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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SERBP1 Gene

protein-coding   GIFtS: 51
GCID: GC01M067873

SERPINE1 MRNA Binding Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
SERPINE1 MRNA Binding Protein 11 2     HABP4L2
PAI-RBP12 3     Chromodomain Helicase DNA Binding Protein 3 Interacting Protein2
PAIRBP12 3     PAI-1 MRNA Binding Protein2
PAI1 RNA-Binding Protein 12 3     Plasminogen Activator Inhibitor 1 RNA Binding Protein2
SERPINE1 MRNA-Binding Protein 12 3     Plasminogen Activator Inhibitor 1 RNA-Binding Protein2
CHD3IP2     

External Ids:    HGNC: 178601   Entrez Gene: 261352   Ensembl: ENSG000001428647   OMIM: 6073785   UniProtKB: Q8NC513   

Export aliases for SERBP1 gene to outside databases

Previous GC identifers: GC01M067590 GC01M065983


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for SERBP1 Gene: 
SERBP1 (SERPINE1 mRNA binding protein 1) is a protein-coding gene. Diseases associated with SERBP1 include sertoli cell-only syndrome, and abdominal aortic aneurysm. GO annotations related to this gene include protein binding and mRNA 3'-UTR binding. An important paralog of this gene is HABP4.

UniProtKB/Swiss-Prot: PAIRB_HUMAN, Q8NC51
Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1
mRNA, a region which confers cyclic nucleotide regulation of message decay

Gene Wiki entry for SERBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SERBP1 gene promoter:
         AhR   FOXF2   Bach2   Pax-2   Pax-4a   Tal-1beta   Arnt   Ik-1   E47   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidSERBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for SERBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SERBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31   Ensembl cytogenetic band:  1p31.3   HGNC cytogenetic band: 1p31

SERBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SERBP1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M067873:  view genomic region     (about GC identifiers)

Start:
67,873,493 bp from pter      End:
67,896,123 bp from pter
Size:
22,631 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PAIRB_HUMAN, Q8NC51 (See protein sequence)
Recommended Name: Plasminogen activator inhibitor 1 RNA-binding protein  
Size: 408 amino acids; 44965 Da
Subunit: Interacts with CHD3 and TDRD3
Subcellular location: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Also found in perinuclear regions
1 PDB 3D structure from and Proteopedia for SERBP1:
3J3A (3D)    
Secondary accessions: Q5VU19 Q5VU20 Q5VU22 Q8WUH0 Q96SE2 Q9BTY3 Q9BUM4 Q9Y367 Q9Y4S3
Alternative splicing: 4 isoforms:  Q8NC51-1   Q8NC51-2   Q8NC51-3   Q8NC51-4   (Contains a phosphoserine at position 231. Contains a phosphothreonine at position 234)

Explore the universe of human proteins at neXtProt for SERBP1: NX_Q8NC51

Explore proteomics data for SERBP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NC51

  • SERBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SERBP1 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001018077.1  NP_001018078.1  NP_001018079.1  NP_056455.3  

    ENSEMBL proteins: 
     ENSP00000360033   ENSP00000360034   ENSP00000354591   ENSP00000360029  

    Human Recombinant Protein Products for SERBP1: 
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    Novus Biologicals SERBP1 Lysates
    Browse Sino Biological Recombinant Proteins
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    Cloud-Clone Corp. Proteins for SERBP1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IEA--
    GO:0048471perinuclear region of cytoplasm IEA--

    SERBP1 for ontologies           About GeneDecksing



    SERBP1 Antibody Products: 
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    Assay Products for SERBP1: 
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    Cloud-Clone Corp. ELISAs for SERBP1 
    Cloud-Clone Corp. CLIAs for SERBP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR027205 SERBP1
     IPR006861 HABP4_PAIRBP1-bd

    Graphical View of Domain Structure for InterPro Entry Q8NC51

    ProtoNet protein and cluster: Q8NC51


    SERBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PAIRB_HUMAN, Q8NC51
    Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1
    mRNA, a region which confers cyclic nucleotide regulation of message decay

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003730mRNA 3'-UTR binding IDA11001948
    GO:0005515protein binding IPI12505151
         
    SERBP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for SERBP1:
     Decreased Hepatitis C virus re 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SERBP1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SERBP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SERBP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SERBP1 

    miRNA
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    miRTarBase miRNAs that target SERBP1:
    hsa-mir-26a (MIRT002315)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SERBP1
    8/154 QIAGEN miScript miRNA Assays for microRNAs that regulate SERBP1 (see all 154):
    hsa-miR-579 hsa-miR-100* hsa-miR-128 hsa-miR-605 hsa-miR-3653 hsa-miR-138-2* hsa-miR-3921 hsa-miR-298
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Gene Editing
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    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERBP1
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERBP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SERBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/92 Interacting proteins for SERBP1 (Q8NC511, 2, 3 ENSP000003600344) via UniProtKB, MINT, STRING, and/or I2D (see all 92)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITFG1Q8TB962, 3, ENSP000003199184MINT-8270209 I2D: score=2 STRING: ENSP00000319918
    VIMP086702, 3MINT-64988 I2D: score=4 
    DAXXQ9UER73, ENSP000003968764I2D: score=1 STRING: ENSP00000396876
    ENSG00000206206Q9UER73I2D: score=1 
    ENSG00000206279Q9UER73I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043488regulation of mRNA stability NAS11001948

    SERBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SERBP1 (PAIRB)

    Search CenterWatch for drugs/clinical trials and news about SERBP1 / PAIRB

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SERBP1 gene (4 alternative transcripts): 
    NM_001018067.1  NM_001018068.1  NM_001018069.1  NM_015640.3  

    Unigene Cluster for SERBP1:

    SERPINE1 mRNA binding protein 1
    Hs.530412  [show with all ESTs]
    Unigene Representative Sequence: NM_001018067
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370994(uc001ddy.3 uc001ddw.3 uc001ddx.3 uc001ddv.3)
    ENST00000370995 ENST00000361219 ENST00000370990 ENST00000493607 ENST00000462814
    ENST00000484880 ENST00000490406
    miRNA
    Products:
         
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    8/154 QIAGEN miScript miRNA Assays for microRNAs that regulate SERBP1 (see all 154):
    hsa-miR-579 hsa-miR-100* hsa-miR-128 hsa-miR-605 hsa-miR-3653 hsa-miR-138-2* hsa-miR-3921 hsa-miR-298
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for SERBP1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SERBP1
    Clone
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    OriGene clones in human, mouse for SERBP1 (see all 29)
    OriGene ORF clones in mouse, rat for SERBP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): SERBP1 (NM_001018069)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for SERBP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SERBP1
    Sirion Biotech Customized lentivirus for stable overexpression of SERBP1 
                         Customized lentivirus expression plasmids for stable overexpression of SERBP1 
    Primer
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    OriGene qPCR primer pairs and template standards for SERBP1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SERBP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SERBP1

    Additional mRNA sequence: 

    AF131807.1 AF151813.1 AK074970.1 AK095960.1 AK130606.1 AK222955.1 AK223138.1 AK312256.1 
    AL080119.1 AY032853.1 BC002488.2 BC003049.1 BC008045.2 BC017449.1 BC019273.1 BC020555.1 
    BC026916.1 BC036414.2 BX647139.1 CR457383.1 

    24/63 DOTS entries (see all 63):

    DT.452915  DT.87015541  DT.100891205  DT.91699359  DT.100891225  DT.92360428  DT.100891198  DT.100040476 
    DT.100891222  DT.100891221  DT.100033842  DT.101985402  DT.443183  DT.121263321  DT.102838737  DT.100680339 
    DT.100891213  DT.121335052  DT.91718737  DT.121335097  DT.100891189  DT.100891214  DT.92467919  DT.101969765 

    24/1440 AceView cDNA sequences (see all 1440):

    AA035739 BQ421077 BE220410 AA456286 AA961611 CA394500 AA353066 CB115013 
    CR619466 AA580859 CR623194 N54677 BU902164 AI590932 AA760844 BM750429 
    BQ690962 CR607610 BC020555 BU687013 CA950380 BU159606 BQ001885 BU175375 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SERBP1 expression in normal human tissues (normalized intensities)      SERBP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    SERBP1 Expression
    About this image


    SERBP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/35 selected tissues (see all 35) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See SERBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SERBP1

    SOURCE GeneReport for Unigene cluster: Hs.530412

    UniProtKB/Swiss-Prot: PAIRB_HUMAN, Q8NC51
    Tissue specificity: Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in
    placenta, liver and brain

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SERBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for SERBP1 gene from 8/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Serbp11 , 5 serpine1 mRNA binding protein 11, 5 93.26(n)1
    98.7(a)1
      6 (30.80 cM)5
    668701  NM_001113566.11  NP_001107038.11 
     672669795 
    chicken
    (Gallus gallus)
    Aves SERBP11 SERPINE1 mRNA binding protein 1 78.18(n)
    86.75(a)
      424706  NM_001031293.1  NP_001026464.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    89(a)
    82(a)
    1 ↔ many
    1 ↔ many
    GL344316.1(2505-11083)
    GL343328.1(47025-93471)
    African clawed frog
    (Xenopus laevis)
    Amphibia rda288-prov2 hypothetical protein MGC53445 77.78(n)    BC046574.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.3832 Danio rerio mRNA similar to RIKEN cDNA 1200009K13 gene more 79.11(n)    BC046876.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG415031 CG41503 50.37(n)
    42.86(a)
      8674077  NM_001170392.3  NP_001163863.3 
    worm
    (Caenorhabditis elegans)
    Secernentea vig-11 Protein VIG-1 42.58(n)
    35.01(a)
      173512  NM_170974.2  NP_740971.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g05896001 hypothetical protein 51.52(n)
    43.83(a)
      4339782  NM_001063018.1  NP_001056483.1 


    ENSEMBL Gene Tree for SERBP1 (if available)
    TreeFam Gene Tree for SERBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SERBP1 gene
    HABP42  
    2 SIMAP similar genes for SERBP1 using alignment to 3 protein entries:     PAIRB_HUMAN (see all proteins):
    DKFZp686P17171    HABP4

    SERBP1 for paralogs           About GeneDecksing


    5/8 Pseudogenes.org Pseudogenes for SERBP1 (see all 8)
    PGOHUM00000237501 PGOHUM00000244079 PGOHUM00000237630 PGOHUM00000245605 PGOHUM00000235205


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/472 SNPs in SERBP1 are shown (see all 472)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1857244731,2
    --67873042(+) GTGGCA/GGGCGC 4 -- ds50010--------
    rs1162357051,2
    F--67873058(+) ATTCTA/GGCTAC 4 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1878632341,2
    --67873159(+) CAGAGA/TGAGAC 4 -- ds50010--------
    rs1924451561,2
    --67873295(+) ATGTCA/GTCATG 4 -- ds50010--------
    rs19485261,2
    C,F,O,A,H--67873346(-) TTTTGG/TAAAGA 4 -- ds500117Minor allele frequency- T:0.02NA EA MN NS 1702
    rs19485251,2
    C,F,H--67873451(-) ACAAAG/AAAATG 4 -- ds500111Minor allele frequency- A:0.01MN NS EA NA 1504
    rs1841058921,2
    --67873459(+) TGTGGA/GTTACG 4 -- ds50010--------
    rs1887396501,2
    --67873464(+) GTTACA/GTGTAA 4 -- ds50010--------
    rs1815171091,2
    --67873486(+) CAATAC/TACAAA 4 -- ds50010--------
    rs1845640541,2
    --67873492(+) ACAAAA/GTTCCC 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for SERBP1 (67873493 - 67896123 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SERBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv1254CNV Insertion18451855
    nsv461773CNV Loss19166990
    nsv871374CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607378    OMIM disorders: --

    12 diseases for SERBP1:    About MalaCards
    sertoli cell-only syndrome    abdominal aortic aneurysm    aortic aneurysm    kaposi's sarcoma
    crohn's disease    ovarian cancer    asthma    pancreatic cancer
    sarcoma    pancreatitis    prostate cancer    prostatitis


    SERBP1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): SERBP1

    Export disorders for SERBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SERBP1 gene, integrated from 9 sources (see all 84):
    (articles sorted by number of sources associating them with SERBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the type-1 plasminogen activator inhibitor mRNA. (PubMed id 11001948)1, 2, 3, 9 Heaton J.H.... Gelehrter T.D. (2001)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2, 3 Lai C.H....Lin W. (2000)
    3. Expression analysis and RNA localization of PAI-RBP1 (SERBP1) in epithelial ovarian cancer: association with tumor progression. (PubMed id 17698176)1, 3, 9 Koensgen D....Sehouli J. (2007)
    4. Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3. (PubMed id 12505151)1, 2, 9 Lemos T.A.... Kobarg J. (2003)
    5. TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules. (PubMed id 18632687)1, 2, 9 Goulet I.... Cote J. (2008)
    6. Expression of progesterone receptor membrane component 1 and its partner serpine 1 mRNA binding protein in uterine and placental tissues of the mouse and human. (PubMed id 18440126)1, 3 Zhang L....Pru J.K. (2008)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26135 HGNC: 17860 AceView: PAI-RBP1 Ensembl:ENSG00000142864 euGenes: HUgn26135
    ECgene: SERBP1 H-InvDB: SERBP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SERBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SERBP1 gene:
    Search GeneIP for patents involving SERBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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