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SERPINA5 Gene

protein-coding GIFtS: 63

GC14P094117

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
(Previous names: serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: PLANH3, PCI)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
PAI-3 ^³
PAI3 ^¹, ², ³
PCI ^², ³, ⁵
PLANH3 ^², ³, ⁵
PROCI ^¹, ², ³

Descriptions
Acrosomal serine protease inhibitor ^³
Plasminogen activator inhibitor 3 ^³
Protein C inhibitor ^³
Serpin A5 ^³
plasminogen activator inhibitor III ^²
plasminogen activator inhibitor-3 ^²
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 ^¹, ²
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 ^²

External Ids
HGNC: 8723¹
Entrez Gene: 5104²
UniProtKB: P05154³
Ensembl: ENSG00000188488⁷

Search outside databases for aliases for SERPINA5 gene

Previous GC identifers: GC14P092555 GC14P088864 GC14P093018 GC14P093021 GC14P093037

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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UniProtKB/Swiss-Prot: IPSP_HUMAN, P05154

Function: Inhibits activated protein C as well as plasminogen activators

Gene Wiki entry for SERPINA5 (Protein_C_inhibitor)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SERPINA5 gene

Entrez Gene cytogenetic band: 14q32.1 Ensembl cytogenetic band: 14q32.13 HGNC cytogenetic band: 14q32.1

SERPINA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P094117: (about GC identifiers)

Start:	94,117,564 bp from pter
End:	94,129,205 bp from pter
Size:	11,642 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: IPSP_HUMAN, P05154 (See protein sequence)

Recommended Name: Plasma serine protease inhibitor precursor

Size: 406 amino acids; 45702 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1LQ8 (3D)

1PAI (3D)

2HI9 (3D)

2OL2 (3D)

2PAI (3D)

3DY0 (3D)

Secondary accessions: Q07616 Q9UG30

REFSEQ proteins: NP_000615.3

ENSEMBL proteins:

ENSP00000333203

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for SERPINA5 (Serpin A5/Protein C Inhibitor)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Protein C inhibitor)
	Human Recombinant Proteins from Abnova (SERPINA5)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	TAS	11120760
GO:0016020	membrane	IDA	7521127
GO:0043234	protein complex	IDA	7521127

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Antibodies for SERPINA5:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for SERPINA5
	R&D Systems Antibodies for SERPINA5 (Serpin A5/Protein C Inhibitor)
	Antibodies from Abcam (Protein C inhibitor), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SERPINA5)
	Novus Biologicals Antibodies for SERPINA5

Assays for SERPINA5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P05154

ProtoNet protein and cluster: P05154

1 Blocks protein family: IPB000215 Serpin

UniProtKB/Swiss-Prot: IPSP_HUMAN, P05154

Similarity: Belongs to the serpin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SERPINA5)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000624

Applied Biosystems Silencer® siRNAs for SERPINA5

Sigma-Aldrich siRNA and siRNA Panels for SERPINA5

Sigma-Aldrich shRNA Panels and shRNA for SERPINA5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000624
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000624
untagged cDNA clone in CMV expression vector: NM_000624

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000624

UniProtKB/Swiss-Prot: IPSP_HUMAN, P05154

Function: Inhibits activated protein C as well as plasminogen activators

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Serpina5):

endocrine/exocrine gland

reproductive system

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002020	protease binding	IPI	15853774
GO:0004867	serine-type endopeptidase inhibitor activity	IDA	7521127
GO:0005515	protein binding	IEA	--
GO:0008201	heparin binding	TAS	11120760
GO:0032190	acrosin binding	IPI	7521127

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for SERPINA5 (Your Favorite Gene powered by Ingenuity)

Coagulation System

GeneDecks SERPINA5 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for SERPINA5

5/23 Interacting proteins for SERPINA5 (ENSP00000333203³ P05154²) via UniProtKB, MINT, and/or STRING (see all 23 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
COPS6	Q7L5N1²	MINT-63402
PROC	ENSP00000234071³	STRING (score=.996)
PLAU	ENSP00000361848³	STRING (score=.99)
KLK3	ENSP00000314151³	STRING (score=.988)
KLKB1	ENSP00000264690³	STRING (score=.967)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007283	spermatogenesis	ISS	--
GO:0007342	fusion of sperm to egg plasma membrane	NAS	9510955
GO:0045861	negative regulation of proteolysis	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SERPINA5
1 Novoseek chemical compound relationship for SERPINA5 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
fibrinogen	37.05	2	8128433 (1), 7571997 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SERPINA5)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000624

Sigma-Aldrich siRNA and siRNA Panels for SERPINA5

Sigma-Aldrich shRNA Panels and shRNA for SERPINA5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000624

REFSEQ mRNAs for SERPINA5 gene:

NM_000624.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000624

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000624
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000624
                                 untagged cDNA clone in CMV expression vector: NM_000624

Additional cDNA sequence:

AK096131.1 AK293192.1 AK298279.1 AK309586.1 AK310869.1 AK313196.1 AL080185.1 BC008915.2

BC014992.1 BX248009.1 BX248760.1 CR605698.1 CR622620.1 J02639.1 L19684.1 S58545.1

U35464.1

24/29 DOTS entries (see all 29 ):

DT.85104682 DT.100831497 DT.95255240 DT.91926531 DT.446447 DT.120779232 DT.92400801 DT.87016075

DT.91944271 DT.92430151 DT.120779169 DT.101978469 DT.120779330 DT.92430155 DT.120779240 DT.120779247

DT.95231261 DT.95255243 DT.100668663 DT.100678995 DT.120779130 DT.120779133 DT.120779181 DT.120779188

24/1378 AceView cDNA sequences (see all 1378 ):

CB163692 BC034554 CR625124 BM821233 BI825717 BM710517 N59384 BQ007994

T29357 BC013189 AA343716 CB154133 BE728135 BU177847 BU727982 AW205285

AI146388 BX448791 BE813691 CR602814 CB162531 AI206127 BU734345 AA345271

highest scoring ESTs for SERPINA5:

AA337036 AA341620 AA576058 AA613884 AA701671 AA876209 AA906782 AA922777 AA922910 AA934730

Unigene Cluster for SERPINA5:

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

Hs.159628 [show with all ESTs]

Unigene Representative Sequence: NM_000624

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for SERPINA5 (see all 10 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3a	·	3b	·	3c	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	^	6a	·	6b	·	6c	·	6d	^	7	^	8a	·	8b	·	8c	^	9	^	10	^	11a	·
SP1:											-		-		-		-		-								-		-		-
SP2:													-		-		-		-
SP3:									-		-		-		-		-		-						-		-		-		-		-		-		-		-
SP4:
SP5:													-		-		-		-

ExUns:	11b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for SERPINA5

1 Ensembl transcript including schematic representation:

ENST00000329597

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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SERPINA5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SERPINA5

¹ / ² / ³

3 probe-sets matching SERPINA5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
37008_r_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M68516	0.20	1.00	0.72	1
209443_at²^{, 3}	U133-A	2	1.00	0.95	--	--	J02639	0.80	0.88	0.84	1
209443_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--

GeneDecks SERPINA5 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.159628
Expression variation in blood from EXPOLDB for SERPINA5
UniProtKB/Swiss-Prot: IPSP_HUMAN, P05154
Tissue specificity: Expressed by the liver and secreted in plasma

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for SERPINA5 gene from 5 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SERPINA5¹	--	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, more	81.32(n) 73.09(a)	480424 XM_537545.2 XP_537545.1
cow (Bos taurus)	SERPINA5¹	--	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, more	79.85(n) 72.14(a)	338050 NM_176646.2 NP_788819.1
rat (Rattus norvegicus)	Serpina5¹	--	serine (or cysteine) peptidase inhibitor, clade A, more	73.93(n) 64.11(a)	65051 NM_022957.2 NP_075246.2
mouse (Mus musculus)	Serpina5^{1, 5}	12⁵	serine (or cysteine) peptidase inhibitor, clade A, more^{1, 5}	73.51(n)¹ 63.61(a)¹	268591¹ NM_172953.2¹ NP_766541.1¹ AH006766⁵ AK077160⁵ (see all 9)
worm (Caenorhabditis elegans)	srp-1³	V(753188-754813)	serine protease inhibitor	29(a)	--

About this table Species with no ortholog for SERPINA5

ENSEMBL Gene Tree for SERPINA5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for SERPINA5 gene

SERPINA1² SERPINA3² SERPINA2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
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10/170 NCBI SNPs in SERPINA5 are shown (see all 170 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 146)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1475938^1,2	A,C,F,H,O	94116769(+)	`CCGGTG/ATCTTG`	1	--	ng5¹		12	EU EA WA NA	1056
	rs2069996^1,2	A,C,F,H,O	94129617(+)	`GTGCCG/AAATGA`	1	--	ng3¹		4	NS EA	252
	rs10144561^1,2	A,C,F,H	94115657(+)	`ATCCAT/CGACAA`	1	--	ng5¹ tfbs³		4	EU EA WA	382
	rs6108^1,2	A,C,F,H	94128384(+)	`GGCTAA/TGCTAT`	1	--	ut3¹		15	NS MN EA NA EU WA	1316
	rs938^1,2	A,C,F,H	94128566(+)	`GATTAA/GCACTG`	1	--	ut3¹ ese³		12	NS EA MN EU WA NA	2382
	rs2069995^1,2	A,C,F,O	94129535(+)	`CAGGGA/GCATCT`	1	--	ng3¹		2	NS	86
	rs6119^1,2	A,C,F,H	94123765(+)	`CAGAGA/GAGGAG`	1	K/E	mis¹ ese³ trp³		18	MN NS NA EU EA WA	1656
	rs11847362^1,2	A,C,F,H	94117150(+)	`CCCCCC/TCTAAT`	1	--	ng5¹		4	EU EA WA	414
	rs2069993^1,2	A,C,F,H	94128940(+)	`AGAAAG/AGCTGG`	1	--	ut3¹ ese³		9	NS EU EA WA NA	642
	rs2069992^1,2	A,C,F,H	94128760(+)	`CAACTG/CTCAGT`	1	--	ut3¹		13	NS EU EA WA NA	1048

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HapMap Linkage Disequilibrium images for SERPINA5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 601841

2 Novoseek disease relationships for SERPINA5 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
venous thrombosis	22.60	2	8418545 (1), 12139754 (1)
tumors	0.00	4	18983517 (2), 2153429 (1)

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Genetic Association Database: SERPINA5
Human Genome Epidemiology Navigator: SERPINA5 (1 document)

(Possibly Related Articles in Doctor's Guide)
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(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/90 PubMed articles for SERPINA5 gene (see all 90 ):

Organization of the gene coding for human protein C inhibitor (plasminogen activator inhibitor-3). Assignment of the gene to chromosome 14. (PubMed id 1714450)^{1, 2, 3, 4} Meijers J.C.M. and Chung D.W. (1991)
Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)^{3, 4} Liu T.... Smith R.D. (2005)
Absence of mutations in the PCI gene in subfertile men. (PubMed id 15377716)^{3, 6} Gianotten J....Meijers J.C. (2004)
Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. (PubMed id 14760718)^{3, 4} Bunkenborg J.... Wisniewski J.R. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Characterization of single-nucleotide polymorphisms in coding regions of human genes. (PubMed id 10391209)^{3, 4} Cargill M....Lander E.S. (1999)
A two-allele polymorphism in protein C inhibitor with varying frequencies in different ethnic populations. (PubMed id 8713781)^{3, 4} Radtke K.P....Griffin J.H. (1996)
Human sperm-egg binding is inhibited by peptides corresponding to core region of an acrosomal serine protease inhibitor. (PubMed id 8471250)^{3, 4} Moore A.... Moore H.D. (1993)
Gene organization of human protein C inhibitor, a member of SERPIN family proteins encoded in five exons. (PubMed id 8148499)^{3, 4} Hayashi T. and Suzuki K. (1993)
Physical mapping of four serpin genes: alpha 1-antitrypsin, alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome I4q32.1. (PubMed id 8381582)^{2, 3} Billingsley G.D....Cox D.W. (1993)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 5104	HGNC: 8723	AceView: SERPINA5andSERPINA3	Ensembl:ENSG00000188488	euGenes: HUgn5104
ECgene: SERPINA5	H-InvDB: SERPINA5

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
SeattleSNPs	http://pga.gs.washington.edu/data/serpina5/

Licensable Technologies for SERPINA5
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for SERPINA5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SERPINA5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SERPINA5		Antibodies for SERPINA5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SERPINA5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (Protein C inhibitor)
	Antibodies (Protein C inhibitor)

Search OriGene for SERPINA5

Search Tocris compounds for SERPINA5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SERPINA5

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SERPINA5 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for SERPINA5

Summaries
for SERPINA5

Genomic Location
for SERPINA5

Proteins
for SERPINA5

Protein Domains/
Families
for SERPINA5

Gene Function
for SERPINA5

Pathways & Interactions
for SERPINA5

Drugs & Compounds
for SERPINA5

Transcripts
for SERPINA5

Expression
for SERPINA5

Orthologs
for SERPINA5

Paralogs
for SERPINA5

SNPs/Variants
for SERPINA5

Disorders & Mutations
for SERPINA5

Medical News
for SERPINA5

Publications
for SERPINA5

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Genome Databases showing SERPINA5

Other Databases showing SERPINA5

Specialized Databases showing SERPINA5

Licensable Technologies
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Services
for SERPINA5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SERPINA5 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor SERPINA5

Summariesfor SERPINA5

Genomic Locationfor SERPINA5

Proteinsfor SERPINA5

Protein Domains/Familiesfor SERPINA5

Gene Functionfor SERPINA5

Pathways & Interactionsfor SERPINA5

Drugs & Compoundsfor SERPINA5

Transcriptsfor SERPINA5

Expression for SERPINA5

Orthologsfor SERPINA5

Paralogsfor SERPINA5

SNPs/Variantsfor SERPINA5

Disorders & Mutationsfor SERPINA5

Medical Newsfor SERPINA5

Publicationsfor SERPINA5

Search for SERPINA5

Genome Databases showing SERPINA5

Other Databases showing SERPINA5

Specialized Databases showing SERPINA5

Licensable Technologiesfor SERPINA5

Servicesfor SERPINA5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SERPINA5

Summaries
for SERPINA5

Genomic Location
for SERPINA5

Proteins
for SERPINA5

Protein Domains/
Families
for SERPINA5

Gene Function
for SERPINA5

Pathways & Interactions
for SERPINA5

Drugs & Compounds
for SERPINA5

Transcripts
for SERPINA5

Expression
for SERPINA5

Orthologs
for SERPINA5

Paralogs
for SERPINA5

SNPs/Variants
for SERPINA5

Disorders & Mutations
for SERPINA5

Medical News
for SERPINA5

Publications
for SERPINA5

Licensable Technologies
for SERPINA5

Services
for SERPINA5