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SEPT5 Gene

protein-coding GIFtS: 60

GC22P018077

septin 5
(Previous name: peanut-like 1 (Drosophila) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: PNUTL1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CDCREL ^², ⁵
CDCREL-1 ^²
CDCREL1 ^²
CDCrel-1 ^³
H5 ^¹, ²
HCDCREL-1 ^¹
PNUTL1 ^², ³, ⁵

Descriptions
Cell division control-related protein 1 ^³
Peanut-like protein 1 ^³
cell division control related protein 1 ^²
peanut-like 1 ^²
peanut-like 1 (Drosophila) ^¹
platelet glycoprotein Ib beta chain ^²
septin 5 ^²

External Ids
HGNC: 9164¹
Entrez Gene: 5413²
UniProtKB: Q99719³
Ensembl: ENSG00000184702⁷

Search outside databases for aliases for SEPT5 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for SEPT5:

This gene is a member of the septin gene family of nucleotide binding proteins, originally

described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in

yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of

septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This

gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes.

A translocation involving the MLL gene and this gene has also been reported in patients with acute

myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb,

have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal

(AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal

of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5

kb transcript. An alternatively spliced transcript variant with a different 5' end has also

been identified, but its full-length nature has not been completely determined. [provided by

RefSeq]

UniProtKB/Swiss-Prot: SEPT5_HUMAN, Q99719

Function: Involved in cytokinesis (Potential)

Gene Wiki entry for SEPT5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SEPT5 gene

Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.2

SEPT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P018077: (about GC identifiers)

Start:	18,081,987 bp from pter
End:	18,092,297 bp from pter
Size:	10,311 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000022.9 NT_011519.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: SEPT5_HUMAN, Q99719 (See protein sequence)

Recommended Name: Septin-5

Size: 369 amino acids; 42777 Da

Subunit: May assemble into a multicomponent structure

Secondary accessions: O15251

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002679.2

ENSEMBL proteins:

ENSP00000385356 ENSP00000372515 ENSP00000382384 ENSP00000328190 ENSP00000384535 ENSP00000327409

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (SEPT5)
	Human Recombinant Proteins from Abnova (SEPT5)

OriGene Purified Recombinant Human Protein: SEPT5

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IDA	10321247
GO:0008021	synaptic vesicle	IDA	10321247
GO:0019717	synaptosome	IEA	--
GO:0031105	septin complex	IEA	--

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Antibodies for SEPT5:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of SEPT5
	Sigma-Aldrich Antibodies for SEPT5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (SEPT5), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SEPT5)
	Novus Biologicals Antibodies for SEPT5

Assays for SEPT5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q99719

ProtoNet protein and cluster: Q99719

1 Blocks protein family: IPB000038 Cell division/GTP binding protein

UniProtKB/Swiss-Prot: SEPT5_HUMAN, Q99719

Similarity: Belongs to the septin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SEPT5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002688

Applied Biosystems Silencer® siRNAs for SEPT5

Sigma-Aldrich siRNA for SEPT5

Sigma-Aldrich shRNA for SEPT5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SEPT5
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002688
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002688
untagged cDNA clones in CMV expression vector (see all 2): NM_002688

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002688

UniProtKB/Swiss-Prot: SEPT5_HUMAN, Q99719

Function: Involved in cytokinesis (Potential)

6 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Sept5):

	behavior/neurological	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism
nervous system

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003924	GTPase activity	TAS	9385360
GO:0005198	structural molecule activity	TAS	9611266
GO:0005515	protein binding	IPI	10321247
GO:0005525	GTP binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for SEPT5 (Your Favorite Gene powered by Ingenuity)

Parkinson's Signaling

GeneDecks SEPT5 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for SEPT5

5/15 Interacting proteins for SEPT5 (ENSP00000328190³ Q99719¹) via UniProtKB, MINT, and/or STRING (see all 15 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LSM8	O95777¹	EBI-373345, EBI-347779
SEPT11	Q9NVA2¹	EBI-373345, EBI-957999
SEPT8	Q92599¹	EBI-373345, EBI-958021
PARK2	ENSP00000355865³	STRING (score=.999)
STX1A	ENSP00000222812³	STRING (score=.957)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000910	cytokinesis	TAS	9611266
GO:0007049	cell cycle	IEA	--
GO:0016080	synaptic vesicle targeting	TAS	10321247
GO:0045921	positive regulation of exocytosis	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SEPT5

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SEPT5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002688

Sigma-Aldrich siRNA for SEPT5

Sigma-Aldrich shRNA for SEPT5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002688

REFSEQ mRNAs for SEPT5 gene:

NM_002688.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002688

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002688
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002688
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_002688

Additional cDNA sequence:

AF061154.1 AK056273.1 AK295940.1 BC020397.1 BC025261.1 BC030503.1 CR456545.1 CR597468.1

CR598470.1 CR601109.1 CR603626.1 CR605683.1 CR608884.1 CR608991.1 CR609437.1 CR610263.1

CR613594.1 CR619352.1 CR621875.1 J03259.1 U74628.1 U85431.1 Y11593.1

24/41 DOTS entries (see all 41 ):

DT.217803 DT.97810866 DT.100885289 DT.100885325 DT.100885296 DT.100885290 DT.100885312 DT.100885313

DT.100769098 DT.100885283 DT.100885291 DT.100885318 DT.100698231 DT.120643986 DT.91873438 DT.95183837

DT.95363722 DT.100664732 DT.100885282 DT.100885294 DT.100885305 DT.100885322 DT.120643994 DT.97797509

24/453 AceView cDNA sequences (see all 453 ):

BX428268 BM273082 AI089709 CR605683 T32101 CB153148 CA946742 BP349746

CR610263 AI951935 BM725251 BI792878 BX410920 NM_002688 CK903892 CA411614

AI250779 AI197816 H46034 U74628 BP346614 CB117978 F04630 CR609437

highest scoring ESTs for SEPT5:

AA205074 AA291432 AA339336 AA351247 AA351377 AA351623 AA351737 AA393843 AA401627 AA428871

Unigene Cluster for SEPT5:

Septin 5

Hs.283743 [show with all ESTs]

Unigene Representative Sequence: NM_002688

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT5 (see all 9 )

ExUns:	1	^	2	^	3a	·	3b	·	3c	·	3d	^	4a	·	4b	·	4c	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	·	11c	^	12	^	13a	·	13b	·
SP1:													-		-																						-
SP2:											-		-		-																						-
SP3:													-		-																						-				-
SP4:			-		-		-		-		-		-		-																						-
SP5:					-		-		-		-		-		-

ExUns:	13c	^	14a	·	14b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for SEPT5

6 Ensembl transcripts including schematic representations:

ENST00000406172 ENST00000383045 ENST00000399457 ENST00000330488 ENST00000406395 ENST00000332481

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SEPT5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SEPT5

¹ / ² / ³

7 probe-sets matching SEPT5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34412_s_at²^{, 3}	U95-A	2	1.00	0.50	1.00	1.00	U59632	0.80	0.58	0.70	1
209767_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	AA702163	0.80	0.88	0.84	1
206655_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	NM_000407	0.60	0.83	0.73	1
209768_s_at²^{, 3}	U133-A	2	1.00	0.50	--	--	AI860917	0.80	0.75	0.78	1
209767_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
206655_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
209768_s_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

GeneDecks SEPT5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGCACAATG

SOURCE GeneReport for Unigene cluster: Hs.283743

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SEPT5 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SEPT5¹	--	septin 5	92.23(n) 98.86(a)	486419 XM_543545.2 XP_543545.2
chimpanzee (Pan troglodytes)	SEPT5¹	--	septin 5	99.73(n) 100(a)	458652 XM_001166198.1 XP_001166198.1
cow (Bos taurus)	SEPT5¹	--	septin 5	91.96(n) 98.64(a)	615408 NM_001076371.1 NP_001069839.1
rat (Rattus norvegicus)	Sept5¹	--	septin 5	89.39(n) 98.3(a)	116728 NM_053931.2 NP_446383.2
mouse (Mus musculus)	Sept5^{1, 5}	16 (11.42 cM)⁵	septin 5^{1, 5}	89.52(n)¹ 98.92(a)¹	18951¹ NM_213614.1¹ NP_998779.1¹ AA032529⁵ AF033350⁵ (see all 13)

About this table Species with no ortholog for SEPT5

ENSEMBL Gene Tree for SEPT5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SEPT5 gene

SEPT4² SEPT1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/43 NCBI SNPs in SEPT5 are shown (see all 43 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 42)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1043004^1,2	C,H	18088345(+)	`AGTGTG/AACTCG`	1	N/D	mis¹ ese³		6		MN EU EA WA	766
--	rs2518841^1,2	C	18081884(+)	`GGCCGC/TGGTCT`	1	--	ng5¹		0	--	--	--	--
--	rs2518842^1,2	C	18081887(+)	`CGTGGG/TCTCGG`	1	--	ng5¹		0	--	--	--	--
	rs12165395^1,2	A,F,H	18082781(+)	`CCCCAT/CACACA`	1	--	int¹		4		EU EA WA	418
--	rs9618673^1,2	A	18083773(+)	`GGGTGA/GCCAGT`	1	--	int¹		0	--	--	--	--
	rs2518847^1,2	H	18084896(+)	`GTCCCT/CGGAGT`	1	--	int¹		4		EU EA WA	418
--	rs72448831^1,2	--	18080218(+)	`CATTC-/TTTT TTTTT`	1	--	ng5¹		0	--	--	--	--
--	rs2518844^1,2	--	18081934(+)	`gccgcC/Gctggg`	1	--	ng5¹ tfbs³		0	--	--	--	--
--	rs71317155^1,2	--	18080245(+)	`TTTTT-/TT TTTTTGAGAC`	1	--	ng5¹		0	--	--	--	--
--	rs2733979^1,2	--	18080894(+)	`TCAGAA/GATGGA`	1	--	ng5¹ tfbs³		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for SEPT5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602724

4 Novoseek disease relationships for SEPT5 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
velo-cardio-facial syndrome	73.01	2	10940632 (1)
digeorge syndrome	61.89	2	10940632 (1)
leukemia	0.29	2	16767699 (1)
tumors	0.00	3	16179808 (2), 11167005 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/53 PubMed articles for SEPT5 gene (see all 53 ):

Structure and expression of the human septin gene HCDCREL-1. (PubMed id 9611266)^{2, 3, 4} Yagi M....Ware J. (1998)
A human gene similar to Drosophila melanogaster peanut maps to the DiGeorge syndrome region of 22q11. (PubMed id 9385360)^{2, 3, 4} McKie J.... Scambler P.J. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{3, 4} Collins J.E.... Dunham I. (2004)
Alternative expression of platelet glycoprotein Ib(beta) mRNA from an adjacent 5' gene with an imperfect polyadenylation signal sequence. (PubMed id 9022087)^{3, 4} Zieger B.... Ware J. (1997)
Peanut-like 1 (septin 5) gene expression in normal and neoplastic human endocrine pancreas. (PubMed id 16179808)^{1, 3} Capurso G....Delle Fave G. (2005)
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. (PubMed id 11078524)^{1, 3} Zhang Y.... Dawson T.M. (2000)
The novel human platelet septin SEPT8 is an interaction partner of SEPT4. (PubMed id 15116257)^{1, 3} Blaser S....Zieger B. (2004)
The septin CDCrel-1 binds syntaxin and inhibits exocytosis. (PubMed id 10321247)^{1, 3} Beites C.L....Trimble W.S. (1999)
Septin expression in proliferative retinal membranes. (PubMed id 17625225)^{1, 3} Xin X....Meyer P. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 5413	HGNC: 9164	AceView: GP1BBandPNUTL1	Ensembl:ENSG00000184702	euGenes: HUgn5413
ECgene: SEPT5	H-InvDB: SEPT5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for SEPT5	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SEPT5
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for SEPT5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SEPT5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SEPT5		Antibodies for SEPT5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SEPT5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SEPT5)
	Antibodies (SEPT5)
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	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (SEPT5)
	Antibodies (SEPT5)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for SEPT5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SEPT5

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SEPT5 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for SEPT5

Summaries
for SEPT5

Genomic Location
for SEPT5

Proteins
for SEPT5

Protein Domains/
Families
for SEPT5

Gene Function
for SEPT5

Pathways & Interactions
for SEPT5

Drugs & Compounds
for SEPT5

Transcripts
for SEPT5

Expression
for SEPT5

Orthologs
for SEPT5

Paralogs
for SEPT5

SNPs/Variants
for SEPT5

Disorders & Mutations
for SEPT5

Medical News
for SEPT5

Publications
for SEPT5

Search for SEPT5

Genome Databases showing SEPT5

Other Databases showing SEPT5

Specialized Databases showing SEPT5

Licensable Technologies
for SEPT5

Services
for SEPT5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SEPT5 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor SEPT5

Summariesfor SEPT5

Genomic Locationfor SEPT5

Proteinsfor SEPT5

Protein Domains/Familiesfor SEPT5

Gene Functionfor SEPT5

Pathways & Interactionsfor SEPT5

Drugs & Compoundsfor SEPT5

Transcriptsfor SEPT5

Expression for SEPT5

Orthologsfor SEPT5

Paralogsfor SEPT5

SNPs/Variantsfor SEPT5

Disorders & Mutationsfor SEPT5

Medical Newsfor SEPT5

Publicationsfor SEPT5

Search for SEPT5

Genome Databases showing SEPT5

Other Databases showing SEPT5

Specialized Databases showing SEPT5

Licensable Technologiesfor SEPT5

Servicesfor SEPT5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SEPT5

Summaries
for SEPT5

Genomic Location
for SEPT5

Proteins
for SEPT5

Protein Domains/
Families
for SEPT5

Gene Function
for SEPT5

Pathways & Interactions
for SEPT5

Drugs & Compounds
for SEPT5

Transcripts
for SEPT5

Expression
for SEPT5

Orthologs
for SEPT5

Paralogs
for SEPT5

SNPs/Variants
for SEPT5

Disorders & Mutations
for SEPT5

Medical News
for SEPT5

Publications
for SEPT5

Licensable Technologies
for SEPT5

Services
for SEPT5