708 

    20 AceView cDNA sequences:

    X98307 AL050177 BG698108 BU679351 CA433041 AL703073 AJ001698 BP352276 
    NM_012397 BM988172 AJ001697 BU674040 AL603092 AL603394 BU686890 AF169949 
    AJ001696 BM975846 AW873025 BQ353844 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for SERPINB13    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                                            -     -                       -                     
    SP2:                                            -     -                                             
    SP3:        -     -     -                       -     -                                             
    SP4:                                                  -     -     -     -                           
    SP5:                                                                                                


    ECgene alternative splicing isoforms for SERPINB13

    Expression
    for SERPINB13 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERPINB13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SERPINB13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERPINB13

    SOURCE GeneReport for Unigene cluster: Hs.241407

    UniProtKB/Swiss-Prot: SPB13_HUMAN, Q9UIV8
    Tissue specificity: Skin specific

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    In Situ
    Assay Products:     
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    Orthologs
    for SERPINB13 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for SERPINB13 gene from 2/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 45(a)
    44(a)
    		 many ↔ many
    many ↔ many
    		 GL343311.1(570280-578337)
    GL343311.1(623565-636049)
    zebrafish
    (Danio rerio)    		 Actinopterygii serpinb1l16
    zgc:1737296
    (see all 5)    		 zgc:173729
    (see all 5)    		 43(a)
    40(a)
    (see all 5)    		 many ↔ many
    many ↔ many
    (see all 5)    		 16(54874440-54879870)
    16(54858268-54864487)


    ENSEMBL Gene Tree for SERPINB13 (if available)
    TreeFam Gene Tree for SERPINB13 (if available) 

    Paralogs
    for SERPINB13 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERPINB13 gene
    SERPINB72  SERPINB12  SERPINI12  SERPINB52  SERPINB122  SERPINI22  SERPINB22  SERPINB102  
    SERPINB32  SERPINB42  SERPINE22  SERPINB62  SERPINC12  SERPINB92  SERPINE12  SERPINE32  
    SERPINB82  
    18/36 SIMAP similar genes for SERPINB13 using alignment to 5 protein entries:     SPB13_HUMAN (see all proteins) (see all similar genes):
    HUR 7    SCCA1    SERPINB3    SCCA2    PLANH2    SERPINB4
    SERPINB10    SERPINB11    AT3    DKFZp686O07189    SERPINB1    SERPINB7
    SERPINB12    DKFZp686D06190    SERPINB6    SERPINB9    SERPINB2    SERPINB8

    SERPINB13 for paralogs           About GeneDecksing



    Genomic Variants
    for SERPINB13 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/288 NCBI SNPs in SERPINB13 are shown (see all 288)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 18 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1500650271,2
    		--61252639(+) AACATC/TGGCAG 1 -- us2k10--------
    rs739617621,2
    		C,--61252662(+) GATTAC/TATGCT 1 -- us2k12Minor allele frequency- T:0.16WA 120
    rs1453974381,2
    		--61252663(+) ATTACA/GTGCTT 1 -- us2k10--------
    rs1924446401,2
    		--61252664(+) TTACAA/TGCTTG 1 -- us2k10--------
    rs1423673041,2
    		--61252695(+) TCAGTA/GTCAGT 1 -- us2k10--------
    rs18092031,2
    		C,F,A,H,--61252740(-) CTGTTC/GCATAG 1 -- us2k115Minor allele frequency- G:0.49NS EA NA WA 928
    rs1842299811,2
    		--61252843(+) TCAACA/GTATAT 1 -- us2k10--------
    rs1882817451,2
    		--61252927(+) GAGGTC/TGGGAA 1 -- us2k10--------
    rs1463539611,2
    		--61252989(+) TGGAGA/GTGCTT 1 -- us2k10--------
    rs1391919641,2
    		--61253025(+) GTGTGA/GGTGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SERPINB13 (61254223 - 61271873 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SERPINB13: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERPINB13
    DNA2.0 Custom Variant and Variant Library Synthesis for SERPINB13

    Disorders / Diseases
    for SERPINB13 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SERPINB13 for disorders           About GeneDecksing

    OMIM gene information: 604445    OMIM disorders: --

    9 diseases for SERPINB13:    About MalaCards
    pyoderma gangrenosum    pyoderma    folliculitis    skin disease
    squamous cell carcinoma    psoriasis    nephropathy    lung cancer
    carcinoma

    9 Novoseek disease relationships for SERPINB13 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hnscc 65.6 12 19569240 (5), 14698630 (1), 12874078 (1)
    carcinoma squamous cell 57.6 6 16357159 (2), 11004515 (1), 19569240 (1), 14647462 (1)
    psoriasis 44.3 3 11313015 (1), 15885077 (1), 10512713 (1)
    skin diseases 42.9 3 17697143 (1), 15885077 (1), 10512713 (1)
    neck cancer 37.4 2 11004515 (2)
    skin lesion 33.5 1 10512713 (1)
    carcinoma 1.98 2 11313015 (1), 15885077 (1)
    tumors 1.35 12 16357159 (2), 12874078 (2), 19569240 (2), 14698630 (1)
    cancer 0 1 16357159 (1)

    Human Genome Epidemiology (HuGE) Navigator: SERPINB13 (1 document)

    Export disorders for SERPINB13 gene to outside databases

    Publications
    for SERPINB13 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERPINB13 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with SERPINB13)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of hurpin (Protease Inhibitor 13): a new skin specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family. (PubMed id 10512713)1, 2, 3, 9 Abts H.F....Ruzicka T. (1999)
    2. Sequence, organization, chromosomal localization and alternative splicing of the human serine protease inhibitor gene hurpin (PI13), which is up-regulated in psoriasis. (PubMed id 11313015)1, 2, 9 Abts H.F.... Ruzicka T. (2001)
    3. Identification and cDNA cloning of headpin, a novel differentially expressed serpin that maps to chromosome 18q. (PubMed id 10527881)1, 2, 9 Spring P.... Clayman G. (1999)
    4. Genomic cloning, mapping, structure and promoter analysis of HEADPIN, a serpin which is down-regulated in head and neck cancer cells. (PubMed id 11004515)1, 2, 9 Nakashima T....Clayman G.L. (2000)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Analysis of UV-B modulated gene expression in human keratinocytes by mRNA differential display PCR (DD-PCR). (PubMed id 9297979)1, 3 Abts H.F.... Ruzicka T. (1997)
    7. Expression of hurpin, a serine proteinase inhibitor, in normal and pathological skin: overexpression and redistribution in psoriasis and cutaneous carcinomas. (PubMed id 15885077)1, 9 Moussali H....Walz M. (2005)
    8. Inhibition of the cysteine proteinases cathepsins K and L by the serpin headpin (SERPINB13): a kinetic analysis. (PubMed id 12504904)1, 9 Jayakumar A....Clayman G.L. (2003)
    9. Downregulation of SERPINB13 expression in head and ne ck squamous cell carcinomas associates with poor clinical outcome. (PubMed id 19569240)1, 9 de Koning P.J....Kummer J.A. (2009)
    10. Headpin: a serpin with endogenous and exogenous suppression of angiogenesis. (PubMed id 16357159)1, 9 Shellenberger T.D....Clayman G.L. (2005)

    External Searches for SERPINB13 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing SERPINB13 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5275 HGNC: 8944 AceView: SERPINB13 Ensembl:ENSG00000197641 euGenes: HUgn5275
    ECgene: SERPINB13 Kegg: 5275 H-InvDB: SERPINB13

    Other Databases showing SERPINB13 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SERPINB13 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERPINB13 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for SERPINB13 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SERPINB13 gene:
    Search GeneIP for patents involving SERPINB13

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