Aliases for SERPINA4 Gene
External Ids for SERPINA4 Gene
Previous HGNC Symbols for SERPINA4 Gene
Previous GeneCards Identifiers for SERPINA4 Gene
GeneCards Summary for SERPINA4 Gene
SERPINA4 (Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase inhibitor activity. An important paralog of this gene is SERPINA10.
UniProtKB/Swiss-Prot for SERPINA4 Gene
Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.