SEPT6 Gene
protein-coding GIFtS: 54
GCID: GC0XM118750
|
|
septin 6
| |
Aliases
for SEPT6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Septin 61 2 | | MGC166191 | | SEP21 2 3 5 | | MGC203391 | | KIAA01281 3 5 | | Septin 22 | | SEPT21 2 | | Septin-61 |
Export aliases for SEPT6 gene to outside databasesPrevious GC identifers: GC0XM113567 GC0XM115735 GC0XM116725 GC0XM117503 GC0XM118531 GC0XM118633 GC0XM108243 |
Summaries
for SEPT6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for SEPT6:
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One versionof pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with thebreakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes fourtranscript variants encoding three distinct isoforms. An additional transcript variant has been identified, but itsbiological validity has not been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: SEPT6_HUMAN, Q14141Function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved incytokinesis. May play a role in HCV RNA replication
Gene Wiki entry for SEPT6
|
Genomic Views
for SEPT6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011786.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the SEPT6 gene promoter:
HSF1short HSF1 (long)
Other transcription factors
Search SABiosciences Chromatin IP Primers for SEPT6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEPT6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq24 Ensembl cytogenetic band: Xq24 HGNC cytogenetic band: Xq24SEPT6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM118750: view genomic region
(about GC identifiers)
Start:
|
118,749,687 bp from pter |
End:
|
118,827,333 bp from pter |
Size:
|
77,647 bases |
Orientation:
|
minus strand |
|
Proteins
for SEPT6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: SEPT6_HUMAN, Q14141 (See
protein sequence)Recommended Name: Septin-6 Size: 434 amino acids; 49717 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellularmembranes, actin filaments and microtubules. GTPase activity is required for filament formation. Filaments areassembled from asymmetrical heterotrimers, composed of SEPT2, SEPT6 and SEPT7 that associate head-to-head to form ahexameric unit. Within the trimer, directly interacts with SEPT2 and SEPT7. Also interacts with SEPT9 and SEPT12.Interaction with SEPT12 alters filament structure. Interacts with SOCS7. Interacts with HCV NS5B and with HNRNPA1
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cleavagefurrow. Midbody. Note=In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in closeapposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to themidbody, the ingressing cleavage furrow, and the central spindle
Miscellaneous: Coordinated expression with SEPT2 and SEPT7
1 PDB 3D structure from  and Proteopedia  for SEPT6:2QAG (3D)
Secondary accessions: Q5JTK0 Q969W5 Q96A13 Q96GR1 Q96P86 Q96P87Alternative splicing: 4 isoforms: Q14141-1 Q14141-2 Q14141-3 Q14141-4 Explore the universe of human proteins at neXtProt for SEPT6: NX_Q14141
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14141
SEPT6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_055944.2 NP_665798.1 NP_665799.1 NP_665801.1
ENSEMBL proteins: ENSP00000353278 ENSP00000346169 ENSP00000435818 ENSP00000418715 ENSP00000346397 ENSP00000341524 ENSP00000378108 ENSP00000378115 ENSP00000378114
Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
SEPT6 for ontologies About GeneDecksing
SEPT6 Antibody Products:
Assay Products for SEPT6: |
Protein
Domains /
Families
for SEPT6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
SEPT6 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14141ProtoNet protein and cluster: Q14141 1 Blocks protein family: IPB000038 Cell division/GTP binding protein
UniProtKB/Swiss-Prot: SEPT6_HUMAN, Q14141Similarity: Belongs to the septin family |
Function
for SEPT6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: SEPT6_HUMAN, Q14141Function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved incytokinesis. May play a role in HCV RNA replication
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for SEPT6 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEPT6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEPT6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT6 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
SEPT6 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for SEPT6:
Animal Models:
Mouse knock-out Sept6tm1Nosa for SEPT6
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Sept6):
SEPT6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for SEPT6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for SEPT6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/29 Interacting proteins for SEPT6 (Q141411, 2, 3 ENSP000003415244) via UniProtKB, MINT, STRING, and/or I2D (see all 29)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
SEPT6 for ontologies About GeneDecksing
|
Drugs & Compounds
for SEPT6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for SEPT6
Search CenterWatch for drugs/clinical trials and news about SEPT6
|
Transcripts
for SEPT6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for SEPT6 gene (4 alternative transcripts): NM_015129.5 NM_145799.3 NM_145800.3 NM_145802.3 Unigene Cluster for SEPT6: Septin 6 Hs.496666 [show with all ESTs]Unigene Representative Sequence: NM_14579911 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000360156(uc010nqk.3 uc004ers.3 uc004ert.3) ENST00000354228
ENST00000460411 ENST00000489216(uc004erw.3) ENST00000354416(uc004erv.3)
ENST00000343984 ENST00000467310 ENST00000481072 ENST00000394610(uc004eru.3)
ENST00000394617(uc011mtw.1) ENST00000394616(uc011mtv.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for SEPT6 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for SEPT6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEPT6 |
Additional cDNA sequence: AF397023.1 AF403058.1 AF403059.1 AF403060.1 AF403062.1 AK026589.1 AK091435.1 AK290977.1 AK298487.1 AK299273.1 AK303116.1 AK303224.1 AL833677.1 AY005981.1 AY034177.1 AY679521.1 BC009291.2 BC011922.2 BC036240.1 BC069231.1 D50918.1 22 DOTS entries: DT.100657555 DT.97759960 DT.95326206 DT.100657548 DT.100657544 DT.40118258 DT.452958 DT.121295476 DT.95350254 DT.100039581 DT.100657546 DT.99936998 DT.100657551 DT.95350302 DT.97759963 DT.100865358 DT.121295479 DT.95316375 DT.95350297 DT.100865918 DT.92444932 DT.100657552 24/407 AceView cDNA sequences (see all 407): CA436869 BM991588 AK026589 AF403060 BQ084444 AI026105 AI572866 AF403061 BQ052563 AY679521 BQ941634 AL557244 BM561801 BM827780 BF436025 BQ061868 BM711365 AW294565 N93678 AW167245 BE311818 CR607912 CR610105 AA284400
GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT6 (see all 17) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e | · | 11f | · | 11g | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | · | 15c | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | |
| ExUns: | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | ^ | 18a | · | 18b | ^ | 19a | · | 19b | ^ | 20 | ^ | 21 |
|---|
|
| SP1: | | | - | | - | | | | - | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | | | - | | - | | - | | - | | - | | | | | | |
| SP3: | | | - | | - | | - | | - | | - | | - | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | |
| SP5: | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | |
ECgene alternative splicing isoforms for SEPT6
|
Expression
for SEPT6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| SEPT6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCAATTTTCA
About this image
See SEPT6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for SEPT6
SOURCE GeneReport for Unigene cluster: Hs.496666
UniProtKB/Swiss-Prot: SEPT6_HUMAN, Q14141Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for SEPT6
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEPT6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat SEPT6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEPT6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEPT6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT6 |
Orthologs
for SEPT6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for SEPT6 gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
SEPT61 |
septin 6 |
80.99(n)
94.84(a) |
|
422369 NM_001031125.1 NP_001026296.1 |
lizard
(Anolis carolinensis) |
Reptilia |
SEPT66 |
-- |
91(a) |
1 ↔ 1 |
GL344229.1(10410-26414) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
Str.82052 |
Transcribed sequence with moderate similarity to protein more |
78.71(n) |
|
CF224624.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb77a072 |
Danio rerio septin 6, mRNA (cDNA clone MGC66071 IMAGE6796836), more |
80.15(n) |
|
BC056592.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Sep51 |
CG2916-PA |
63.52(n)
64.52(a) |
|
43990 NM_143704.2 NP_651961.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
unc-616unc-596 |
UNCoordinated family member (unc-59) |
35(a)26(a) |
1 ↔ manypossible ortholog |
V(14731080-14734222) I(13629214-13633485) |
ENSEMBL Gene Tree for SEPT6 (if available)
TreeFam Gene Tree for SEPT6 (if available) |
Paralogs
for SEPT6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for SEPT6 gene
- SEPT32 SEPT92 SEPT142 SEPT42 SEPT12 SEPT72 SEPT122 SEPT7L2
- SEPT112 SEPT22 SEPT102 SEPT82 SEPT52
18 SIMAP similar genes for SEPT6 using alignment to 7 protein entries: SEPT6_HUMAN (see all proteins):SEPT11 DKFZp547B243 SEPT10 SEPT8 DKFZp564M1416 SEPT14
MAFK SEPT9 SEPT3 SEPT7L SEPT7 DKFZp686F17268
Nbla02942 SEPT2 SEPT12 SEPT5 SEPT1 SEPT4
SEPT6 for paralogs About GeneDecksing
|
Genomic Variants
for SEPT6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for SEPT6 (118749687 - 118827333 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for SEPT6
2 CNVs: 83709 96926
Locus Specific Mutation Databases (LSDB): SEPT6
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEPT6 |
|
Disorders
/ Diseases
for SEPT6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 SEPT6 for disorders About MalaCards
SEPT6 for disorders About GeneDecksing
OMIM gene information: 300683
OMIM disorders: --
2 Novoseek disease relationships for SEPT6 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leukemia |
28.9 |
1 |
18492691 (1) |
| tumors |
0 |
1 |
20136629 (1) |
Export disorders for SEPT6 gene to outside databases
|
Publications
for SEPT6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for SEPT6 gene, integrated from 9 sources (see all 46):
(articles sorted by number of sources associating them with SEPT6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)1, 2, 3 Nagase T....Nomura N. (1995)
- Structural analysis of septin 2, 6, and 7 complexes. (PubMed id 16914550)1, 2, 9 Low C. and Macara I.G. (2006)
- SEPT12 interacts with SEPT6 and this interaction alters the filament structure of SEPT6 in Hela cells. (PubMed id 18047794)1, 2 Ding X.... Yu L. (2007)
- Structural insight into filament formation by mammalian septins. (PubMed id 17637674)1, 2 Sirajuddin M.... Wittinghofer A. (2007)
- An RNA-binding protein, hnRNP A1, and a scaffold protein, septin 6, facilitate hepatitis C virus replication. (PubMed id 17229681)1, 2 Kim C.S....Jang S.K. (2007)
- Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. (PubMed id 17803907)1, 2 Kremer B.E.... Macara I.G. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- SEPTIN6, a human homologue to mouse Septin6, is fused to MLL in infant acute myeloid leukemia with complex chromosomal abnormalities involving 11q23 and Xq24. (PubMed id 11809673)1, 2 Ono R.... Hayashi Y. (2002)
|
External Searches for SEPT6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing SEPT6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing SEPT6 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing SEPT6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for SEPT6 gene:
Search GeneIP for patents involving SEPT6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for SEPT6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for SEPT6 | | OriGene shRNA RFP for SEPT6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for SEPT6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for SEPT6 | | | OriGene Protein Over-expression Lysate for SEPT6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for SEPT6 | | OriGene 3'-UTR Clone for SEPT6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for SEPT6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for SEPT6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for SEPT6 | | OriGene Custom Protein Services for SEPT6 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat SEPT6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing SEPT6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEPT6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat SEPT6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat SEPT6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat SEPT6 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for SEPT6 |
| |  |  |  |  | | | | | | Recombinant Protein for SEPT6 |
|
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT6 |
|  |  |  | | | | ThermoFisher Antibodies for SEPT6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat SEPT6 |
|
|
|
|
