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SEPT7 Gene

protein-coding GIFtS: 59

GC07P035807

septin 7
(Previous name: CDC10 cell division cycle 10 homolog (S. cerevisiae) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CDC10)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CDC10 ^², ³, ⁵
CDC3 ^¹, ²
Nbla02942 ^²
SEPT7A ^¹, ²

Descriptions
CDC10 (cell division cycle 10, S. cerevisiae, homolog) ^²
CDC10 cell division cycle 10 homolog ^²
CDC10 cell division cycle 10 homolog (S. cerevisiae) ^¹
CDC10 protein homolog ^³
cell division cycle 10 ^²
septin 7 ^²

External Ids
HGNC: 1717¹
Entrez Gene: 989²
UniProtKB: Q16181³
Ensembl: ENSG00000122545⁷

Search outside databases for aliases for SEPT7 gene

Previous GC identifer: GC07P035615

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for SEPT7:

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces

cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse.

Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast

CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic

membrane and is essential for cytokinesis. Although the exact function of this gene has not yet

been determined, its high similarity to yeast CDC10 and the high conservative nature of eukaryotic

cell cycle machinery suggest a similar role to that of its yeast counterpart. Alternative splicing

results in two transcript variants encoding different isoforms. [provided by RefSeq]

UniProtKB/Swiss-Prot: SEPT7_HUMAN, Q16181

Function: Required for normal progress through mitosis. Involved in cytokinesis. Required for

normal association of CENPE with the kinetochore

Gene Wiki entry for SEPT7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SEPT7 gene

Entrez Gene cytogenetic band: 7p14.3-p14.1 Ensembl cytogenetic band: 7p14.2 HGNC cytogenetic band: 7p14.2

SEPT7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P035807: (about GC identifiers)

Start:	35,807,152 bp from pter
End:	35,911,442 bp from pter
Size:	104,291 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 35,878,676-35,982,948

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: SEPT7_HUMAN, Q16181 (See protein sequence)

Recommended Name: Septin-7

Size: 437 amino acids; 50680 Da

Subunit: Heterohexamer composed of two heterotrimers containing one copy each of SEPT2, SEPT6 and

SEPT7. The asymmetrical heterotrimers associate head-to-head to form a hexameric unit that

assembles into filaments. Interacts directly with CENPE and links CENPE to septin filaments

composed of SEPT2, SEPT6 and SEPT7

Subcellular location: Cytoplasm. Kinetochore. Spindle. Note=Distributed throughout the cytoplasm in

prometaphase cells. Associated with the spindle during metaphase. Associated with the central

spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase

PDB structures from and Proteopedia :

2QAG (3D)

Secondary accessions: Q52M76 Q6NX50

Alternative splicing: 2 isoforms: Q16181-1 Q16181-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001011553.2 NP_001779.3

ENSEMBL proteins:

ENSP00000381992 ENSP00000344868 ENSP00000381993

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (SEPT7)
	Human Recombinant Proteins from Abnova (SEPT7)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/6 Gene Ontology (GO) cellular component terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000777	condensed chromosome kinetochore	IEA	--
GO:0001725	stress fiber	IDA	15485874
GO:0005634	nucleus	IDA	15485874
GO:0005737	cytoplasm	IEA	--
GO:0005819	spindle	IEA	--

About this table

Antibodies for SEPT7:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for SEPT7
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (SEPT7), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SEPT7)
	Novus Biologicals Antibody for SEPT7

Assays for SEPT7:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q16181

ProtoNet protein and cluster: Q16181

2 Blocks protein families:

IPB000038 Cell division/GTP binding protein

IPB008115 Septin 7 signature

UniProtKB/Swiss-Prot: SEPT7_HUMAN, Q16181

Similarity: Belongs to the septin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT7)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001011553

Applied Biosystems Silencer® siRNAs for SEPT7

Sigma-Aldrich siRNA and siRNA Panels for SEPT7

Sigma-Aldrich shRNA for SEPT7

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SEPT7
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001011553
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001011553
untagged cDNA clones in CMV expression vector (see all 4): NM_001011553

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001788

UniProtKB/Swiss-Prot: SEPT7_HUMAN, Q16181

Function: Required for normal progress through mitosis. Involved in cytokinesis. Required for

normal association of CENPE with the kinetochore

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005198	structural molecule activity	TAS	8037772
GO:0005515	protein binding	IPI	15485874 17685441
GO:0005525	GTP binding	TAS	8037772

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SEPT7

5/15 Interacting proteins for SEPT7 (ENSP00000344868³) via UniProtKB, MINT, and/or STRING (see all 15 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SEPT2	ENSP00000353157³	STRING (score=.983)
PIAS2	ENSP00000262161³	STRING (score=.924)
SEPT6	ENSP00000341524³	STRING (score=.91)
SEPT9	ENSP00000329161³	STRING (score=.879)
CDC42EP5	ENSP00000301200³	STRING (score=.871)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000910	cytokinesis	TAS	8037772
GO:0007049	cell cycle	IEA	--
GO:0007067	mitosis	IEA	--
GO:0051291	protein heterooligomerization	IDA	15485874

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SEPT7

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT7)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_001011553

Sigma-Aldrich siRNA and siRNA Panels for SEPT7

Sigma-Aldrich shRNA for SEPT7

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001011553 NM_001788

REFSEQ mRNAs for SEPT7 gene (2 alternative transcripts):

NM_001011553.2 NM_001788.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001011553 NM_001788

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001011553
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001011553
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_001011553

Additional cDNA sequence:

AB073389.1 AB209677.1 AK223225.1 AK223241.1 AK290545.1 AK297883.1 AK298453.1 AK300601.1

AL050392.1 BC022442.1 BC025987.2 BC067264.1 BC093640.1 BC093642.1 BC107718.1 BX571755.1

BX648365.1 CR591983.1 CR593525.1 CR598145.1 CR609589.1 CR623918.1 CR625618.1 DQ232879.1

S72008.1

24/64 DOTS entries (see all 64 ):

DT.308399 DT.100886352 DT.100886331 DT.100886359 DT.101985258 DT.121043736 DT.100886338 DT.86835742

DT.100045052 DT.121043639 DT.121043616 DT.121043705 DT.121043741 DT.100886361 DT.121043642 DT.121043702

DT.121043623 DT.121043758 DT.97818303 DT.91859297 DT.121043646 DT.121043689 DT.121043712 DT.121043614

24/848 AceView cDNA sequences (see all 848 ):

BM874620 AI753264 BE044042 Y08710 AA633339 BM679420 AW675763 BU608300

AI630074 BM706335 BM907533 CR609589 AI569394 AA034280 BP343109 CD557725

CK819046 BF969659 AI862835 AA582550 T16432 BE043954 BE088931 AL044746

highest scoring ESTs for SEPT7:

S72008 AA010112 AA017214 AA028970 AA034512 AA043354 AA089595 AA099199 AA101143 AA121549

Unigene Cluster for SEPT7:

Septin 7

Hs.191346 [show with all ESTs]

Unigene Representative Sequence: AB209677

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT7 (see all 9 )

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	·	2d	^	3	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15
SP1:																																							-
SP2:					-		-		-		-		-		-		-		-
SP3:									-		-				-		-		-
SP4:															-		-		-
SP5:																			-

About this scheme

ECgene alternative splicing isoforms for SEPT7

3 Ensembl transcripts including schematic representations:

ENST00000399034 ENST00000350320 ENST00000399035

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SEPT7 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SEPT7

¹ / ² / ³

4 probe-sets matching SEPT7 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
32175_at²^{, 3}	U95-A	1	0.81	1.00	0.71	1.25	S72008	1.00	1.00	1.00	1
61689_at²^{, 3}	U95-C	1	0.31	1.00	0.84	0.76	AI831470	0.20	0.25	0.23	2
213151_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AU157515	0.80	1.00	0.91	1
213151_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.191346
Expression variation in blood from EXPOLDB for SEPT7

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SEPT7 gene from 5/20 species (see all 20 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SEPT7¹	--	septin 7	96.17(n) 99.48(a)	475284 XM_532516.2 XP_532516.2
chimpanzee (Pan troglodytes)	SEPT7¹	--	septin 7	99.84(n) 99.76(a)	463349 NM_001009103.1 NP_001009103.1
cow (Bos taurus)	SEPT7¹	--	septin 7	96.41(n) 100(a)	408000 NM_001001168.1 NP_001001168.1
rat (Rattus norvegicus)	Sept7¹	--	septin 7	94.11(n) 99.08(a)	64551 NM_022616.1 NP_072138.1
mouse (Mus musculus)	Sept7^{1, 5}	9⁵	septin 7^{1, 5}	95.04(n)¹ 99.08(a)¹	235072¹ NM_009859.3¹ NP_033989.2¹ AF263285⁵ AJ223782⁵ (see all 25)

About this table Species with no ortholog for SEPT7

ENSEMBL Gene Tree for SEPT7

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SEPT7 gene

ENSG00000214765² SEPT2² ENSG00000120555² LOC441601²

Pseudogenes

5 related pseudogenes

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/422 NCBI SNPs in SEPT7 are shown (see all 422 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 81)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs10255293^1,2	A,C,F,H	35911937(+)	`CCCTGA/GAAACT`	2	--	ng3¹		12		EU EA WA NA	1054
--	rs2715597^1,2	A,C,F,H	35911727(-)	`cagtcG/Aagtcg`	2	--	ng3¹		4		EU EA WA	392
--	rs10255066^1,2	A,C	35911709(+)	`agtgcA/Ggtggc`	2	--	ng3¹		0	--	--	--	--
--	rs10260509^1,2	C,F	35805699(+)	`TCAAGA/GTATTT`	2	--	ng5¹		3		NA	140
	rs11977124^1,2	C	35806564(+)	`CACTTC/TTCACC`	2	--	ng5¹		0	--	--	--	--
	rs11973399^1,2	C	35806288(+)	`GGGAAC/TGTTCC`	2	--	ng5¹		0	--	--	--	--
	rs2710801^1,2	A,C,F,H,O	35906831(-)	`CAACAT/CGTCCT`	2	--	int¹		7		NA EU EA WA	554
	rs2727852^1,2	A,C,F,H,O	35853128(-)	`CTGCAT/CGGTCT`	2	--	int¹		11		EU EA WA NA	980
	rs1420642^1,2	A,C,F,H,O	35836911(+)	`AAGGAT/GTATCT`	2	--	int¹		11		NA EA EU	872
--	rs2715604^1,2	A,C,F,H,O	35870905(+)	`GATATG/ATAGGA`	2	--	int¹		7		EU EA WA NA	560

About this table

HapMap Linkage Disequilibrium images for SEPT7 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603151

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/34 PubMed articles for SEPT7 gene (see all 34 ):

Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae. (PubMed id 8037772)^{2, 3, 4} Nakatsuru S.... Nakamura Y. (1994)
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. (PubMed id 18460473)^{3, 4} Zhu M....Yao X. (2008)
Structural insight into filament formation by mammalian septins. (PubMed id 17637674)^{3, 4} Sirajuddin M....Wittinghofer A. (2007)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)^{3, 4} Rush J.... Comb M.J. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Structural analysis of septin 2, 6, and 7 complexes. (PubMed id 16914550)^{1, 3} Low C. and Macara I.G. (2006)
Interaction of the S100A4 (Mts1) protein with septins Sept2, Sept6, and Sept7 in vitro. (PubMed id 14531065)^{1, 3} Koshelev Y.A....Georgiev G.P. (2003)
[Study on the anti-invasion effect of SEPT7 gene for U251MG glioma cell in vitro.] (PubMed id 18543212)³ Xu S....Pu P. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 989	HGNC: 1717	AceView: CDC10	Ensembl:ENSG00000122545	euGenes: HUgn989
ECgene: SEPT7	H-InvDB: SEPT7

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for SEPT7	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SEPT7
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for SEPT7:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SEPT7-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SEPT7		Antibodies for SEPT7
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SEPT7		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
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	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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SEPT7 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for SEPT7

Summaries
for SEPT7

Genomic Location
for SEPT7

Proteins
for SEPT7

Protein Domains/
Families
for SEPT7

Gene Function
for SEPT7

Pathways & Interactions
for SEPT7

Drugs & Compounds
for SEPT7

Transcripts
for SEPT7

Expression
for SEPT7

Orthologs
for SEPT7

Paralogs
for SEPT7

SNPs/Variants
for SEPT7

Disorders & Mutations
for SEPT7

Medical News
for SEPT7

Publications
for SEPT7

Search for SEPT7

Genome Databases showing SEPT7

Other Databases showing SEPT7

Specialized Databases showing SEPT7

Licensable Technologies
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Services
for SEPT7

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SEPT7 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor SEPT7

Summariesfor SEPT7

Genomic Locationfor SEPT7

Proteinsfor SEPT7

Protein Domains/Familiesfor SEPT7

Gene Functionfor SEPT7

Pathways & Interactionsfor SEPT7

Drugs & Compoundsfor SEPT7

Transcriptsfor SEPT7

Expression for SEPT7

Orthologsfor SEPT7

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SNPs/Variantsfor SEPT7

Disorders & Mutationsfor SEPT7

Medical Newsfor SEPT7

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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