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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEPT8 Gene

protein-coding   GIFtS: 56
GCID: GC05M132086

Septin 8

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Septin 81 2
KIAA02023 5
SEP22
septin-82

External Ids:    HGNC: 165111   Entrez Gene: 231762   Ensembl: ENSG000001644027   OMIM: 6084185   UniProtKB: Q925993   

Export aliases for SEPT8 gene to outside databases

Previous GC identifers: GC05M131608 GC05M132533 GC05M132117 GC05M132162 GC05M132114 GC05M127279


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for SEPT8 Gene:
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell
division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to
regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large
multinucleate or polyploid cells. (provided by RefSeq, Jun 2012)

GeneCards Summary for SEPT8 Gene: 
SEPT8 (septin 8) is a protein-coding gene. Diseases associated with SEPT8 include parkinson's disease, and retinitis. GO annotations related to this gene include protein binding and GTP binding. An important paralog of this gene is SEPT3.

UniProtKB/Swiss-Prot: SEPT8_HUMAN, Q92599
Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May
play a role in platelet secretion

Gene Wiki entry for SEPT8 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NT_034772.6  NC_018916.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEPT8 gene promoter:
         AREB6   c-Fos   AP-1   c-Jun   Nkx5-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SEPT8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEPT8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31   Ensembl cytogenetic band:  5q31.1   HGNC cytogenetic band: 5q31

SEPT8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEPT8 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M132086:  view genomic region     (about GC identifiers)

Start:
132,086,509 bp from pter      End:
132,142,933 bp from pter
Size:
56,425 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SEPT8_HUMAN, Q92599 (See protein sequence)
Recommended Name: Septin-8  
Size: 483 amino acids; 55756 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with
cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By
similarity). Interacts with CDK14, SEPT4, SEPT5 and SEPT7 (By similarity)
Subcellular location: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=In platelets, found
in areas surrounding alpha-granules
Sequence caution: Sequence=AAG09407.1; Type=Erroneous initiation; Sequence=AAH01329.1; Type=Erroneous initiation;
Sequence=AAO13878.1; Type=Erroneous initiation; Sequence=AAO13879.1; Type=Erroneous initiation;
Sequence=AAO13880.1; Type=Erroneous initiation; Sequence=BAA13193.1; Type=Erroneous initiation;
Secondary accessions: A6NC65 A6NKP6 Q8IX36 Q8IX37 Q9BVB3
Alternative splicing: 3 isoforms:  Q92599-1   Q92599-2   Q92599-3   (KIAA0202a differs from KIAA0202c at the level of the 3'-UTR)

Explore the universe of human proteins at neXtProt for SEPT8: NX_Q92599

Explore proteomics data for SEPT8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92599

  • SEPT8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    SEPT8 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001092281.1  NP_001092282.1  NP_001092283.1  NP_055961.1  

    ENSEMBL proteins: 
     ENSP00000367991   ENSP00000367993   ENSP00000296873   ENSP00000367978   ENSP00000367971  
     ENSP00000367973   ENSP00000394766   ENSP00000407421   ENSP00000411823   ENSP00000360548  
     ENSP00000399840  

    Human Recombinant Protein Products for SEPT8: 
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    Novus Biologicals SEPT8 Protein
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0031105septin complex IEA--

    SEPT8 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    SEPT: Septins

    3 InterPro protein domains:
     IPR000038 Cell_div_GTP-bd
     IPR027417 P-loop_NTPase
     IPR016491 Septin

    Graphical View of Domain Structure for InterPro Entry Q92599

    ProtoNet protein and cluster: Q92599

    1 Blocks protein domain: IPB000038 Cell division/GTP binding protein

    UniProtKB/Swiss-Prot: SEPT8_HUMAN, Q92599
    Similarity: Belongs to the septin family


    SEPT8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SEPT8_HUMAN, Q92599
    Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May
    play a role in platelet secretion

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17685441
    GO:0005525GTP binding IEA--
         
    SEPT8 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for SEPT8:
     Decreased p24 protein expressi  Decreased viability of wild-ty 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Sept8):
     behavior/neurological  growth/size  hematopoietic system  homeostasis/metabolism  immune system 

    SEPT8 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for SEPT8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for SEPT8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEPT8 
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    miRNA
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    hsa-miR-30c hsa-miR-520d-5p hsa-miR-30d hsa-miR-183* hsa-miR-30a hsa-miR-4325 hsa-miR-520g hsa-miR-556-3p
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for SEPT8 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Bacterial invasion of epithelial cells
    Bacterial invasion of epithelial cells

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for SEPT8):
        Bacterial invasion of epithelial cells


    SEPT8 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SEPT8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/38 Interacting proteins for SEPT8 (Q925992, 3 ENSP000003679914) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    A2MP010232, 3MINT-8270143 I2D: score=2 
    KMT2BQ9UMN62, 3MINT-8270154 I2D: score=2 
    PHF17Q6IE812, 3MINT-8270165 I2D: score=2 
    PPHLN1Q8NEY82, 3MINT-8270176 I2D: score=2 
    SH3GL1Q999612, 3MINT-8270187 I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007049cell cycle IEA--

    SEPT8 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEPT8

    Search CenterWatch for drugs/clinical trials and news about SEPT8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for SEPT8 gene (4 alternative transcripts): 
    NM_001098811.1  NM_001098812.1  NM_001098813.1  NM_015146.1  

    Unigene Cluster for SEPT8:

    Septin 8
    Hs.522057  [show with all ESTs]
    Unigene Representative Sequence: AF179995
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378719(uc003kxr.2) ENST00000481030 ENST00000378721 ENST00000296873(uc003kxs.1 uc003kxu.2 uc011cxi.1 uc003kxv.2)
    ENST00000378706 ENST00000378699 ENST00000378701 ENST00000458488 ENST00000371478
    ENST00000453480 ENST00000414594 ENST00000371493 ENST00000481794 ENST00000492490
    ENST00000448933(uc003kxt.2)

    miRNA
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    8/20 QIAGEN miScript miRNA Assays for microRNAs that regulate SEPT8 (see all 20):
    hsa-miR-30c hsa-miR-520d-5p hsa-miR-30d hsa-miR-183* hsa-miR-30a hsa-miR-4325 hsa-miR-520g hsa-miR-556-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEPT8
    Clone
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEPT8

    Additional mRNA sequence: 

    AF179995.1 AF440761.1 AF440762.1 AF440763.1 AK057797.1 BC001329.1 BC140759.1 BC171779.1 
    D86957.1 

    22 DOTS entries:

    DT.95309873  DT.91955824  DT.445350  DT.110097  DT.91653311  DT.95309869  DT.95309871  DT.99955875 
    DT.120876759  DT.95245773  DT.120876757  DT.120876720  DT.100807333  DT.100807330  DT.100807331  DT.100807332 
    DT.120876724  DT.120876745  DT.120876755  DT.40303743  DT.92443141  DT.120876765 

    1 AceView cDNA sequence:

    AW752481 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT8 (see all 11)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a ·
    SP1:                                -     -     -     -     -                             -                                                                     
    SP2:                                                        -                             -                                                                     
    SP3:                                                        -                             -                                                                 -   
    SP4:                                                        -                             -                                                                 -   
    SP5:                                                                                      -                             -                                       

    ExUns: 13b ^ 14
    SP1:            
    SP2:            
    SP3:  -         
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for SEPT8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEPT8 expression in normal human tissues (normalized intensities)      SEPT8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTCTAAA
    SEPT8 Expression
    About this image


    SEPT8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 5 entries
             Thalamus
             Occipital Lobe   
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Spinal Cord (Nervous System)

    See SEPT8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEPT8

    SOURCE GeneReport for Unigene cluster: Hs.522057

    UniProtKB/Swiss-Prot: SEPT8_HUMAN, Q92599
    Tissue specificity: Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2
    is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and
    putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe,
    temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3
    are expressed at low levels in prostate, testis and ovary

        SABiosciences Custom PCR Arrays for SEPT8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for SEPT8 gene from 5/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sept81 , 5 septin 81, 5 91.67(n)1
    98.36(a)1
      11 (31.96 cM)5
    203621  NM_033144.21  NP_149156.11 
     535192575 
    chicken
    (Gallus gallus)
    Aves SEPT81 septin 8 83.13(n)
    93.01(a)
      416333  XM_414648.3  XP_414648.3 
    lizard
    (Anolis carolinensis)
    Reptilia SEPT86
    septin 8
    91(a)
    1 ↔ 1
    2(127469725-127539026)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.39312 Xenopus laevis transcribed sequence with moderate similarity more 79.11(n)    BX854238.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb22a032 Danio rerio septin, mRNA (cDNA clone IMAGE3816536) 79.79(n)    BC055257.1 


    ENSEMBL Gene Tree for SEPT8 (if available)
    TreeFam Gene Tree for SEPT8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEPT8 gene
    SEPT32  SEPT92  SEPT142  SEPT42  SEPT12  SEPT122  SEPT72  ENSG000002704662  
    SEPT62  SEPT112  SEPT22  SEPT102  SEPT52  
    17 SIMAP similar genes for SEPT8 using alignment to 10 protein entries:     SEPT8_HUMAN (see all proteins):
    SEPT11    DKFZp547B243    SEPT6    SEPT10    DKFZp564M1416    SEPT14
    MAFK    SEPT9    SEPT4    SEPT3    SEPT7    Nbla02942
    DKFZp686F17268    SEPT12    SEPT5    SEPT2    SEPT1

    SEPT8 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/555 SNPs in SEPT8 are shown (see all 555)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs737870611,2
    C,F--132090382(+) CTTGCC/TGTGGG 1 -- int12Minor allele frequency- T:0.07WA 120
    rs1842967011,2
    --132090383(+) TTGCCA/GTGGGG 1 -- int10--------
    rs1504278551,2
    --132090456(+) CTCAAC/TTCAGA 1 -- int10--------
    rs1382930721,2
    --132090638(+) CAGGGC/TAGGGG 1 -- int10--------
    rs121886561,2
    C,F,H--132090828(+) AGAGCC/TGAGCT 1 -- int118Minor allele frequency- T:0.39NA EA NS WA CSA 1070
    rs1891175501,2
    --132091093(+) CCACAC/TTTTCA 1 -- int10--------
    rs725370851,2
    C--132091651(+) GGAAA-/TTYKTTA 3 -- ds5001 int10--------
    rs20671901,2
    C--132096323(-) GTTGC-/CTTT  
            
    CTTTT
    3 -- int1 trp36Minor allele frequency- CTTT:0.36EU NA EA MN CSA 432
    rs117414491,2
    C,H--132105757(+) tgtgtA/Gtatat 4 -- int10--------
    rs1136860921,2
    C,F--132106025(+) AACCAC/TCACGC 3 -- int11Minor allele frequency- T:0.50NA 2

    HapMap Linkage Disequilibrium report for SEPT8 (132086509 - 132142933 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for SEPT8:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv882918CNV Loss21882294
    esv28018CNV Gain19812545
    nsv528687CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608418    OMIM disorders: --

    6 diseases for SEPT8:    About MalaCards
    parkinson's disease    retinitis    tuberculosis    endotheliitis
    prostatitis    neuronitis


    SEPT8 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    1 Novoseek inferred disease relationship for SEPT8 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leukemia 18 1 12023038 (1)

    Genetic Association Database (GAD): SEPT8
    Human Genome Epidemiology (HuGE) Navigator: SEPT8 (2 documents)

    Export disorders for SEPT8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEPT8 gene, integrated from 9 sources (see all 37):
    (articles sorted by number of sources associating them with SEPT8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2, 3 Nagase T....Nomura N. (1996)
    2. Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202). (PubMed id 12909369)1, 2, 9 Blaeser S....Zieger B. (2003)
    3. The novel human platelet septin SEPT8 is an interaction partner of SEPT4. (PubMed id 15116257)1, 2, 9 Blaser S....Zieger B. (2004)
    4. Human septin-septin interaction: CDCrel-1 partners with KIAA0202. (PubMed id 12023038)1, 2, 9 Blaeser S.... Zieger B. (2002)
    5. Association analysis of susceptibility candidate regi on on chromosome 5q31 for tuberculosis. (PubMed id 20485362)1, 4 Ridruechai C....Tokunaga K. (2010)
    6. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Mammalian septins nomenclature. (PubMed id 12475938)1, 2 Macara I.G.... Zieger B. (2002)
    9. KIAA0202, a human septin family member, interacting with hPFTAIRE1. (PubMed id 12098780)1, 2 Yang T.... Chen J.Y. (2002)
    10. Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11. (PubMed id 10704283)1, 2 Wenderfer S.E.... Monaco J.J. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23176 HGNC: 16511 AceView: SEPT8.1 Ensembl:ENSG00000164402 euGenes: HUgn23176
    ECgene: SEPT8 Kegg: 23176 H-InvDB: SEPT8

    (According to HUGE)
    About This Section
    HUGE: KIAA0202

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEPT8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for SEPT8 gene:
    Search GeneIP for patents involving SEPT8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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