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SEPT3 Gene

protein-coding   GIFtS: 52
GCID: GC22P042372

Septin 3


(Previous symbol: SEP3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Septin 31 2
SEP31 2 3 5
bK250D10.32
Neuronal-Specific Septin 32
Neuronal-Specific Septin-32

External Ids:    HGNC: 107501   Entrez Gene: 559642   Ensembl: ENSG000001001677   OMIM: 6083145   UniProtKB: Q9UH033   

Export aliases for SEPT3 gene to outside databases

Previous GC identifers: GC22P038987 GC22P040616 GC22P040697 GC22P025339


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for SEPT3 Gene:
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression
is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not
been determined. Alternative splicing of this gene results in two transcript variants encoding different
isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for SEPT3 Gene:
SEPT3 (septin 3) is a protein-coding gene. Diseases associated with SEPT3 include teratocarcinoma, and temporal lobe epilepsy. GO annotations related to this gene include GTP binding. An important paralog of this gene is SEPT9.

UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)

Gene Wiki entry for SEPT3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NC_018933.2  NT_011520.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the SEPT3 gene promoter:
         USF1   USF2   STAT5A   USF-1:USF-2   C/EBPalpha   Pax-3   USF-1   c-Myb   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for SEPT3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat SEPT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

SEPT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEPT3 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P042372:  view genomic region     (about GC identifiers)

Start:
42,372,276 bp from pter      End:
42,394,225 bp from pter
Size:
21,950 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03 (See protein sequence)
Recommended Name: Neuronal-specific septin-3  
Size: 358 amino acids; 40704 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with
cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By
similarity)
Sequence caution: Sequence=AAG00517.1; Type=Erroneous initiation; Sequence=AAG00518.1; Type=Erroneous initiation;
Sequence=AAG00519.1; Type=Erroneous initiation; Sequence=AAI11780.2; Type=Erroneous initiation;
Sequence=CAD38797.1; Type=Erroneous initiation; Sequence=CAG30458.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for SEPT3:
3SOP (3D)    
Secondary accessions: B1AHR0 Q2NKJ7 Q59GF7 Q6IBZ6 Q8N3P3 Q9HD35
Alternative splicing: 3 isoforms:  Q9UH03-1   Q9UH03-2   Q9UH03-3   

Explore the universe of human proteins at neXtProt for SEPT3: NX_Q9UH03

Explore proteomics data for SEPT3 at MOPED

Post-translational modifications: 

  • Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91 (By similarity)1
  • Ubiquitination2 at Lys226
  • Modification sites at PhosphoSitePlus

  • See SEPT3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_061979.3  NP_663786.2  

    ENSEMBL proteins: 
     ENSP00000391416   ENSP00000379704   ENSP00000383956   ENSP00000379703   ENSP00000379695  
     ENSP00000291236   ENSP00000332866  

    SEPT3 Human Recombinant Protein Products:

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    Novus Biologicals SEPT3 Protein
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    Browse Sino Biological Cell Lysates
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    Browse Proteins at Cloud-Clone Corp.

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    SEPT3 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SEPT: Septins

    4 InterPro protein domains:
     IPR016491 Septin
     IPR000038 Cell_div_GTP-bd
     IPR027417 P-loop_NTPase
     IPR008114 Septin3

    Graphical View of Domain Structure for InterPro Entry Q9UH03

    ProtoNet protein and cluster: Q9UH03

    2 Blocks protein domains:
    IPB000038 Cell division/GTP binding protein
    IPB008114 Septin 3 signature


    UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
    Similarity: Belongs to the septin family


    SEPT3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SEPT3_HUMAN, Q9UH03
    Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)
    Induction: Up-regulated during neuronal differentiation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0003924GTPase activity ----
    GO:0005525GTP binding IEA--
         
    SEPT3 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Sept3):
     nervous system  normal 

    SEPT3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for SEPT3: Sept3tm1Keng Sept3tm1Wtr

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for SEPT3
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for SEPT3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for SEPT3

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SEPT3 (see all 86):
    hsa-miR-642a hsa-miR-1321 hsa-miR-146a hsa-miR-128 hsa-miR-30d hsa-miR-578 hsa-miR-342-3p hsa-miR-30a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat SEPT3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SEPT3_HUMAN, Q9UH03: Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Cell junction, synapse (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    plasma membrane2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030054cell junction IEA--
    GO:0031105septin complex IEA--
    GO:0045202synapse IEA--

    SEPT3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for SEPT3 About    
    See pathways by source

    SuperPathContained pathways About
    1Bacterial invasion of epithelial cells
    Bacterial invasion of epithelial cells

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for SEPT3):
        Bacterial invasion of epithelial cells


    SEPT3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for SEPT3
    Interactions:

        Search GeneGlobe Interaction Network for SEPT3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for SEPT3 (Q9UH032, 3 ENSP000003797044) via UniProtKB, MINT, STRING, and/or I2D (see all 113)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WBP2Q969T92, 3, ENSP000002548064MINT-65566 I2D: score=4 STRING: ENSP00000254806
    MAPK6Q166592, 3MINT-8261912 I2D: score=2 
    PRKG1Q139763, ENSP000003630924I2D: score=1 STRING: ENSP00000363092
    SEPT11Q9NVA23, ENSP000002648934I2D: score=1 STRING: ENSP00000264893
    SEPT6Q141413, ENSP000003415244I2D: score=1 STRING: ENSP00000341524
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis ----
    GO:0007049cell cycle IEA--
    GO:0051301cell division IEA--

    SEPT3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for SEPT3

    2 Novoseek inferred chemical compound relationships for SEPT3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 38.4 1 15200239 (1)
    serine 25.9 1 15107017 (1)



    SEPT3 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for SEPT3 gene (3 alternative transcripts): 
    NM_019106.5  NM_145733.2  NM_145734.1  

    Unigene Cluster for SEPT3:

    Septin 3
    Hs.120483  [show with all ESTs]
    Unigene Representative Sequence: NM_019106
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449288 ENST00000396426(uc003bbr.4) ENST00000406029 ENST00000396425(uc003bbs.4 uc011apj.2)
    ENST00000396417 ENST00000460267 ENST00000291236 ENST00000328414(uc010gys.3)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate SEPT3 (see all 86):
    hsa-miR-642a hsa-miR-1321 hsa-miR-146a hsa-miR-128 hsa-miR-30d hsa-miR-578 hsa-miR-342-3p hsa-miR-30a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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      QuantiFast Probe-based Assays in human, mouse, rat SEPT3

    Additional mRNA sequence: 

    AB209152.1 AF285107.1 AF285108.1 AF285109.1 AK290037.1 AK299919.1 AL833942.1 BC111779.1 
    CR456572.1 

    13 DOTS entries:

    DT.86840677  DT.100683348  DT.100819854  DT.95270345  DT.100819858  DT.120642986  DT.120642993  DT.120643001 
    DT.101965960  DT.120643014  DT.403287  DT.92423021  DT.92423023 

    Selected AceView cDNA sequences (see all 214):

    Z38211 NM_145734 CR456572 D54252 T59361 BM770744 AF285107 BQ924462 
    AI816497 CA388736 AI369698 BQ071318 BU191730 AA666390 BP348363 AW169980 
    BM770133 AF285109 NM_019106 BG315253 AI220013 T33727 BP348877 BM666855 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for SEPT3 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                -                                                                                       
    SP2:                                -                                                                             -         
    SP3:                                -     -     -     -                       -     -                             -         
    SP4:        -     -     -           -                                                                                       
    SP5:                                -                                                                                       


    ECgene alternative splicing isoforms for SEPT3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    SEPT3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATGTTTGCG
    SEPT3 Expression
    About this image


    SEPT3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebellum
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Liver (Hepatobiliary System)
             Mesothelial Cells Hepatic Mesenchyme
    SEPT3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    SEPT3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.120483

    UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
    Tissue specificity: Brain-specific

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SEPT3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Sept31 , 5 septin 31, 5 93.11(n)1
    99.69(a)1
      15 (38.56 cM)5
    240501  NM_011889.21  NP_036019.21 
     822749355 
    chicken
    (Gallus gallus)
    Aves SEPT31 septin 3 84.99(n)
    95.45(a)
      427899  XM_425473.4  XP_425473.4 
    lizard
    (Anolis carolinensis)
    Reptilia SEPT36
    septin 3
    93(a)
    1 ↔ 1
    5(27011389-27033459)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia sept31 septin 3 80.22(n)
    91.1(a)
      100488721  XM_002934722.2  XP_002934768.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sept31 septin 3 74.1(n)
    87(a)
      554123  NM_001024418.1  NP_001019589.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CDC10(YCR002C)4 Component of the septin ring that is required for cytokinesis; more   --   3(118348-117380) 850358  NP_009928.1 


    ENSEMBL Gene Tree for SEPT3 (if available)
    TreeFam Gene Tree for SEPT3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for SEPT3 gene
    SEPT92  SEPT142  SEPT42  SEPT12  SEPT122  SEPT72  ENSG000002704662  SEPT62  
    SEPT112  SEPT22  SEPT102  SEPT82  SEPT52  
    16 SIMAP similar genes for SEPT3 using alignment to 5 protein entries:     SEPT3_HUMAN (see all proteins):
    SEPT9    SEPT12    MAFK    Nbla02942    SEPT4    SEPT2
    DKFZp686F17268    SEPT7    SEPT1    SEPT5    SEPT6    SEPT11
    DKFZp547B243    SEPT10    SEPT14    SEPT8

    SEPT3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for SEPT3 (see all 458)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1400297311,2
    --26287142(+) AAAAA-/GAAAAA 1 -- int10--------
    rs1410296061,2
    C--26287188(+) CCTCCC/TACGTG 1 -- int10--------
    rs113809851,2
    C--26297009(+) TTCCCT/-TTTTT 1 -- int1 trp31Minor allele frequency- -:0.00NA 2
    rs1835183431,2
    --42370931(+) CTAGCA/GCTTTA 2 -- us2k10--------
    rs57511911,2
    C,F,A,H--42370991(+) TGAGAC/TAATGA 2 -- us2k1 tfbs322Minor allele frequency- T:0.50NS EA NA WA 2518
    rs796226961,2
    C,F--42371137(+) GCCTTG/ATATAT 2 -- us2k11Minor allele frequency- A:0.14WA 118
    rs1870357651,2
    --42371194(+) GACATC/TCATTT 2 -- us2k10--------
    rs48204511,2
    C,F--42371333(+) AGTTTC/TTGGGT 2 -- us2k1 tfbs312Minor allele frequency- T:0.24NA WA CSA EA 376
    rs1903735631,2
    --42371499(+) GCAGCA/CCAGCC 2 -- us2k10--------
    rs1821868831,2
    --42371500(+) CAGCCC/TAGCCC 2 -- us2k10--------
    rs1869659661,2
    --42371502(+) GCCCAA/GCCCTG 2 -- us2k10--------
    rs1930820931,2
    --42371609(+) ACTGAC/TTCCTG 2 -- us2k10--------
    rs1147028481,2
    C,F--42371662(+) TTTATT/CAGGTG 2 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1387771631,2
    C--42371679(+) AACCCA/GGGTAT 2 -- us2k10--------
    rs1415194691,2
    --42371681(+) CCCGGA/GTATCC 2 -- us2k10--------
    rs1855275641,2
    --42371688(+) ATCCTC/GTTCTT 2 -- us2k10--------
    rs734170271,2
    C--42371814(+) GGCCAC/TCTCCC 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1887882231,2
    --42371870(+) CCCACA/GTTGAA 2 -- us2k10--------
    rs1113294811,2
    C,F--42371931(+) TTAAAG/ATCCAG 2 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs360887391,2
    F--42371982(+) GCTCTG/ACACAC 2 -- us2k12Minor allele frequency- A:0.50NA 4
    rs1152871651,2
    C,F--42372022(+) ACCAAG/AGACTC 2 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1930561821,2
    --42372050(+) CCACGA/CAGCTC 2 -- us2k10--------
    rs1379101711,2
    --42372340(+) CTGTCC/GATTAG 2 -- us2k10--------
    rs130538331,2
    C,F,H--42372381(+) atgggC/Taaact 2 -- us2k17Minor allele frequency- T:0.02NS NA 682
    rs1439609021,2
    C--42372528(+) ACGGCC/TGCCCG 2 -- us2k10--------
    rs754630691,2
    C,F--42373244(+) GAGACA/TATCTT 2 -- int11Minor allele frequency- T:0.13WA 118
    rs1452910231,2
    C--42373356(+) ACACG-/CACACAC 2 -- int10--------
    rs1481329171,2
    --42373438(+) CCTCCC/GCCGCA 2 -- int10--------
    rs1843936831,2
    C--42373643(+) TTGTGG/TGGGGC 2 -- int10--------
    rs1884924591,2
    --42373644(+) TGTGGG/TGGGCG 2 -- int10--------
    rs7392931,2
    C,F,A,H--42373648(+) GGGGGT/CGGTGG 2 -- int113Minor allele frequency- C:0.27NS EA NA WA CSA 788
    rs1440251041,2
    C--42373967(+) CAGATC/TCCCCT 2 -- int10--------
    rs1473224461,2
    C--42374349(+) GACACA/GGCCCC 2 -- int10--------
    rs1812948141,2
    --42374381(+) TAGTAA/CGTATT 2 -- int10--------
    rs1836213791,2
    --42374416(+) ATTCTC/GTATAA 2 -- int10--------
    rs1896293051,2
    --42374418(+) TCTGTA/TTAACC 2 -- int10--------
    rs1808595411,2
    --42374605(+) CAGCAC/TTGGTT 2 -- int10--------
    rs1410643111,2
    --42374684(+) ACCTTC/GTCTGG 2 -- int10--------
    rs1446179121,2
    --42374695(+) GGTACA/GTAAGT 2 -- int10--------
    rs1508132741,2
    --42374703(+) AGTGTA/CCTTGG 2 -- int10--------
    rs3737827931,2
    C--42374897(+) ATGCT-/GGAGGAGG 2 -- int1 cds10--------
    rs711848521,2
    C--42374935(+) GGAGG-/AGG/  
      AGGAGG
    GACCA
    4 -- cds11NA 2
    rs1392612921,2
    --42374984(+) GTGGCA/GCAGTG 2 -- int10--------
    rs1180611371,2
    C,F--42374985(+) TGGCAC/TAGTGA 2 -- int11Minor allele frequency- T:0.04NA 120
    rs738858791,2
    C,F--42375112(+) CAGTGG/CGTGCT 2 -- int12Minor allele frequency- C:0.10WA 120
    rs8805781,2
    C,F--42375116(-) TATGAG/ACACCC 2 -- int14Minor allele frequency- A:0.08NA WA CSA 124
    rs1500015301,2
    --42375174(+) GTAGTA/GGGCCT 2 -- int10--------
    rs1452690201,2
    --42375204(+) GCTTGC/GGGATC 2 -- int10--------
    rs7632601,2
    C,F,A,H--42375228(+) TCTCCG/ATCAGG 2 -- int114Minor allele frequency- A:0.22NA EA WA CSA 603
    rs1458777221,2
    C--42375591(+) CTGCT-/GAGAGTC 2 -- int10--------
    rs57585271,2
    C,F,A,H--42375761(+) CCCATG/TGGGAG 2 -- int111Minor allele frequency- T:0.47NS EA NA WA 784
    rs121663011,2
    C,F,A,H--42375777(+) GTCTTA/GCCAGT 2 -- int15Minor allele frequency- G:0.01NS EA CSA 420
    rs734170331,2
    C,F--42375852(+) GGGAAT/CACTTC 2 -- int13Minor allele frequency- C:0.18WA CSA 122
    rs1872539251,2
    --42375868(+) CCTCTC/GCCTCC 2 -- int10--------
    rs1178071961,2
    F--42375871(+) CTCCCT/ACCCGC 2 -- int11Minor allele frequency- A:0.01EA 120
    rs1920075451,2
    --42375955(+) TAGAAC/TGGCAG 2 -- int10--------
    rs1815415031,2
    --42375969(+) TGGAAA/GGTGTC 2 -- int10--------
    rs1861973481,2
    --42376209(+) ACGATC/TTCGGC 2 -- int10--------
    rs583527061,2
    C,F--42376278(+) CTAGGC/ATTACA 2 -- int11Minor allele frequency- A:0.50WA 2
    rs1467553491,2
    C--42376286(+) ACAGGC/TGCCTG 2 -- int10--------
    rs57585291,2
    C--42376614(+) CCAATC/TGTATG 2 -- int112Minor allele frequency- T:0.06NA WA CSA EA 374
    rs60025671,2
    C,H--42376679(+) GATAAG/AGAAAC 2 -- int14Minor allele frequency- A:0.00NS EA 418
    rs1902274601,2
    C--42376868(+) CTCCCC/TACTGG 2 -- int10--------
    rs1160403031,2
    C,F--42376923(+) TCAGGT/CACAGA 2 -- int11Minor allele frequency- C:0.13WA 118
    rs48220771,2
    C,H--42376964(+) CAGAGA/GGGACA 2 -- int113Minor allele frequency- G:0.12NA WA CSA EA 375
    rs1828168121,2
    --42377161(+) ACCAGC/TGGTTC 2 -- int10--------
    rs1880168881,2
    --42377184(+) ATGGTG/TCTTCC 2 -- int10--------
    rs96234861,2
    H--42377226(+) TTGGGT/CTGTCA 2 -- int14Minor allele frequency- C:0.00NS EA 420
    rs1115969661,2
    C--42377237(+) CAGCCT/-GGGGG 2 -- int11Minor allele frequency- -:0.50CSA 2
    rs788840641,2
    C--42377270(+) CTAATC/TATCCT 2 -- int10--------
    rs1140953891,2
    C,F--42377315(+) CAAATG/ATCATT 2 -- int11Minor allele frequency- A:0.03WA 118
    rs568610421,2
    C,F--42377399(+) TGCCCA/CGCAAC 2 -- int13Minor allele frequency- C:0.17WA CSA 122
    rs2005800401,2
    --42377667(+) CAGGAA/CGGACG 4 K T mis10--------
    rs1908509001,2
    C--42377668(+) AGGACA/GGACGC 4 T syn10--------
    rs1826590711,2
    C--42377672(+) CGGACA/GCAGCC 4 T A mis10--------
    rs1400943861,2
    C,F--42377715(+) GCCAGC/TGGTGC 4 A V mis12Minor allele frequency- T:0.00NA EU 5801
    rs1998865081,2
    --42377836(+) ATGGTC/GGTTGG 4 V syn10--------
    rs1403702591,2
    C--42377844(+) TGGTAC/TGGAAG 2 -- int10--------
    rs1889248701,2
    C--42377851(+) GAAGGC/TTGTGG 2 -- int10--------
    rs2020853231,2
    --42377877(+) GGTGGC/TGGGCA 2 -- int10--------
    rs22696651,2
    C,F,H--42377878(+) GTGGCG/AGGCAG 2 -- int114Minor allele frequency- A:0.27EA NS NA 3418
    rs119142001,2
    C,F,H--42378070(+) AGCTCG/AGTGTA 2 -- int110Minor allele frequency- A:0.23NS EA NA WA 694
    rs610249731,2
    C,F--42378076(+) GTGTAC/TACAGG 2 -- int14Minor allele frequency- T:0.18WA CSA 124
    rs776946821,2
    C,F--42378085(+) GGCAGC/ACCCTT 2 -- int11Minor allele frequency- A:0.01WA 118
    rs1931363081,2
    --42378087(+) CAGCCC/TCTTCA 2 -- int10--------
    rs1842689851,2
    C--42378112(+) CTTTTA/GGGTTT 2 -- int10--------
    rs1436083271,2
    C--42378188(+) GGTGGA/TCTTAT 2 -- int10--------
    rs773500861,2
    F--42378189(+) GTGGTC/GTTATT 2 -- int11Minor allele frequency- G:0.01NA 120
    rs123301251,2
    C--42378250(+) gctcaC/Tacctg 2 -- int10--------
    rs1130434771,2
    C,F--42378310(+) GAGTTC/TGAGAC 2 -- int12Minor allele frequency- T:0.50WA CSA 4
    rs1875352181,2
    --42378437(+) AACCCA/GGGAGG 2 -- int10--------
    rs1134249851,2
    C,F--42378467(+) AGATCG/ACGCCA 2 -- int12Minor allele frequency- A:0.50WA CSA 4
    rs622410001,2
    C,F--42378507(+) AACTCT/CGCCTC 2 -- int14Minor allele frequency- C:0.38NA WA 8
    rs1439870651,2
    --42378586(+) ACTGCA/GTCACA 2 -- int10--------
    rs1916545911,2
    --42378659(+) AGGCCA/GAGGTG 2 -- int10--------
    rs1838438651,2
    --42378672(+) TGGATC/TACCTG 2 -- int10--------
    rs96200021,2
    C--42378819(+) gaaccC/Tgggag 2 -- int10--------
    rs96234871,2
    A--42378906(+) aaaaaA/Gaagaa 2 -- int1 trp30--------
    rs1807250661,2
    --42378930(+) GGAAGA/GGACCT 2 -- int10--------
    rs1392498611,2
    --42378937(+) ACCTTG/TGCCCC 2 -- int10--------
    rs1844810541,2
    --42379055(+) TCATAC/TGTATC 2 -- int10--------
    rs1905401381,2
    --42379132(+) TTGCCA/GTGGCC 2 -- int10--------
    rs1172681101,2
    F--42379150(+) TCTGTG/ACTGTC 2 -- int11Minor allele frequency- A:0.01EA 120
    rs1820781181,2
    --42379287(+) TCTCCC/TGAGGC 2 -- int10--------
    rs734170381,2
    C,F--42379377(+) GCACCA/CACCCT 2 -- int14Minor allele frequency- C:0.20WA CSA 124
    rs1860531071,2
    --42379456(+) CAAAAC/TTTATC 2 -- int10--------
    rs1494208381,2
    --42379681(+) AACTCA/CTGACT 2 -- int10--------
    rs1904779321,2
    --42379705(+) CCTTCC/TGGTTT 2 -- int10--------
    rs57511941,2
    C,F,A,H--42379813(+) tttcaT/Cagtgg 2 -- int127Minor allele frequency- C:0.22NS EA NA WA CSA 2488
    rs1816103501,2
    --42379815(+) TCACAA/GTGGTT 2 -- int10--------
    rs1448507151,2
    C--42379832(+) ACATAC/TTATAA 2 -- int10--------
    rs57511951,2
    C,F,A,H--42380001(+) ggcaaC/Atccaa 2 -- int112Minor allele frequency- A:0.45NA WA EA 494
    rs588090151,2
    C--42380279(+) CTAGG-/AGGCCCTT 2 -- cds10--------
    rs1428281831,2
    C--42380323(+) ATCACA/GAGAAT 2 -- int10--------
    rs1506382471,2
    C--42380464(+) ATGCCC/GAGGCT 2 -- int10--------
    rs1864055881,2
    --42380491(+) TCTTTC/TTTGTG 2 -- int10--------
    rs1912521781,2
    C--42380608(+) GATCCC/TGGCTC 2 -- int10--------
    rs1827728271,2
    --42380610(+) TCCCGA/GCTCAC 2 -- int10--------
    rs57585311,2
    C,H--42380648(+) gatccT/Gcagcc 2 -- int111Minor allele frequency- G:0.01NA WA CSA EA 256
    rs1860736021,2
    --42380694(+) TGCCCA/GGCTAA 2 -- int10--------
    rs1908860171,2
    C--42381016(+) CACGCC/TGGGCT 2 -- int10--------
    rs1834339871,2
    --42381024(+) GCTAAG/TTTTTT 2 -- int10--------
    rs1878029951,2
    C--42381061(+) TCACCA/GTGTTA 2 -- int10--------
    rs573187161,2
    C,F--42381114(+) GTCTCG/AGCCTC 2 -- int12Minor allele frequency- A:0.50WA CSA 4
    rs123300011,2
    C--42381157(+) gcAAAC/TGGCCT 2 -- int10--------
    rs1125727931,2
    C,F--42381375(+) TAAAAG/ACCACT 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs57585321,2
    C,F,H--42381427(+) GGGTTC/TGAGTT 2 -- int115Minor allele frequency- T:0.01NS EA NA WA CSA 656
    rs121674351,2
    H--42381452(+) TATTAG/ATTATG 2 -- int14Minor allele frequency- A:0.00NS EA 412
    rs1919585761,2
    --42381465(+) GCTCTG/TCACAT 2 -- int10--------
    rs1451226011,2
    --42381479(+) TTGTTA/GGAAGA 2 -- int10--------
    rs1490296011,2
    C--42381558(+) ATATAA/CAAATG 2 -- int10--------
    rs1430496981,2
    --42381591(+) GTACAA/GTATGC 2 -- int10--------
    rs1834855791,2
    C--42381631(+) ATTCTA/GTTTTT 2 -- int10--------
    rs1122044021,2
    C--42381703(+) AACCAC/TGACAC 2 -- int12Minor allele frequency- T:0.06NA 122
    rs7392941,2
    C,F,A--42381726(+) GAGGTT/CGTCCC 2 -- int113Minor allele frequency- C:0.34EA NA 628
    rs1881942751,2
    --42381751(+) CTGTGG/TCTCTG 2 -- int10--------
    rs561775031,2
    C,F--42381892(+) GCCTGG/AATCAT 2 -- int11Minor allele frequency- A:0.05NA 120
    rs1927565561,2
    --42381907(+) CTAGAA/CTTCTG 2 -- int10--------
    rs1387228841,2
    C--42381976(+) CTCCTG/TCTTTG 2 -- int10--------
    rs1844559531,2
    --42382028(+) ACGCTC/TTTCAA 4 L syn10--------
    rs1180162251,2
    C--42382109(+) GCTATC/TGGGCA 4 I syn11Minor allele frequency- T:0.01EA 120
    rs2009832561,2
    --42382126(+) GGACCA/GGGCAG 2 -- int10--------
    rs1893301451,2
    --42382175(+) GAAAGA/GGGAAA 2 -- int10--------
    rs1177368951,2
    C,F--42382352(+) ATTTAG/CACAGG 2 -- int11Minor allele frequency- C:0.15EA 120
    rs1914649801,2
    --42382358(+) ACAGGC/TAGAAA 2 -- int10--------
    rs1411837631,2
    --42382372(+) GTAAGA/GAGTGG 2 -- int10--------
    rs1181428681,2
    F--42382437(+) AGGATC/TGCTTG 2 -- int11Minor allele frequency- T:0.05NA 120
    rs1469607581,2
    C--42382526(+) TGAGAC/TGGAGT 2 -- int10--------
    rs1847332161,2
    --42382573(+) ATCTCA/GGCTCA 2 -- int10--------
    rs1332921,2
    C,F--42382748(+) GATCCG/ACCTGC 2 -- int14Minor allele frequency- A:0.50NA 8
    rs1332931,2
    C,F--42382797(+) ACCACA/GCCCGG 2 -- int17Minor allele frequency- G:0.49NA WA EA 366
    rs1332941,2
    C,F--42382805(+) CGGCCC/TGAAAC 2 -- int16Minor allele frequency- T:0.45NA WA EA 364
    rs772631931,2
    C,F--42383244(+) CTGACC/TGTCAT 4 T syn11Minor allele frequency- T:0.00NA 4550
    rs2002574671,2
    C--42383245(+) TGACCA/GTCATC 4 I V mis10--------
    rs765029291,2
    C--42383275(+) ACCAAA/TTCAAC 4 I F mis10--------
    rs1895539091,2
    C--42383304(+) TCTGCC/TTCTGA 2 -- int10--------
    rs1383491591,2
    C--42383321(+) TGCCCC/TAAAGA 2 -- int10--------
    rs1495614181,2
    --42383446(+) CCCTGC/GTAACT 2 -- int10--------
    rs1814944421,2
    --42383472(+) CCATCC/GGTGCG 2 -- int10--------
    rs1460459941,2
    --42383476(+) CGGTGC/TGGGGG 2 -- int10--------
    rs1869214241,2
    --42383495(+) GAATCC/TGGCAG 2 -- int10--------
    rs96200031,2
    C--42383506(+) CAGGTA/GTCCTA 2 -- int10--------
    rs591896061,2
    C,F--42383583(+) CTAGGT/CCTTGT 2 -- int13Minor allele frequency- C:0.02WA EU 1443
    rs1897631381,2
    --42383827(+) ATCTGC/GATTGG 2 -- int10--------
    rs1814634881,2
    --42383946(+) TCCACA/GAGGAA 2 -- int10--------
    rs582734241,2
    C,F--42383954(+) GAAGTT/CTGACT 2 -- int13Minor allele frequency- C:0.18WA CSA 122
    rs592680481,2
    C,F--42384017(+) TGGTGT/CCCCAG 2 -- int13Minor allele frequency- C:0.19WA CSA 122
    rs1860555941,2
    --42384018(+) GGTGTA/CCCAGC 2 -- int10--------
    rs1176441341,2
    C,F--42384019(+) GTGTCC/TCAGCA 2 -- int11Minor allele frequency- T:0.01NA 120
    rs598919371,2
    C,F--42384048(+) AGCAAA/GGAGGA 2 -- int14Minor allele frequency- G:0.21WA CSA 124
    rs622410031,2
    C,F--42384077(+) AGGGCA/GCTTCA 2 -- int11Minor allele frequency- G:0.01NA 120
    rs1332951,2
    C,F,A,H--42384125(+) GTCGGG/AGGGAG 2 -- int126Minor allele frequency- A:0.12NS EA NA WA CSA 2522
    rs758417771,2
    F--42384159(+) AGTGCA/TGGGCT 2 -- int11Minor allele frequency- T:0.03WA 118
    rs110900651,2
    C,F,A,H--42384171(+) CTGGAT/CTGGGG 2 -- int16Minor allele frequency- C:0.26NA WA 246
    rs1179694681,2
    F--42384172(+) TGGATT/GGGGGC 2 -- int11Minor allele frequency- G:0.04NA 120
    rs570214291,2
    C,F--42384193(+) AGGGTA/GGGGAC 2 -- int13Minor allele frequency- G:0.18WA CSA 122
    rs1895640311,2
    --42384282(+) AAGTAC/TTATCT 2 -- int10--------
    rs671322431,2
    C--42384437(+) GGGGG-/GTCCCA 2 -- int10--------
    rs1463397541,2
    --42384494(+) GGATGA/GCACAA 2 -- int10--------
    rs72875281,2
    C,F,A--42384511(+) TAAGCC/TCCAAA 2 -- int11Minor allele frequency- T:0.11WA 118
    rs1392834131,2
    C--42384541(+) TGATGA/GTAGGG 2 -- int10--------
    rs1171059491,2
    F--42384626(+) GGCTTC/TGACCC 2 -- int11Minor allele frequency- T:0.01EA 120
    rs1822228321,2
    --42384627(+) GCTTCA/GACCCC 2 -- int10--------
    rs731651801,2
    --42384649(+) GAACCA/GTCAGA 2 -- int10--------
    rs57585341,2
    A--42384797(+) GGGGGC/TTAGGA 2 -- int10--------
    rs1861112281,2
    --42384858(+) GGCACA/GGTGGC 2 -- int10--------
    rs1910139101,2
    --42384895(+) GAAGCC/TGAGGC 2 -- int10--------
    rs1835721341,2
    --42385041(+) GGGAGA/GATTGC 2 -- int10--------
    rs1426359501,2
    --42385077(+) GTGAGC/TCAATG 2 -- int10--------
    rs48220781,2
    --42385118(+) aaagtA/Gagacc 2 -- int10--------
    rs711848541,2
    C--42385130(+) AAAAAA/-AAAAA 2 -- int11Minor allele frequency- -:0.00NA 2
    rs1332961,2
    C,F--42385261(+) AGACAA/GTAGTC 2 -- int116Minor allele frequency- G:0.06MN NA WA CSA EA 743
    rs1928914551,2
    --42385311(+) AAGATA/GTCCTG 2 -- int10--------
    rs1828029121,2
    --42385338(+) GGGGCA/TTAAAG 2 -- int10--------
    rs48204541,2
    C,F,A--42385352(+) GGCAGG/AATCTG 2 -- int114Minor allele frequency- A:0.20EA NA WA CSA 554
    rs1175825651,2
    C,F--42385399(+) CTGCTC/TTACAG 2 -- int11Minor allele frequency- T:0.03NA 120
    rs622410231,2
    C,F--42385429(+) GTGTCG/AGAGAC 2 -- int18Minor allele frequency- A:0.19NA WA CSA 250
    rs1871831701,2
    --42385440(+) GAGAGA/GTAGCA 2 -- int10--------
    rs799068031,2
    C--42385696(+) GAGAAG/TGCCCC 2 -- int10--------
    rs2004002771,2
    C--42385700(+) AGGCCC/GCCTGT 2 -- int11Minor allele frequency- G:0.00EU 1323
    rs2020244521,2
    C--42385701(+) GGCCCC/GCTGTC 2 -- int11Minor allele frequency- G:0.00EU 1323
    rs734170561,2
    C,F--42385720(+) CTGTTC/TCCATC 2 -- int15Minor allele frequency- T:0.03WA CSA EU 1447
    rs2017318171,2
    --42385731(+) CCCTCC/TTTTCT 2 -- int10--------
    rs65193011,2
    C,F,A,H--42385967(+) ACATAG/AGAAAT 2 -- int129Minor allele frequency- A:0.50NS EA NA WA 3082
    rs1913149601,2
    --42386036(+) CTAGTA/CCTCAC 2 -- int10--------
    rs1332971,2
    C,A,H--42386057(+) tctttT/Gttttt 2 -- int13Minor allele frequency- G:0.17NA WA 6
    rs3732042161,2
    C--42386057(+) TCTTT-/GTTTTT 2 -- int10--------
    rs96200041,2
    C,F--42386084(+) ctgtcG/Ccccag 2 -- int11Minor allele frequency- C:0.00NA 2
    rs1396660881,2
    C--42386090(+) CCCAGC/GCTGGA 2 -- int10--------
    rs96200051,2
    C,F--42386130(+) agctcC/Tgcctt 2 -- int11Minor allele frequency- T:0.00NA 2
    rs1926092901,2
    --42386146(+) TTCACA/GCCATT 2 -- int10--------
    rs588746471,2
    C,F--42386269(+) GGTCTC/TGGCTA 2 -- int17Minor allele frequency- T:0.15NA WA EA 366
    rs1497469161,2
    C--42386375(+) TTCTAC/TAAGCT 2 -- int10--------
    rs1852801481,2
    --42386475(+) TTGGGC/TGTGGT 2 -- int10--------
    rs1477618121,2
    --42386476(+) TGGGCA/GTGGTG 2 -- int10--------
    rs1128151361,2
    C,F--42386477(+) GGGCGC/TGGTGG 2 -- int11Minor allele frequency- T:0.50NA 2
    rs1469511001,2
    C--42386487(+) GCTCAC/TGCCTG 2 -- int10--------
    rs1475971801,2
    --42386494(+) CCTGTA/GATCCC 2 -- int10--------
    rs1481409431,2
    --42386534(+) CACGAA/GGTCAG 2 -- int10--------
    rs59960981,2
    --42386546(+) agatcA/Gagacc 2 -- int10--------
    rs1901603821,2
    --42386612(+) GGGTGC/TGGTGG 2 -- int10--------
    rs1451711151,2
    C--42386684(+) GGCGGC/TGCTTG 2 -- int10--------
    rs1112263101,2
    C,F--42386781(+) ACTTAC/AAATTG 2 -- int12Minor allele frequency- A:0.16WA 120
    rs1387980601,2
    --42386838(+) CAAGGC/TGGGTG 2 -- int10--------
    rs1332981,2
    C,F,A,H--42386949(+) TGTAAT/GCCCAG 2 -- int17Minor allele frequency- G:0.07NA WA CSA 14
    rs2019244761,2
    --42387113(+) AATAG-/AAAAAT 2 -- int10--------
    rs665808061,2
    C--42387116(+) AGAAA-/CATGAA 2 -- int10--------
    rs802723831,2
    C--42387116(+) TAGAAA/CATGAA 2 -- int10--------
    rs1820234031,2
    --42387232(+) GAATAC/TAACAT 2 -- int10--------
    rs1463288921,2
    C--42387260(+) CCCCAC/GTGGGC 2 -- int10--------
    rs121653731,2
    C--42387310(+) CTGAGA/TTGAGC 2 -- int10--------
    rs734170621,2
    C,F--42387391(+) TAATTG/ATATAG 2 -- int13Minor allele frequency- A:0.20WA CSA 122
    rs1845729141,2
    C--42387568(+) CTCCTC/TGCCTC 2 -- int10--------
    rs1495098061,2
    C,F--42387596(+) TGAAGT/CAAATG 4 /A /V mis11Minor allele frequency- C:0.00NA 4552
    rs351695951,2
    C,F--42387654(+) AAGACG/AGAGAA 4 /T syn13Minor allele frequency- A:0.03NA WA 4746
    rs1439931521,2
    C--42387681(+) GGTGCC/TTGGGG 2 -- int10--------
    rs2008040681,2
    --42387705(+) CTGATA/GCCCCC 2 -- int10--------
    rs1166718951,2
    F--42387739(+) GTGCAC/TGTCCT 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1486675791,2
    --42387865(+) CTGTAC/TCCAGA 2 -- int10--------
    rs117030911,2
    H--42387869(+) ACCCAG/AAAAGC 2 -- int14Minor allele frequency- A:0.00NS EA 404
    rs774809611,2
    C--42388018(+) CTGCCG/TTAGTT 2 -- int10--------
    rs1885955761,2
    --42388052(+) TAGACC/TGAGTG 2 -- int10--------
    rs1146346491,2
    F--42388071(+) GCTTCC/TCCCGC 2 -- int11Minor allele frequency- T:0.02WA 118
    rs57585361,2
    C,F,A,H--42388075(+) CCCCCC/GCTAGA 2 -- int114Minor allele frequency- G:0.20NS EA NA WA CSA 662
    rs1113425551,2
    C,F--42388136(+) CCAGCA/CCTTTG 2 -- int13Minor allele frequency- C:0.22WA CSA 122
    rs1142321161,2
    C,F--42388212(+) AACTTA/GTCTCT 2 -- int11Minor allele frequency- G:0.05WA 118
    rs1807745761,2
    --42388236(+) AAATTA/GGCCAG 2 -- int10--------
    rs1478569711,2
    --42388251(+) GGTGGC/TGCATG 2 -- int10--------
    rs1120608001,2
    C,F--42388272(+) CAGCTG/ACTCGG 2 -- int11Minor allele frequency- A:0.50WA 2
    rs1851771961,2
    --42388276(+) TACTCA/GGGAGG 2 -- int10--------
    rs734170701,2
    C,F--42388396(+) AAGTAC/TAAAGC 2 -- int13Minor allele frequency- T:0.22WA CSA 122
    rs1908720791,2
    --42388419(+) AAGGAA/GAGCTG 2 -- int10--------
    rs1450675811,2
    --42388474(+) ACCCAA/GGACTC 2 -- int10--------
    rs1822936381,2
    --42388504(+) TCTTTC/TCAAGA 2 -- int10--------
    rs1874266391,2
    --42388583(+) GAGGAC/TCATAT 2 -- int10--------
    rs1475876601,2
    --42388584(+) AGGACC/TATATG 2 -- int10--------
    rs1913917491,2
    C--42388638(+) CACATA/GTGTCT 2 -- int10--------
    rs96116971,2
    C,H--42388670(+) CAGCAA/C/GGAGAG 6 Q H syn1 mis15NS EA NA 422
    rs1998688841,2
    --42388675(+) GGAGAG/TCATGC 4 S I mis10--------
    rs562346241,2
    C,F--42388826(+) CATTTA/GTTAAG 2 -- int18Minor allele frequency- G:0.23WA NA CSA EA 368
    rs1332991,2
    C,F,A,H--42388841(+) TATAGA/GTCAAG 2 -- int126Minor allele frequency- G:0.19NS EA NA WA CSA 2530
    rs734170741,2
    C,F--42388852(+) GCACTG/ATCTCA 2 -- int13Minor allele frequency- A:0.22WA CSA 122
    rs557132101,2
    F--42388922(+) GAAGAC/TGATGC 2 -- int10--------
    rs1837588521,2
    --42388939(+) GCAGGA/GGTAAC 2 -- int10--------
    rs1870449511,2
    --42389261(+) AGCACC/TGGAAG 2 -- int10--------
    rs1136765761,2
    C--42389332(+) TTTTTT/-GAGAC 2 -- int11Minor allele frequency- -:0.50CSA 2
    rs1501166431,2
    --42389389(+) AGTGGC/TGCAAT 2 -- int10--------
    rs20975611,2
    C,F,A--42389431(+) TCAAGT/CAATTC 2 -- int13Minor allele frequency- C:0.31NA WA 124
    rs20975621,2
    C,F,A,H--42389500(+) TTTTAT/CTTATC 2 -- int19Minor allele frequency- C:0.26NS EA WA NA 660
    rs1453116471,2
    --42389653(+) CCATGC/TCTGGT 2 -- int10--------
    rs7392951,2
    C,F,A,H--42389698(+) TCACTA/GTGTTA 2 -- int110Minor allele frequency- G:0.23EA NA WA CSA 294
    rs1903833391,2
    --42389835(+) GCTTGG/TCCAAT 2 -- int10--------
    rs1333001,2
    C,F,A,H--42389839(+) GGCCAA/GTGATT 2 -- int112Minor allele frequency- G:0.47NS EA NA WA 788
    rs1821933741,2
    --42389888(+) TGTCAG/TGTAGT 2 -- int10--------
    rs1869752341,2
    --42389944(+) CTTCCA/GACCGG 2 -- int10--------
    rs7392961,2
    C,F,O,A,H--42389948(+) CAACCG/AGATTA 2 -- int130Minor allele frequency- A:0.24NA EA NS WA 3148
    rs560528201,2
    C,F--42390024(+) TTCTCT/CTCTAT 2 -- int12Minor allele frequency- C:0.10WA 120
    rs1932458251,2
    --42390073(+) CACAGC/TGTCTA 2 -- int10--------
    rs1854097651,2
    --42390074(+) ACAGCG/TTCTAG 2 -- int10--------
    rs1333011,2
    C,F,A,H--42390093(+) CGTGCT/CCATTG 2 -- int114Minor allele frequency- C:0.47NS EA NA WA CSA 792
    rs1451516401,2
    --42390095(+) TGCCCA/GTTGTA 2 -- int10--------
    rs72909071,2
    C,F,A,H--42390209(+) CCTCCG/ATGACC 2 -- int119Minor allele frequency- A:0.26NS EA WA NA CSA 2226
    rs72906551,2
    C,F,A,H--42390225(+) AGAAGC/GTCACC 2 -- int114Minor allele frequency- G:0.26NA NS EA WA CSA 810
    rs1890781241,2
    C--42390393(+) TATTTC/GGGGTC 2 -- int10--------
    rs1928531951,2
    --42390406(+) GGTCTA/GTCTGT 2 -- int10--------
    rs1844469531,2
    --42390449(+) TGACAA/GAGCTT 2 -- int10--------
    rs21575891,2
    H--42390566(+) GTGTCA/GCCGCC 2 -- int14Minor allele frequency- G:0.00NS EA 420
    rs1390350311,2
    --42390568(+) GTCACC/TGCCTC 2 -- int10--------
    rs2014976441,2
    --42390599(+) AGCCCG/TCTTCT 2 -- int10--------
    rs784497861,2
    C--42390660(+) ACACAA/CCATCC 4 N T mis10--------
    rs2002885501,2
    C--42390746(+) GCCACA/GACAGT 3 N D mis1 int10--------
    rs1884502961,2
    C--42390786(+) CACACA/CTACCC 2 -- ut31 int10--------
    rs1813452781,2
    --42390855(+) TCCCAC/GAGGCC 2 -- ut31 int10--------
    rs60025681,2
    C,F--42390961(+) TGTGCG/ATGCAG 2 -- ut31 int1 ese31Minor allele frequency- A:0.00CSA 1
    rs170027871,2
    C,F,H--42391017(+) TTGGCT/GCCTCC 2 -- ut31 int1 ese316Minor allele frequency- G:0.13NA NS EA WA CSA 1630
    rs96116981,2
    A,H--42391085(+) ACTCAG/AGAGAT 2 -- ut31 int1 ese34Minor allele frequency- A:0.00NS EA 420
    rs1333021,2
    C,F,O,A,H--42391176(+) GGCTAC/TAGAGA 2 -- ut31 int1 ese327Minor allele frequency- T:0.30MN NA EA NS WA CSA 2850
    rs1405027661,2
    --42391313(+) AGAAGA/GCAGAG 2 -- ut31 int10--------
    rs1879835871,2
    --42391578(+) TTCCTC/TTTAGA 2 -- ut31 int10--------
    rs1809069671,2
    --42391691(+) CAGTAC/TAAACA 2 -- ut31 int10--------
    rs1870703991,2
    --42391994(+) TTCTCC/TGTCAG 2 -- ut31 int10--------
    rs60025691,2
    H--42392046(+) GCTTCA/CTACAT 2 -- ut31 int1 ese34Minor allele frequency- C:0.00NS EA 420
    rs557588791,2
    C,F--42392091(+) GTGCTG/AAAGCT 2 -- ut31 int11Minor allele frequency- A:0.03NA 120
    rs560414481,2
    C--42392104(+) TCATAA/TTTATG 2 -- ut31 int10--------
    rs117045111,2
    H--42392114(+) GTCTGG/TCTTTC 2 -- ut31 int10--------
    rs788454851,2
    C,F--42392152(+) CTGACT/GCCTGT 2 -- ut31 int11Minor allele frequency- G:0.06EA 120
    rs1161400241,2
    C,F--42392173(+) AATGAT/CACCCA 2 -- ut31 int11Minor allele frequency- C:0.01WA 118
    rs1923581361,2
    --42392329(+) GCCTTA/GGGGAA 2 -- ut31 int10--------
    rs1816773301,2
    --42392390(+) CCCATC/TTCCTG 2 -- ut31 int10--------
    rs1862061231,2
    --42392404(+) CAGCCC/TAGGTG 2 -- ut31 int10--------
    rs7101941,2
    C,F,A,H--42392560(+) CTATGG/CTCTCG 2 -- ut31 int1 ese331Minor allele frequency- C:0.20MN NS EA NA WA CSA 2760
    rs1902374741,2
    --42392602(+) ATCCTC/TCCTTG 2 -- ut31 int10--------
    rs1480884841,2
    --42392695(+) AGGGAA/TCCTTG 2 -- ut31 int10--------
    rs1418722731,2
    C--42392704(+) TGGCTA/GCTGTA 2 -- ut31 int10--------
    rs1506460351,2
    --42392723(+) CCTGTA/TTGGAG 2 -- ut31 int10--------
    rs3749101501,2
    ----42387067(+) CGGTC-/CAAA  
            
    AAACA
    2 -- int10--------
    rs3740669811,2
    ----42386929(+) TGGGCA/GTGGTG 2 -- int10--------
    rs3698260451,2
    ----42388882(+) CAGCCA/GATTCT 2 -- int10--------
    rs3726759141,2
    ----42373030(+) CGCCCA/GGAGCA 2 -- ut510--------
    rs3730568181,2
    ----42383319(+) TTTGCC/GCTAAA 2 -- int10--------
    rs607860571,2
    ----42386414(+) GGAGGC/GGCGAT 2 -- int10--------
    rs3700227321,2
    ----42375906(+) CCTGTA/CGGTTG 2 -- int10--------
    rs1995080821,2
    ----42377174(+) AGCCAA/GGGCAA 2 -- int10--------
    rs200