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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERPINA10 Gene

protein-coding   GIFtS: 52
GCID: GC14M094749

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,...

(Previous names: serine (or cysteine) proteinase inhibitor, clade A (alpha-1...)
 Explore 14 diseases affiliated with
SERPINA10 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for SERPINA10    

Aliases
for SERPINA10 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin),
Member 101 2
     Serpin A102 3
ZPI1 2 3 5     PZ-Dependent Protease Inhibitor2 3
PZI1 2 3     Protein Z-Dependent Protease Inhibitor2
Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase,
Antitrypsin), Member 101 2
     

External Ids:    HGNC: 159961   Entrez Gene: 511562   Ensembl: ENSG000001400937   OMIM: 6052715   UniProtKB: Q9UK553   

Export aliases for SERPINA10 gene to outside databases

Previous GC identifers: GC14M092256 GC14M088566 GC14M092739 GC14M093819 GC14M074929


Summaries
for SERPINA10 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SERPINA10:
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted
in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and
phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants
have been found for this gene.(provided by RefSeq, May 2010)

UniProtKB/Swiss-Prot: ZPI_HUMAN, Q9UK55
Function: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids




Genomic Views
for SERPINA10 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERPINA10 gene promoter:
         HOXA9B   HOXA9   Bach2   STAT3   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SERPINA10 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERPINA10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERPINA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.13   Ensembl cytogenetic band:  14q32.13   HGNC cytogenetic band: 14q32.13

SERPINA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERPINA10 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M094749:  view genomic region     (about GC identifiers)

Start:
 94,749,650 bp from pter      End:
 94,759,608 bp from pter
Size:
 9,959 bases      Orientation:
 minus strand

Proteins
for SERPINA10 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ZPI_HUMAN, Q9UK55 (See protein sequence)
Recommended Name: Protein Z-dependent protease inhibitor precursor  
Size: 444 amino acids; 50707 Da
Subunit: Interacts with PROZ
Subcellular location: Secreted
Sequence caution: Sequence=CAD62339.1; Type=Erroneous initiation;
4 PDB 3D structures from and Proteopedia for SERPINA10:
3F1S (3D)        3H5C (3D)        4AFX (3D)        4AJU (3D)    
Secondary accessions: A5Z2A5 Q6UWX9 Q86U20

Explore the universe of human proteins at neXtProt for SERPINA10: NX_Q9UK55

Post-translational modifications:

  • Phosphorylation sites are present in the extracellular medium1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UK55

    • SERPINA10 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001094077.1  NP_057270.1  

    ENSEMBL proteins: 
     ENSP00000450896   ENSP00000261994   ENSP00000450971   ENSP00000376809  

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    OriGene Protein Over-expression Lysate (see all 2): SERPINA10
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    Novus Biologicals SERPINA10 Protein
    Novus Biologicals SERPINA10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for SERPINA10

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--


    SERPINA10 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SERPINA10 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SERPINA10 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023796 Serpin_dom
     IPR000215 Serpin_fam

    Graphical View of Domain Structure for InterPro Entry Q9UK55

    ProtoNet protein and cluster: Q9UK55

    1 Blocks protein family: IPB000215 Serpin

    UniProtKB/Swiss-Prot: ZPI_HUMAN, Q9UK55
    Similarity: Belongs to the serpin family


    Function
    for SERPINA10 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ZPI_HUMAN, Q9UK55
    Function: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids

    miRNA
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    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERPINA10 (see all 7)
    OriGene shRNA RFP: SERPINA10
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    Gene Editing
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    Clone
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    In Situ Assay
    Products:       
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004867serine-type endopeptidase inhibitor activity IBA--


    SERPINA10 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for SERPINA10:
     Decreased number of cells in m  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-outs for SERPINA10: Serpina10tm1Gjb Serpina10tm1Lex
         4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Serpina10):
     cardiovascular system  homeostasis/metabolism  mortality/aging  nervous system 

    SERPINA10 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SERPINA10 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SERPINA10

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for SERPINA10 (Q9UK553 ENSP000002619944) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    F10P007423, ENSP000003647094I2D: score=1 STRING: ENSP00000364709
    PROZENSP000003646974STRING: ENSP00000364697
    PSMB7ENSP000002594574STRING: ENSP00000259457
    PIAS3ENSP000003767654STRING: ENSP00000376765
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007596blood coagulation IEA--
    GO:0010951negative regulation of endopeptidase activity IBA--
    GO:0030162regulation of proteolysis IBA--
    GO:0042246tissue regeneration ----
    GO:0060046NOT regulation of acrosome reaction IDA11751269


    SERPINA10 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SERPINA10 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SERPINA10 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERPINA10

    1 HMDB Compound for SERPINA10    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    5 Novoseek chemical compound relationships for SERPINA10 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phospholipid 55.2 8 19528533 (1), 18344422 (1), 10460162 (1), 18502758 (1) (see all 6)
    serine 27.9 8 19528533 (1), 18180611 (1)
    calcium 19.7 10 11341501 (1), 11487045 (1), 12911591 (1), 11372680 (1) (see all 7)
    alanine 3.44 1 10460162 (1)
    heparin 3.04 3 16079143 (2), 11049983 (1)

    Search CenterWatch for drugs/clinical trials and news about SERPINA10 / ZPI 

    Transcripts
    for SERPINA10 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SERPINA10 gene (2 alternative transcripts): 
    NM_001100607.2  NM_016186.2  

    Unigene Cluster for SERPINA10:

    Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
    Hs.118620  [show with all ESTs]
    Unigene Representative Sequence: NM_016186
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554723(uc001yct.3) ENST00000261994(uc001ycu.4) ENST00000554173
    ENST00000393096

    miRNA
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    Inhib. RNA
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    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERPINA10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERPINA10

    Additional cDNA sequence: 

    AF181467.1 AK314877.1 AY358597.1 BC022261.1 BX248011.1 

    4 DOTS entries:

    DT.100659432  DT.75113399  DT.100785135  DT.92043046 

    24/33 AceView cDNA sequences (see all 33):

    AI174900 CR606434 AF181467 AV681541 NM_016186 BC022261 BX496004 BX248011 
    BX496015 CB164232 CB161994 AY358597 AA779097 AI023884 AI183788 BX407966 
    AI040537 AA700364 BX429460 BX452425 AI052207 BX429624 AV649110 BX452424 

    GeneLoc Exon Structure


    Expression
    for SERPINA10 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERPINA10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GATAAGGGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    SERPINA10 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyLoop of HenleLoop of Henle CellsKidney
    PancreasIslets of LangerhansMature Beta CellsPancreas
    KidneyEpithelial TubuleKidney
    KidneyLoop of HenleKidney
    KidneyMetanephrosKidney
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See SERPINA10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERPINA10

    SOURCE GeneReport for Unigene cluster: Hs.118620

    UniProtKB/Swiss-Prot: ZPI_HUMAN, Q9UK55
    Tissue specificity: Expressed by the liver and secreted in plasma

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    In Situ
    Assay Products:     
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    Orthologs
    for SERPINA10 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SERPINA10 gene from 8/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SERPINA101 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, more 60.2(n)
    50.77(a)    		   423432  XM_421341.3  XP_421341.1 
    lizard
    (Anolis carolinensis)    		 Reptilia SERPINA106
    		 --
    		 50(a)
    		 1 ↔ 1
    		 1(6333329-6339570)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.119712 Transcribed sequence with weak similarity to protein more 70.75(n)    CF376175.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii serpina10a1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, more 49.17(n)
    30.66(a)    		   565064  NM_001045071.2  NP_001038536.2 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Spn66
    Spn42Dc6
    (see all 26)    		 Serpin 42Dc
    (see all 26)    		 26(a)
    24(a)
    (see all 26)    		 possible ortholog
    possible ortholog
    (see all 26)    		 2R(14013810-14015715)
    2R(2768501-2770912)
    worm
    (Caenorhabditis elegans)    		 Secernentea srp-16
    srp-26
    (see all 6)    		 SeRPin family member (srp-2)
    (see all 6)    		 24(a)
    22(a)
    (see all 6)    		 possible ortholog
    possible ortholog
    (see all 6)    		 V(753335-755049)
    V(762735-764658)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT2G252406
    AT3G452206
    (see all 10)    		 serpin-Z4
    (see all 10)    		 24(a)
    23(a)
    (see all 10)    		 many ↔ many
    many ↔ many
    (see all 10)    		 2(10751768-10753134)
    3(16564881-16566330)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    (see all 16)    		 serpin domain containing protein, putative, expres...
    serpin domain containing protein, putative, expres...
    (see all 16)    		 23(a)
    22(a)
    (see all 16)    		 many ↔ many
    many ↔ many
    (see all 16)    		 3(23053071-23066803)
    11(7423829-7425356)


    ENSEMBL Gene Tree for SERPINA10 (if available)
    TreeFam Gene Tree for SERPINA10 (if available) 

    Paralogs
    for SERPINA10 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERPINA10 gene
    SERPING12  SERPINA12  SERPINH12  SERPINA112  SERPINA72  SERPINA122  SERPINA92  SERPINA52  
    SERPINF12  SERPIND12  SERPINA42  SERPINA32  SERPINA62  SERPINF22  
    18/29 SIMAP similar genes for SERPINA10 using alignment to 2 protein entries:     ZPI_HUMAN (see all proteins) (see all similar genes):
    DKFZp686D06190    SERPINA6    SERPINA12    SERPINA3    SERPINA9    SERPINI2
    SERPINA5    SERPINB1    SERPINI1    DKFZp686O07189    SERPINA1    SERPINA2P
    SERPINB11    SERPINB12    SERPINB2    SERPINA7    SERPINB6    SERPINB7

    SERPINA10 for paralogs           About GeneDecksing



    Genomic Variants
    for SERPINA10 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/293 NCBI SNPs in SERPINA10 are shown (see all 293)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1483855971,2
    		C,F,other76880851(+) ATGAAG/AGCAAA 4 /A syn11Minor allele frequency- A:0.00NA 4506
    rs617544871,2
    		C,F,other76882641(+) CTGAGC/TCATGT 4 * W stg12Minor allele frequency- T:0.00NA EU 5873
    rs557974191,2
    		F--74929104(-) CTTGG-/CCAGAG 2 -- ds50012Minor allele frequency- C:0.09NS 90
    rs557036741,2
    		C,F,--74929199(-) ATCTAT/CTACGG 2 -- ds50014Minor allele frequency- C:0.05NS WA 210
    rs740759221,2
    		C,--74929499(+) ATCCAG/TGGTTT 2 -- ut311Minor allele frequency- T:0.50WA 2
    rs1138341031,2
    		--74929705(+) TCCTCG/ACCCAT 2 -- ut311Minor allele frequency- A:0.50CSA 2
    rs562359221,2
    		F--74929891(-) GACAGT/CGCTGA 2 -- ut312Minor allele frequency- C:0.02NS 92
    rs116227851,2
    		H--74930747(+) TCCCAA/GCACCT 2 -- int10--------
    rs791728311,2
    		--74930762(+) CTACTC/ATGAGG 2 -- int11Minor allele frequency- A:0.01WA 118
    rs740759311,2
    		C,--74930896(+) TACCTA/GTATAA 2 -- int12Minor allele frequency- G:0.03WA 120

    HapMap Linkage Disequilibrium report for SERPINA10 (94749650 - 94759608 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SERPINA10: --
    Human Gene Mutation Database (HGMD): SERPINA10

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    Disorders / Diseases
    for SERPINA10 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SERPINA10 for disorders           About GeneDecksing

    OMIM gene information: 605271    OMIM disorders: --

    14 diseases for SERPINA10:    About MalaCards
    venous thrombosis    thrombosis    central retinal artery occlusion    retinal artery occlusion
    protein c deficiency    thrombophilia    myocardial infarction    neuroendocrine carcinoma
    kidney disease    breast cancer    retinitis    carcinoma
    venous thromboembolism    thromboembolism

    3 Novoseek disease relationships for SERPINA10 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    venous thrombosis 38.5 5 15735788 (2), 15461625 (1)
    thrombosis 35.3 4 11487045 (1), 18344422 (1), 16527896 (1), 15461625 (1)
    thrombophilia 33.6 4 15461625 (2), 15735788 (1)

    Human Genome Epidemiology (HuGE) Navigator: SERPINA10 (5 documents)

    Export disorders for SERPINA10 gene to outside databases

    Publications
    for SERPINA10 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERPINA10 gene, integrated from 9 sources (see all 58):
    (articles sorted by number of sources associating them with SERPINA10)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The protein Z-dependent protease inhibitor is a serpin. (PubMed id 10460162)1, 2, 3, 9 Han X.... Broze G.J. Jr. (1999)
    2. Isolation of a protein Z-dependent plasma protease inhibitor. (PubMed id 9689066)1, 2, 3, 9 Han X.... Broze G.J. Jr. (1998)
    3. Characterization of the protein Z-dependent protease inhibitor. (PubMed id 11049983)1, 2, 9 Han X.... Broze G.J. Jr. (2000)
    4. Basis for the specificity and activation of the serpi n protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-as sociated factor Xa. (PubMed id 20427285)1, 2 Huang X....Gettins P.G. (2010)
    5. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    8. Mutations within the protein Z-dependent protease inhibitor gene are associated with venous thromboembolic disease: a new form of thrombophilia. (PubMed id 15461625)1, 9 Van de Water N....Harper P. (2004)
    9. Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor. (PubMed id 16093243)1, 9 Heeb M.J....Ruan L. (2005)
    10. A computational modeling and molecular dynamics study of the Michaelis complex of human protein Z-dependent protease inhibitor (ZPI) and factor Xa (FXa). (PubMed id 19172319)1, 9 Chandrasekaran V....Pedersen L.G. (2009)

    External Searches for SERPINA10 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SERPINA10 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51156 HGNC: 15996 AceView: SERPINA10 Ensembl:ENSG00000140093 euGenes: HUgn51156
    ECgene: SERPINA10 H-InvDB: SERPINA10

    Other Databases showing SERPINA10 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SERPINA10 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERPINA10 Pharmacogenomics, SNPs, Pathways
    SeattleSNPshttp://pga.gs.washington.edu/data/serpina10/

    Intellectual Property
    for SERPINA10 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SERPINA10 gene:
    Search GeneIP for patents involving SERPINA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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