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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERPINB12 Gene

protein-coding   GIFtS: 49
GCID: GC18P061196

Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member...

(Previous names: serine (or cysteine) proteinase inhibitor, clade B (ovalbumin),...)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 121 2
Serine (Or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 121 2
YUKOPIN2
Serpin B122

External Ids:    HGNC: 142201   Entrez Gene: 897772   Ensembl: ENSG000001666347   UniProtKB: Q96P633   

Export aliases for SERPINB12 gene to outside databases

Previous GC identifers: GC18P061062 GC18P059372 GC18P059374 GC18P057923


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SERPINB12 Gene: 
SERPINB12 (serpin peptidase inhibitor, clade B (ovalbumin), member 12) is a protein-coding gene. Diseases associated with SERPINB12 include hepatocellular carcinoma. GO annotations related to this gene include serine-type endopeptidase inhibitor activity and enzyme binding. An important paralog of this gene is SERPINB7.

UniProtKB/Swiss-Prot: SPB12_HUMAN, Q96P63
Function: Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen
activator




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000018.9  NT_025028.14  NC_018929.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERPINB12 gene promoter:
         Brachyury   STAT5A   C/EBPalpha   CHOP-10   PPAR-gamma1   CBF-B   CBF-A   PPAR-gamma2   Pax-4a   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERPINB12 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERPINB12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPINB12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  18q21.33   HGNC cytogenetic band: 18q21.33

SERPINB12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINB12 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P061196:  view genomic region     (about GC identifiers)

Start:
61,223,393 bp from pter      End:
61,234,244 bp from pter
Size:
10,852 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SPB12_HUMAN, Q96P63 (See protein sequence)
Recommended Name: Serpin B12  
Size: 405 amino acids; 46276 Da
Subcellular location: Cytoplasm (By similarity)

Explore the universe of human proteins at neXtProt for SERPINB12: NX_Q96P63

Explore proteomics data for SERPINB12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96P63

  • SERPINB12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SERPINB12 Protein Expression
    REFSEQ proteins: NP_536722.1  
    ENSEMBL proteins: 
     ENSP00000269491   ENSP00000372218  

    Human Recombinant Protein Products for SERPINB12: 
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    Sino Biological Recombinant Protein for SERPINB12
    Sino Biological Cell Lysate for SERPINB12 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for SERPINB12 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005737cytoplasm NAS11604408

    SERPINB12 for ontologies           About GeneDecksing



    SERPINB12 Antibody Products: 
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    Assay Products for SERPINB12: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for SERPINB12 
    Cloud-Clone Corp. CLIAs for SERPINB12


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SERPIN: Serine (or cysteine) peptidase inhibitors

    3 InterPro protein domains:
     IPR023795 Protease_inhib_I4_serpin_CS
     IPR023796 Serpin_dom
     IPR000215 Serpin_fam

    Graphical View of Domain Structure for InterPro Entry Q96P63

    ProtoNet protein and cluster: Q96P63

    1 Blocks protein domain: IPB000215 Serpin

    UniProtKB/Swiss-Prot: SPB12_HUMAN, Q96P63
    Similarity: Belongs to the serpin family. Ov-serpin subfamily


    SERPINB12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPB12_HUMAN, Q96P63
    Function: Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen
    activator

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IMP11604408
    GO:0019899enzyme binding NAS11604408
         
    SERPINB12 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SERPINB12:
     Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SERPINB12 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SERPINB12

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SERPINB12 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SERPINB12 

    miRNA
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    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for SERPINB12
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: SERPINB12 (NM_080474)
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPINB12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SERPINB12

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/22 Interacting proteins for SERPINB12 (Q96P633 ENSP000002694914) via UniProtKB, MINT, STRING, and/or I2D (see all 22)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SERPINF2P086973, ENSP000003218534I2D: score=1 STRING: ENSP00000321853
    UCHL5Q9Y5K53, ENSP000003564254I2D: score=1 STRING: ENSP00000356425
    AMBRA1Q9C0C73I2D: score=1 
    ATG12O948173I2D: score=1 
    ATG7O953523I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0010951negative regulation of endopeptidase activity IBA--
    GO:0030162regulation of proteolysis IBA--
    GO:0042177negative regulation of protein catabolic process NAS11604408

    SERPINB12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERPINB12 (SPB12)

    Search CenterWatch for drugs/clinical trials and news about SERPINB12 / SPB12

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SERPINB12 gene: 
    NM_080474.1  

    Unigene Cluster for SERPINB12:

    Serpin peptidase inhibitor, clade B (ovalbumin), member 12
    Hs.348541  [show with all ESTs]
    Unigene Representative Sequence: AK309754
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000269491(uc010xen.2) ENST00000382768(uc010xeo.2)
    miRNA
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SERPINB12
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERPINB12
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    GenScript: all cDNA clones in your preferred vector: SERPINB12 (NM_080474)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERPINB12
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERPINB12
    Sirion Biotech Customized lentivirus for stable overexpression of SERPINB12 
                         Customized lentivirus expression plasmids for stable overexpression of SERPINB12 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for SERPINB12
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SERPINB12
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPINB12
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERPINB12

    Additional mRNA sequence: 

    AF411191.1 AK309754.1 BC103884.1 BC103885.1 

    2 DOTS entries:

    DT.40114024  DT.95152559 

    8 AceView cDNA sequences:

    AF411191 NM_080474 W74427 BG677045 AA242834 BX090362 W79181 AA242969 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERPINB12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCATTACGG
    SERPINB12 Expression
    About this image


    See SERPINB12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERPINB12

    SOURCE GeneReport for Unigene cluster: Hs.348541

    UniProtKB/Swiss-Prot: SPB12_HUMAN, Q96P63
    Tissue specificity: Expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver,
    pancreas, testis, ovary, and intestine

        SABiosciences Custom PCR Arrays for SERPINB12
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERPINB12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SERPINB12 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Serpinb121 , 5 serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), more1, 5 78.68(n)1
    72.84(a)1
      1 (50.34 cM)5
    718691  NM_001199213.11  NP_001186142.11 
     1069344495 
    chicken
    (Gallus gallus)
    Aves SERPINB121 serpin peptidase inhibitor, clade B (ovalbumin), member more 57.12(n)
    46.91(a)
      420899  XM_418985.2  XP_418985.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    44(a)
    44(a)
    (see all 3)
    possible ortholog
    many ↔ many
    (see all 3)
    GL343311.1(703856-715609)
    GL343311.1(595295-637065)
    zebrafish
    (Danio rerio)
    Actinopterygii serpinb1l16
    serpinb16
    (see all 7)
    serpin peptidase inhibitor, clade B (ovalbumin), m...
    serpin peptidase inhibitor, clade B (ovalbumin), m...
    (see all 7)
    46(a)
    42(a)
    (see all 7)
    possible ortholog
    many ↔ many
    (see all 7)
    16(54874440-54879870)
    20(26910467-26916434)


    ENSEMBL Gene Tree for SERPINB12 (if available)
    TreeFam Gene Tree for SERPINB12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERPINB12 gene
    SERPINB72  SERPINB12  SERPINI12  SERPINB52  SERPINI22  SERPINB22  SERPINB102  SERPINB32  
    SERPINB42  SERPINE22  SERPINB62  SERPINC12  SERPINB92  SERPINE12  SERPINB112  SERPINE32  
    SERPINB132  SERPINB82  
    18/38 SIMAP similar genes for SERPINB12 using alignment to 3 protein entries:     SPB12_HUMAN (see all proteins) (see all similar genes):
    SCCA1    AT3    PLANH2    DKFZp686O07189    SERPINB11    DKFZp686D06190
    SERPINB10    SERPINB3    SERPINB8    SERPINB1    SCCA2    SERPINB4
    SERPINB9    SERPINB13    SERPINB2    SERPINB6    SERPINB7    SERPINB5

    SERPINB12 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/373 SNPs in SERPINB12 are shown (see all 373)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs782624691,2
    C--61221425(+) CAGTTG/AAGGGG 1 -- us2k13Minor allele frequency- A:0.15CSA NA EA 242
    rs1507708821,2
    --61221466(+) ATTACG/TTAGTT 1 -- us2k10--------
    rs1176439431,2
    C,F--61221476(+) TTGGGG/ACCAAA 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs1392225571,2
    C--61221610(+) TTTTAA/GAAAGT 1 -- us2k10--------
    rs129684301,2
    C,F--61221627(+) ATGTTA/TTCTTT 1 -- us2k17Minor allele frequency- T:0.29NA WA EA 366
    rs745844821,2
    C--61221655(+) GGCTAA/TGAAAA 1 -- us2k10--------
    rs797260401,2
    C--61221656(+) GCTAAC/GAAAAT 1 -- us2k10--------
    rs775520351,2
    C--61221657(+) CTAAGA/TAAATC 1 -- us2k10--------
    rs1495392161,2
    C--61221739(+) TGGTGC/TGCTGT 1 -- us2k10--------
    rs1899154651,2
    --61221768(+) AAATAA/GGAGGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for SERPINB12 (61223393 - 61234244 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for SERPINB12: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing SERPINB12
    DNA2.0 Custom Variant and Variant Library Synthesis for SERPINB12

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for SERPINB12:    About MalaCards
    hepatocellular carcinoma    


    SERPINB12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SERPINB12

    Export disorders for SERPINB12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERPINB12 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with SERPINB12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases. (PubMed id 11604408)1, 2 Askew Y.S.... Silverman G.A. (2001)
    2. The interaction between ubiquitin C-terminal hydrolas e 37 and glucose-regulated protein 78 in hepatocellular carcinoma. (PubMed id 21800051)1 Fang Y....Shen X. (2012)
    3. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    4. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    5. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    6. Charting the molecular network of the drug target Bcr-Abl. (PubMed id 19380743)1 Brehme M....Superti-Furga G. (2009)
    7. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    8. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Analysis of vertebrate genomes suggests a new model for clade B serpin evolution. (PubMed id 16305753)9 Kaiserman D. and Bird P.I. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 89777 HGNC: 14220 AceView: SERPINB12 Ensembl:ENSG00000166634 euGenes: HUgn89777
    ECgene: SERPINB12 H-InvDB: SERPINB12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERPINB12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SERPINB12 gene:
    Search GeneIP for patents involving SERPINB12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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