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Aliases for SERHL Gene

Aliases for SERHL Gene

  • Serine Hydrolase-Like (Pseudogene) 2 3
  • Kraken-Like 2 3
  • Serine Hydrolase-Like 2
  • DJ222E13.1 3
  • EC 3.1.-.- 4
  • BK126B4.1 3
  • BK126B4.2 3
  • HS126B42 3
  • SERHL2 4
  • SHL 4

External Ids for SERHL Gene

Previous GeneCards Identifiers for SERHL Gene

  • GC22P039499
  • GC22P041127
  • GC22P041221
  • GC22P042896
  • GC22P025862

Summaries for SERHL Gene

GeneCards Summary for SERHL Gene

SERHL (Serine Hydrolase-Like (Pseudogene)) is a Pseudogene. GO annotations related to this gene include hydrolase activity.

UniProtKB/Swiss-Prot for SERHL Gene

  • Putative serine hydrolase

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SERHL Gene

Genomics for SERHL Gene

Regulatory Elements for SERHL Gene

Genomic Location for SERHL Gene

Start:
42,500,579 bp from pter
End:
42,512,560 bp from pter
Size:
11,982 bases
Orientation:
Plus strand

Genomic View for SERHL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for SERHL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SERHL Gene

Proteins for SERHL Gene

  • Protein details for SERHL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQF3-SERHL_HUMAN
    Recommended name:
    Serine hydrolase-like protein
    Protein Accession:
    Q9NQF3
    Secondary Accessions:
    • Q5JZ95
    • Q9UH21

    Protein attributes for SERHL Gene

    Size:
    203 amino acids
    Molecular mass:
    22471 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene may have been partially duplicated (see SERHL2)

neXtProt entry for SERHL Gene

Proteomics data for SERHL Gene at MOPED

Post-translational modifications for SERHL Gene

No Post-translational modifications

No data available for DME Specific Peptides for SERHL Gene

Domains for SERHL Gene

Protein Domains for SERHL Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SERHL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NQF3

UniProtKB/Swiss-Prot:

SERHL_HUMAN :
  • Q9NQF3
Family:
  • Belongs to the AB hydrolase superfamily.
genes like me logo Genes that share domains with SERHL: view

No data available for Gene Families for SERHL Gene

Function for SERHL Gene

Molecular function for SERHL Gene

UniProtKB/Swiss-Prot Function: Putative serine hydrolase

Enzyme Numbers (IUBMB) for SERHL Gene

Gene Ontology (GO) - Molecular Function for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with SERHL: view

miRNA for SERHL Gene

miRTarBase miRNAs that target SERHL

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SERHL

In Situ Assay Products

Flow Cytometry Products

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for SERHL Gene

Localization for SERHL Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SERHL Gene COMPARTMENTS Subcellular localization image for SERHL gene
Compartment Confidence
peroxisome 3
nucleus 2
cytosol 1
extracellular 1

Gene Ontology (GO) - Cellular Components for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with SERHL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for SERHL Gene

Pathways for SERHL Gene

SuperPathways for SERHL Gene

No Data Available

Interacting Proteins for SERHL Gene

Gene Ontology (GO) - Biological Process for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with SERHL: view

No data available for Pathways by source for SERHL Gene

Transcripts for SERHL Gene

mRNA/cDNA for SERHL Gene

Unigene Clusters for SERHL Gene

Serine hydrolase-like:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for SERHL

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for SERHL
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SERHL Gene

No ASD Table

Relevant External Links for SERHL Gene

GeneLoc Exon Structure for
SERHL
ECgene alternative splicing isoforms for
SERHL

Expression for SERHL Gene

mRNA expression in normal human tissues for SERHL Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for SERHL Gene Hs.360940

genes like me logo Genes that share expressions with SERHL: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for SERHL Gene

Orthologs for SERHL Gene

This gene was present in the common ancestor of animals.

Orthologs for SERHL Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta CG7632 37
  • 32 (a)
kraken 37
  • 33 (a)
CG15820 37
  • 30 (a)
CG11309 37
  • 31 (a)
CG15879 37
  • 30 (a)
Species with no ortholog for SERHL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SERHL Gene

ENSEMBL:
Gene Tree for SERHL (if available)
TreeFam:
Gene Tree for SERHL (if available)

Paralogs for SERHL Gene

Selected SIMAP similar genes for SERHL Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SERHL: view

No data available for Paralogs for SERHL Gene

Variants for SERHL Gene

Sequence variations from dbSNP and Humsavar for SERHL Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs137012 -- 42,505,687(+) CATAT(C/T)TGTTG intron-variant
rs137013 -- 42,505,779(+) CATGC(A/C)ATCGA intron-variant
rs137014 -- 42,505,782(+) GCAAT(C/T)GAAAC intron-variant
rs881542 -- 42,499,994(+) ggagg(C/G)cgagg upstream-variant-2KB
rs2003669 -- 42,506,821(+) GGTAG(A/C)ACATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for SERHL Gene

Variant ID Type Subtype PubMed ID
dgv1407e1 CNV Complex 17122850
nsv428391 CNV Gain 18775914
essv4940 CNV CNV 17122850
esv32632 CNV Gain 17666407
esv2724283 CNV Deletion 23290073
esv28197 CNV Gain 19812545
nsv9912 CNV Gain+Loss 18304495
nsv829246 CNV Loss 20364138
dgv773n67 CNV Gain 20364138
dgv103e180 CNV Gain 20482838
essv20414 CNV CNV 17122850
dgv781e201 CNV Deletion 23290073
nsv442798 CNV CNV 18776908
esv2659886 CNV Deletion 23128226

Relevant External Links for SERHL Gene

HapMap Linkage Disequilibrium report
SERHL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SERHL Gene

Disorders for SERHL Gene

No disorders were found for SERHL Gene.

No data available for UniProtKB/Swiss-Prot for SERHL Gene

Publications for SERHL Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  2. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PMID: 12529303) Collins J.E. … Dunham I. (Genome Res. 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Identification of Serhl, a new member of the serine hydrolase family induced by passive stretch of skeletal muscle in vivo. (PMID: 11352564) Sadusky T.J. … Coulton G.R. (Genomics 2001) 2

Products for SERHL Gene

Sources for SERHL Gene

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