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Aliases for SEPT9 Gene

Aliases for SEPT9 Gene

  • Septin 9 2 3 5
  • Ov/Br Septin 2 3 4
  • MLL Septin-Like Fusion Protein MSF-A 3 4
  • Ovarian/Breast Septin 3 4
  • Septin D1 3 4
  • MSF 3 4
  • MLL Septin-Like Fusion Protein 4
  • MLL Septin-Like Fusion 2
  • KIAA0991 4
  • AF17q25 3
  • PNUTL4 3
  • SeptD1 3
  • SINT1 3
  • NAPB 3
  • MSF1 3

External Ids for SEPT9 Gene

Previous HGNC Symbols for SEPT9 Gene

  • MSF

Previous GeneCards Identifiers for SEPT9 Gene

  • GC17P072790
  • GC17P075277
  • GC17P070710

Summaries for SEPT9 Gene

Entrez Gene Summary for SEPT9 Gene

  • This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009]

GeneCards Summary for SEPT9 Gene

SEPT9 (Septin 9) is a Protein Coding gene. Diseases associated with SEPT9 include amyotrophy, hereditary neuralgic and camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Among its related pathways are Bacterial invasion of epithelial cells and ERK Signaling. GO annotations related to this gene include nucleotide binding and GTPase activity. An important paralog of this gene is SEPT6.

UniProtKB/Swiss-Prot for SEPT9 Gene

  • Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Gene Wiki entry for SEPT9 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for SEPT9 Gene

Genomics for SEPT9 Gene

Regulatory Elements for SEPT9 Gene

Enhancers for SEPT9 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around SEPT9 on UCSC Golden Path with GeneCards custom track

Promoters for SEPT9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around SEPT9 on UCSC Golden Path with GeneCards custom track

Genomic Location for SEPT9 Gene

Chromosome:
17
Start:
77,280,569 bp from pter
End:
77,500,596 bp from pter
Size:
220,028 bases
Orientation:
Plus strand

Genomic View for SEPT9 Gene

Genes around SEPT9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
SEPT9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for SEPT9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for SEPT9 Gene

Proteins for SEPT9 Gene

  • Protein details for SEPT9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UHD8-SEPT9_HUMAN
    Recommended name:
    Septin-9
    Protein Accession:
    Q9UHD8
    Secondary Accessions:
    • A8K2V3
    • B3KPM0
    • B4DTL9
    • B4E0N2
    • B4E274
    • B7Z654
    • Q96QF3
    • Q96QF4
    • Q96QF5
    • Q9HA04
    • Q9UG40
    • Q9Y5W4

    Protein attributes for SEPT9 Gene

    Size:
    586 amino acids
    Molecular mass:
    65401 Da
    Quaternary structure:
    • Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments, and microtubules. GTPase activity is required for filament formation. Interacts with SEPT2, SEPT6, SEPT7, SEPT11 and SEPT14. Interacts with RTKN and ARHGEF18. In a mesenchymal cell line, Rho/RTKN signals cause disruption of wild-type septin filaments, but not of those containing isoform 2 variants HNA Trp-106 and Phe-111. In a mesenchymal cell line, isoform 2 variants HNA Trp-106 and Phe-111, but not wild type, form filaments with SEPT4.
    SequenceCaution:
    • Sequence=BAB14057.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305};

    Alternative splice isoforms for SEPT9 Gene

neXtProt entry for SEPT9 Gene

Proteomics data for SEPT9 Gene at MOPED

Post-translational modifications for SEPT9 Gene

  • Ubiquitination at Lys 186, Lys 262, Lys 271, Lys 326, Lys 343, Lys 352, Lys 357, Lys 381, Lys 389, Lys 431, Lys 435, Lys 445, Lys 476, Lys 490, Lys 511, Lys 519, and Lys 549
  • Modification sites at PhosphoSitePlus

Antibody Products

No data available for DME Specific Peptides for SEPT9 Gene

Domains & Families for SEPT9 Gene

Gene Families for SEPT9 Gene

Protein Domains for SEPT9 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UHD8

UniProtKB/Swiss-Prot:

SEPT9_HUMAN :
  • Contains 1 septin-type G (guanine nucleotide-binding) domain.
  • Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Domain:
  • Contains 1 septin-type G (guanine nucleotide-binding) domain.
Family:
  • Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
genes like me logo Genes that share domains with SEPT9: view

No data available for Suggested Antigen Peptide Sequences for SEPT9 Gene

Function for SEPT9 Gene

Molecular function for SEPT9 Gene

UniProtKB/Swiss-Prot Function:
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
genes like me logo Genes that share phenotypes with SEPT9: view

Human Phenotype Ontology for SEPT9 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for SEPT9 Gene

MGI Knock Outs for SEPT9:

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for SEPT9 Gene

Localization for SEPT9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for SEPT9 Gene

Cytoplasm, cytoskeleton. Note=In an epithelial cell line, concentrates at cell-cell contact areas. After TGF-beta1 treatment and induction of epithelial to mesenchymal transition, colocalizes partly with actin stress fibers. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for SEPT9 Gene COMPARTMENTS Subcellular localization image for SEPT9 gene
Compartment Confidence
cytoskeleton 4
nucleus 3
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for SEPT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001725 stress fiber IDA 15485874
GO:0031513 nonmotile primary cilium IDA 23572511
GO:0048471 perinuclear region of cytoplasm IDA 15485874
genes like me logo Genes that share ontologies with SEPT9: view

Pathways & Interactions for SEPT9 Gene

genes like me logo Genes that share pathways with SEPT9: view

Pathways by source for SEPT9 Gene

1 KEGG pathway for SEPT9 Gene
2 Qiagen pathways for SEPT9 Gene

SIGNOR curated interactions for SEPT9 Gene

Inactivates:
Is inactivated by:

Gene Ontology (GO) - Biological Process for SEPT9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0051291 protein heterooligomerization IDA 15485874
genes like me logo Genes that share ontologies with SEPT9: view

Drugs & Compounds for SEPT9 Gene

(1) Additional Compounds for SEPT9 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with SEPT9: view

Transcripts for SEPT9 Gene

Unigene Clusters for SEPT9 Gene

Septin 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for SEPT9 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c · 8d ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^
SP1: - - - - - - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - - -
SP4: - - - - - - -
SP5: - - -
SP6:
SP7:
SP8:
SP9:
SP10: - - - - - - - - - -
SP11: - - - - - - - - - - - - - - -
SP12:
SP13:
SP14:
SP15:
SP16:
SP17: - - - - - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - - - -
SP19: - - - - - - - - - - - - - - -
SP20: - - - - - - - - - - - - - - - - - - - -
SP21:
SP22:
SP23: - - - - - - - - - - - - - - - - - - - - - - -
SP24: - - - - - - - - -
SP25: - - - - - -
SP26: - - - - - -
SP27: - - - - - - - - - - - - - - - - - - -
SP28:
SP29:
SP30:
SP31:
SP32: - - - - - - - - - - - - - - - - - - - - - -
SP33: - - - - - - - - - -
SP34: - - - -
SP35: - - - - - - - - - - - - - - - - -
SP36: - -
SP37: -

ExUns: 17 ^ 18 ^ 19a · 19b · 19c ^ 20a · 20b ^ 21a · 21b · 21c · 21d · 21e · 21f · 21g ^ 22 ^ 23a · 23b · 23c · 23d ^ 24 ^ 25a · 25b · 25c · 25d ^ 26 ^ 27 ^
SP1: - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - -
SP3: - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - -
SP6: - - - - - - - - - - - - - -
SP7: - - - - - - - -
SP8:
SP9: - - -
SP10: - - - - - - - - - - - - - - - - - - -
SP11: - - - - - - - - - - - - - - - - - - - - - - - - -
SP12: - - - - - - - - - - -
SP13: - - - - - - -
SP14: -
SP15:
SP16:
SP17: - -
SP18: - -
SP19: - - - - - - - - - - - - - - - - - - - - - - - - - -
SP20: - -
SP21: - - - - - - -
SP22: - - -
SP23: - -
SP24: - - - - - - - - - - - - - - - - - - - - - - - - - -
SP25: - -
SP26: - - - - - - - - - - - - - -
SP27: - -
SP28: -
SP29:
SP30: - -
SP31:
SP32: - -
SP33: - - - - -
SP34: - -
SP35: - -
SP36: - -
SP37: - -

ExUns: 28 ^ 29 ^ 30a · 30b · 30c ^ 31 ^ 32a · 32b · 32c ^ 33a · 33b ^ 34 ^ 35 ^ 36a · 36b · 36c ^ 37 ^ 38a · 38b ^ 39a · 39b ^ 40a · 40b
SP1: - - - -
SP2: - - - -
SP3: - - - -
SP4: - - - -
SP5: - - - -
SP6: - - - -
SP7: - - - -
SP8: - -
SP9: - -
SP10: - - - - - -
SP11: - - -
SP12: - -
SP13: - -
SP14: - -
SP15:
SP16: -
SP17:
SP18:
SP19: - -
SP20:
SP21: - -
SP22: - -
SP23:
SP24: - - - - - - - - - - - - - -
SP25:
SP26: - -
SP27:
SP28:
SP29:
SP30: - -
SP31:
SP32:
SP33:
SP34:
SP35:
SP36:
SP37:

Relevant External Links for SEPT9 Gene

GeneLoc Exon Structure for
SEPT9
ECgene alternative splicing isoforms for
SEPT9

Expression for SEPT9 Gene

mRNA expression in normal human tissues for SEPT9 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for SEPT9 Gene



SOURCE GeneReport for Unigene cluster for SEPT9 Gene Hs.440932

mRNA Expression by UniProt/SwissProt for SEPT9 Gene

Q9UHD8-SEPT9_HUMAN
Tissue specificity: Widely expressed. Isoforms are differentially expressed in testes, kidney, liver heart, spleen, brain, peripheral blood leukocytes, skeletal muscle and kidney. Specific isoforms appear to demonstrate tissue specificity. Isoform 5 is the most highly expressed in fetal tissue. Isoform 1 is detected in all tissues except the brain and thymus, while isoform 2, isoform 3, and isoform 4 are detected at low levels in approximately half of the fetal tissues.
genes like me logo Genes that share expression patterns with SEPT9: view

Protein tissue co-expression partners for SEPT9 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein differential expression in normal tissues for SEPT9 Gene

Orthologs for SEPT9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for SEPT9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia SEPT9 35
  • 90.43 (n)
  • 92.82 (a)
SEPT9 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia SEPT9 35
  • 89.83 (n)
  • 92.65 (a)
SEPT9 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Sept9 35
  • 86.6 (n)
  • 90.72 (a)
Sept9 16
Sept9 36
  • 90 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Sept9 35
  • 86.48 (n)
  • 90.13 (a)
oppossum
(Monodelphis domestica)
Mammalia SEPT9 36
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia SEPT9 36
  • 90 (a)
OneToOne
chicken
(Gallus gallus)
Aves SEPT9 35
  • 76.96 (n)
  • 80.61 (a)
SEPT9 36
  • 77 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia SEPT9 36
  • 68 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia sept9 35
  • 69.65 (n)
  • 72.58 (a)
Str.14028 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.8325 35
zebrafish
(Danio rerio)
Actinopterygii msf 35
sept9a 35
  • 64.34 (n)
  • 64.87 (a)
sept9a 36
  • 55 (a)
OneToMany
sept9b 36
  • 79 (a)
OneToMany
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6451 35
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AAR001C 35
  • 57.83 (n)
  • 48.66 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F12848g 35
  • 53.94 (n)
  • 49.65 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CDC10 35
  • 50.93 (n)
  • 47.22 (a)
CDC3 36
  • 27 (a)
OneToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU03515 35
  • 61.37 (n)
  • 51.35 (a)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes spn2 35
  • 52.06 (n)
  • 48.38 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8439 36
  • 54 (a)
OneToMany
Species with no ortholog for SEPT9:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for SEPT9 Gene

ENSEMBL:
Gene Tree for SEPT9 (if available)
TreeFam:
Gene Tree for SEPT9 (if available)

Paralogs for SEPT9 Gene

genes like me logo Genes that share paralogs with SEPT9: view

Variants for SEPT9 Gene

Sequence variations from dbSNP and Humsavar for SEPT9 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
VAR_020667 -
rs34587622 - 77,402,416(+) AGAAC(C/G/T)GGCCC reference, missense, utr-variant-5-prime
rs2627223 - 77,498,623(-) CTCCA(C/T)GCCGT reference, missense
VAR_033101 Hereditary neuralgic amyotrophy (HNA)
VAR_033102 Hereditary neuralgic amyotrophy (HNA)

Structural Variations from Database of Genomic Variants (DGV) for SEPT9 Gene

Variant ID Type Subtype PubMed ID
esv34174 CNV Loss 18971310
dgv1000e1 CNV Complex 17122850
nsv833551 CNV Gain 17160897
nsv908842 CNV Loss 21882294
nsv833552 CNV Loss 17160897
esv992724 CNV Deletion 20482838
nsv517339 CNV Loss 19592680
nsv908844 CNV Loss 21882294
nsv908845 CNV Loss 21882294
nsv908846 CNV Loss 21882294
nsv457914 CNV Loss 19166990
nsv525375 CNV Loss 19592680
nsv457915 CNV Gain 19166990
nsv525851 CNV Loss 19592680
esv2716278 CNV Deletion 23290073
esv1080795 CNV Deletion 17803354
esv2716279 CNV Deletion 23290073
nsv908847 CNV Loss 21882294
nsv908848 CNV Loss 21882294
nsv111673 CNV Loss 16902084
nsv908849 CNV Loss 21882294
nsv513483 CNV Insertion 21212237
nsv908850 CNV Loss 21882294
dgv3274n71 CNV Loss 21882294
nsv908853 CNV Loss 21882294
esv34184 CNV Loss 18971310
esv2670792 CNV Deletion 23128226
nsv908855 CNV Loss 21882294
nsv2150 CNV Insertion 18451855
esv274097 CNV Insertion 20981092
esv2716280 CNV Deletion 23290073
esv2378475 CNV Deletion 18987734
dgv569e199 CNV Deletion 23128226
esv3114 CNV Deletion 18987735
esv996321 CNV Deletion 20482838
esv2716281 CNV Deletion 23290073
esv1440775 CNV Deletion 17803354
esv1001835 CNV Loss 20482838
nsv526477 CNV Loss 19592680

Variation tolerance for SEPT9 Gene

Residual Variation Intolerance Score: 25.7% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for SEPT9 Gene

HapMap Linkage Disequilibrium report
SEPT9
Human Gene Mutation Database (HGMD)
SEPT9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for SEPT9 Gene

Disorders for SEPT9 Gene

MalaCards: The human disease database

(7) MalaCards diseases for SEPT9 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
amyotrophy, hereditary neuralgic
  • amyotrophic neuralgia
camptodactyly-arthropathy-coxa vara-pericarditis syndrome
  • cdags syndrome
amyotrophic neuralgia
  • neuralgic amyotrophy
brachial plexus neuropathy
  • brachial plexopathy
brachial plexus neuritis
  • brachial neuritis
- elite association - COSMIC cancer census association via MalaCards
Search SEPT9 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

SEPT9_HUMAN
  • Hereditary neuralgic amyotrophy (HNA) [MIM:162100]: Autosomal dominant form of recurrent focal neuropathy characterized clinically by acute, recurrent episodes of brachial plexus neuropathy with muscle weakness and atrophy preceded by severe pain in the affected arm. HNA is triggered by environmental factors such as infection or parturition. {ECO:0000269 PubMed:16186812, ECO:0000269 PubMed:17546647, ECO:0000269 PubMed:18492087, ECO:0000269 PubMed:19451530}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Note=A chromosomal aberration involving SEPT9/MSF is found in therapy-related acute myeloid leukemia (t-AML). Translocation t(11;17)(q23;q25) with KMT2A/MLL1. {ECO:0000269 PubMed:10339604}.

Relevant External Links for SEPT9

Genetic Association Database (GAD)
SEPT9
Human Genome Epidemiology (HuGE) Navigator
SEPT9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
SEPT9
genes like me logo Genes that share disorders with SEPT9: view

No data available for Genatlas for SEPT9 Gene

Publications for SEPT9 Gene

  1. MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25). (PMID: 10339604) Osaka M. … Zeleznik-Le N.J. (Proc. Natl. Acad. Sci. U.S.A. 1999) 2 3 4 23 67
  2. AF17q25, a putative septin family gene, fuses the MLL gene in acute myeloid leukemia with t(11;17)(q23;q25). (PMID: 10485469) Taki T. … Hayashi Y. (Cancer Res. 1999) 2 3 23
  3. Phenotypic spectrum of hereditary neuralgic amyotrophy caused by the SEPT9 R88W mutation. (PMID: 20019224) Ueda M. … Kira J.I. (J. Neurol. Neurosurg. Psychiatr. 2010) 3 23
  4. Targeted knockdown of SEPT9_v1 inhibits tumor growth and angiogenesis of human prostate cancer cells concomitant with disruption of hypoxia-inducible factor-1 pathway. (PMID: 20407014) Amir S. … Mabjeesh N.J. (Mol. Cancer Res. 2010) 3 23
  5. Up-regulation of SEPT9_v1 stabilizes c-Jun-N-terminal kinase and contributes to its pro-proliferative activity in mammary epithelial cells. (PMID: 19071215) Gonzalez M.E. … Petty E.M. (Cell. Signal. 2009) 3 23

Products for SEPT9 Gene

Sources for SEPT9 Gene

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