External Ids for SEPT12 Gene
Previous GeneCards Identifiers for SEPT12 Gene
This gene encodes a guanine-nucleotide binding protein and member of the septin family of cytoskeletal GTPases. Septins play important roles in cytokinesis, exocytosis, embryonic development, and membrane dynamics. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for SEPT12 Gene
SEPT12 (Septin 12) is a Protein Coding gene. Diseases associated with SEPT12 include Spermatogenic Failure 10 and Non-Syndromic Male Infertility Due To Sperm Motility Disorder. Among its related pathways are Bacterial invasion of epithelial cells. GO annotations related to this gene include protein homodimerization activity and GTP binding. An important paralog of this gene is SEPT6.
UniProtKB/Swiss-Prot for SEPT12 Gene
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).