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SERINC2 Gene

protein-coding   GIFtS: 48
GCID: GC01P031883

Serine Incorporator 2

(Previous name: tumor differentially expressed 2-like)
(Previous symbol: TDE2L)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Serine Incorporator 21 2     TDE22
TDE2L1 2 3     Tumor Differentially Expressed Protein 22
Tumor Differentially Expressed 2-Like1     Tumor Differentially Expressed Protein 2-Like3
PRO08992     

External Ids:    HGNC: 232311   Entrez Gene: 3477352   Ensembl: ENSG000001685287   OMIM: 6145495   UniProtKB: Q96SA43   

Export aliases for SERINC2 gene to outside databases

Previous GC identifers: GC01P031556 GC01P031659 GC01P030003


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for SERINC2 Gene:
SERINC2 (serine incorporator 2) is a protein-coding gene. An important paralog of this gene is SERINC4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the SERINC2 gene promoter:
         Max1   Tal-1   Pax-2   AP-4   E47   AREB6   RORalpha1   POU2F1   POU2F1a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERINC2 promoter sequence
   Search Chromatin IP Primers for SERINC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SERINC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.1   Ensembl cytogenetic band:  1p35.2   HGNC cytogenetic band: 1p35.1

SERINC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERINC2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P031883:  view genomic region     (about GC identifiers)

Start:
31,882,412 bp from pter      End:
31,907,527 bp from pter
Size:
25,116 bases      Orientation:
plus strand

1 alternative location:
Chr1+,NW_003571030 9,654-34,769     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SERC2_HUMAN, Q96SA4 (See protein sequence)
Recommended Name: Serine incorporator 2  
Size: 455 amino acids; 50742 Da
Secondary accessions: A0AVB4 B4DJK5 B7Z567 B7ZAP2 E7EUZ9 Q86Y23
Alternative splicing: 4 isoforms:  Q96SA4-1   Q96SA4-2   Q96SA4-3   Q96SA4-4   (No experimental confirmation available. Gene prediction based on cDNA data)

Explore the universe of human proteins at neXtProt for SERINC2: NX_Q96SA4

Explore proteomics data for SERINC2 at MOPED


See SERINC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts): 
NP_001185966.1  NP_001185967.1  NP_001185968.1  NP_061035.2  NP_849196.2  

ENSEMBL proteins: 
 ENSP00000362814   ENSP00000362813   ENSP00000444307   ENSP00000439048  

SERINC2 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for SERINC2
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Novus Biologicals SERINC2 Protein
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for SERINC2

 
Search eBioscience for Proteins for SERINC2 

 
antibodies-online proteins for SERINC2 

 
antibodies-online peptides for SERINC2

SERINC2 Antibody Products:

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Abcam antibodies for SERINC2
Cloud-Clone Corp. Antibodies for SERINC2
Search ThermoFisher Antibodies for SERINC2
antibodies-online antibodies for SERINC2 (22 products) 

SERINC2 Assay Products:

Browse Kits and Assays available from EMD Millipore
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Cloud-Clone Corp. ELISAs for SERINC2
Cloud-Clone Corp. CLIAs for SERINC2
Search eBioscience for ELISAs for SERINC2 
antibodies-online kits for SERINC2 (6 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR005016 TMS_TDE

Graphical View of Domain Structure for InterPro Entry Q96SA4

ProtoNet protein and cluster: Q96SA4

1 Blocks protein domain: IPB005016 TMS membrane protein/tumour differentially expressed protein

UniProtKB/Swiss-Prot: SERC2_HUMAN, Q96SA4
Similarity: Belongs to the TDE1 family


Find genes that share domains with SERINC2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for SERINC2

miRNA
Products:
    
miRTarBase miRNAs that target SERINC2:
hsa-mir-335-5p (MIRT016907)

Block miRNA regulation of human, mouse, rat SERINC2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SERINC2 (see all 9):
hsa-miR-3910 hsa-miR-4254 hsa-miR-124 hsa-miR-1303 hsa-miR-593* hsa-miR-506 hsa-miR-1264 hsa-miR-3622a-5p
SwitchGear 3'UTR luciferase reporter plasmidSERINC2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for SERINC2
Predesigned siRNA for gene silencing in human, mouse, rat SERINC2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for SERINC2

Clone
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OriGene clones in human, mouse for SERINC2 (see all 16)
OriGene ORF clones in mouse, rat for SERINC2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 5): SERINC2 (NM_018565)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for SERINC2
Browse ESI BIO Cell Lines and PureStem Progenitors for SERINC2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
SERC2_HUMAN, Q96SA4: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3
extracellular1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016020membrane ----
GO:0016021integral component of membrane IEA--
GO:0070062extracellular vesicular exosome IDA19056867

Find genes that share ontologies with SERINC2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SERINC2
Interactions:

    Search GeneGlobe Interaction Network for SERINC2

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

3 Interacting proteins for SERINC2 (ENSP000003628134) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
TMEM50AENSP000003634784STRING: ENSP00000363478
RTN3ENSP000003441064STRING: ENSP00000344106
--ENSP000003713904STRING: ENSP00000371390
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006658phosphatidylserine metabolic process IEA--
GO:0051347positive regulation of transferase activity IEA--

Find genes that share ontologies with SERINC2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for SERINC2 (SERC2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for SERINC2 gene (5 alternative transcripts): 
NM_001199037.1  NM_001199038.1  NM_001199039.1  NM_018565.3  NM_178865.4  

Unigene Cluster for SERINC2:

Serine incorporator 2
Hs.270655  [show with all ESTs]
Unigene Representative Sequence: NM_001199039
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000373710(uc021okm.1) ENST00000487207 ENST00000373709(uc009vtw.1 uc001bst.3)
ENST00000491976(uc001bsu.3 uc010ogh.2) ENST00000536859(uc010ogg.2)
ENST00000536384
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat SERINC2 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate SERINC2 (see all 9):
hsa-miR-3910 hsa-miR-4254 hsa-miR-124 hsa-miR-1303 hsa-miR-593* hsa-miR-506 hsa-miR-1264 hsa-miR-3622a-5p
SwitchGear 3'UTR luciferase reporter plasmidSERINC2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for SERINC2
Predesigned siRNA for gene silencing in human, mouse, rat SERINC2
Clone
Products:
     
OriGene clones in human, mouse for SERINC2 (see all 16)
OriGene ORF clones in mouse, rat for SERINC2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 5): SERINC2 (NM_018565)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERINC2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERINC2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for SERINC2
OriGene qSTAR qPCR primer pairs in human, mouse for SERINC2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SERINC2
  QuantiTect SYBR Green Assays in human, mouse, rat SERINC2
  QuantiFast Probe-based Assays in human, mouse, rat SERINC2

Additional mRNA sequence: 

AF352325.1 AK093784.1 AK127659.1 AK296118.1 AK298512.1 AK308031.1 AK309409.1 AK316357.1 
AY094595.1 AY358560.1 BC007375.2 BC017085.1 BC063006.1 BC084580.1 BC126283.1 BC126285.1 

18 DOTS entries:

DT.316537  DT.100758464  DT.95320485  DT.100823748  DT.100823754  DT.121451295  DT.40122005  DT.92406956 
DT.92445896  DT.95320486  DT.97801492  DT.100728678  DT.101975303  DT.97859374  DT.100677018  DT.40247323 
DT.95150676  DT.95153281 

Selected AceView cDNA sequences (see all 333):

BM824140 CR608912 CA454794 CA489834 BQ954795 CR613892 CA489562 CA453941 
CR626785 CB142107 CR620507 CR608200 CR619066 BM786140 BM744125 CB120695 
AW452938 CA454038 CR606889 CA487391 CR618465 CR608538 CR605110 CR622064 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for SERINC2 (see all 11)    About this scheme

ExUns: 1 ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c · 11d ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b · 15c ^
SP1:                                -     -     -     -     -                                                                                                   
SP2:                                -     -     -     -     -                                                                                                   
SP3:                                            -     -     -                                                                                                   
SP4:        -     -     -     -     -     -     -     -     -                                                                                                   
SP5:                                      -     -     -     -                                                                                                   

ExUns: 16 ^ 17
SP1:            
SP2:            
SP3:            
SP4:            
SP5:            


ECgene alternative splicing isoforms for SERINC2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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SERINC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATGACGCTCA
SERINC2 Expression
About this image


SERINC2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 7) fully expand
 
 Heart (Cardiovascular System)
         Atrioventricular Node Cells Atrioventricular Node
 
 Colon (Gastrointestinal Tract)
 
 Esophagus (Gastrointestinal Tract)
 
 Gall Bladder (Hepatobiliary System)
 
 Placenta (Extraembryonic Tissues)
SERINC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

SERINC2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.270655
    Custom PCR Arrays for SERINC2
Primer
Products:
OriGene qPCR primer pairs and template standards for SERINC2
OriGene qSTAR qPCR primer pairs in human, mouse for SERINC2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat SERINC2
QuantiTect SYBR Green Assays in human, mouse, rat SERINC2
QuantiFast Probe-based Assays in human, mouse, rat SERINC2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERINC2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for SERINC2 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Serinc21 , 5 serine incorporator 21, 5 84.89(n)1
86.89(a)1
  4 (63.43 cM)5
2307791  NM_172702.31  NP_766290.21 
 1302534955 
chicken
(Gallus gallus)
Aves SERINC21 serine incorporator 2 72.87(n)
68.61(a)
  419558  NM_001030890.1  NP_001026061.1 
lizard
(Anolis carolinensis)
Reptilia SERINC26
serine incorporator 2
65(a)
1 ↔ 1
GL343563.1(188923-196743)
African clawed frog
(Xenopus laevis)
Amphibia BU913899.12   -- 72(n)    BU913899.1 
zebrafish
(Danio rerio)
Actinopterygii CK026072.12   -- 72.55(n)    CK026072.1 
fruit fly
(Drosophila melanogaster)
Insecta TMS16
TMS1
37(a)
1 → many
3L(16405822-16408486)
worm
(Caenorhabditis elegans)
Secernentea R11H6.26
Y57E12AL.16
Protein R11H6.2 (R11H6.2) mRNA, complete cds
Protein Y57E12AL.1, isoform a (Y57E12AL.1) mRNA, c...
40(a)
39(a)
many ↔ many
many ↔ many
V(14597939-14600091) WBGene00011250
V(7060811-7062817) WBGene00021956
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TMS16
Vacuolar membrane protein of unknown function that...
25(a)
1 → many
IV(665349-666770) YDR105C


ENSEMBL Gene Tree for SERINC2 (if available)
TreeFam Gene Tree for SERINC2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for SERINC2 gene
SERINC42  SERINC12  SERINC32  SERINC52  
4 SIMAP similar genes for SERINC2 using alignment to 4 protein entries:     SERC2_HUMAN (see all proteins):
SERINC1    SERINC3    SERINC5    SERINC4

Find genes that share paralogs with SERINC2           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for SERINC2 (see all 782)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1132134581,2
C,F--29991502(+) TAGTGG/TGTTGG 1 -- us2k11Minor allele frequency- T:0.02NA 120
rs1485260351,2
--29991542(+) AGGTAC/TGGCAT 1 -- us2k10--------
rs1902613941,2
C--29991601(+) AAGAGA/GAGGGC 1 -- us2k10--------
rs1811340971,2
--29991647(+) AGCACC/TTTGGG 1 -- us2k10--------
rs722238471,2
C--30000013(+) TTTGT-/TTG   
  T
/TTTG
TTGTT
2 -- int10--------
rs1913500331,2
--31880450(+) CTCCCA/GGGTTC 1 -- us2k10--------
rs75328721,2
C,A,H--31880584(+) ACTCCG/CGACCT 1 -- us2k1 tfbs32Minor allele frequency- C:0.25NA 4
rs1828485911,2
--31880604(+) CGCCCA/GCCTTG 1 -- us2k10--------
rs75328811,2
C,A,H--31880605(+) GCCCGT/CCTTGG 1 -- us2k12Minor allele frequency- C:0.25NA 4
rs1414023051,2
C--31880614(+) GGCCTC/TCCAAA 1 -- us2k10--------

HapMap Linkage Disequilibrium report for SERINC2 (31882412 - 31907527 bp)

Structural Variations
     Database of Genomic Variants (DGV) 9 variations for SERINC2:    About this table    
Variant IDTypeSubtypePubMed ID
esv2746352CNV Deletion23290073
esv2746341CNV Deletion23290073
esv1004118CNV Insertion20482838
esv1133300CNV Insertion17803354
nsv7712CNV Insertion18451855
nsv509135CNV Insertion20534489
esv1676191CNV Insertion17803354
esv21814CNV Gain19812545
dgv46e1CNV Complex17122850

Human Gene Mutation Database (HGMD): SERINC2
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing SERINC2
DNA2.0 Custom Variant and Variant Library Synthesis for SERINC2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 614549    OMIM disorders: --


Find genes that share disorders with SERINC2           About GenesLikeMe


Export disorders for SERINC2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for SERINC2 gene, integrated from 10 sources (see all 13):
(articles sorted by number of sources associating them with SERINC2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Identification of TDE2 gene and its expression in non-small cell lung cancer. (PubMed id 12949800)1, 3 Player A....Jen J. (Int. J. Cancer 2003)
  4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
  5. Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent. (PubMed id 23778322)1 Zuo L....Luo X. (Pharmacogenet. Genomics 2013)
  6. NKAIN1-SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent. (PubMed id 23455491)1 Zuo L....Luo X. (Drug Alcohol Depend 2013)
  7. Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways. (PubMed id 21752829)1 Palmieri M....Ballabio A. (Hum. Mol. Genet. 2011)
  8. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
  9. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
  10. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1 Hillier L.W.... Wilson R.K. (Nature 2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 347735 HGNC: 23231 AceView: TDE2L Ensembl:ENSG00000168528 euGenes: HUgn347735
ECgene: SERINC2 H-InvDB: SERINC2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for SERINC2 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for SERINC2 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for SERINC2 gene:
Search GeneIP for patents involving SERINC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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