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SEPT2 Gene

protein-coding GIFtS: 60

GC02P241975

septin 2
(Previous names: neural precursor cell expressed, developmentally down-regulated 5 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: DIFF6, NEDD5)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DIFF6 ^², ³, ⁵
KIAA0158 ^¹, ², ³
NEDD-5 ^³
NEDD5 ^², ³, ⁵
OTTHUMP00000164575 ^²
Pnutl3 ^¹, ²
hNedd5 ^¹, ²

Descriptions
Neural precursor cell expressed developmentally down-regulated protein 5 ^³
neural precursor cell expressed, developmentally down-regulated 5 ^¹, ²
septin 2 ^²

External Ids
HGNC: 7729¹
Entrez Gene: 4735²
UniProtKB: Q15019³
Ensembl: ENSG00000168385⁷

Search outside databases for aliases for SEPT2 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: SEPT2_HUMAN, Q15019

Function: Required for normal progress through mitosis. Involved in cytokinesis

Gene Wiki entry for SEPT2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the SEPT2 gene

Entrez Gene cytogenetic band: 2q37 Ensembl cytogenetic band: 2q37.3 HGNC cytogenetic band: 2q37.3

SEPT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P241975: (about GC identifiers)

Start:	241,903,396 bp from pter
End:	241,942,115 bp from pter
Size:	38,720 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000002.10 NT_005416.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: SEPT2_HUMAN, Q15019 (See protein sequence)

Recommended Name: Septin-2

Size: 361 amino acids; 41487 Da

Subunit: Monomer, and homodimer. Nucleotide binding promotes dimerization. Heterohexamer composed

of two heterotrimers containing one copy each of SEPT2, SEPT6 and SEPT7. The asymmetrical

heterotrimers associate head-to-head to form a hexameric unit that assembles into filaments

Subcellular location: Cytoplasm. Spindle. Note=Accumulates near the contractile ring from anaphase

through telophase, and finally condenses into the midbody. In interphase and postmitotic cells,

localised to fibrous or granular structures, depending on the growth state of the cell (By

similarity)

PDB structures from and Proteopedia :

2QA5 (3D)

2QAG (3D)

2QNR (3D)

Secondary accessions: Q14132 Q8IUK9 Q96CB0

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (4 alternative transcripts):

NP_001008491.1 NP_001008492.1 NP_004395.1 NP_006146.1

ENSEMBL proteins:

ENSP00000353157 ENSP00000375834 ENSP00000375832 ENSP00000375833 ENSP00000385387 ENSP00000384861

ENSP00000385109 ENSP00000385172 ENSP00000384525 ENSP00000386001

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Septin 2)
	Human Recombinant Proteins from Abnova (SEPT2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	10942595
GO:0005737	cytoplasm	IDA	10942595
GO:0005819	spindle	IEA	--
GO:0031105	septin complex	IEA	--

About this table

Antibodies for SEPT2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for SEPT2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Septin 2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (SEPT2)
	Novus Biologicals Antibodies for SEPT2

Assays for SEPT2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q15019

ProtoNet protein and cluster: Q15019

2 Blocks protein families:

IPB000038 Cell division/GTP binding protein

IPB008113 Septin 2 signature

UniProtKB/Swiss-Prot: SEPT2_HUMAN, Q15019

Similarity: Belongs to the septin family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SEPT2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001008491

Applied Biosystems Silencer® siRNAs for SEPT2

Sigma-Aldrich siRNA and siRNA Panels for SEPT2

Sigma-Aldrich shRNA for SEPT2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for SEPT2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001008491
Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001008491
untagged cDNA clones in CMV expression vector (see all 5): AK025163

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001008491

UniProtKB/Swiss-Prot: SEPT2_HUMAN, Q15019

Function: Required for normal progress through mitosis. Involved in cytokinesis

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0005515	protein binding	IPI	10321247 17685441
GO:0005525	GTP binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for SEPT2

5/7 Interacting proteins for SEPT2 (ENSP00000353157³ Q15019^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SEPT6	Q14141¹	STRING (score=.998) EBI-741220, EBI-745901
PIK3R1	P27986²	STRING (score=.763) MINT-3378272
SEPT11	Q9NVA2¹	EBI-741220, EBI-957999
SEPT8	Q92599¹	EBI-741220, EBI-958021
DAZAP2	Q15038²	MINT-66147

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007049	cell cycle	IEA	--
GO:0007067	mitosis	IEA	--
GO:0051301	cell division	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for SEPT2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (SEPT2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (SEPT2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001008491

Sigma-Aldrich siRNA and siRNA Panels for SEPT2

Sigma-Aldrich shRNA for SEPT2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001008491 NM_001008492 NM_004404 NM_006155

REFSEQ mRNAs for SEPT2 gene (4 alternative transcripts):

NM_001008491.1 NM_001008492.1 NM_004404.3 NM_006155.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001008491 NM_001008492 NM_004404 NM_006155

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001008491
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001008491
                                 untagged cDNA clones in CMV expression vector (see all 5): AK025163

Additional cDNA sequence:

AF038404.1 AK025163.1 AK294563.1 BC014455.1 BC033559.1 BC040676.1 BC043180.1 BX648000.1

CR589975.1 CR593579.1 CR608761.1 CR625560.1 D28540.1 D63878.1

24/85 DOTS entries (see all 85 ):

DT.100033375 DT.91773953 DT.100684920 DT.91915294 DT.91959159 DT.100684911 DT.87012262 DT.91773966

DT.91773947 DT.100684906 DT.120964381 DT.92413358 DT.100684922 DT.100684905 DT.100684915 DT.87017681

DT.75172050 DT.120964489 DT.100684916 DT.100847908 DT.91773961 DT.95272772 DT.100684914 DT.91727308

24/1255 AceView cDNA sequences (see all 1255 ):

BM475821 AI752921 CF995789 BM723567 BM988455 N67234 AW469297 AU122543

AI074412 BQ000901 AW517043 AI383938 CD657011 AI468179 AI540722 AA150689

BE348968 AU130880 AI864579 AU139822 AI720309 AI580723 BE044063 T36137

highest scoring ESTs for SEPT2:

D63878 AA011596 AA027297 AA027298 AA029716 AA034310 AA034311 AA053534 AA071158 AA127717

Unigene Cluster for SEPT2:

Septin 2

Hs.716403 [show with all ESTs]

Unigene Representative Sequence: NM_001008491

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for SEPT2 (see all 11 )

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8a	·	8b	·	8c	·	8d	·	8e	^	9a	·	9b	·	9c	^	10a	·	10b	·	10c	^	11a	·	11b	^	12a	·	12b	·	12c	^	13a	·
SP1:																	-		-		-						-
SP2:																																															-		-		-
SP3:									-		-		-				-		-		-						-
SP4:																	-		-		-						-
SP5:			-		-		-		-		-						-		-								-

ExUns:	13b	^	14	^	15	^	16a	·	16b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for SEPT2

10 Ensembl transcripts including schematic representations:

ENST00000360051 ENST00000391973 ENST00000391971 ENST00000391972 ENST00000402251 ENST00000406494

ENST00000401990 ENST00000402092 ENST00000407971 ENST00000407017

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

SEPT2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for SEPT2

¹ / ² / ³

12 probe-sets matching SEPT2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40281_at²^{, 3}	U95-A	1	1.00	1.00	0.78	1.46	D63878	1.00	1.00	1.00	1
73920_at²^{, 3}	U95-E	1	1.00	1.00	0.83	0.48	AI015194	0.60	1.00	0.82	1
73382_at²^{, 3}	U95-D	1	0.31	1.00	0.72	1.10	AI829450	0.40	1.00	0.76	1
73219_at*²^{, 3}	U95-E	1	1.00	1.00	0.49	0.96	AI377413	0.40	1.00	0.76	1
200778_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI191427	0.80	1.00	0.91	1
200015_s_at²^{, 3}	U133-B	1	1.00	1.00	--	--	NM_004404	0.60	1.00	0.82	1
232637_at*²^{, 3}	U133-B	1	1.00	1.00	--	--	AK025163	0.20	1.00	0.72	1
1559038_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200778_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1554747_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200015_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
232637_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks SEPT2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CGGAGTCCAT

SOURCE GeneReport for Unigene cluster: Hs.716403

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for SEPT2 gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	SEPT2¹	--	septin 2	89.94(n) 98.6(a)	487886 XM_846816.1 XP_851909.1
chimpanzee (Pan troglodytes)	SEPT2¹	--	septin 2	99.45(n) 100(a)	460082 XM_516208.2 XP_516208.2
cow (Bos taurus)	SEPT2¹	--	septin 2	88.55(n) 97.78(a)	511612 NM_001046092.1 NP_001039557.1
rat (Rattus norvegicus)	Sept2¹	--	septin 2	89.29(n) 98.06(a)	117515 NM_057148.2 NP_476489.1
mouse (Mus musculus)	Sept2^{1, 5}	1⁵	septin 2^{1, 5}	90.03(n)¹ 98.61(a)¹	18000¹ NM_010891.1¹ NP_035021.1¹ AK028072⁵ AK146616⁵ (see all 21)

About this table Species with no ortholog for SEPT2

ENSEMBL Gene Tree for SEPT2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for SEPT2 gene

ENSG00000214765² ENSG00000120555² LOC441601² SEPT7²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/200 NCBI SNPs in SEPT2 are shown (see all 200 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 62)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs14351^1,2	A,C,F,H	241941051(+)	`TGGGCT/GTGCCC`	4	--	ut3¹		7		MN EU EA WA	950
	rs7568^1,2	A,C,F,H	241940416(+)	`GATTTA/GCCATA`	4	--	ut3¹		18		MN EA CSAM EU WA	3466
--	rs1056801^1,2	C,F	241940980(+)	`CACTTT/CAGTGT`	4	--	ut3¹		1		MN	184
--	rs3755394^1,2	F,H	241941882(+)	`CGCTGC/ACTCCT`	4	--	ut3¹ ese³		5		EA EU WA	1698
--	rs6672^1,2	A,F	241941694(+)	`AAGCTA/GTATGT`	4	--	ut3¹		1		MN	184
--	rs5022214^1,2	F,H	241940952(-)	`AGGTTG/TGATTC`	4	--	ut3¹ ese³		4		EU EA WA	388
--	rs12078^1,2	C	241941529(+)	`TGCTTA/GATCTG`	4	--	ut3¹ ese³		1		MN	184
--	rs15936^1,2	F	241941698(-)	`CATAAC/AATATA`	4	--	ut3¹		1		MN	184
	rs11554047^1,2	C	241940595(-)	`GCAGAC/TGAATC`	4	--	ut3¹ ese³		0	--	--	--	--
	rs8613^1,2	C	241942042(+)	`AACACT/GTATTT`	4	--	ut3¹		1		MN	184

About this table

HapMap Linkage Disequilibrium images for SEPT2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601506

Human Genome Epidemiology Navigator: SEPT2 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/50 PubMed articles for SEPT2 gene (see all 50 ):

Isolation and mapping of a human gene (DIFF6) homologous to yeast CDC3, CDC10, CDC11, and CDC12, and mouse Diff6. (PubMed id 8697812)^{2, 3, 4} Mori T.... Nakamura Y. (1996)
Septin 2 phosphorylation: theoretical and mass spectrometric evidence for the existence of a single phosphorylation site in vivo. (PubMed id 15150837)^{1, 3, 4} She Y.M.... Trimble W.S. (2004)
Structural insight into filament formation by mammalian septins. (PubMed id 17637674)^{3, 4} Sirajuddin M....Wittinghofer A. (2007)
Phosphoproteome analysis of the human mitotic spindle. (PubMed id 16565220)^{3, 4} Nousiainen M.... Koerner R. (2006)
Phosphoproteomic analysis of the human pituitary. (PubMed id 16807684)^{3, 4} Beranova-Giorgianni S.... Giorgianni F. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)^{3, 4} Rush J.... Comb M.J. (2005)
A mitotic septin scaffold required for Mammalian chromosome congression and segregation. (PubMed id 15774761)^{3, 4} Spiliotis E.T....Nelson W.J. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8590280)^{3, 4} Nagase T....Nomura N. (1995)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4735	HGNC: 7729	AceView: NEDD5	Ensembl:ENSG00000168385	euGenes: HUgn4735
ECgene: SEPT2	H-InvDB: SEPT2

(According to HUGE)
About This Section

HUGE: KIAA0158

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for SEPT2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for SEPT2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for SEPT2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for SEPT2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for SEPT2		Antibodies for SEPT2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for SEPT2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (SEPT2)
	Antibodies (SEPT2)
	Chimera RNAi (SEPT2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (Septin 2)
	Antibodies (Septin 2)

Search OriGene for SEPT2

Search Tocris compounds for SEPT2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for SEPT2

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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SEPT2 Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for SEPT2

Summaries
for SEPT2

Genomic Location
for SEPT2

Proteins
for SEPT2

Protein Domains/
Families
for SEPT2

Gene Function
for SEPT2

Pathways & Interactions
for SEPT2

Drugs & Compounds
for SEPT2

Transcripts
for SEPT2

Expression
for SEPT2

Orthologs
for SEPT2

Paralogs
for SEPT2

SNPs/Variants
for SEPT2

Disorders & Mutations
for SEPT2

Medical News
for SEPT2

Publications
for SEPT2

Search for SEPT2

Genome Databases showing SEPT2

Other Databases showing SEPT2

Specialized Databases showing SEPT2

Licensable Technologies
for SEPT2

Services
for SEPT2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

SEPT2 Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor SEPT2

Summariesfor SEPT2

Genomic Locationfor SEPT2

Proteinsfor SEPT2

Protein Domains/Familiesfor SEPT2

Gene Functionfor SEPT2

Pathways & Interactionsfor SEPT2

Drugs & Compoundsfor SEPT2

Transcriptsfor SEPT2

Expression for SEPT2

Orthologsfor SEPT2

Paralogsfor SEPT2

SNPs/Variantsfor SEPT2

Disorders & Mutationsfor SEPT2

Medical Newsfor SEPT2

Publicationsfor SEPT2

Search for SEPT2

Genome Databases showing SEPT2

Other Databases showing SEPT2

Specialized Databases showing SEPT2

Licensable Technologiesfor SEPT2

Servicesfor SEPT2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for SEPT2

Summaries
for SEPT2

Genomic Location
for SEPT2

Proteins
for SEPT2

Protein Domains/
Families
for SEPT2

Gene Function
for SEPT2

Pathways & Interactions
for SEPT2

Drugs & Compounds
for SEPT2

Transcripts
for SEPT2

Expression
for SEPT2

Orthologs
for SEPT2

Paralogs
for SEPT2

SNPs/Variants
for SEPT2

Disorders & Mutations
for SEPT2

Medical News
for SEPT2

Publications
for SEPT2

Licensable Technologies
for SEPT2

Services
for SEPT2