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Aliases for SERHL Gene

Aliases for SERHL Gene

  • Serine Hydrolase-Like (Pseudogene) 2 3 5
  • Kraken-Like 2 3
  • Serine Hydrolase-Like 2
  • DJ222E13.1 3
  • EC 3.1.-.- 4
  • BK126B4.1 3
  • BK126B4.2 3
  • HS126B42 3
  • SERHL2 4
  • SHL 4

External Ids for SERHL Gene

Previous GeneCards Identifiers for SERHL Gene

  • GC22P039499
  • GC22P041127
  • GC22P041221
  • GC22P042896
  • GC22P025862

Summaries for SERHL Gene

GeneCards Summary for SERHL Gene

SERHL (Serine Hydrolase-Like (Pseudogene)) is a Pseudogene. GO annotations related to this gene include hydrolase activity.

UniProtKB/Swiss-Prot for SERHL Gene

  • Putative serine hydrolase.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SERHL Gene

Genomics for SERHL Gene

Regulatory Elements for SERHL Gene

Enhancers for SERHL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around SERHL on UCSC Golden Path with GeneCards custom track

Genomic Location for SERHL Gene

Chromosome:
22
Start:
42,500,579 bp from pter
End:
42,512,560 bp from pter
Size:
11,982 bases
Orientation:
Plus strand

Genomic View for SERHL Gene

Genes around SERHL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SERHL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SERHL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SERHL Gene

Proteins for SERHL Gene

  • Protein details for SERHL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQF3-SERHL_HUMAN
    Recommended name:
    Serine hydrolase-like protein
    Protein Accession:
    Q9NQF3
    Secondary Accessions:
    • Q5JZ95
    • Q9UH21

    Protein attributes for SERHL Gene

    Size:
    203 amino acids
    Molecular mass:
    22471 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This gene may have been partially duplicated (see SERHL2).

neXtProt entry for SERHL Gene

Post-translational modifications for SERHL Gene

No Post-translational modifications

No data available for DME Specific Peptides for SERHL Gene

Domains & Families for SERHL Gene

Protein Domains for SERHL Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for SERHL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NQF3

UniProtKB/Swiss-Prot:

SERHL_HUMAN :
  • Belongs to the AB hydrolase superfamily.
Family:
  • Belongs to the AB hydrolase superfamily.
genes like me logo Genes that share domains with SERHL: view

No data available for Gene Families for SERHL Gene

Function for SERHL Gene

Molecular function for SERHL Gene

UniProtKB/Swiss-Prot Function:
Putative serine hydrolase.

Enzyme Numbers (IUBMB) for SERHL Gene

Gene Ontology (GO) - Molecular Function for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0016787 hydrolase activity IBA --
genes like me logo Genes that share ontologies with SERHL: view
genes like me logo Genes that share phenotypes with SERHL: view

Animal Model Products

miRNA for SERHL Gene

miRTarBase miRNAs that target SERHL

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for SERHL Gene

Localization for SERHL Gene

Gene Ontology (GO) - Cellular Components for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005739 mitochondrion IBA --
genes like me logo Genes that share ontologies with SERHL: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for SERHL Gene

Pathways & Interactions for SERHL Gene

SuperPathways for SERHL Gene

No Data Available

Interacting Proteins for SERHL Gene

Selected Interacting proteins: Q9NQF3-SERHL_HUMAN for SERHL Gene via IID

Symbol External ID(s) Details
TFAP2A

Gene Ontology (GO) - Biological Process for SERHL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with SERHL: view

No data available for Pathways by source and SIGNOR curated interactions for SERHL Gene

Drugs & Compounds for SERHL Gene

No Compound Related Data Available

Transcripts for SERHL Gene

mRNA/cDNA for SERHL Gene

Unigene Clusters for SERHL Gene

Serine hydrolase-like:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for SERHL Gene

No ASD Table

Relevant External Links for SERHL Gene

GeneLoc Exon Structure for
SERHL
ECgene alternative splicing isoforms for
SERHL

Expression for SERHL Gene

mRNA expression in normal human tissues for SERHL Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of SERHL Gene:

SERHL

SOURCE GeneReport for Unigene cluster for SERHL Gene:

Hs.360940
genes like me logo Genes that share expression patterns with SERHL: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for SERHL Gene

Orthologs for SERHL Gene

This gene was present in the common ancestor of animals.

Orthologs for SERHL Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta CG11309 36
  • 31 (a)
CG15820 36
  • 30 (a)
CG15879 36
  • 30 (a)
CG7632 36
  • 32 (a)
kraken 36
  • 33 (a)
Species where no ortholog for SERHL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for SERHL Gene

ENSEMBL:
Gene Tree for SERHL (if available)
TreeFam:
Gene Tree for SERHL (if available)

Paralogs for SERHL Gene

(1) SIMAP similar genes for SERHL Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with SERHL: view

No data available for Paralogs for SERHL Gene

Variants for SERHL Gene

Sequence variations from dbSNP and Humsavar for SERHL Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
VAR_056985 -
rs881542 -- 42,499,994(+) ggagg(C/G)cgagg upstream-variant-2KB
rs6002770 -- 42,500,030(+) ttcga(A/G)accag upstream-variant-2KB
rs28432165 -- 42,501,023(+) CAGCT(C/G)TGGGG intron-variant
rs35641002 -- 42,498,778(+) CAACC(A/G)GTTAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for SERHL Gene

Variant ID Type Subtype PubMed ID
dgv101e203 CNV gain+loss 21179565
dgv103e180 CNV gain 20482838
dgv1321e212 CNV gain 25503493
dgv173n111 CNV duplication 26073780
dgv174n111 CNV duplication 26073780
dgv175n111 CNV duplication 26073780
dgv4576n100 CNV gain 25217958
dgv4577n100 CNV gain 25217958
dgv4578n100 CNV gain 25217958
dgv4579n100 CNV gain+loss 25217958
dgv4580n100 CNV gain+loss 25217958
dgv4581n100 CNV gain 25217958
dgv4582n100 CNV gain+loss 25217958
dgv4583n100 CNV gain+loss 25217958
dgv4584n100 CNV gain 25217958
dgv4585n100 CNV gain 25217958
dgv734e201 CNV deletion 23290073
dgv773n67 CNV gain 20364138
dgv8117n54 CNV gain 21841781
dgv842e214 CNV gain 21293372
esv2659886 CNV deletion 23128226
esv2724283 CNV deletion 23290073
esv2758839 CNV gain+loss 17122850
esv28197 CNV gain 19812545
esv32632 CNV gain 17666407
esv3568421 CNV loss 25503493
esv3575487 CNV gain 25503493
esv3575488 CNV gain 25503493
esv3647819 CNV gain 21293372
esv3647831 CNV loss 21293372
nsv1055597 CNV gain 25217958
nsv1056323 CNV loss 25217958
nsv1062078 CNV loss 25217958
nsv1064178 CNV gain 25217958
nsv1160770 CNV duplication 26073780
nsv1160775 CNV deletion 26073780
nsv428391 CNV gain 18775914
nsv442798 CNV gain+loss 18776908
nsv589065 CNV gain 21841781
nsv589071 CNV loss 21841781
nsv829246 CNV loss 20364138
nsv9912 CNV gain+loss 18304495

Relevant External Links for SERHL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
SERHL

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for SERHL Gene

Disorders for SERHL Gene

Relevant External Links for SERHL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SERHL

No disorders were found for SERHL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for SERHL Gene

Publications for SERHL Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  2. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PMID: 12529303) Collins J.E. … Dunham I. (Genome Res. 2003) 3 4 65
  3. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4 65
  4. Genome-wide association study identified copy number variants important for appendicular lean mass. (PMID: 24626161) Ran S. … Deng H.W. (PLoS ONE 2014) 3 65
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65

Products for SERHL Gene

Sources for SERHL Gene

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