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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

SERINC2 Gene

protein-coding GIFtS: 46
GCID: GC01P031883

serine incorporator 2

(Previous name: tumor differentially expressed 2-like )
(Previous symbol: TDE2L)

Explore 1 disease affiliated with
SERINC2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Serine Incorporator 2¹ ²		FKSG84¹
TDE2L¹ ² ³		Tumor Differentially Expressed 2-Like¹
PRO0899¹ ²		Tumor Differentially Expressed Protein 2²
TDE2¹ ²		Tumor Differentially Expressed Protein 2-Like³

External Ids:	HGNC: 23231¹	Entrez Gene: 347735²	Ensembl: ENSG00000168528⁷	OMIM: 614549⁵	UniProtKB: Q96SA4³

Export aliases for SERINC2 gene to outside databases

Previous GC identifers: GC01P031556 GC01P031659 GC01P030003

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the SERINC2 gene promoter:
Max1 Tal-1 Pax-2 AP-4 E47 AREB6 RORalpha1 POU2F1 POU2F1a c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: SERINC2 promoter sequence

Search SABiosciences Chromatin IP Primers for SERINC2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERINC2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.1 Ensembl cytogenetic band: 1p35.2 HGNC cytogenetic band: 1p35.1

SERINC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERINC2 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P031883: view genomic region (about GC identifiers)

Start:	31,882,412 bp from pter	End:	31,907,525 bp from pter
Size:	25,114 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: SERC2_HUMAN, Q96SA4 (See protein sequence)

Recommended Name: Serine incorporator 2

Size: 455 amino acids; 50742 Da

Subcellular location: Membrane; Multi-pass membrane protein (Potential)

Secondary accessions: A0AVB4 B4DJK5 B7Z567 B7ZAP2 Q86Y23

Alternative splicing: 3 isoforms: Q96SA4-1 Q96SA4-2 Q96SA4-3

Explore the universe of human proteins at neXtProt for SERINC2: NX_Q96SA4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96SA4

SERINC2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (5 alternative transcripts):

NP_001185966.1 NP_001185967.1 NP_001185968.1 NP_061035.2 NP_849196.2

ENSEMBL proteins:

ENSP00000362814 ENSP00000362813 ENSP00000444307 ENSP00000439048

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: SERINC2 OriGene Custom Protein Services for SERINC2
	GenScript Custom Purified and Recombinant Proteins Services for SERINC2
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for SERINC2

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016020	membrane	--	--
GO:0016021	integral to membrane	IEA	--

SERINC2 for ontologies About GeneDecksing

SERINC2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for SERINC2
	GenScript Custom Superior Antibodies Services for SERINC2
	Novus Biologicals SERINC2 Antibodies
	Search for Antibodies for SERINC2 at Abcam
	Uscn Antibodies for SERINC2
	Search ThermoFisher Antibodies for SERINC2

Assay Products for SERINC2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for SERINC2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for SERINC2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

SERINC2 for domains About GeneDecksing

1 InterPro domain/family:

IPR005016 TMS_TDE

Graphical View of Domain Structure for InterPro Entry Q96SA4

ProtoNet protein and cluster: Q96SA4

1 Blocks protein family: IPB005016 TMS membrane protein/tumour differentially expressed protein

UniProtKB/Swiss-Prot: SERC2_HUMAN, Q96SA4

Similarity: Belongs to the TDE1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: SERINC2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERINC2
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SERINC2 (see all 9):
		hsa-miR-3910 hsa-miR-4254 hsa-miR-124 hsa-miR-1303 hsa-miR-593* hsa-miR-506 hsa-miR-1264 hsa-miR-3622a-5p

		SwitchGear 3'UTR luciferase reporter plasmid: SERINC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERINC2 (see all 6) OriGene siRNA: SERINC2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERINC2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for SERINC2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 5): SERINC2 (NM_018565)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for SERINC2
		Search LifeMap BioReagents cell lines for SERINC2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for SERINC2

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for SERINC2
Search CenterWatch for drugs/clinical trials and news about SERINC2 / SERC2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for SERINC2 gene (5 alternative transcripts):

NM_001199037.1 NM_001199038.1 NM_001199039.1 NM_018565.3 NM_178865.4

Unigene Cluster for SERINC2:

Serine incorporator 2

Hs.270655 [show with all ESTs]

Unigene Representative Sequence: NM_001199039

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000373710(uc021okm.1) ENST00000487207 ENST00000373709(uc009vtw.1 uc001bst.3)

ENST00000491976(uc001bsu.3 uc010ogh.2) ENST00000536859(uc010ogg.2)

ENST00000536384

miRNA Products:		OriGene 3'-UTR Clone: SERINC2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERINC2
		8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate SERINC2 (see all 9):
		hsa-miR-3910 hsa-miR-4254 hsa-miR-124 hsa-miR-1303 hsa-miR-593* hsa-miR-506 hsa-miR-1264 hsa-miR-3622a-5p

		SwitchGear 3'UTR luciferase reporter plasmid: SERINC2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERINC2 (see all 6) OriGene siRNA: SERINC2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERINC2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 5): SERINC2 (NM_018565)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SERINC2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat SERINC2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERINC2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERINC2

Additional cDNA sequence:

AF352325.1 AK093784.1 AK127659.1 AK296118.1 AK298512.1 AK308031.1 AK309409.1 AK316357.1

AY094595.1 AY358560.1 BC007375.2 BC017085.1 BC063006.1 BC084580.1 BC126283.1 BC126285.1

18 DOTS entries:

DT.316537 DT.100758464 DT.95320485 DT.100823748 DT.100823754 DT.121451295 DT.40122005 DT.92406956

DT.92445896 DT.95320486 DT.97801492 DT.100728678 DT.101975303 DT.97859374 DT.100677018 DT.40247323

DT.95150676 DT.95153281

24/333 AceView cDNA sequences (see all 333):

CA487391 BU944634 CR619066 CR621050 CR605110 CR608200 BM744125 BG678618

CB120695 CR618465 CR620507 BQ954795 AL703499 CR606889 BQ953071 BM824140

CA489834 CR622064 CA454794 BM786140 CR626785 CR613892 CA454038 CR611236

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SERINC2 (see all 11) About this scheme

ExUns:	1	^	2	^	3a	·	3b	·	3c	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9a	·	9b	·	9c	^	10	^	11a	·	11b	·	11c	·	11d	^	12	^	13a	·	13b	^	14	^	15a	·	15b	·	15c	^
SP1:											-		-		-		-		-
SP2:											-		-		-		-		-
SP3:															-		-		-
SP4:			-		-		-		-		-		-		-		-		-
SP5:													-		-		-		-

ExUns:	16	^	17
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for SERINC2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

SERINC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGACGCTCA

About this image

SERINC2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Heart

Atrioventricular Node

Atrioventricular Node Cells

Myocardium

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See SERINC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SERINC2

SOURCE GeneReport for Unigene cluster: Hs.270655

SABiosciences Custom PCR Arrays for SERINC2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SERINC2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat SERINC2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERINC2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERINC2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for SERINC2 gene from 8/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	SERINC2¹	serine incorporator 2	72.48(n) 68.46(a)		419558 NM_001030890.1 NP_001026061.1
lizard (Anolis carolinensis)	Reptilia	SERINC2⁶	--	65(a)	1 ↔ 1	GL343563.1(189103-196743)
African clawed frog (Xenopus laevis)	Amphibia	BU913899.1²	--	72(n)		BU913899.1
zebrafish (Danio rerio)	Actinopterygii	CK026072.1²	--	72.55(n)		CK026072.1
fruit fly (Drosophila melanogaster)	Insecta	TMS1⁶	TMS1	36(a)	1 → many	3L(16405822-16408486)
worm (Caenorhabditis elegans)	Secernentea	R11H6.2⁶ Y57E12AL.1⁶	Protein Y57E12AL.1, isoform a	40(a) 39(a)	many ↔ many many ↔ many	V(14597924-14600076) V(7060791-7062799)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT3G06170⁶ AT1G16180⁶ (see all 5)	serinc-domain containing protein (see all 5)	28(a) 27(a) (see all 5)	many ↔ many many ↔ many (see all 5)	3(1867415-1869948) 1(5540427-5542902)
rice (Oryza sativa)	Liliopsida	-- -- (see all 4)	TMS membrane protein/tumour differentially express... TMS membrane protein/tumour differentially express... (see all 4)	28(a) 28(a) (see all 4)	many ↔ many many ↔ many (see all 4)	3(19517381-19524458) 2(33684870-33688279)

ENSEMBL Gene Tree for SERINC2 (if available)
TreeFam Gene Tree for SERINC2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for SERINC2 gene

ENSG00000262560² SERINC4² SERINC3² SERINC1² SERINC5²

4 SIMAP similar genes for SERINC2 using alignment to 5 protein entries: SERC2_HUMAN (see all proteins):

SERINC1 SERINC3 SERINC5 SERINC4

SERINC2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs113213458^1,2	C,F,	--	29991502(+)	`TAGTGG/TGTTGG`	1	--	us2k¹		1		NA	120
rs191350033^1,2		--	31880450(+)	`CTCCCA/GGGTTC`	1	--	us2k¹		0	--	--	--	--
rs7532872^1,2	C,A,H,	--	31880584(+)	`ACTCCG/CGACCT`	1	--	us2k¹ tfbs³		2		NA	4
rs182848591^1,2		--	31880604(+)	`CGCCCA/GCCTTG`	1	--	us2k¹		0	--	--	--	--
rs7532881^1,2	C,A,H,	--	31880605(+)	`GCCCGT/CCTTGG`	1	--	us2k¹		2		NA	4
rs141402305^1,2		--	31880614(+)	`GGCCTC/TCCAAA`	1	--	us2k¹		0	--	--	--	--
rs74878227^1,2	C	--	31880827(+)	`AGATCG/TTCACA`	1	--	us2k¹		0	--	--	--	--
rs145179576^1,2		--	31880914(+)	`ATTCTA/GTTCTT`	1	--	us2k¹		0	--	--	--	--
rs146844068^1,2		--	31880927(+)	`CATCTC/TATCCA`	1	--	us2k¹		0	--	--	--	--
rs117793405^1,2	F,	--	31881152(+)	`TATCCA/GTCTAC`	2	--	us2k¹		1		EA	120

HapMap Linkage Disequilibrium report for SERINC2 (31882412 - 31907525 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 8 variations for SERINC2
7 CNVs: 84167 74437 2304 74436 84168 3287 74438
1 Indel: 68350

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERINC2

DNA2.0 Custom Variant and Variant Library Synthesis for SERINC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

SERINC2 for disorders           About GeneDecksing

OMIM gene information: 614549    OMIM disorders: --

1 disease for SERINC2:    About MalaCards

lung cancer

Export disorders for SERINC2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for SERINC2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with SERINC2)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Identification of TDE2 gene and its expression in non-small cell lung cancer. (PubMed id 12949800)^{1, 3} Player A....Jen J. (2003)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)¹ Hillier L.W....Wilson R.K. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )² Aoki H.... Hino O. (2000)
Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)¹ Nagase T.... Ohara O. (1998)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 347735	HGNC: 23231	AceView: TDE2L	Ensembl:ENSG00000168528	euGenes: HUgn347735
ECgene: SERINC2	H-InvDB: SERINC2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for SERINC2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SERINC2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for SERINC2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for SERINC2 gene:
Search GeneIP for patents involving SERINC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SERINC2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SERINC2
	OriGene Protein Over-expression Lysate for SERINC2		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for SERINC2		OriGene 3'-UTR Clone for SERINC2
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SERINC2
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	OriGene Custom Antibody Services for SERINC2		OriGene Custom Protein Services for SERINC2
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SERINC2
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SERINC2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERINC2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERINC2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERINC2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERINC2

	GenScript Custom Purified and Recombinant Proteins Services for SERINC2		GenScript cDNA clones with any tag delivered in your preferred vector for SERINC2
	GenScript Custom Assay Services for SERINC2		GenScript Custom Superior Antibodies Services for SERINC2
	GenScript Custom overexpressing Cell Line Services for SERINC2		CloneReady with Over 120,000 Genes
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	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in SERINC2 promoter
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC2

	SwitchGear 3'UTR luciferase reporter plasmids for SERINC2
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Search ThermoFisher Antibodies for SERINC2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC2

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes SERINC2 gene at Home site.

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SERINC2 Gene

serine incorporator 2

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SERINC2 Gene

serine incorporator 2

Aliasesfor SERINC2 gene

Summariesfor SERINC2 gene

Genomic Viewsfor SERINC2 gene

Proteinsfor SERINC2 gene

Protein Domains /Familiesfor SERINC2 gene

Functionfor SERINC2 gene

Pathways & Interactionsfor SERINC2 gene

Drugs & Compoundsfor SERINC2 gene

Transcriptsfor SERINC2 gene

Expression for SERINC2 gene

Orthologsfor SERINC2 gene

Paralogsfor SERINC2 gene

Genomic Variantsfor SERINC2 gene

Disorders / Diseasesfor SERINC2 gene

Publicationsfor SERINC2 gene

External Searches for SERINC2 gene

Genome Databases showing SERINC2 gene

Other Databases showing SERINC2 gene

Specialized Databases showing SERINC2 gene

Intellectual Propertyfor SERINC2 gene

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Aliases
for SERINC2 gene

Summaries
for SERINC2 gene

Genomic Views
for SERINC2 gene

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for SERINC2 gene

Protein Domains /
Families
for SERINC2 gene

Function
for SERINC2 gene

Pathways & Interactions
for SERINC2 gene

Drugs & Compounds
for SERINC2 gene

Transcripts
for SERINC2 gene

Expression
for SERINC2 gene

Orthologs
for SERINC2 gene

Paralogs
for SERINC2 gene

Genomic Variants
for SERINC2 gene

Disorders / Diseases
for SERINC2 gene

Publications
for SERINC2 gene

Intellectual Property
for SERINC2 gene

Products
for SERINC2 gene