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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

SEPT3 Gene

protein-coding   GIFtS: 48
GCID: GC22P042372

septin 3


(Previous symbol: SEP3)
  Search for SEPT3
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Biological research products
for SEPT3    

Aliases
for SEPT3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Septin 31 2
SEP31 2 3 5
BK250D10.31
Neuronal-Specific Septin 32
Neuronal-Specific Septin-32

External Ids:    HGNC: 107501   Entrez Gene: 559642   Ensembl: ENSG000001001677   OMIM: 6083145   UniProtKB: Q9UH033   

Export aliases for SEPT3 gene to outside databases

Previous GC identifers: GC22P038987 GC22P040616 GC22P040697 GC22P025339


Summaries
for SEPT3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for SEPT3:
This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is
upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been
determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)

Gene Wiki entry for SEPT3


Genomic Views
for SEPT3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.1  NT_011520.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the SEPT3 gene promoter:
         USF1   USF2   STAT5A   USF-1:USF-2   C/EBPalpha   Pax-3   USF-1   c-Myb   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for SEPT3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat SEPT3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

SEPT3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
SEPT3 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P042372:  view genomic region     (about GC identifiers)

Start:
 42,372,276 bp from pter      End:
 42,394,225 bp from pter
Size:
 21,950 bases      Orientation:
 plus strand

Proteins
for SEPT3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03 (See protein sequence)
Recommended Name: Neuronal-specific septin-3  
Size: 358 amino acids; 40704 Da
Subunit: Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with
cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By
similarity)
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Cell junction, synapse (By similarity)
Sequence caution: Sequence=AAG00517.1; Type=Erroneous initiation; Sequence=AAG00518.1; Type=Erroneous initiation;
Sequence=AAG00519.1; Type=Erroneous initiation; Sequence=AAI11780.2; Type=Erroneous initiation; Sequence=CAD38797.1;
Type=Erroneous initiation; Sequence=CAG30458.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for SEPT3:
3SOP (3D)    
Secondary accessions: B1AHR0 Q2NKJ7 Q59GF7 Q6IBZ6 Q8N3P3 Q9HD35
Alternative splicing: 3 isoforms:  Q9UH03-1   Q9UH03-2   Q9UH03-3   

Explore the universe of human proteins at neXtProt for SEPT3: NX_Q9UH03

Post-translational modifications:

  • Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91 (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UH03

    • SEPT3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_061979.3  NP_663786.2  

    ENSEMBL proteins: 
     ENSP00000391416   ENSP00000379704   ENSP00000383956   ENSP00000379703   ENSP00000379695  
     ENSP00000291236   ENSP00000332866  

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol ----
    GO:0019717synaptosome ----
    GO:0030054cell junction IEA--
    GO:0031105septin complex IEA--
    GO:0042734presynaptic membrane ----


    SEPT3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for SEPT3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    SEPT3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000038 Cell_div_GTP-bd
     IPR008114 Septin3
     IPR016491 Septin

    Graphical View of Domain Structure for InterPro Entry Q9UH03

    ProtoNet protein and cluster: Q9UH03

    2 Blocks protein families:
    IPB000038 Cell division/GTP binding protein
    IPB008114 Septin 3 signature


    UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
    Similarity: Belongs to the septin family


    Function
    for SEPT3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
    Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)
    Induction: Up-regulated during neuronal differentiation

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat SEPT3
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    hsa-miR-642a hsa-miR-1321 hsa-miR-146a hsa-miR-128 hsa-miR-30d hsa-miR-578 hsa-miR-342-3p hsa-miR-30a
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for SEPT3

    In Situ Assay
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         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for SEPT3

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005525GTP binding IEA--


    SEPT3 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for SEPT3: Sept3tm1Keng Sept3tm1Wtr
         2 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Sept3):
     nervous system  normal 

    SEPT3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for SEPT3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for SEPT3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    5/36 Interacting proteins for SEPT3 (Q9UH032, 3 ENSP000003797044) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WBP2Q969T92, 3, ENSP000002548064MINT-65566 I2D: score=4 STRING: ENSP00000254806
    MAPK6Q166592, 3MINT-8261912 I2D: score=2 
    PRKG1Q139763, ENSP000003630924I2D: score=1 STRING: ENSP00000363092
    SEPT11Q9NVA23, ENSP000002648934I2D: score=1 STRING: ENSP00000264893
    SEPT6Q141413, ENSP000003415244I2D: score=1 STRING: ENSP00000341524
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis NAS--
    GO:0007049cell cycle IEA--


    SEPT3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for SEPT3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    SEPT3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for SEPT3
    2 Novoseek chemical compound relationships for SEPT3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoic acid 38.4 1 15200239 (1)
    serine 25.9 1 15107017 (1)

    Search CenterWatch for drugs/clinical trials and news about SEPT3 

    Transcripts
    for SEPT3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for SEPT3 gene (3 alternative transcripts): 
    NM_019106.5  NM_145733.2  NM_145734.1  

    Unigene Cluster for SEPT3:

    Septin 3
    Hs.120483  [show with all ESTs]
    Unigene Representative Sequence: NM_019106
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449288 ENST00000396426(uc003bbr.4) ENST00000406029 ENST00000396425(uc003bbs.4 uc011apj.2)
    ENST00000396417 ENST00000460267 ENST00000291236 ENST00000328414(uc010gys.3)


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    8/86 QIAGEN miScript miRNA Assays for microRNAs that regulate SEPT3 (see all 86):
    hsa-miR-642a hsa-miR-1321 hsa-miR-146a hsa-miR-128 hsa-miR-30d hsa-miR-578 hsa-miR-342-3p hsa-miR-30a
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene shRNA RFP: SEPT3
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    Clone
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    Primer
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    Additional cDNA sequence: 

    AB209152.1 AF285107.1 AF285108.1 AF285109.1 AK290037.1 AK299919.1 AL833942.1 BC111779.1 
    CR456572.1 

    13 DOTS entries:

    DT.86840677  DT.100683348  DT.100819854  DT.95270345  DT.100819858  DT.120642986  DT.120642993  DT.120643001 
    DT.101965960  DT.120643014  DT.403287  DT.92423021  DT.92423023 

    24/214 AceView cDNA sequences (see all 214):

    BX345218 BX280551 D54252 BP348877 BQ937737 CA388736 CR611488 T33727 
    BU731445 BM771185 CR456572 BQ071318 BM666855 BM695073 BM449683 CR456400 
    BM708052 NM_145733 BE891766 BP348363 AI369698 AA812560 AF285107 AA812559 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT3 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                -                                                                                       
    SP2:                                -                                                                             -         
    SP3:                                -     -     -     -                       -     -                             -         
    SP4:        -     -     -           -                                                                                       
    SP5:                                -                                                                                       


    ECgene alternative splicing isoforms for SEPT3

    Expression
    for SEPT3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    SEPT3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AATGTTTGCG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See SEPT3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for SEPT3

    SOURCE GeneReport for Unigene cluster: Hs.120483

    UniProtKB/Swiss-Prot: SEPT3_HUMAN, Q9UH03
    Tissue specificity: Brain-specific

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    In Situ
    Assay Products:     
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    Orthologs
    for SEPT3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals and fungi.

    Orthologs for SEPT3 gene from 5/22 species (see all 22)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves SEPT31 septin 3 84.57(n)
    94.64(a)    		   427899  XM_425473.3  XP_425473.3 
    lizard
    (Anolis carolinensis)    		 Reptilia SEPT36
    		 --
    		 92(a)
    		 1 ↔ 1
    		 5(27025259-27033459)
    zebrafish
    (Danio rerio)    		 Actinopterygii sept36
    CABZ01061914.26
    		 --
    		 78(a)
    32(a)
    		 1 ↔ 1
    possible ortholog
    		 1(46087335-46104648)
    19(12015392-12049272)
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-596
    		 UNCoordinated family member (unc-59)
    		 28(a)
    		 possible ortholog
    		 I(13629214-13633485)
    baker's yeast
    (Saccharomyces cerevisiae)    		 Saccharomycetes CDC10(YCR002C)4
    CDC101    		 Component of the septin ring that is required for cytokinesis; more4
    Cdc10p1    		 52.31(n)1
    47.92(a)1    		   3(118348-117380)4
    8503581, 4  NP_009928.11, 4 


    ENSEMBL Gene Tree for SEPT3 (if available)
    TreeFam Gene Tree for SEPT3 (if available) 

    Paralogs
    for SEPT3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for SEPT3 gene
    SEPT92  SEPT142  SEPT42  SEPT12  SEPT72  SEPT122  SEPT62  SEPT7L2  
    SEPT112  SEPT22  SEPT102  SEPT82  SEPT52  
    17 SIMAP similar genes for SEPT3 using alignment to 5 protein entries:     SEPT3_HUMAN (see all proteins):
    SEPT9    SEPT12    MAFK    Nbla02942    SEPT4    SEPT2
    DKFZp686F17268    SEPT7    SEPT7L    SEPT1    SEPT5    SEPT6
    SEPT11    DKFZp547B243    SEPT10    SEPT14    SEPT8

    SEPT3 for paralogs           About GeneDecksing



    Genomic Variants
    for SEPT3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/390 NCBI SNPs in SEPT3 are shown (see all 390)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 22 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1835183431,2
    		--42370931(+) CTAGCA/GCTTTA 2 -- us2k10--------
    rs57511911,2
    		C,F,A,H,--42370991(+) TGAGAC/TAATGA 2 -- us2k1 tfbs322Minor allele frequency- T:0.50NS EA NA WA 2518
    rs796226961,2
    		C,F,--42371137(+) GCCTTG/ATATAT 2 -- us2k11Minor allele frequency- A:0.14WA 118
    rs1870357651,2
    		--42371194(+) GACATC/TCATTT 2 -- us2k10--------
    rs48204511,2
    		C,F,--42371333(+) AGTTTC/TTGGGT 2 -- us2k1 tfbs312Minor allele frequency- T:0.24NA WA CSA EA 376
    rs1903735631,2
    		--42371499(+) GCAGCA/CCAGCC 2 -- us2k10--------
    rs1821868831,2
    		--42371500(+) CAGCCC/TAGCCC 2 -- us2k10--------
    rs1869659661,2
    		--42371502(+) GCCCAA/GCCCTG 2 -- us2k10--------
    rs1930820931,2
    		--42371609(+) ACTGAC/TTCCTG 2 -- us2k10--------
    rs1147028481,2
    		C,F,--42371662(+) TTTATT/CAGGTG 2 -- us2k11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for SEPT3 (42372276 - 42394225 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for SEPT3: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for SEPT3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    SEPT3 for disorders           About MalaCards

    SEPT3 for disorders           About GeneDecksing

    OMIM gene information: 608314    OMIM disorders: --

    1 Novoseek disease relationship for SEPT3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    teratocarcinoma 71.8 1 15200239 (1)

    Human Genome Epidemiology (HuGE) Navigator: SEPT3 (1 document)

    Export disorders for SEPT3 gene to outside databases

    Publications
    for SEPT3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for SEPT3 gene, integrated from 9 sources (see all 25) (see top 10):
    (articles sorted by number of sources associating them with SEPT3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human septin 3 on chromosome 22q13.2 is upregulated by neuronal differentiation. (PubMed id 11322766)1, 2, 9 Methner A.... Lewerenz J. (2001)
    2. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    3. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    4. Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals. (PubMed id 15107017)1, 9 Xue J....Robinson P.J. (2004)
    5. Septin 3 gene polymorphism in Alzheimer's disease. (PubMed id 15200238)1, 9 Takehashi M....Ueda K. (2004)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. A draft of the human septin interactome. (PubMed id 21082023)1 Nakahira M....Kobarg J. (2010)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    11. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    12. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
    13. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
    14. Expression profiling the human septin gene family. (PubMed id 15915442)2 Hall P.A....Russell S.E. (2005)
    15. Septin 3 (G-septin) is a developmentally regulated phosphoprotein enriched in presynaptic nerve terminals. (PubMed id 15485489)1 Xue J....Robinson P.J. (2004)
    16. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    17. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
    18. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    19. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1 Wiemann S.... Poustka A. (2001)
    20. DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (2000)
    21. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
    22. Retroviral promoter-trap insertion into a novel mammalian septin gene expressed during mouse neuronal development. (PubMed id 10446280)9 Xiong J.W....Stuhlmann H. (1999)
    23. Expression of septin 3 isoforms in human brain. (PubMed id 15200239)9 Takehashi M....Ueda K. (2004)

    External Searches for SEPT3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing SEPT3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55964 HGNC: 10750 AceView: SEPT3andMGC26816 Ensembl:ENSG00000100167 euGenes: HUgn55964
    ECgene: SEPT3 H-InvDB: SEPT3

    Other Databases showing SEPT3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing SEPT3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for SEPT3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for SEPT3 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for SEPT3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for SEPT3 gene:
    Search GeneIP for patents involving SEPT3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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